Medicine taking device for medicine production

Abstract

The utility model discloses a medicine taking device for medicine production, which comprises a sampling mechanism communicated with a sampling port on a reaction kettle, the sampling mechanism comprises a fixed seat, a pushing piece arranged on the fixed seat and a sampling tube arranged on the pushing piece, and the pushing piece is used for pushing the sampling tube to enter and exit from the sampling port. The sampling tube comprises a tube body and a rubber head arranged at one end of the tube body, and an extrusion part for extruding the rubber head is arranged on the tube body. According to the raw material sampling device disclosed by the invention, raw material medicines in the reaction kettle are sampled by arranging the pushing piece, the sampling pipe and the extruding piece, a worker does not need to hold a long-handle sampler by hand for sampling, and only simple operation is needed, so that the problem that the raw material medicines are inconvenient to sample in the reaction kettle at present is effectively solved.

Description

Technical Field

[0001] The utility model belongs to the field of medicine sampling equipment, in particular to a medicine sampling device for medicine production. Background Art

[0002] In the production process of raw materials, the most common production equipment is the reactor, but it is often necessary to take samples and test them inside the reactor to judge the degree of reaction based on the test results.

[0003] In the prior art, sampling is generally performed by opening the sampling cover of the reactor and inserting a long-handled sampler to take samples. However, due to the long length of the sampler, it is not easy to control, and sometimes it is necessary to sample APIs at different depths, which makes it extremely inconvenient to take APIs. At the same time, during the sampling process, the inside and outside of the reactor are connected for a long time, which makes it easy for the APIs to be contaminated.

[0004] The existing public document CN201710235512.X proposes to extract samples through an air pump and a sampling tube inserted into the reactor, but it is not possible to perform sampling on the raw materials at different depths in the reactor, and there is still the problem of inconvenient sampling.

[0005] The existing public document CN202111094482.8 proposes that sampling be completed by installing a sampling tube with multiple sampling holes at different heights in the reactor, and cooperating with a lifting tube that can be raised and lowered to sample the sampling holes separately. However, this leads to the same problem as the current long-handled sampler. Due to its long length, it is inconvenient for staff to operate, and there is also the problem of inconvenient sampling. Utility Model Content

[0006] The technical problem to be solved by the utility model is to provide a medicine taking device for pharmaceutical production to solve the problem of inconvenience in sampling raw medicines in a reaction kettle.

[0007] In order to solve the above problems, the present invention adopts the following technical solutions:

[0008] A drug dispensing device for pharmaceutical production includes a sampling mechanism connected to a sampling port on a reactor. The sampling mechanism includes a fixed seat, a pushing member arranged on the fixed seat, and a sampling tube arranged on the pushing member. The pushing member is used to push the sampling tube in and out of the sampling port. The sampling tube includes a tube body and a rubber head arranged at one end of the tube body. The pushing member is provided with an extrusion member for extruding the rubber head.

[0009] Furthermore, a compression tube is provided outside the tube body, one end of the compression tube is tightly connected to the fixing seat, the other end of the compression tube is tightly connected to the outer wall of the tube body, and the rubber head is located outside the compression tube.

[0010] Furthermore, a sample receiving port is provided on one side of the fixing seat, an air release valve is provided on the sample receiving port, and an air filling valve is provided on the sample receiving port.

[0011] Further, a sterile box communicating with the sample receiving port is provided on the fixed seat. A switch door for closing the sample receiving port is provided in the sterile box. A sampling door is opened on the sterile box, and a sterilization device for sterilizing the inside thereof is provided on the sterile box.

[0012] Further, the sampling port is opened upward, and a liquid removing ring is provided on the sampling port.

[0013] Further, the pushing member includes a linear motor.

[0014] Further, the squeezing member includes an electric push rod and a U-shaped squeezing seat. The squeezing seat is arranged on the moving block in the pushing member. The electric push rod is arranged in the squeezing seat. The rubber head is arranged in the squeezing seat and on one side of the electric push rod. The tube body is fixedly connected to the moving block in the pushing member.

[0015] The remarkable beneficial effects achieved by the present utility model are as follows:

[0016] 1. In this application, the pushing member, the sampling tube and the squeezing member are provided to sample the active pharmaceutical ingredient in the reactor. There is no need for the staff to hold a long-handled sampler for sampling, and only simple operations are required, effectively solving the problem of inconvenient sampling of the active pharmaceutical ingredient in the reactor at present.

[0017] 2. The setting of the compression tube and the sample receiving port can form a closed space communicating with the inside of the reactor during the sampling process, avoiding the contact between the active pharmaceutical ingredient and the outside world during the sampling process.

[0018] 3. The setting of the sterile box can form an isolation space, further avoiding the contact between the active pharmaceutical ingredient in the reactor and the outside world.

[0019] 4. The setting of the inflation valve and the deflation valve can keep the air pressure stable during the sampling process.

[0020] 5. The setting of the liquid removing ring can scrape the medicine remaining on the outer wall of the tube body, avoiding the dripping of the remaining medicine on the outer wall of the tube body. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Attached Figure 1 is the front view structural schematic diagram of the working state of the present utility model;

[0022] Attached Figure 2 is the enlarged structural schematic diagram at A in the present utility model Figure 1 ;

[0023] Attached Figure 3 is the enlarged structural schematic diagram at B in the present utility model Figure 1 ;

[0024] Attached Figure 4 is the right view structural schematic diagram of the sterile box in the present utility model;

[0025] Attached Figure 5 is a schematic cross-sectional view of the sampling port structure in the present utility model.

[0026] In the attached drawings, 1 is a fixed seat; 2 is a pusher; 3 is a rubber head; 4 is a tube body; 5 is a compression tube; 6 is a sample receiving port; 7 is an inflation valve; 8 is a deflation valve; 9 is a sterile box; 10 is a switch door; 11 is a sampling door; 12 is a sterilization device; 13 is a liquid removal ring; 14 is an electric push rod; 15 is a pressing seat; 16 is a sampling port; 17 is a reaction kettle. Specific embodiments

[0027] Next, the technical solutions in the embodiments of the present application will be clearly and completely described in conjunction with the attached drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. The description of at least one exemplary embodiment below is actually only illustrative and in no way a limitation to the present application and its application or use. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present application.

[0028] Embodiment 1

[0029] As Figure 1 , Figure 2 , Figure 3 and Figure 5 shown, a medicine taking device for pharmaceutical production includes a sampling mechanism communicated with the sampling port 16 on the reaction kettle 17. The sampling mechanism includes a fixed seat 1 fixedly installed on the reaction kettle 17, a pusher 2 installed on the fixed seat 1, and a sampling tube installed on the pusher 2. The fixed seat 1 is communicated with the sampling port 16 on the reaction kettle 17. The pusher 2 is used to push the sampling tube into or out of the interior of the reaction kettle 17 from the sampling port 16. The sampling tube includes a tube body 4 and a rubber head 3 installed at one end of the tube body 4. An extrusion member for extruding the rubber head 3 is installed on the pusher 2.

[0030] In this embodiment, the opening of the sampling port 16 is upwardly opened. The pusher 2 is vertically installed on the reaction kettle 17. The pusher 2 is a linear motor. The extrusion member includes an electric push rod 14 and a U-shaped pressing seat 15. One end of the pressing seat 15 is fixedly connected to the moving block in the linear motor. The electric push rod 14 is horizontally installed in the pressing seat 15. The rubber head 3 is located in the pressing seat 15 and on one side of the telescopic end of the electric push rod 14. The tube body 4 is fixedly connected to the moving block in the linear motor through a clamp.

[0031] Working principle: when it is necessary to sample the raw materials in the reactor 17, first open the sampling port 16, operate the extrusion part to squeeze the rubber head 3, and then operate the pushing part 2 to drive the tube body 4 to move downward. After the tube mouth of the tube body 4 reaches the desired sampling depth, operate the extrusion part to no longer squeeze the rubber head 3. At this time, the tube body 4 begins to absorb the raw materials, and then the pushing part 2 drives the tube body 4 to leave the reactor 17 from the sampling port 16. The staff then closes the sampling port 16, and then places the sample container under the tube body 4, and operates the extrusion part to squeeze the rubber head 3 again to squeeze the sample into the sample container.

[0032] In combination with the above, in this application, the raw materials in the reactor 17 are sampled by setting the pushing part 2, the sampling tube and the extrusion part. There is no need for the staff to hold a long-handled sampler for sampling. Only simple operations are required, which effectively solves the current problem of inconvenience in sampling raw materials in the reactor 17.

[0033] Example 2

[0034] like Figure 1 、 Figure 2 and Figure 3 As shown, the structure of this embodiment is roughly the same as that of Example 1. This embodiment is further optimized on the basis of Example 2. In order to prevent the raw materials in the reaction kettle 17 from contacting with the external environment, a deformable compression tube 5 is provided on the outside of the tube body 4 in this embodiment. One end of the compression tube 5 is tightly connected to the upper end of the fixing seat 1, and the other end of the compression tube 5 is tightly connected to the outer wall of the tube body 4. The rubber head 3 is located on the outside of the compression tube 5.

[0035] When the sampling port 16 is opened, the space where the tube body 4 is located and the space inside the reactor 17 are sealed by the arrangement of the compression tube 5, thereby preventing the API inside the reactor 17 from coming into contact with the outside world.

[0036] To collect the sample after sampling, a sample port 6 is provided on one side of the fixing base 1. The sample port 6 is equipped with a vent valve 8 and an inflation valve 7. These vent valves 8 and inflation valves 7 maintain a stable pressure within the reactor 17 and the compression tube 5, preventing the operation of the compression tube 5 from causing large fluctuations in the pressure within the reactor 17. (The inflation valve 7 is used to connect to the inflation source.)

[0037] In this embodiment, the fixing seat 1 is a three-way pipe, and the upper and lower ends of the fixing seat 1 are respectively sealed with the compression tube 5 and the reactor 17. The sample port 6 is an opening on one side of the fixing seat 1. In this embodiment, a door is installed on the sample port 6 for opening and closing.

[0038] This embodiment is combined with the content of Example 1. The working principle is as follows: before sampling the raw material drug, the air source is inflated through the inflation valve 7 to make the air pressure in the compression tube 5 consistent with the air pressure in the reactor 17, and then the sampling port 16 is opened. When the pushing member 2 drives the tube body 4 toward the reactor 17, the compression tube 5 is compressed, and the air release valve 8 is released to keep the air pressure stable. After the sampling is completed, the compression tube 5 rises back under the action of the pushing member 2, and the air source is inflated through the inflation valve 7 to keep the air pressure stable. After the sampling tube leaves the reactor 17, the sampling port 16 is closed, and the air release valve 8 is released to make the air pressure in the compression tube 5 consistent with the external air pressure. The staff then opens the door on the sampling port 6 and uses a sampling container to collect the sample.

[0039] Example 3

[0040] like Figure 1-Figure 5 As shown, the structure of this embodiment is roughly the same as that of Example 2. This embodiment is further optimized on the basis of Example 2. In order to further prevent the API in the reactor 17 from coming into contact with the outside world, a sterile box 9 connected to the sample port 6 is installed on the fixing base 1 in this embodiment. A switch door 10 for closing the sample port 6 is installed in the sterile box 9. A sampling door 11 is opened on the sterile box 9. A sterilizing device 12 for sterilizing the interior of the sterile box 9 is installed.

[0041] An isolated sterilization space is formed by installing the sterilization box 9. The sterilization box is sterilized before and after sampling, which can effectively prevent the raw materials in the reactor 17 from coming into contact with the external environment.

[0042] At the same time, since it is sometimes necessary to sample raw materials at different depths, the sampling tube will have residual drugs on the outer wall when it leaves the sampling port 16. In order to prevent the sampling tube from leaving the sampling port 16, after the sampling port 16 is closed, the residual drugs on the outer wall of the sampling tube will drip onto the closed door of the sampling port 16. A liquid removal ring 13 coaxial with the tube body 4 is installed on the sampling port 16. The liquid removal ring 13 is set to scrape off the residual drugs on the outer wall of the tube body 4 when the tube leaves the tube body 4.

[0043] In this embodiment, the sterile box 9 is a sterile glove box.

[0044] In combination with Example 1 and Example 2, the working principle of this embodiment is that the staff first places the sampling container into the sterile box 9, then opens the sterilization device 12 to sterilize the sterile box 9, opens the switch door 10 at the sampling port 16 and the closing door at the sampling port 16, operates the extrusion part and the pushing part 2 to perform sampling, and when the sampling tube leaves the reactor 17, the liquid removing ring 13 scrapes off the residual medicine on the outer wall of the tube body 4, and closes the sampling port 16 after the sampling is completed. The staff opens the switch door 10 on the sample receiving port 6 to sample the sample in the sampling tube and closes the switch door 10 after sampling, and then opens the sampling door 11 to take out the sample container, and finally sterilizes the sterile box 9 again.

[0045] In combination with the above embodiments, the present application arranges a fixed seat 1, a pushing member, an extruding member, a sampling tube and a sterile box 9. During the sampling process of the raw material medicine in the reactor 17, there is no need to manually hold a long-handled sampler for sampling. It only needs to be collected after the sampling is completed. At the same time, the raw material medicine in the reactor 17 is avoided from contacting the outside world. While effectively solving the current inconvenience of sampling the raw material medicine in the reactor 17, the high-quality production of the raw material medicine is guaranteed.

[0046] It should be noted that, in the above embodiment, the sterilization device 12 is an ultraviolet lamp installed in a sterilization box.

Claims

1. A medicine dispensing device for pharmaceutical production, characterized by: It includes a sampling mechanism connected to the sampling port (16) on the reactor (17). The sampling mechanism includes a fixed seat (1), a pushing member (2) provided on the fixed seat (1), and a sampling tube provided on the pushing member (2). The pushing member (2) is used to push the sampling tube in and out of the sampling port (16). The sampling tube includes a tube body (4) and a rubber head (3) provided at one end of the tube body (4). An extrusion member for extruding the rubber head (3) is provided on the pushing member (2).

2. A drug dispensing device for pharmaceutical production according to claim 1, characterized in that: A compression tube (5) is sleeved outside the tube body (4). One end of the compression tube (5) is hermetically connected to the fixed seat (1), and the other end of the compression tube (5) is hermetically connected to the outer wall of the tube body (4). The rubber head (3) is located outside the compression tube (5).

3. The drug dispensing device for pharmaceutical production according to claim 1, characterized in that: A sample receiving port (6) is opened on one side of the fixed seat (1). An air release valve (8) is provided on the sample receiving port (6), and an air filling valve (7) is provided on the sample receiving port (6).

4. A drug dispensing device for pharmaceutical production according to claim 3, characterized in that: A sterile box (9) communicating with the sample receiving port (6) is provided on the fixed seat (1). A switch door (10) for closing the sample receiving port (6) is provided inside the sterile box (9). A sampling door (11) is opened on the sterile box (9), and a sterilization device (12) for sterilizing the inside thereof is provided on the sterile box (9).

5. The drug dispensing device for pharmaceutical production according to claim 1, characterized in that: The sampling port (16) is opened upward, and a liquid removal ring (13) is provided on the sampling port (16).

6. The drug dispensing device for pharmaceutical production according to claim 1, characterized in that: The pushing member (2) is a linear motor.

7. The drug dispensing device for pharmaceutical production according to claim 1, characterized in that: The extrusion member includes an electric push rod (14) and a U-shaped extrusion seat (15). The extrusion seat (15) is provided on the moving block in the pushing member (2). The electric push rod (14) is provided inside the extrusion seat (15). The rubber head (3) is provided inside the extrusion seat (15) and is located on one side of the electric push rod (14). The tube body (4) is fixedly connected to the moving block in the pushing member (2).

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