Liquid chromatographic column plugging device

Abstract

The utility model discloses a liquid chromatographic column plugging device, and relates to the technical field of liquid chromatographic accessories. The plugging assembly is arranged in the chromatographic column pipe joint, the plugging assembly comprises a fixed plugging piece, an inner sealing assisting piece and an outer sealing assisting piece, and the fixed plugging piece is used for plugging the chromatographic column pipe joint with the minimum size; the fixed plugging piece comprises a plugging block and a plugging head. The first annular plate or the second annular plate is overlaid on the outer side of the plugging block through the clamping strip and the clamping groove, the plugging size of the plugging block is increased, and when the plugging block is screwed into a port of the chromatographic column pipe joint, the annular sealing ring with the outer diameter larger than the inner diameter of a pipeline of the chromatographic column pipe joint can be intercepted; and the annular sealing ring with the outer diameter larger than the inner diameter of the pipeline opening and the plugging head smoothly enter the pipeline opening for plugging, the device can be suitable for plugging work of chromatographic column pipe joints of various types, the application range is wide, and the flexibility is high.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid chromatography accessories, in particular to a liquid chromatography column blocking device. Background Art

[0002] Liquid chromatography is an important chromatographic analysis technique used to separate and detect compounds in samples. Liquid chromatography is a liquid phase separation technique that separates components in a mixture through the distribution behavior between the mobile phase and the stationary phase. The liquid chromatography column is one of the main components used in liquid chromatography analysis. In this process, the liquid chromatography column is specifically used to separate the components in the sample and further quantify and identify them. The liquid chromatography column usually consists of a tube shell, filler and column port. In order to prevent the loss of filler and solvent leakage, the column port needs to be sealed.

[0003] After searching, a liquid chromatography column plugging device with publication number CN217887062U was found, which includes a connector and a plug of the chromatography column. There are two grooves on the inner cavity wall of the connector, and the plug has two plugs. The sealing part of the plug is made of elastic material. The plugs of the plug are combined with the grooves of the connector to seal the chromatography column, thereby achieving the effect of sealing the chromatography column, preventing the volatilization of organic solvents, and conveniently installing and removing the plug.

[0004] In this patent disclosure, the sizes of the plug and the sealing portion are fixed, so only one size of liquid chromatography column port can be sealed. However, the ports of liquid chromatography columns from different manufacturers, different specifications, different lengths, and different types have different sizes. The sealing device cannot flexibly change the sealing size according to the size of the liquid chromatography column port, and has a narrow scope of application and low flexibility. Utility Model Content

[0005] The purpose of the utility model is to provide a liquid chromatography column plugging device, which solves the problem that the existing plugging device cannot flexibly change the plugging size according to the liquid chromatography column port size, has a narrow application range and low flexibility.

[0006] The utility model solves the above technical problems through the following technical solutions, and the utility model includes:

[0007] Chromatographic column tube connector;

[0008] A plugging assembly is provided inside the chromatographic column pipe joint, the plugging assembly comprising a solid plugging piece, an inner auxiliary sealing piece and an outer auxiliary sealing piece, the solid plugging piece being used to plug the chromatographic column pipe joint of the smallest size;

[0009] The fixed sealing member includes a sealing block and a sealing head, and the sealing head is fixed below the sealing block;

[0010] The inner auxiliary seal is arranged below the blocking block, and is used to increase the size of the blocking head for blocking. The outer auxiliary seal is arranged outside the blocking block, and is used to increase the blocking range of the blocking block.

[0011] Preferably, an inner groove is provided below the blocking block, and the inner auxiliary seal comprises two annular sealing rings sliding inside the inner groove, and a plurality of springs are provided above the two annular sealing rings.

[0012] Preferably, two first traction grooves are provided on the outer surface of the sealing block, and the external auxiliary seal includes a first annular plate, which slides on the outside of the sealing block through two traction feet, and two second traction grooves are provided on the outer surface of the first annular plate, and a second annular plate slides on the outside of the first annular plate through two pins.

[0013] Preferably, two clamping grooves are provided on the outer surface of the blocking block and the outer surface of the first annular plate, and two clamping strips are fixed on the inner surface of the first annular plate and the inner surface of the second annular plate.

[0014] Preferably, a force-applying plate is fixed above the blocking block.

[0015] Preferably, a first thread groove is formed on the inner surface of the chromatographic column pipe joint, and a second thread groove is formed on the outer surface of the blocking block, the outer surface of the first annular plate, and the outer surface of the second annular plate.

[0016] Compared with the prior art, the beneficial effects of the present invention are:

[0017] The utility model superimposes the first annular plate or the second annular plate on the outside of the sealing block by means of the provided clamping strips and the clamping grooves, thereby increasing the sealing size of the sealing block. When the sealing block is screwed into the port of the chromatographic column pipe joint, the annular sealing ring with an outer diameter larger than the inner diameter of the pipe of the chromatographic column pipe joint will be intercepted, and as the sealing block moves downward into the inner groove, the spring is squeezed, and the annular sealing ring with an outer diameter larger than the inner diameter of the pipe opening and the sealing head smoothly enter the pipe opening for sealing. The utility model can be applied to various types of chromatographic column pipe joints for sealing work, and has a wide range of applications and high flexibility. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the main structure of the utility model;

[0019] Figure 2 It is a cross-sectional view of the utility model;

[0020] Figure 3 This is a disassembled internal cross-sectional view of the sealing component in the present invention.

[0021] The numbers in the figure represent:

[0022] 1. Chromatographic column pipe joint; 2. Sealing assembly; 21. Sealing block; 22. Sealing head; 23. Inner groove; 24. Annular sealing ring; 25. Spring; 26. First traction groove; 27. First annular plate; 28. Second traction groove; 29. ​​Second annular plate; 210. Clamping groove; 211. Clamping strip; 3. Force plate; 4. First thread groove; 5. Second thread groove. DETAILED DESCRIPTION

[0023] The above and other technical features and advantages of the present invention are described in more detail below with reference to the accompanying drawings.

[0024] This embodiment provides a technical solution: a liquid chromatography column plugging device, such as Figure 1 As shown, it includes a chromatographic column pipe joint 1 and a sealing component 2. The size of the port of the chromatographic column pipe joint 1 has various sizes due to the different sizes of the chromatographic column itself. The sealing component 2 is arranged inside the chromatographic column pipe joint 1. The sealing component 2 includes a solid sealing part, an internal auxiliary sealing part and an external auxiliary sealing part. The solid sealing part is used to seal the chromatographic column pipe joint 1 of the smallest size. Through the internal auxiliary sealing part and the external auxiliary sealing part, the solid sealing part can be adapted to chromatographic column pipe joints 1 of different sizes, thereby improving the applicability and flexibility of the sealing component 2.

[0025] like Figure 2-3 As shown, the solid sealing part includes a sealing block 21 and a sealing head 22. The sealing head 22 is fixed below the sealing block 21. The sizes of the sealing block 21 and the sealing head 22 are customized according to the size of the smaller chromatographic column pipe joint 1. When used on a larger chromatographic column pipe joint 1 in the future, the size can be increased by relying on the internal auxiliary seal and the external auxiliary seal to achieve sealing and fitting. A force plate 3 is fixed above the sealing block 21 to facilitate the application of force and rotation of the sealing block 21.

[0026] like Figure 2-3 As shown, the internal auxiliary seal is arranged below the sealing block 21, and the internal auxiliary seal is used to increase the size of the sealing head 22 for sealing. An inner groove 23 is provided below the sealing block 21, and the inner groove 23 is provided on the outer ring of the sealing head 22. The internal auxiliary seal includes two annular sealing rings 24 that slide inside the inner groove 23. Only two annular sealing rings 24 are shown in the figure. In actual conditions, several groups of annular sealing rings 24 can be set according to the size model of the chromatographic column pipe joint 1. A plurality of springs 25 are provided above the two annular sealing rings 24. When the springs 25 are not squeezed by pressure, most of the annular sealing rings 24 are in a state of extending to the outside of the inner groove 23, and the bottom of the annular sealing ring 24 is level with the bottom of the sealing head 22. When the annular sealing ring 24 is squeezed, the spring 25 is compressed and slides into the inner groove 23.

[0027] like Figure 2-3As shown, the external seal is arranged on the outside of the blocking block 21, and the external seal is used to increase the blocking range of the blocking block 21. The outer surface of the blocking block 21 is provided with two first traction grooves 26, and the external seal includes a first annular plate 27. The first annular plate 27 slides on the outside of the blocking block 21 through two traction feet, and the two traction feet slide respectively inside the two first traction grooves 26. The limit between the traction feet and the first traction groove 26 plays a role in guiding the sliding of the first annular plate 27. The outer surface of the first annular plate 27 is provided with two second traction grooves 28. The second traction groove 28 and the first traction groove 26 have the same size. The outside of the first annular plate 27 is slid with a second annular plate 29 through two pins. The two pins slide inside the two second traction grooves 28 respectively, and the limit between the pins and the second traction grooves 28 serves to guide the sliding of the second annular plate 29. Like the annular sealing ring 24, the number of the first annular plate 27 and the second annular plate 29 can be set in several groups according to the size model of the chromatographic column pipe connector 1, and each annular plate (i.e., the first annular plate 27 or the second annular plate 29) corresponds to an annular sealing ring 24 for use in combination. For example, when the pipe size of the chromatographic column pipe connector 1 requires the sealing head 22 to be superimposed with an annular sealing ring 24 for sealing, the sealing block 21 needs to be superimposed with an annular plate (i.e., the first annular plate 27 or the second annular plate 29) for use.

[0028] like Figure 2-3 As shown, the outer surface of the blocking block 21 and the outer surface of the first annular plate 27 are both provided with two card grooves 210, and the inner surface of the first annular plate 27 and the inner surface of the second annular plate 29 are both fixed with two card strips 211, the inner surface of the chromatographic column pipe joint 1 is provided with a first thread groove 4, the outer surface of the blocking block 21, the outer surface of the first annular plate 27 and the outer surface of the second annular plate 29 are all provided with a second thread groove 5, the card strip 211 is made of elastic material, such as rubber, and the card strip 211 is inserted into the card groove 210 to limit the position of the first annular plate 27 or the second annular plate 29, so that the first annular plate 27 or the second annular plate 29 can be stably located outside the blocking block 21, preventing the blocking block 21 from sliding out of the chromatographic column pipe joint 1 from the middle when the first annular plate 27 or the second annular plate 29 is spirally screwed to the inner side of the chromatographic column pipe joint 1.

[0029] When in use, according to the size of the port of the chromatographic column pipe connector 1, it is selected whether to move the first annular plate 27 or the second annular plate 29 to the outside of the blocking block 21 to increase the size of the blocking block 21 to match the size of the port of the chromatographic column pipe connector 1 for blocking. If the first annular plate 27 is to be superimposed on the outside of the blocking block 21, it is only necessary to push the first annular plate 27 down until the two clips 211 on the inner side of the first annular plate 27 are snapped into the clip grooves 210 on the outer side of the blocking block 21, so that the first annular plate 27 can be fixedly superimposed on the outer side of the blocking block 21. Similarly, the second annular plate 27 can be fixedly superimposed on the outer side of the blocking block 21. The shaped plate 29 is also overlapped on the outside of the first annular plate 27 through the clamping strip 211 and the clamping groove 210 on its inner side. The overlapping can be released by pushing the clamping strip 211 on the first annular plate 27 or the second annular plate 29 out of the corresponding clamping groove 210. After the overlapping is completed, the blocking block 21 is placed into the port of the chromatographic column pipe connector 1, and the blocking block 21, the first annular plate 27 and the second annular plate 29 are rotated by the force plate 3, and the blocking block 21 is fixedly installed in the port of the chromatographic column pipe connector 1 by screwing the first thread groove 4 and the second thread groove 5 to achieve sealing.

[0030] When the blocking block 21 is screwed into the port of the chromatographic column pipe joint 1, the annular sealing ring 24 outside the inner diameter of the pipe opening will be intercepted according to the size of the pipe opening of the chromatographic column pipe joint 1, and as the blocking block 21 moves downward, the intercepted annular sealing ring 24 moves up into the inner groove 23 and squeezes the spring 25, and the annular sealing ring 24 outside the inner diameter of the pipe opening and the blocking head 22 smoothly enter the pipe opening for blocking. It can be applicable to various models of chromatographic column pipe joints 1 for blocking work.

[0031] The above are only preferred embodiments of the present invention and are intended to be illustrative rather than restrictive. Those skilled in the art will appreciate that many changes, modifications, and even equivalents may be made to the embodiments within the spirit and scope of the claims, all of which fall within the scope of protection of the present invention.

Claims

1. A liquid chromatography column plugging device, characterized in that: include: Chromatographic column tube connector (1); A plugging component (2), the plugging component (2) being arranged inside the chromatographic column pipe joint (1), the plugging component (2) comprising a solid plugging piece, an inner auxiliary sealing piece and an outer auxiliary sealing piece, the solid plugging piece being used to plug the chromatographic column pipe joint (1) of the smallest size; The fixed sealing member comprises a sealing block (21) and a sealing head (22), wherein the sealing head (22) is fixed below the sealing block (21); The inner auxiliary seal is arranged below the blocking block (21), and is used to increase the size of the blocking head (22) for blocking. The outer auxiliary seal is arranged outside the blocking block (21), and is used to increase the blocking range of the blocking block (21).

2. The liquid chromatography column plugging device according to claim 1, characterized in that: An inner groove (23) is provided below the blocking block (21), and the inner auxiliary seal comprises two annular sealing rings (24) sliding inside the inner groove (23), and a plurality of springs (25) are provided above the two annular sealing rings (24).

3. The liquid chromatography column plugging device according to claim 1, wherein: The outer surface of the blocking block (21) is provided with two first traction grooves (26); the external auxiliary sealing member comprises a first annular plate (27); the first annular plate (27) slides on the outside of the blocking block (21) via two traction legs; the outer surface of the first annular plate (27) is provided with two second traction grooves (28); a second annular plate (29) slides on the outside of the first annular plate (27) via two pins.

4. The liquid chromatography column blocking device according to claim 3, wherein: The outer surface of the blocking block (21) and the outer surface of the first annular plate (27) are both provided with two clamping grooves (210), and the inner surface of the first annular plate (27) and the inner surface of the second annular plate (29) are both fixed with two clamping strips (211).

5. The liquid chromatography column blocking device according to claim 1, wherein: A force application plate (3) is fixed above the blocking block (21).

6. The liquid chromatography column blocking device according to claim 3, wherein: The inner surface of the chromatographic column pipe joint (1) is provided with a first thread groove (4), and the outer surface of the blocking block (21), the outer surface of the first annular plate (27), and the outer surface of the second annular plate (29) are all provided with a second thread groove (5).

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