Improved suspension cell culture plate
By setting positioning devices on both sides of the suspension cell culture plate and using suction cups to adsorb on the inner wall of the incubator, the problem of cell detachment caused by shaking of the culture plate is solved, the stable positioning of the culture plate is achieved, and the culture effect is improved.
Patent Information
- Application Number
- CN202422689119.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-05
- Publication Date
- 2025-09-16
- Estimated Expiration
- 2034-11-05
AI Technical Summary
When the suspension cell culture plate is shaken or dropped, the cells are easily detached from the inside of the culture plate, affecting the culture process.
Positioning devices are set on both sides of the culture plate, including groove rods, T-shaped plates, U-shaped rods and suction cups. By rotating the screws, the suction cups are controlled to adsorb on the inner wall of the incubator, limiting the position of the culture plate and preventing shaking and sliding.
It effectively avoids the culture plate from sliding and shaking significantly in the incubator, reduces the leakage of cell fluid, and ensures the stability of the culture.
Smart Images
Figure CN223342722U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell culture plates, in particular to an improved suspension cell culture plate. Background Art
[0002] Suspension cell culture is a non-anchorage-dependent cell culture method that allows cells to grow freely in suspension in liquid culture medium. When culturing cells in suspension, specialized suspension cell culture plates are required. These plates usually have special shapes and surface treatments to adapt to the growth characteristics of suspension cells.
[0003] When using a suspension cell culture plate, after cells are added to the culture plate, they need to be placed in an incubator for culture in a suitable environment. If the table or incubator shakes when the culture plate containing cells is placed on a table, it may cause the culture plate to slide significantly or fall off the table, causing the internal cells to detach from the culture plate, affecting the cell culture process. Utility Model Content
[0004] The purpose of the utility model is to solve the problem that when a culture plate containing cells is placed on a table or inside an incubator, if the table or incubator shakes, the culture plate may slide significantly or fall from the table, causing the internal cells to detach from the culture plate and affecting the cell culture process. An improved suspension cell culture plate is proposed.
[0005] In order to achieve the above-mentioned purpose, the present invention adopts the following technical solutions: an improved suspension cell culture plate, comprising a plate body, a plurality of culture grooves are provided at the top of the plate body, a water injection groove is provided on the outer surface of the plate body, and positioning devices are provided on both sides of the plate body with the aid of auxiliary devices, the auxiliary devices comprising a groove rod, one side of the groove rod is fixedly connected to one side of the plate body, a slot is provided on the outer surface of the groove rod, a T-shaped plate is slidably inserted into the inner wall of the slot, the positioning device comprises a U-shaped rod, the two ends of the U-shaped rod slide on the inner wall of the T-shaped plate, the bottom end of the U-shaped rod is fixedly connected to a rectangular rod, the bottom end of the rectangular rod is provided with two suction cups, the top end of the T-shaped plate is rotatably connected to a screw, and the outer surface of the screw is threadedly connected to the inner wall of the U-shaped rod.
[0006] The effect achieved by the above components is: by setting the suction cup, when using the culture plate, you can first insert the T-shaped plate into the slot at the groove rods on both sides of the plate body, and after placing the cells in the culture groove on the outer surface of the culture plate, when you need to place the culture plate in the incubator, turn the screws at the T-shaped plates on both sides of the plate body to control the U-shaped rod to move downward on the outer surface of the screw, and at the same time, the two ends of the U-shaped rod will slide downward on the inner wall of the T-shaped plate, driving the rectangular rod and the suction cup at the bottom end of the rectangular rod to descend, and adsorb the bottom end of the suction cup on the inner wall of the incubator, thereby limiting the position of the plate body inside the incubator, and avoiding as much as possible the plate body from sliding and shaking significantly inside the incubator when the incubator is shaken, resulting in leakage of cell fluid inside the culture groove.
[0007] Preferably, a convex piece is fixedly connected to one side of the top end of the suction cup, and the convex piece is made of rubber material.
[0008] The effect achieved by the above components is: after the suction cup is adsorbed on the inner wall of the incubator or on the table, when the position of the plate needs to be moved, the rubber protrusion on the top of the suction cup can be pulled to lift the suction cup, and then the screw can be turned to control the U-shaped rod and the rectangular rod to rise so that the suction cup moves away from the adsorption surface.
[0009] Preferably, the top end of the suction cup is fixedly connected to two oblique rods, and one end of the two oblique rods away from the suction cup is fixedly connected to the bottom end of the rectangular rod.
[0010] The effect achieved by the above components is that the side of the connection between the suction cup and the rectangular rod can be reinforced by setting the oblique rod, thereby preventing the bottom end of the suction cup from being subjected to force and causing the connection with the rectangular rod to loosen and break.
[0011] Preferably, a round block is fixedly connected to the top end of the screw, and a plurality of protrusions are fixedly connected to the outer surface of the round block, and the protrusions are distributed in a circular pattern on the outer surface of the round block.
[0012] The effect achieved by the above components is that by holding the protrusion on the outer surface of the round block, the round block can be rotated more conveniently to control the rotation of the screw without slipping.
[0013] Preferably, the auxiliary device further comprises a rectangular plate, a plurality of springs are provided on one side of the rectangular plate, and two ends of the springs are respectively fixedly connected to one side of the rectangular plate and one side of the T-shaped plate.
[0014] The effect achieved by the above components is: when the positioning device is installed on the side of the plate body, first press the rectangular plate to move the rectangular plate toward the T-shaped plate and compress the spring, then insert the T-shaped plate and the rectangular plate horizontally into the slot, push the T-shaped plate to continue moving until the rectangular plate is completely inside the slot, and the position of the T-shaped plate and the rectangular plate inside the slot can be fixed by the thrust of the spring. The positioning device is fixed on one side of the plate body. When removing the positioning device, push the T-shaped plate toward the direction of the slot rod to compress the spring, and then push the T-shaped plate horizontally out of the slot.
[0015] Preferably, oblique grooves are provided at both ends of the inner wall of the slot, and the oblique grooves are located at the edges of the inner wall of the slot.
[0016] The effect achieved by the above components is that the T-shaped plate and the rectangular plate can be more conveniently inserted into the interior of the slot at the inclined groove, thereby improving the convenience when installing the positioning device with the aid of an auxiliary device.
[0017] Preferably, two grooves are provided at one end of the T-shaped plate, and the two grooves are respectively located at the upper and lower sides of the T-shaped plate.
[0018] The above components have the following effects: pinching the two grooves on the outer surface of the T-shaped plate with hands can more conveniently control the T-shaped plate for assembly and disassembly without slipping.
[0019] Preferably, a rectangular piece is fixedly connected to one side of the rectangular plate, and the rectangular piece is made of rubber material.
[0020] The effect achieved by the above components is: by setting a rectangular piece of rubber material, the friction force when the rectangular plate is in contact with the inner wall of the slot when it is inside the slot can be increased, making the rectangular plate less likely to slide inside the slot, and the position of the positioning device on one side of the plate body more stable.
[0021] Compared with the prior art, the advantages and positive effects of the present invention are:
[0022] In the utility model, a positioning device is provided, and the rectangular rod and the suction cup at the bottom end of the rectangular rod are controlled to descend by rotating the screw rod, so that the bottom end of the suction cup is adsorbed on the inner wall of the incubator, thereby limiting the position of the plate body inside the incubator, and preventing as much as possible the plate body from sliding and shaking significantly inside the incubator when the incubator shakes, which may cause leakage of cell fluid inside the culture tank. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;
[0024] Figure 2 This is a schematic diagram of the three-dimensional structure of the plate body of the utility model;
[0025] Figure 3This is a schematic diagram of the three-dimensional structure of the T-shaped plate of the utility model;
[0026] Figure 4 It is a schematic diagram of the three-dimensional structure of the U-shaped rod of the utility model.
[0027] Legend: 1. Plate; 2. Positioning device; 3. Auxiliary device; 4. Culture tank; 5. Water filling tank; 21. U-shaped rod; 22. Screw; 23. Rectangular rod; 24. Suction cup; 25. Lug; 26. Oblique rod; 27. Round block; 28. Protrusion; 31. Slot rod; 32. Slot; 33. T-shaped plate; 34. Spring; 35. Rectangular plate; 36. Oblique groove; 37. Groove; 38. Rectangular piece. DETAILED DESCRIPTION
[0028] Example 1, as Figure 1-4 As shown, an improved suspension cell culture plate comprises a plate body 1, a plurality of culture grooves 4 are provided on the top of the plate body 1, a water injection groove 5 is provided on the outer surface of the plate body 1, and positioning devices 2 are provided on both sides of the plate body 1 with the aid of an auxiliary device 3, the auxiliary device 3 comprises a groove rod 31, one side of the groove rod 31 is fixedly connected to one side of the plate body 1, a slot 32 is provided on the outer surface of the groove rod 31, a T-shaped plate 33 is slidably inserted into the inner wall of the slot 32, the positioning device 2 comprises a U-shaped rod 21, both ends of the U-shaped rod 21 slide on the inner wall of the T-shaped plate 33, the bottom end of the U-shaped rod 21 is fixedly connected to a rectangular rod 23, the bottom end of the rectangular rod 23 is provided with two suction cups 24, the top end of the T-shaped plate 33 is rotatably connected to a screw rod 22, the outer surface of the screw rod 22 is threadedly connected to the inner wall of the U-shaped rod 21, and the screw rod 22 is threadedly connected to the inner wall of the U-shaped rod 21. Place the suction cup 24. When using the culture plate, you can first insert the T-shaped plate 33 into the slot 32 at the groove rod 31 on both sides of the plate body 1. After placing the cells in the culture groove 4 on the outer surface of the culture plate, when you need to place the culture plate inside the incubator, turn the screw 22 at the T-shaped plate 33 on both sides of the plate body 1 to control the U-shaped rod 21 to move downward on the outer surface of the screw 22. At the same time, the two ends of the U-shaped rod 21 will slide downward on the inner wall of the T-shaped plate 33, driving the rectangular rod 23 and the suction cup 24 at the bottom end of the rectangular rod 23 to descend, and adsorb the bottom end of the suction cup 24 on the inner wall of the incubator, thereby limiting the position of the plate body 1 inside the incubator, and avoiding as much as possible the plate body 1 from sliding and shaking significantly inside the incubator when the incubator shakes, resulting in leakage of cell fluid inside the culture groove 4.
[0029] Reference Figure 2-4As shown, in this embodiment: a protrusion 25 is fixedly connected to one side of the top of the suction cup 24, and the protrusion 25 is made of rubber material. After the suction cup 24 is adsorbed on the inner wall of the incubator or on the table, when the position of the plate body 1 needs to be moved, the rubber protrusion 25 on the top of the suction cup 24 can be used to pull one side of the suction cup 24 to lift the suction cup 24, and then the screw 22 is rotated to control the U-shaped rod 21 and the rectangular rod 23 to rise so that the suction cup 24 is away from the adsorption surface. Two inclined rods 26 are fixedly connected to the top of the suction cup 24, and the ends of the two inclined rods 26 away from the suction cup 24 are fixedly connected to the bottom end of the rectangular rod 23. By providing the inclined rods 26, the side edges of the connection between the suction cup 24 and the rectangular rod 23 can be reinforced to avoid as much as possible the force on the bottom end of the suction cup 24 causing the connection with the rectangular rod 23 to loosen and break.
[0030] Reference Figure 2-4 As shown, in this embodiment: the top end of the screw 22 is fixedly connected with a round block 27, and the outer surface of the round block 27 is fixedly connected with a plurality of protrusions 28, which are distributed in a circle on the outer surface of the round block 27. Holding the protrusions 28 on the outer surface of the round block 27 can more conveniently rotate the round block 27 to control the rotation of the screw 22 without slipping.
[0031] Reference Figure 1 、 Figure 2 and Figure 4 As shown, in this embodiment: the auxiliary device 3 also includes a rectangular plate 35, and a plurality of springs 34 are provided on one side of the rectangular plate 35, and the two ends of the spring 34 are fixedly connected to one side of the rectangular plate 35 and one side of the T-shaped plate 33 respectively. When the positioning device 2 is installed on the side of the plate body 1, the rectangular plate 35 is first pressed to move the rectangular plate 35 in the direction of the T-shaped plate 33 and compress the spring 34, and then the T-shaped plate 33 and the rectangular plate 35 are horizontally inserted into the interior of the slot 32, and the T-shaped plate 33 is pushed to continue moving until the rectangular plate 35 is completely in the interior of the slot 32. The thrust of the spring 34 can fix the positions of the T-shaped plate 33 and the rectangular plate 35 in the interior of the slot 32, and the positioning device 2 is fixed to one side of the plate body 1. When removing the positioning device 2, the T-shaped plate 33 is pushed in the direction of the slot rod 31 to compress the spring 34, and then the T-shaped plate 33 is pushed horizontally to disengage from the interior of the slot 32.
[0032] Reference Figure 1 、 Figure 2 and Figure 4The two grooves 37 are respectively located on the upper and lower sides of the T-shaped plate 33, and the two grooves 37 are respectively located on the upper and lower sides of the T-shaped plate 33. By pinching the two grooves 37 on the outer surface of the T-shaped plate 33 with the hands, the T-shaped plate 33 can be more conveniently controlled to be disassembled and assembled without slipping. A rectangular piece 38 is fixedly connected to one side of the rectangular plate 35, and the rectangular piece 38 is made of rubber material. By setting the rectangular piece 38 of rubber material, the friction between the rectangular plate 35 and the inner wall of the slot 32 when it is inside the slot 32 can be increased, so that the rectangular plate 35 is not easy to slide inside the slot 32, and the position fixation of the positioning device 2 on one side of the plate body 1 is more stable.
[0033] Working principle: When using the culture plate, first press the rectangular plate 35 on one side of the T-shaped plate 33 on both sides of the plate body 1 to move the rectangular plate 35 toward the T-shaped plate 33 and compress the spring 34, then insert the T-shaped plate 33 and the rectangular plate 35 into the slot 32 horizontally, push the T-shaped plate 33 to continue moving until the rectangular plate 35 is completely inside the slot 32, and the thrust of the spring 34 can fix the position of the T-shaped plate 33 and the rectangular plate 35 inside the slot 32, fix the positioning device 2 on one side of the plate body 1, and then install the positioning device 2 on the other side of the plate body 1. After the installation is completed, inject liquid into the water injection groove 5 at the top of the plate body 1 to keep the moisture in the environment of the plate body 1, and then inject water into the inside of the plate body 1. Add culture fluid to the culture tank 4, place the plate body 1 inside the incubator, rotate the screw 22 at the T-shaped plates 33 on both sides of the plate body 1, and control the U-shaped rod 21 to move downward on the outer surface of the screw 22. At the same time, the two ends of the U-shaped rod 21 will slide downward on the inner wall of the T-shaped plate 33, driving the rectangular rod 23 and the suction cup 24 at the bottom end of the rectangular rod 23 to descend, and adsorb the bottom end of the suction cup 24 on the inner wall of the incubator to limit the position of the plate body 1 inside the incubator. When the culture is completed and the plate body 1 is taken out, the rubber protrusion 25 at the top of the suction cup 24 can be pulled to lift the suction cup 24, and then the screw 22 is rotated again to control the U-shaped rod 21 and the rectangular rod 23 to rise so that the suction cup 24 is away from the adsorption surface, and then the plate body 1 can be taken away.
[0034] The above description is only a preferred embodiment of the present invention and does not limit the present invention in other forms. Any technician familiar with the profession may use the technical content disclosed above to change or modify it into an equivalent embodiment with equivalent changes and apply it to other fields. However, any simple modification, equivalent change and modification of the above embodiment based on the technical essence of the present invention that does not deviate from the content of the technical solution of the present invention still falls within the protection scope of the technical solution of the present invention. In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
Claims
1. An improved suspension cell culture plate, comprising a plate body (1), characterized in that: The top of the plate body (1) is provided with a plurality of culture grooves (4), the outer surface of the plate body (1) is provided with a water injection groove (5), and both sides of the plate body (1) are provided with positioning devices (2) with the aid of auxiliary devices (3), and the auxiliary devices (3) include a groove rod (31), one side of the groove rod (31) is fixedly connected to one side of the plate body (1), the outer surface of the groove rod (31) is provided with a slot (32), and the inner wall of the slot (32) is slidably inserted The positioning device (2) comprises a U-shaped rod (21), both ends of the U-shaped rod (21) slide on the inner wall of the T-shaped plate (33), the bottom end of the U-shaped rod (21) is fixedly connected to a rectangular rod (23), the bottom end of the rectangular rod (23) is provided with two suction cups (24), the top end of the T-shaped plate (33) is rotatably connected to a screw rod (22), and the outer surface of the screw rod (22) is threadedly connected to the inner wall of the U-shaped rod (21).
2. The improved suspension cell culture plate according to claim 1, characterized in that: A convex piece (25) is fixedly connected to one side of the top end of the suction cup (24), and the convex piece (25) is made of rubber material.
3. The improved suspension cell culture plate according to claim 2, characterized in that: The top end of the suction cup (24) is fixedly connected to two oblique rods (26), and one end of the two oblique rods (26) away from the suction cup (24) is fixedly connected to the bottom end of the rectangular rod (23).
4. The improved suspension cell culture plate according to claim 3, characterized in that: The top end of the screw rod (22) is fixedly connected to a round block (27), and the outer surface of the round block (27) is fixedly connected to a plurality of protrusions (28), and the protrusions (28) are distributed in a circular shape on the outer surface of the round block (27).
5. The improved suspension cell culture plate according to claim 4, characterized in that: The auxiliary device (3) further comprises a rectangular plate (35), one side of which is provided with a plurality of springs (34), and two ends of the springs (34) are respectively fixedly connected to one side of the rectangular plate (35) and one side of the T-shaped plate (33).
6. The improved suspension cell culture plate according to claim 5, characterized in that: Both ends of the inner wall of the slot (32) are provided with oblique grooves (36), and the oblique grooves (36) are located at the inner wall edge of the slot (32).
7. The improved suspension cell culture plate according to claim 6, characterized in that: One end of the T-shaped plate (33) is provided with two grooves (37), and the two grooves (37) are respectively located on the upper and lower sides of the T-shaped plate (33).
8. The improved suspension cell culture plate according to claim 6, characterized in that: A rectangular piece (38) is fixedly connected to one side of the rectangular plate (35), and the rectangular piece (38) is made of rubber material.