Detector for saturation of bilirubin adsorption column

Abstract

The utility model discloses a bilirubin adsorption column saturation detector, which relates to the technical field of bilirubin adsorption treatment and comprises a light-emitting device and a detection device, the light-emitting device is provided with a first light-emitting end and a second light-emitting end, and the detection device is provided with a first detection end and a second detection end. The first light-emitting end is constructed to enable light to penetrate through a plasma input tube of the bilirubin adsorption column and irradiate the first detection end, the first detection end is used for detecting the illumination intensity of the light penetrating through the plasma input tube, and the second light-emitting end is constructed to enable light to penetrate through a plasma output tube of the bilirubin adsorption column and irradiate the second detection end; the second detection end is used for detecting the illumination intensity of the light passing through the plasma output tube. The detector can more accurately detect the saturation of the adsorption column in real time in the adsorption treatment process of the adsorption column.

Description

Technical Field

[0001] The utility model relates to the technical field of bilirubin adsorption therapy, in particular to a bilirubin adsorption column saturation detector. Background Art

[0002] Bilirubin is the main product of hemoglobin metabolism. Patients with severe hepatitis often develop hyperbilirubinemia due to their inability to metabolize bilirubin in a timely manner. Bilirubin adsorption is an important method for treating hyperbilirubinemia in severe hepatitis. A variety of adsorption columns are currently used in clinical practice, but there is no device that can detect the real-time saturation of the adsorption column during bilirubin adsorption therapy. In actual operation, relying solely on past experience, adsorption therapy reaches saturation after approximately 3000-5000ml of plasma. If the bilirubin adsorption column is terminated before saturation, the adsorption material on the bilirubin adsorption column will be wasted. If adsorption therapy is continued after the bilirubin adsorption column has reached saturation, the adsorption effect of the adsorption column will be weakened, reducing the therapeutic effect on the patient and increasing the risk of treatment. Therefore, there is an urgent need for a bilirubin adsorption column saturation detector that can more accurately detect the saturation of the adsorption column in real time during adsorption therapy. Utility Model Content

[0003] The purpose of the utility model is to provide a bilirubin adsorption column saturation detector to solve the problems existing in the above-mentioned prior art and to be able to more accurately detect the saturation of the adsorption column in real time during the adsorption treatment process of the adsorption column.

[0004] To achieve the above purpose, the present invention provides the following solutions:

[0005] The utility model provides a bilirubin adsorption column saturation detector, comprising: a light-emitting device and a detection device, the light-emitting device having a first light-emitting end and a second light-emitting end, the detection device having a first detection end and a second detection end, the first light-emitting end being configured to allow light to pass through the plasma in the plasma input tube of the bilirubin adsorption column and irradiate the first detection end, the first detection end being used to detect the light intensity of the light passing through the plasma input tube, the second light-emitting end being configured to allow light to pass through the plasma in the plasma output tube of the bilirubin adsorption column and irradiate the second detection end, the second detection end being used to detect the light intensity of the light passing through the plasma output tube.

[0006] Preferably, the first light-emitting end and the first detection end are arranged opposite to each other and have a gap therebetween, the second light-emitting end and the second detection end are arranged opposite to each other and have a gap therebetween, the plasma input tube is used to pass through between the first light-emitting end and the first detection end, and the plasma output tube is used to pass through between the second light-emitting end and the second detection end.

[0007] Preferably, it further includes a first light-shielding sleeve and a second light-shielding sleeve, the first light-shielding sleeve is used to be sleeved on the plasma input tube, and the second light-shielding sleeve is used to be sleeved on the plasma output tube, and the first light-shielding sleeve and the second light-shielding sleeve are both provided with two through holes opposite to each other, the first light-emitting end and the first detection end respectively extend into the two through holes of the first light-shielding sleeve, and the second light-emitting end and the second detection end respectively extend into the two through holes of the second light-shielding sleeve.

[0008] Preferably, it further includes a first light-shielding sleeve and a second light-shielding sleeve, the first light-shielding sleeve is used to be sleeved on the plasma input tube, and the second light-shielding sleeve is used to be sleeved on the plasma output tube, and the first light-shielding sleeve and the second light-shielding sleeve are both provided with two through holes opposite to each other, the first light-emitting end and the first detection end respectively pass through the two through holes of the first light-shielding sleeve and extend into the first light-shielding sleeve, and the second light-emitting end and the second detection end respectively pass through the two through holes of the second light-shielding sleeve and extend into the second light-shielding sleeve.

[0009] Preferably, the wavelength of the light emitted by the light emitting device is 430nm-490nm.

[0010] Preferably, the light emitting device includes a laser generator and two optical fibers, one end of each of the two optical fibers is connected to the output end of the laser generator, and the other end of each of the two optical fibers forms the first light emitting end and the second light emitting end.

[0011] Preferably, the detection device includes a data processor and two detection heads, the two detection heads are signal-connected to the data processor, the two detection heads respectively form a first detection end and a second detection end, the two detection heads can respectively detect the intensity of light passing through the plasma input tube and the plasma output tube and transmit the signal to the data processor, and the data processor can calculate the saturation of the bilirubin adsorption column based on the light intensity measured by the two detection heads.

[0012] Preferably, it further includes a plurality of indicator lights, the data processor is in communication connection with the indicator lights, different indicator lights are used to indicate different saturations, and the data processor controls the corresponding indicator lights to light up according to the saturation of the bilirubin adsorption column.

[0013] Compared with the prior art, the utility model has achieved the following technical effects:

[0014] The utility model provides a bilirubin adsorption column saturation detector, in which the light emitted by the first light-emitting end passes through the plasma input tube of the bilirubin adsorption column and is irradiated on the first detection end, and the first detection end can detect the light intensity after the light passes through the plasma input tube, and the light emitted by the second light-emitting end passes through the plasma output tube of the bilirubin adsorption column and is irradiated on the second detection end, and the second detection end can detect the light intensity after the light passes through the plasma output tube. During the bilirubin adsorption treatment, the first light-emitting end, the first detection end, the second light-emitting end and the second detection end remain in an open state, and the staff can infer the real-time saturation of bilirubin in the adsorption column based on the light intensity obtained by the first detection end and the second detection end, thereby realizing accurate detection of the bilirubin saturation in the adsorption column. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0016] Figure 1 This is a schematic diagram of the structure of the bilirubin adsorption column saturation detector provided by the utility model;

[0017] In the figure: 1-light-emitting device, 11-first light-emitting end, 12-second light-emitting end, 2-detection device, 21-first detection end, 22-second detection end, 3-first light-shielding cover, 4-second light-shielding cover, 5-plasma input tube, 6-plasma output tube, 7-bilirubin adsorption column, 8-optical fiber, 9-data processor. DETAILED DESCRIPTION

[0018] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0019] The purpose of the utility model is to provide a bilirubin adsorption column saturation detector to solve the problems existing in the above-mentioned prior art and to be able to more accurately detect the saturation of the adsorption column in real time during the adsorption treatment process of the adsorption column.

[0020] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0021] The utility model provides a bilirubin adsorption column saturation detector, such as Figure 1 As shown, it includes: a light-emitting device 1 and a detection device 2, the light-emitting device 1 has a first light-emitting end 11 and a second light-emitting end 12, the detection device 2 has a first detection end 21 and a second detection end 22, the first light-emitting end 11 is configured to allow light to pass through the plasma in the plasma input tube 5 of the bilirubin adsorption column 7 and irradiate the first detection end 21, the first detection end 21 is used to detect the light intensity of the light passing through the plasma input tube 5, the second light-emitting end 12 is configured to allow light to pass through the plasma in the plasma output tube 6 of the bilirubin adsorption column 7 and irradiate the second detection end 22, the second detection end 22 is used to detect the light intensity of the light passing through the plasma output tube 6.

[0022] The bilirubin adsorption column saturation detector provided by the utility model adjusts the light emitting device 1 so that the first light emitting end 11 and the second light emitting end 12 emit light of the same intensity. The light emitted by the first light emitting end 11 passes through the plasma input tube 5 of the bilirubin adsorption column 7 and is irradiated on the first detection end 21. The first detection end 21 can detect the light intensity after the light passes through the plasma input tube 5. The light emitted by the second light emitting end 12 passes through the plasma output tube 6 of the bilirubin adsorption column 7 and is irradiated on the second detection end 22. The second detection end 22 can detect the light intensity after the light passes through the plasma output tube 6. During the bilirubin adsorption treatment, the first light emitting end 11, the first detection end 21, the second light emitting end 12 and the second detection end 2 2 is turned on, the staff can infer the real-time saturation of bilirubin in the adsorption column based on the light intensity obtained by the first detection end 21 and the second detection end 22. Since the light absorption capacity of bilirubin is proportional to its own concentration, the closer the values ​​of the light intensity detected by the first detection end 21 and the second detection end 22 are, the higher the saturation of the bilirubin adsorption column 7 is, that is, when the plasma passes through the adsorption column, the adsorption column has a lower adsorption capacity for plasma; the greater the difference in the light intensity values ​​detected by the first detection end 21 and the second detection end 22, the lower the saturation of the bilirubin adsorption column 7 is, that is, when the plasma passes through the adsorption column, the adsorption column has a stronger adsorption capacity for plasma, thereby achieving accurate detection of the bilirubin saturation in the adsorption column. In the process of using the adsorption column for bilirubin adsorption treatment, the light emitting device 1 can be kept on all the time, or it can be turned on once every 5 seconds to 1 minute.

[0023] In a preferred embodiment of this embodiment, the first light-emitting end 11 and the first detection end 21 are disposed opposite each other and spaced apart, while the second light-emitting end 12 and the second detection end 22 are disposed opposite each other and spaced apart. The plasma inlet tube 5 is configured to pass between the first light-emitting end 11 and the first detection end 21, and the plasma outlet tube 6 is configured to pass between the second light-emitting end 12 and the second detection end 22. The first light-emitting end 11 and the first detection end 21 are disposed opposite each other, while the second light-emitting end 12 and the second detection end 22 are disposed opposite each other, enabling light to pass through the plasma inlet tube 5 and the plasma outlet tube 6, respectively, and illuminate the first detection end 21 and the second detection end 22.

[0024] In a preferred embodiment of this embodiment, a first light-shielding sleeve 3 and a second light-shielding sleeve 4 are further included. The first light-shielding sleeve 3 is configured to fit over the plasma inlet tube 5, and the second light-shielding sleeve 4 is configured to fit over the plasma outlet tube 6. Both the first light-shielding sleeve 3 and the second light-shielding sleeve 4 are provided with two opposing through-holes. The first light-emitting end 11 and the first detection end 21 extend into the two through-holes of the first light-shielding sleeve 3, respectively. The second light-emitting end 12 and the second detection end 22 extend into the two through-holes of the second light-shielding sleeve 4, respectively. The first light-shielding sleeve 3 and the second light-shielding sleeve 4 can block natural light to reduce the impact of external light on the test results, further improving the accuracy of the test.

[0025] In a preferred embodiment of this embodiment, a first light-shielding sleeve 3 and a second light-shielding sleeve 4 are further included. The first light-shielding sleeve 3 is configured to fit over the plasma inlet tube 5, and the second light-shielding sleeve 4 is configured to fit over the plasma outlet tube 6. The first light-shielding sleeve 3 and the second light-shielding sleeve 4 are each provided with two opposing through-holes. The first light-emitting end 11 and the first detection end 21 respectively pass through the two through-holes of the first light-shielding sleeve 3 and extend into the first light-shielding sleeve 3. The second light-emitting end 12 and the second detection end 22 respectively pass through the two through-holes of the second light-shielding sleeve 4 and extend into the second light-shielding sleeve 4. The first light-shielding sleeve 3 and the second light-shielding sleeve 4 can block natural light to reduce the impact of external light on the test results, further improving the accuracy of the test.

[0026] In a preferred embodiment of this embodiment, the wavelength of light emitted by the light emitting device 1 is 430nm-490nm. Bilirubin in plasma has a good absorption capacity for light with a wavelength of 430nm-490nm. Irradiating bilirubin with wavelengths within this range allows for good absorption of light, resulting in more accurate test results. Bilirubin in plasma has the best absorption capacity for light with a wavelength of 450nm.

[0027] In a preferred embodiment of this embodiment, the light-emitting device 1 includes a laser generator and two optical fibers 8. One end of each of the two optical fibers 8 is connected to the output end of the laser generator, and the other end of each optical fiber 8 forms a first light-emitting end 11 and a second light-emitting end 12, respectively. The wavelength and frequency of the laser light are stable, which can improve the accuracy of detection. In addition to directly using a laser generator to emit light of the corresponding wavelength, other forms of light sources can also be used, and the light is passed through a light absorber so that the light irradiated on the plasma inlet tube 5 or the plasma outlet tube 6 is of the corresponding wavelength. The light absorber is preferably a 450nm light absorber.

[0028] In order to improve the processing speed of the test results, in a preferred embodiment of this embodiment, the detection device 2 includes a data processor 9 and two detection heads. The two detection heads are signal-connected to the data processor 9. The two detection heads respectively form a first detection end 21 and a second detection end 22. The two detection heads can respectively detect the intensity of light passing through the plasma input tube 5 and the plasma output tube 6 and transmit the signal to the data processor 9. The data processor 9 can calculate the saturation of the bilirubin adsorption column 7 based on the light intensity measured by the two detection heads.

[0029] In a preferred embodiment of this embodiment, multiple indicator lights are further included. The data processor is in communication with the indicator lights. Different indicator lights are used to indicate different saturations. The data processor 9 controls the lighting of the corresponding indicator lights according to the saturation of the bilirubin adsorption column 7. The provision of indicator lights allows the operator to more intuitively understand whether the bilirubin in the adsorption column is saturated, thereby improving the convenience of use of the detector.

[0030] The present invention uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only intended to help understand the method and core concept of the present invention. At the same time, those skilled in the art will find that the specific implementation methods and application scopes may vary based on the concept of the present invention. In summary, the contents of this specification should not be construed as limiting the present invention.

Claims

1. A bilirubin adsorption column saturation detector, characterized in that: include: A light-emitting device and a detection device, wherein the light-emitting device has a first light-emitting end and a second light-emitting end, and the detection device has a first detection end and a second detection end, wherein the first light-emitting end is configured to allow light to pass through the plasma in the plasma input tube of the bilirubin adsorption column and illuminate the first detection end, and the first detection end is used to detect the light intensity of the light passing through the plasma input tube, and the second light-emitting end is configured to allow light to pass through the plasma in the plasma output tube of the bilirubin adsorption column and illuminate the second detection end, and the second detection end is used to detect the light intensity of the light passing through the plasma output tube.

2. The bilirubin adsorption column saturation detector according to claim 1, characterized in that: The first light-emitting end and the first detection end are arranged opposite to each other and have a gap therebetween, the second light-emitting end and the second detection end are arranged opposite to each other and have a gap therebetween, the plasma input tube is used to pass through between the first light-emitting end and the first detection end, and the plasma output tube is used to pass through between the second light-emitting end and the second detection end.

3. The bilirubin adsorption column saturation detector according to claim 2, characterized in that: It also includes a first light-shielding sleeve and a second light-shielding sleeve, the first light-shielding sleeve is used to be sleeved on the plasma input tube, and the second light-shielding sleeve is used to be sleeved on the plasma output tube, and the first light-shielding sleeve and the second light-shielding sleeve are both provided with two through holes opposite to each other, the first light-emitting end and the first detection end respectively extend into the two through holes of the first light-shielding sleeve, and the second light-emitting end and the second detection end respectively extend into the two through holes of the second light-shielding sleeve.

4. The bilirubin adsorption column saturation detector according to claim 2, characterized in that: It also includes a first light-shielding sleeve and a second light-shielding sleeve, the first light-shielding sleeve is used to be sleeved on the plasma input tube, and the second light-shielding sleeve is used to be sleeved on the plasma output tube. The first light-shielding sleeve and the second light-shielding sleeve are both provided with two through holes opposite to each other, the first light-emitting end and the first detection end respectively pass through the two through holes of the first light-shielding sleeve and extend into the first light-shielding sleeve, and the second light-emitting end and the second detection end respectively pass through the two through holes of the second light-shielding sleeve and extend into the second light-shielding sleeve.

5. The bilirubin adsorption column saturation detector according to claim 1, characterized in that: The wavelength of the light emitted by the light emitting device is 430nm-490nm.

6. The bilirubin adsorption column saturation detector according to claim 1, characterized in that: The light emitting device includes a laser generator and two optical fibers, one end of each of the two optical fibers is connected to the output end of the laser generator, and the other end of each of the two optical fibers forms the first light emitting end and the second light emitting end.

7. The bilirubin adsorption column saturation detector according to claim 1, characterized in that: The detection device includes a data processor and two detection heads. The two detection heads are signal-connected to the data processor. The two detection heads respectively form a first detection end and a second detection end. The two detection heads can respectively detect the intensity of light passing through the plasma input tube and the plasma output tube and transmit the signal to the data processor. The data processor can calculate the saturation of the bilirubin adsorption column based on the light intensity measured by the two detection heads.

8. The bilirubin adsorption column saturation detector according to claim 7, characterized in that: It also includes multiple indicator lights, and the data processor is in communication with the indicator lights. Different indicator lights are used to indicate different saturations. The data processor controls the corresponding indicator lights to light up according to the saturation of the bilirubin adsorption column.

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