Dropper for brain slice rinsing and liquid changing

Abstract

The utility model discloses a dropper for brain slice rinsing and liquid changing, which comprises a dropper body, a filtering device is fixedly arranged below the dropper body, the filtering device comprises a filtering ring fixedly arranged at one end of the dropper body, a plurality of filtering holes are uniformly formed in the surface of the filtering ring, and a bag body is fixedly arranged above the dropper body. A clamping device is fixedly arranged on the surface of the dropper body, a reset device is fixedly arranged on the surface of the dropper body, through mutual cooperation of the structures, the purpose that brain slices can be isolated and only liquid is sucked in the liquid changing process is achieved, meanwhile, the use force of people for using the dropper can be reduced, and the dropper is more convenient and labor-saving.

Description

Technical Field

[0001] The utility model relates to the technical field of brain slice liquid replacement, in particular to a dropper used for rinsing and liquid replacement of brain slices. Background Art

[0002] Processing and analysis of brain slices is an important step in laboratory and biomedical research.

[0003] Brain slices are usually prepared using a microtome or a cryostat, and the thickness of the slices usually ranges from 30 μm to 400 μm, depending on the experimental requirements.

[0004] Sections can be mounted on slides and treated with a chemical fixative, such as formalin, to preserve tissue architecture and cellular morphology.

[0005] In the laboratory, when testing brain slices, it is often necessary to first add an extract to the brain slices. Currently, when adding, a dropper is generally used to draw the extract from the bottle and then add it to the test container. The brain slice solution in the six-well plate needs to be replaced regularly. When the traditional dropper is used to change the liquid, the brain slices are easily sucked out together with the liquid, and the brain slices cannot be isolated. Therefore, in order to solve the above problem, a dropper for rinsing and changing the liquid of brain slices is proposed, so as to meet the purpose of isolating the brain slices and only drawing the liquid during the liquid change process. Utility Model Content

[0006] The purpose of the utility model is to provide a dropper for rinsing and exchanging liquid for brain slices, so as to solve the problems raised in the above background technology.

[0007] To achieve the above-mentioned object, the utility model provides the following technical solution: a dropper for rinsing and exchanging fluid for brain slices, comprising a dropper body, a filter device fixedly provided below the dropper body, a capsule fixedly provided above the dropper body, a clamping device fixedly provided on the surface of the dropper body, and a reset device fixedly provided on the surface of the dropper body;

[0008] The filtering device comprises a filtering ring fixedly mounted on one end of the dropper body, and a plurality of filtering holes are evenly opened on the surface of the filtering ring.

[0009] Furthermore, the filter ring is made of a soft rubber material, so that the filter ring can be deformed during use to contact and seal with the bottom of the six-well plate, so that the brain slices are isolated during the suction process and only liquid can pass through.

[0010] Furthermore, the clamping device includes a clamping ring fixedly mounted on the surface of the dropper body, clamping grooves are fixedly provided on both sides of the clamping ring, a clamping plate is provided in the clamping groove, the clamping plate and the clamping groove are movably connected through an axis, a clamping block is fixedly provided at one end of the clamping plate, an arc groove is provided on one side of the clamping block, and a clamping pressure plate is fixedly provided on the surface of the clamping plate, thereby preventing people from getting tired when pinching the capsule for a long time to wash the liquid during use, resulting in liquid leakage during the absorption process, and increasing the convenience of using the dropper.

[0011] Furthermore, the arc-shaped groove on the surface of the clamping block is adapted to the size of the capsule, so that the capsule can be used to absorb liquid by pinching the middle position of the dropper body.

[0012] Furthermore, the reset device includes a reset ring fixedly mounted on the surface of the dropper body, and a reset spring is symmetrically provided on the side of the reset ring. One end of the reset spring is fixedly connected to the reset ring, and the other end of the reset spring is fixedly connected to one side of the clamping plate, so that the clamping device can be reset by the reset spring after each use is completed, so that the capsule can be restored to perform the next liquid aspiration work.

[0013] Compared with the prior art, the beneficial effects of the present invention are:

[0014] (1) In order to isolate the brain slices during the pipetting process and prevent the brain slices and liquid from being sucked out together, a filter device is fixed under the pipette body;

[0015] During use, the dropper body is inserted into a brain slice container such as a six-well plate, so that the filter ring contacts the bottom of the container. Since the filter ring is made of soft materials such as rubber, the filter ring can produce a certain deformation. When the filter ring contacts the bottom of the container, the filter ring isolates the dripper position of the dropper body, so that a space is formed between the dripper and the filter ring. The liquid in the container flows to the dripper position through the filter hole, so that the dropper body absorbs the liquid, while the brain slices are blocked to the outside by the filter ring and separated from the dripper, ensuring that only the liquid is absorbed during the washing process, and the brain slices are not absorbed. In addition, since the filter ring is made of soft materials such as rubber, the dropper body can be applied to more angles, thereby absorbing the liquid at various angles.

[0016] (2) When using a traditional dropper, people hold the capsule in their hands and press the capsule to use the dropper. Long-term pinching and releasing can easily cause hand soreness and is laborious, affecting the efficiency of using the dropper. Therefore, a clamping device is provided on the surface of the dropper body, and a reset device is provided on the surface of the dropper body, so that the dropper can be used in the middle of the dropper body, reducing the force people use to use the dropper, and making it more convenient and labor-saving.

[0017] When in use, by holding the clamping plate in position, when the filtering device at one end of the dropper body is extended into the container, the clamping plate is pressed to make the clamping plate move under force, and one end of the clamping plate is adjusted in angle by the axis in the clamping groove. The adjustment of the clamping plate drives the clamping block at one end to move, so that the clamping block contacts the capsule and applies pressure to the capsule, causing the capsule to deform and absorb the liquid in the container. When the liquid needs to be discharged and used next time, it is only necessary to cancel the pressure on the clamping plate, so that the reset spring applies an outward thrust to the clamping plate through its own elastic restoring force, so that the clamping plate drives the clamping block to separate from the capsule, so that the capsule recovers and is convenient for the next washing work. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is one of the structural schematic diagrams of a dropper for rinsing and changing fluid for brain slices proposed in the utility model;

[0019] Figure 2 This is the second structural schematic diagram of a dropper for rinsing and exchanging fluid for brain slices proposed by the present invention.

[0020] In the figure: 1. dropper body; 2. filter device; 3. capsule; 4. clamping device; 5. reset device; 201. filter ring; 202. filter hole; 401. clamping ring; 402. clamping groove; 403. clamping plate; 404. clamping block; 405. clamping pressure plate; 501. reset ring; 502. reset spring. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0022] Example 1:

[0023] See also Figure 1-2The utility model provides a technical solution: a dropper for rinsing and changing liquid for brain slices, comprising a dropper body 1, a filter device 2 fixedly installed under the dropper body 1, the filter device 2 comprising a filter ring 201 fixedly installed at one end of the dropper body 1, the filter ring 201 is made of soft rubber material, so that the filter ring 201 can be deformed during use and contact and seal with the bottom of the six-well plate, so that the brain slices can be isolated during the suction process and only liquid can pass through, a plurality of filter holes 202 are evenly opened on the surface of the filter ring 201, a capsule 3 is fixedly installed above the dropper body 1, a clamping device 4 is fixedly installed on the surface of the dropper body 1, the clamping device 4 comprises a clamping ring 401 fixedly installed on the surface of the dropper body 1, clamping grooves 402 are fixedly installed on both sides of the clamping ring 401, a clamping plate 403 is installed in the clamping groove 402, the clamping plate 403 is movably connected to the clamping groove 402 through an axis, and one end of the clamping plate 403 is fixedly mounted with a clamping plate The clamping plate 403 is fixedly mounted with a clamping pressure plate 405, thereby preventing fatigue when the personnel pinch the capsule 3 for washing liquid for a long time during use, resulting in liquid leakage during the liquid absorption process, and increasing the convenience of using the dropper. The reset device 5 includes a reset ring 501 fixedly mounted on the surface of the dropper body 1, and the reset ring 501 is fixedly mounted on the surface of the dropper body 1. The reset spring 502 is symmetrically mounted on the side of the reset ring 501, and one end of the reset spring 502 is fixedly connected to the reset ring 501, and the other end of the reset spring 502 is fixedly connected to one side of the clamping plate 403, thereby satisfying the requirement that the reset spring 502 resets the clamping device 4 after each use, so that the capsule 3 resumes the next liquid absorption work;

[0024] The specific implementation process is as follows:

[0025] During use, the dropper body 1 is inserted into a six-well plate or other container for placing brain slices, so that the filter ring 201 contacts the bottom of the container. Since the filter ring 201 is made of soft materials such as rubber, the filter ring 201 can produce a certain deformation. When the filter ring 201 contacts the bottom of the container, the filter ring 201 isolates the dripper position of the dropper body 1, forming a space between the dripper and the filter ring 201. The liquid in the container flows to the dripper position through the filter hole 202, so that the dropper body 1 absorbs the liquid, while the brain slices are blocked to the outside by the filter ring 201 and separated from the dripper, ensuring that only the liquid is absorbed during the washing process, and the brain slices are not absorbed. In addition, since the filter ring 201 is made of soft materials such as rubber, the dropper body 1 can be applied to more angles, thereby absorbing the liquid at various angles.

[0026] Example 2:

[0027] See also Figure 1-2 The utility model provides a technical solution: a dropper for rinsing and changing liquid for brain slices, comprising a dropper body 1, a filter device 2 fixedly installed under the dropper body 1, the filter device 2 comprising a filter ring 201 fixedly installed at one end of the dropper body 1, the filter ring 201 is made of soft rubber material, so that the filter ring 201 can be deformed during use and contact and seal with the bottom of the six-well plate, so that the brain slices can be isolated during the suction process and only liquid can pass through, a plurality of filter holes 202 are evenly opened on the surface of the filter ring 201, a capsule 3 is fixedly installed above the dropper body 1, a clamping device 4 is fixedly installed on the surface of the dropper body 1, the clamping device 4 comprises a clamping ring 401 fixedly installed on the surface of the dropper body 1, clamping grooves 402 are fixedly installed on both sides of the clamping ring 401, a clamping plate 403 is installed in the clamping groove 402, the clamping plate 403 is movably connected to the clamping groove 402 through an axis, and one end of the clamping plate 403 is fixedly mounted with a clamping plate The clamping plate 403 is fixedly mounted with a clamping pressure plate 405, thereby preventing fatigue when the personnel pinch the capsule 3 for washing liquid for a long time during use, resulting in liquid leakage during the liquid absorption process, and increasing the convenience of using the dropper. The reset device 5 includes a reset ring 501 fixedly mounted on the surface of the dropper body 1, and the reset ring 501 is fixedly mounted on the surface of the dropper body 1. The reset spring 502 is symmetrically mounted on the side of the reset ring 501, and one end of the reset spring 502 is fixedly connected to the reset ring 501, and the other end of the reset spring 502 is fixedly connected to one side of the clamping plate 403, thereby satisfying the requirement that the reset spring 502 resets the clamping device 4 after each use, so that the capsule 3 resumes the next liquid absorption work;

[0028] The specific implementation process is as follows:

[0029] When in use, by holding the clamping pressure plate 405, when the filtering device 2 at one end of the dropper body 1 is extended into the container, the clamping pressure plate 405 is pressed, so that the clamping pressure plate 405 is forced to move, and one end of the clamping pressure plate 405 is adjusted in angle by the axis in the clamping groove 402. The adjustment of the clamping pressure plate 405 drives the clamping block 404 at one end to move, so that the clamping block 404 contacts the capsule 3 and applies pressure to the capsule 3, causing the capsule 3 to deform and absorb the liquid in the container. When it is necessary to release the liquid and use it next time, it is only necessary to cancel the pressure on the clamping pressure plate 405, so that the return spring 502 applies an outward thrust to the clamping plate 403 through its own elastic restoring force, so that the clamping plate 403 drives the clamping block 404 to separate from the capsule 3, so that the capsule 3 is restored, which is convenient for the next washing work.

[0030] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the present invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the present invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be encompassed within the present invention. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

Claims

1. A dropper for rinsing and changing liquid for brain slices, comprising a dropper body (1), characterized in that: A filtering device (2) is fixedly provided below the dropper body (1), a capsule (3) is fixedly provided above the dropper body (1), a clamping device (4) is fixedly provided on the surface of the dropper body (1), and a resetting device (5) is fixedly provided on the surface of the dropper body (1); The filtering device (2) comprises a filtering ring (201) fixedly mounted on one end of the dropper body (1), and a plurality of filtering holes (202) are evenly formed on the surface of the filtering ring (201).

2. The dropper for rinsing and replacing brain slices according to claim 1, characterized in that: The filter ring (201) is made of soft rubber material.

3. The dropper for rinsing and replacing brain slices according to claim 1, characterized in that: The clamping device (4) comprises a clamping ring (401) fixedly mounted on the surface of the dropper body (1); clamping grooves (402) are fixedly provided on both sides of the clamping ring (401); a clamping plate (403) is provided in the clamping groove (402); the clamping plate (403) and the clamping groove (402) are movably connected via an axis; a clamping block (404) is fixedly provided at one end of the clamping plate (403); an arc-shaped groove is provided on one side of the clamping block (404); and a clamping pressure plate (405) is fixedly provided on the surface of the clamping plate (403).

4. The dropper for rinsing and replacing brain slices according to claim 3, characterized in that: The arc-shaped groove on the surface of the clamping block (404) is adapted to the size of the capsule (3).

5. The dropper for rinsing and replacing brain slices according to claim 4, characterized in that: The reset device (5) comprises a reset ring (501) fixedly mounted on the surface of the dropper body (1); a reset spring (502) is symmetrically provided on the side of the reset ring (501); one end of the reset spring (502) is fixedly connected to the reset ring (501); and the other end of the reset spring (502) is fixedly connected to one side of the clamping plate (403).

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