Full-automatic solid-phase extraction instrument

Abstract

The utility model discloses a full-automatic solid-phase extraction instrument which comprises a chassis part, a consumable disc part is mounted on one side of the front section of the chassis part, a filter pressing part is mounted on the other side of the front section of the chassis part, an X-axis cantilever part is mounted on the rear side of the chassis part, a Y-axis cantilever part is movably connected to the X-axis cantilever part, and the Y-axis cantilever part is movably connected to the Y-axis cantilever part. And the Y-axis cantilever component is provided with a pipetting component and a clamping jaw component. The extraction processes such as shifting and filtering can be fully automatically carried out, the labor intensity of operators is reduced, and the working efficiency is improved.

Description

Technical Field

[0001] This invention belongs to the field of nucleic acid purification and extraction technology, and in particular relates to a fully automated solid-phase extraction instrument. Background Technology

[0002] Currently, many instruments do not fully automate the pressure filtration process for samples, requiring a lot of manual operation, which leads to low efficiency. Utility Model Content

[0003] In order to solve the above technical problems, the present invention is achieved through the following technical solutions:

[0004] A fully automated solid-phase extraction instrument includes a chassis component. A consumable tray component is installed on one side of the front section of the chassis component, and a filter press component is installed on the other side. An X-axis cantilever component is installed on the rear side of the chassis component. A Y-axis cantilever component is movably connected to the X-axis cantilever component. A pipetting component and a gripper component are installed on the Y-axis cantilever component.

[0005] Furthermore, the chassis component includes a base plate, with feet installed at the bottom of the base plate. Waste gun head boxes are also installed in the middle and at the bottom of the base plate. An electronic control bracket is installed at the rear end of the base plate. A main board, an I / O board, and a driver board are installed on one side of the electronic control bracket, and a pressure regulating valve, a solenoid valve, and a proportional valve are installed on the other side. A power supply assembly is also installed on the electronic control bracket on the side of the pressure regulating valve. A first slide rail is also installed on the base plate on this side. A third slide rail support frame is also installed at the front of the base plate, and a third slide rail is installed on the third slide rail support frame.

[0006] Furthermore, the consumable tray component includes a consumable base, with a magnet at one end and a handle at the other end; the consumable base is provided with a reagent bottle placement tray, a reagent bottle, and a syringe tip holder, and the bottom of the consumable base is also provided with a first slider that is slidably connected to a first slide rail.

[0007] Furthermore, the filter press component is provided with a shaking assembly, a 96-hole plate, a connecting plate and a filter plate in sequence on the base plate. Second slide rails are also provided on both sides of the filter press component, and the filter press component is slidably connected on the second slide rails. A lead screw motor is also installed on one side of the second slide rail, and the lead screw motor drives the filter press component to slide on the second slide rail. A filter press component drive motor is provided at the upper end of the filter press component to drive the filter press component to move up and down.

[0008] Furthermore, the X-axis cantilever component includes a support frame, a first synchronous pulley is mounted on the upper end of the support frame, the first synchronous pulley is driven by a first motor, a third slide rail is also provided on the outer side of the first synchronous pulley, a first optocoupler is also mounted on one end of the third slide rail, and a first drag chain is also mounted on the upper end of the support frame.

[0009] Furthermore, the Y-axis cantilever component includes a mounting bracket, a third slider is mounted on the lower end of the mounting bracket, the third slider is slidably connected to a third slide rail, a first drag chain connects the mounting bracket and the support bracket, a fourth slide rail, a second synchronous pulley and a second motor are mounted on one side of the mounting bracket, the second motor drives the second synchronous pulley, a fifth slide rail, a third synchronous pulley and a third motor are mounted on the other side of the mounting bracket, the third motor drives the third synchronous pulley; the mounting bracket is connected to the pipetting component and the gripper component by drag chains respectively, and a first synchronous pulley pressure plate is also mounted on the mounting bracket.

[0010] Furthermore, the pipetting component includes a pipette support frame, a fourth slider mounted on the pipette support frame, the fourth slider being slidably connected to a fourth slide rail, a second synchronous pulley pressure plate being provided at the upper end of the fourth slider, a sixth slide rail mounted on the pipette support frame, a sixth slider mounted on the sixth slide rail, a lead screw mounted on the sixth slider, a fourth motor mounted on the pipette mounting bracket, a fourth synchronous pulley mounted on the fourth motor, the fourth synchronous pulley being connected to the lead screw, and a pipette mounted on the sixth slider.

[0011] Furthermore, the gripper component includes a gripper support frame, on which a fifth slider is mounted. The fifth slider is slidably connected to a fifth slide rail. A fifth motor is also mounted on the gripper support frame. The fifth motor is connected to a fifth synchronous pulley. A gripper synchronous pulley pressure block is mounted on the fifth synchronous pulley. A cylinder mounting plate is mounted on the gripper synchronous pulley pressure block. A finger cylinder is mounted on the cylinder mounting plate. A gripper is mounted on the finger cylinder. A second optocoupler is also mounted on the top of the gripper support frame.

[0012] The utility model has the following beneficial effects:

[0013] Hydraulic filtration can be performed automatically, increasing work efficiency. Of course, not every product implementing this invention needs to achieve all the advantages described above simultaneously. Attached Figure Description

[0014] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0015] Figure 1 This is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2This is a schematic diagram of the chassis component structure of this utility model;

[0017] Figure 3 This is a schematic diagram of the consumable tray component of this utility model;

[0018] Figure 4 This is a schematic diagram of the filter press component of this utility model;

[0019] Figure 5 This is a schematic diagram of the X-axis cantilever component structure of this utility model;

[0020] Figure 6 This is a schematic diagram of the Y-axis cantilever component structure of this utility model;

[0021] Figure 7 This is a schematic diagram of the pipetting component of this utility model;

[0022] Figure 8 This is a schematic diagram of the gripper component of this utility model. Detailed Implementation

[0023] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.

[0024] Example 1

[0025] Please see Figure 1 As shown,

[0026] A fully automated solid-phase extraction instrument includes a chassis component 1. A consumable tray component 2 is installed on one side of the front section of the chassis component 1, and a filter press component 3 is installed on the other side. An X-axis cantilever component 4 is installed on the rear side of the chassis component 1. A Y-axis cantilever component 5 is movably connected to the X-axis cantilever component 4. A pipetting component 6 and a gripper component are installed on the Y-axis cantilever component 5.

[0027] The chassis component 1 includes a base plate 11, with feet 12 installed at the bottom of the base plate 11. Waste gun head boxes 13 are also installed in the middle and at the bottom of the base plate. An electrical control bracket is installed at the rear end of the base plate. A main board 110, an I / O board 111, and a drive board 19 are installed on one side of the electrical control bracket, and a pressure regulating valve 16, a solenoid valve 17, and a proportional valve 18 are installed on the other side. A power supply assembly 15 is also installed on the electrical control bracket on the side of the pressure regulating valve 16. A first slide rail 14 is also installed on the base plate 11 on this side. A third slide rail support frame 112 is also installed at the front of the base plate, and a third slide rail 113 is installed on the third slide rail support frame 112.

[0028] The consumable tray component 2 includes a consumable base 21, with a magnet 22 at one end and a handle 23 at the other end. The consumable base 21 is provided with a reagent bottle placement tray 26, a reagent bottle 25, and a gun tip holder 24. The bottom of the consumable base 21 is also provided with a first slider and is slidably connected to a first slide rail 14.

[0029] The filter press component 3 has a shaking assembly 31, a 96-hole plate 32, a connecting plate 33, and a filter plate 34 arranged sequentially on the base plate 1. Second slide rails 36 are also provided on both sides of the filter press component 35, and the filter press component 35 is slidably connected to the second slide rails 36. A lead screw motor 37 is also installed on one side of the second slide rails 36. The lead screw motor 37 drives the filter press component 35 to slide on the second slide rails 36. A filter press component drive motor is provided at the upper end of the filter press component to drive the filter press component to move up and down.

[0030] The X-axis cantilever component 4 includes a support frame 41, on which a first synchronous pulley 42 is mounted. The first synchronous pulley 42 is driven by a first motor 43. A third slide rail 46 is also provided on the outer side of the first synchronous pulley 42. A first optocoupler 44 is also mounted on one end of the third slide rail 46. A first drag chain 45 is also mounted on the upper end of the support frame 41.

[0031] The Y-axis cantilever component 5 includes a mounting frame 51. A third slider 55 is mounted on the lower end of the mounting frame 51. The third slider 55 is slidably connected to a third slide rail 46. A first drag chain 45 is connected between the mounting frame 51 and the support frame 41. A fourth slide rail 52, a second synchronous pulley 53, and a second motor 54 are mounted on one side of the mounting frame 51. The second motor 54 drives the second synchronous pulley 53. A fifth slide rail 58, a third synchronous pulley 57, and a third motor 510 are mounted on the other side of the mounting frame 51. The third motor 510 drives the third synchronous pulley 57. The mounting frame 51 is connected to the pipetting component 6 and the gripper component 7 by drag chains. A first synchronous pulley pressure plate 59 is also mounted on the mounting frame 51.

[0032] The pipetting component includes a pipette support frame 61, on which a fourth slider 62 is mounted. The fourth slider 62 is slidably connected to a fourth slide rail 52. A second synchronous pulley pressure plate 63 is also provided at the upper end of the fourth slider 62. A sixth slide rail 67 is mounted on the pipette support frame 61, and a sixth slider 68 is mounted on the sixth slide rail 67. A lead screw is mounted on the sixth slider 68. A fourth motor 65 is mounted on the pipette mounting frame 61, and a fourth synchronous pulley 64 is mounted on the fourth motor 65. The fourth synchronous pulley 64 is connected to the lead screw. A pipette 66 is mounted on the sixth slider 68.

[0033] The gripper component 7 includes a gripper support frame 71, on which a fifth slider 78 is mounted. The fifth slider 78 is slidably connected to a fifth slide rail 58. A fifth motor 73 is also mounted on the gripper support frame 71. The fifth motor 73 is connected to a fifth synchronous pulley 77. A gripper synchronous pulley pressure block 76 is mounted on the fifth synchronous pulley 77. A cylinder mounting plate 79 is mounted on the gripper synchronous pulley pressure block 76. A finger cylinder 72 is mounted on the cylinder mounting plate 79. A gripper 75 is mounted on the finger cylinder 72. A second optocoupler 74 is also mounted on the top of the gripper support frame 71.

[0034] The above are merely preferred embodiments of the present utility model and do not limit the present utility model. Any modifications, equivalent substitutions, or improvements made to the technical solutions described in the foregoing embodiments, or to some of the technical features, shall fall within the protection scope of the present utility model.

Claims

1. A fully automated solid-phase extraction instrument, characterized in that, The device includes a chassis component, on one side of the front section of which a consumable tray component is mounted and on the other side which a filter press component is mounted. An X-axis cantilever component is mounted on the rear side of the chassis component. A Y-axis cantilever component is movably connected to the X-axis cantilever component. A pipetting component and a gripper component are mounted on the Y-axis cantilever component.

2. The fully automated solid-phase extraction apparatus according to claim 1, characterized in that, The chassis component includes a base plate, with feet installed at the bottom of the base plate. Waste gun head boxes are installed in the middle and at the bottom of the base plate, respectively. An electronic control bracket is installed at the rear end of the base plate. A main board, I / O board, and driver board are installed on one side of the electronic control bracket, and a pressure regulating valve, solenoid valve, and proportional valve are installed on the other side. A power supply assembly is also installed on the electronic control bracket on the side of the pressure regulating valve. A first slide rail is also installed on the base plate on this side. A third slide rail support frame is also installed at the front of the base plate, and a third slide rail is installed on the third slide rail support frame.

3. The fully automated solid-phase extraction apparatus according to claim 1, characterized in that, The consumable tray component includes a consumable base, with a magnet at one end and a handle at the other end; the consumable base is provided with a reagent bottle placement tray, a reagent bottle and a pipette tip holder, and a first slider is provided at the bottom of the consumable base and is slidably connected to a first slide rail.

4. The fully automated solid-phase extraction apparatus according to claim 1, characterized in that, The filter press component has a shaking assembly, a 96-hole plate, a connecting plate and a filter plate arranged sequentially on the base plate. It also has a second slide rail on both sides, and the filter press component is slidably connected on the second slide rail. A lead screw motor is also installed on one side of the second slide rail. The lead screw motor drives the filter press component to slide on the second slide rail. The filter press component drive motor is provided at the upper end of the filter press component to drive the filter press component to move up and down.

5. The fully automated solid-phase extraction apparatus according to claim 1, characterized in that, The X-axis cantilever component includes a support frame, a first synchronous pulley is mounted on the upper end of the support frame, the first synchronous pulley is driven by a first motor, a third slide rail is also provided on the outer side of the first synchronous pulley, a first optocoupler is also mounted on one end of the third slide rail, and a first drag chain is also mounted on the upper end of the support frame.

6. The fully automated solid-phase extraction apparatus according to claim 1, characterized in that, The Y-axis cantilever component includes a mounting bracket. A third slider is mounted on the lower end of the mounting bracket, and the third slider is slidably connected to a third slide rail. A first cable chain connects the mounting bracket and the support bracket. A fourth slide rail, a second synchronous pulley, and a second motor are mounted on one side of the mounting bracket, with the second motor driving the second synchronous pulley. A fifth slide rail, a third synchronous pulley, and a third motor are mounted on the other side of the mounting bracket, with the third motor driving the third synchronous pulley. Cable chains are mounted on the mounting bracket to the pipetting component and the gripper component, respectively. A first synchronous pulley pressure plate is also mounted on the mounting bracket.

7. The fully automated solid-phase extraction apparatus according to claim 1, characterized in that, The pipetting component includes a pipette support frame, a fourth slider mounted on the pipette support frame, the fourth slider being slidably connected to a fourth slide rail, a second synchronous pulley pressure plate being provided at the upper end of the fourth slider, a sixth slide rail mounted on the pipette support frame, a sixth slider mounted on the sixth slide rail, a lead screw mounted on the sixth slider, a fourth motor mounted on the pipette mounting bracket, a fourth synchronous pulley mounted on the fourth motor, the fourth synchronous pulley being connected to the lead screw, and a pipette mounted on the sixth slider.

8. The fully automated solid-phase extraction apparatus according to claim 1, characterized in that, The gripper component includes a gripper support frame, on which a fifth slider is mounted and slidably connected to a fifth slide rail. A fifth motor is also mounted on the gripper support frame, connected to a fifth synchronous pulley. A gripper synchronous pulley pressure block is mounted on the fifth synchronous pulley, and a cylinder mounting plate is mounted on the gripper synchronous pulley pressure block. A finger cylinder is mounted on the cylinder mounting plate, and a gripper is mounted on the finger cylinder. A second optocoupler is also mounted on the top of the gripper support frame.

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