Cell separation device

Abstract

The utility model relates to the technical field of cell separation, and discloses a cell separation device, and an automatic cell vessel limiting mechanism comprises a connecting shaft rod, a connecting shaft core, a connecting shaft core and a cell vessel, the deflection axis is connected to the other end of the connecting shaft rod; one end of the motion shaft rod is connected to the deflection axis; the movable shaft center is connected to the other end of the movable shaft rod; and the clamping limiting frame is connected to the connecting shaft rod. The connecting shaft rod is pulled inwards through the deflection axis, the bottom end of the connecting shaft rod deflects around the connecting axis, the clamping limiting frame connected with the top end of the connecting shaft rod is driven to synchronously conduct clamping deflection, the clamping limiting frame clamps and fixes the cell vessel, the stability of the cell vessel is guaranteed, and meanwhile the cell vessel is prevented from being damaged. And the automatic cell vessel limiting mechanism can be used for fixedly clamping various cell vessels with different sizes.

Description

Technical Field

[0001] The utility model relates to the field of cell separation, in particular to a cell separation device. Background Art

[0002] Single-celled organisms include all archaea and true bacteria, as well as many protists. Single cells, due to their simple structure, are able to circumvent other interfering factors, making them important specimens and unique research subjects in biochemical research. When studying single cells, isolating them individually is key. Most cell separation methods rely on collagenase digestion, resulting in low cell yields and poor digestion time control, which can easily affect cell activity and create a significant bottleneck in the clinical application of stem cells. Centrifugation, a commonly used separation method, requires clamping and positioning the cell dish to ensure its stability. Traditional separation dish positioning mechanisms can only position cell dishes of a single size, and are inconvenient to use because they cannot position and process cell dishes of various sizes. Utility Model Content

[0003] In order to solve the technical problem that a traditional separation dish positioning mechanism can only position cell dishes of a single size and cannot position cell dishes of various sizes, which is inconvenient to use, the utility model provides a cell separation device.

[0004] The utility model adopts the following technical solutions to achieve: a cell separation device, including a device body, the device body including a cell dish automatic limiting mechanism, the cell dish automatic limiting mechanism including:

[0005] A mounting base, the mounting base is mounted on the bottom end of the automatic limit mechanism of the cell dish; an electric push rod, the electric push rod is connected to the top of the mounting base; a support base, the support base is connected to the top end of the electric push rod; a connecting shaft block, the connecting shaft block is mounted on the edge surface of the mounting base; a connecting axis, the connecting axis is arranged on the outside of the connecting shaft block; a connecting shaft rod, one end of the connecting shaft rod is connected to the connecting shaft rod; a deflection axis, the deflection axis is connected to the other end of the connecting shaft rod; a moving shaft rod, one end of the moving shaft rod is connected to the deflection axis; a movable axis, the movable axis is connected to the other end of the moving shaft rod; a clamping limit frame, the clamping limit frame is connected to the connecting shaft rod.

[0006] The cell dish is placed in the inside of the cell dish automatic limiting mechanism, the bottom end of the cell dish contacts the support base, through the work of the electric push rod, the electric push rod drives the support base to be pressed down, with the pressing down of the support base, the movable shaft arranged outside the support base is pressed down synchronously, the movable shaft drives the moving shaft connected therewith to deflect synchronously, the deflection shaft connected at the top end of the moving shaft is pulled synchronously, the deflection shaft drives the connecting shaft connected therewith to move synchronously, the deflection shaft pulls the connecting shaft inward, the bottom end of the connecting shaft deflects around the connecting shaft, the clamping limiting frame connected at the top end of the connecting shaft is driven to deflect synchronously, the clamping limiting frame clamps and fixes the cell dish, the stability of the cell dish is ensured, and the cell dish automatic limiting mechanism can fix and clamp cell dishes of various sizes.

[0007] As a further improvement of the above scheme, the clamping limiting frame is provided with at least three groups, and the cell dish is clamped on the inner side of the clamping limiting frame.

[0008] As a further improvement of the above scheme, the support base is disc-shaped, and the cell dish is placed above the support base and supported by the support base.

[0009] As a further improvement of the above scheme, the support mechanism comprises:

[0010] The support base is installed at the bottom end of the support mechanism, the limiting frame is installed on the outer side of the support base, and the positioning dish is installed on the outer side of the limiting frame. The cell dish automatic limiting mechanism is installed in the inside of the positioning dish, and the installation base is connected to the bottom end of the positioning dish. The cell dish automatic limiting mechanism is placed on the inner side of the positioning dish, and the positioning dish ensures the stability of the cell dish automatic limiting mechanism.

[0011] As a further improvement of the above scheme, the device body comprises an installation base, a driving motor is connected above the installation base, a driving rod is connected above the driving motor, a driving disc is connected above the driving rod, and a support mechanism is connected to the top end of the driving disc. Through the work of the driving motor, the driving motor drives the driving rod to rotate, the driving disc connected at the top end of the driving rod rotates, the cell dish automatic limiting mechanism connected above the driving disc rotates, and the cell dish rotates to perform cell centrifugation operation.

[0012] Compared with the prior art, the cell dish automatic limiting mechanism has the advantages that:

[0013] 1. The utility model discloses a connecting shaft rod is pulled to the inside through the deflection axle center, and the bottom of connecting shaft rod is deflected around the connecting axle center, and the clamping limit frame connected to the top end of connecting shaft rod is driven to carry out clamping deflection simultaneously, and the clamping limit frame clamps and fixes cell dish to guarantee the stability of cell dish, and simultaneously, cell dish automatic positioner can fix and clamp various different size cell dishes.

[0014] 2. The utility model discloses the work of drive motor, and drive motor drives drive rod to rotate, and the drive disc connected to the top end of drive rod rotates, and the cell dish automatic positioner connected above drive disc rotates, and cell dish rotates to carry out cell centrifugal operation. DRAWINGS

[0015] Figure 1 It is the whole structure schematic diagram of the utility model;

[0016] Figure 2 It is the support mechanism connecting structure schematic diagram of the utility model;

[0017] Figure 3 It is the utility model Figure 2 Structure split schematic diagram;

[0018] Figure 4 It is the cell dish automatic positioner connecting structure schematic diagram of the utility model.

[0019] Main symbol explanation:

[0020] 1, device main body;2, install base;3, drive motor;4, drive rod;5, drive disc;6, support mechanism;61, support bottom plate;62, limit frame;63, positioning dish;7, cell dish automatic positioner;71, install base;72, electric push rod;73, support seat;74, connecting axle block;75, connecting axle center;76, connecting shaft rod;77, deflection axle center;78, movement axle rod;79, movable axle center;710, clamping limit frame;8, cell dish. SPECIFIC EMBODIMENT

[0021] Below, combining the drawings and specific embodiment, the utility model will be described further, need to explain, under the prerequisite of not conflicting, the following description each embodiment between or each technical feature between can be combined to form new embodiment.

[0022] Example 1:

[0023] Please combine Figures 1-4The embodiment provides a cell separation device, which comprises a device main body 1, the device main body 1 comprises a mounting base 2, a driving motor 3 is connected above the mounting base 2, a driving rod 4 is connected above the driving motor 3, a driving disc 5 is connected above the driving rod 4, and a supporting mechanism 6 is connected to the top end of the driving disc 5. A cell dish automatic limiting mechanism 7 is placed on the inner side of a positioning dish 63, the positioning dish 63 guarantees the stability of the cell dish automatic limiting mechanism 7, meanwhile, through the working of the driving motor 3, the driving motor 3 drives the driving rod 4 to rotate, the driving disc 5 connected to the top end of the driving rod 4 rotates, the cell dish automatic limiting mechanism 7 connected above the driving disc 5 rotates, and the cell dish 8 rotates to perform a cell centrifugation operation.

[0024] The supporting mechanism 6 is installed above the driving disc 5, and the supporting mechanism 6 is provided with at least four groups.

[0025] A supporting bottom plate 61 is installed at the bottom end of the supporting mechanism 6.

[0026] A limiting frame 62 is installed on the outer side of the supporting bottom plate 61.

[0027] A positioning dish 63 is installed on the outer side of the limiting frame 62. The cell dish automatic limiting mechanism 7 is installed in the positioning dish 63, and a mounting base 71 is connected to the bottom end of the positioning dish 63.

[0028] The cell dish automatic limiting mechanism 7 comprises:

[0029] The mounting base 71 is installed at the bottom end of the cell dish automatic limiting mechanism 7.

[0030] An electric push rod 72 is connected above the mounting base 71.

[0031] A supporting seat 73 is connected to the top end of the electric push rod 72. The supporting seat 73 is in a disc shape, the cell dish 8 is placed above the supporting seat 73, and the supporting seat 73 supports the cell dish 8.

[0032] A connecting shaft block 74 is installed on the edge surface of the mounting base 71.

[0033] A connecting shaft center 75 is arranged on the outer side of the connecting shaft block 74.

[0034] A connecting shaft rod 76 is connected to one end of the connecting shaft center 75.

[0035] A deflection shaft center 77 is connected to the other end of the connecting shaft rod 76.

[0036] A moving shaft 78 is connected to the deflection shaft 77 at one end;

[0037] A movable shaft 79 is connected to the other end of the moving shaft 78;

[0038] The clamping limit frame 710 is connected to the connecting shaft 76. The clamping limit frame 710 is provided with at least three groups, and the inner side of the clamping limit frame 710 clamps the cell dish 8. The three groups of clamping limit frames 710 clamp the cell dish 8.

[0039] When the cell dish 8 is placed in the cell dish automatic limiting mechanism 7, the bottom end of the cell dish 8 contacts the support seat 73. Through the work of the electric push rod 72, the electric push rod 72 is driven to shrink, the support seat 73 is driven to press down, and the movable shaft 79 provided outside the support seat 73 is synchronously pressed down. The movable shaft 79 drives the moving shaft 78 connected thereto to synchronously deflect, the deflection shaft 77 connected to the top end of the moving shaft 78 is synchronously pulled, the deflection shaft 77 drives the connecting shaft 76 connected thereto to synchronously move, the deflection shaft 77 pulls the connecting shaft 76 inward, the bottom end of the connecting shaft 76 deflects around the connecting shaft 75, and the clamping limit frame 710 connected to the top end of the connecting shaft 76 is driven to synchronously deflect and clamp. The clamping limit frame 710 clamps and fixes the cell dish 8, guarantees the stability of the cell dish 8, and can fix and clamp cell dishes 8 of various sizes.

[0040] The specific implementation steps of the utility model are as follows:

[0041] In use, the cell dish 8 is placed in the cell dish automatic limiting mechanism 7, the bottom end of the cell dish 8 contacts the support seat 73, the electric push rod 72 is driven to shrink through the work of the electric push rod 72, the support seat 73 is driven to press down, the movable shaft 79 provided outside the support seat 73 is synchronously pressed down, the movable shaft 79 drives the moving shaft 78 connected thereto to synchronously deflect, the deflection shaft 77 connected to the top end of the moving shaft 78 is synchronously pulled, the deflection shaft 77 drives the connecting shaft 76 connected thereto to synchronously move, the deflection shaft 77 pulls the connecting shaft 76 inward, the bottom end of the connecting shaft 76 deflects around the connecting shaft 75, and the clamping limit frame 710 connected to the top end of the connecting shaft 76 is driven to synchronously deflect and clamp. The clamping limit frame 710 clamps and fixes the cell dish 8, guarantees the stability of the cell dish 8, and can fix and clamp cell dishes 8 of various sizes.

[0042] Meanwhile, the cell dish automatic limiting mechanism 7 is placed inside the positioning dish 63, the positioning dish 63 guarantees the stability of the cell dish automatic limiting mechanism 7, meanwhile, through the work of the driving motor 3, the driving motor 3 drives the driving rod 4 to rotate, the driving disc 5 connected to the top of the driving rod 4 rotates, the cell dish automatic limiting mechanism 7 connected above the driving disc 5 rotates, and the cell dish 8 rotates to perform the cell centrifugation operation.

[0043] The above-mentioned embodiments are only preferred embodiments of the present application, and cannot be used to limit the scope of protection of the present application. Any non-essential changes and replacements made by those skilled in the art on the basis of the present application shall fall within the scope of protection of the present application.

Claims

1. A cell separation device comprising a device body, characterised in that, The device body comprises a cell dish automatic limiting mechanism, which comprises: A mounting base is installed at the bottom end of the cell dish automatic limiting mechanism; An electric push rod is connected above the mounting base; A support seat is connected at the top end of the electric push rod; A connecting shaft block is installed at the edge surface of the mounting base; A connecting shaft core is arranged outside the connecting shaft block; One end of a connecting shaft rod is connected with the connecting shaft core; A deflection shaft core is connected at the other end of the connecting shaft rod; One end of a movement shaft rod is connected on the deflection shaft core; An activity shaft core is connected at the other end of the movement shaft rod; A clamping limiting frame is connected on the connecting shaft rod.

2. A cell separation device as claimed in claim 1, wherein The device body comprises a mounting base, a drive motor is connected above the mounting base, a drive rod is connected above the drive motor, a drive disc is connected above the drive rod, and a support mechanism is connected at the top end of the drive disc.

3. A cell separation device as claimed in claim 2, wherein The support mechanism comprises: A support bottom plate is installed at the bottom end of the support mechanism; A limiting frame is installed outside the support bottom plate; A positioning dish is installed outside the limiting frame.

4. A cell separation device as claimed in claim 3, wherein the magnetic field is applied by a plurality of magnets arranged in a circular pattern around the cell separation device. The cell dish automatic limiting mechanism is installed inside the positioning dish, and the mounting base is connected at the bottom end of the positioning dish. ​ 5. A cell separation device as claimed in claim 3, wherein the magnetic field is applied by a plurality of magnets arranged in a circular pattern around the cell separation device. The support mechanism is installed above the drive disc, and the support mechanism is provided with at least four groups. ​ 6. A cell separation device as claimed in claim 1, wherein, The clamping limiting frame is provided with at least three groups, and the inner side of the clamping limiting frame clamps a cell dish, and three groups of the clamping limiting frame clamp the cell dish.

7. A cell separation device as claimed in claim 6, wherein the magnetic field is applied by a plurality of magnets arranged in a circular pattern around the cell separation device. 5 The support seat is disc-shaped, the cell dish is placed above the support seat, and the support seat supports the cell dish.

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