Intestinal flora sample pressing and sorting device

Abstract

The utility model relates to the technical field of flora sorting, in particular to an intestinal flora sample pressing and sorting device. The intestinal flora sample pressing and sorting device comprises a material collecting unit and a pressing unit, the material collecting unit comprises a containing box and a material guiding assembly, the material guiding assembly is used for guiding and discharging sorted intestinal flora liquid, and the pressing unit comprises a filtering assembly, a pressing assembly and a linear push rod. The filtering assembly is used for containing intestinal flora samples and conducting multi-stage filtering, the combining and pressing assembly comprises combining and pressing plates which are oppositely arranged, the filtering assembly is located between the two combining and pressing plates, and the linear push rod drives the two combining and pressing plates to conduct combining and pressing on the intestinal flora samples contained in the filtering assembly. According to the utility model, a pressing plate extrusion mode is adopted, so that the pressing plate and the filter component have a contact area which is large enough, an intestinal flora sample is quickly and fully extruded, efficient extraction of intestinal flora liquid is realized by utilizing multi-stage filtration, and the quality of the extracted intestinal flora liquid is ensured.

Description

Technical Field

[0001] This utility model relates to the field of microbial sorting technology, and in particular to a device for pressure sorting intestinal microbial samples. Background Technology

[0002] The gut microbiota is the normal microorganism in the human gut, mainly composed of bacteria, archaea, fungi, and viruses. A rich gut microbiota helps the body absorb nutrients from food, strengthens the immune system, and performs various other beneficial functions for overall health. On the other hand, the consequences of an imbalance or disorder in the gut microbiota extend beyond the intestines, affecting various bodily functions.

[0003] A common procedure involves extracting gut microbiota from feces. For example, patent application 202222270501.4 discloses a human gut microbiota collection device, which relates to the field of gut microbiota collection technology. The device includes a collection bag and a collection seat. The upper part of the collection seat has an adjacent first groove and a second groove. The first groove is used to place the collection bag, and the second groove is used to collect urine. A washer is rotatably connected to the upper surface of the collection seat. The outer edge of the washer is in close contact with the upper surface of the collection seat. A window is provided in the middle of the washer. The window overlaps with the openings of the first groove and the second groove. The device also includes a backrest, a first sample container, a drain tube, and a second sample container.

[0004] However, existing technologies cannot effectively prevent small impurities from mixing into the filtered fecal microbiota solution, which can lead to incomplete sorting and extraction of intestinal flora, resulting in relatively low efficiency and product quality during the extraction process. Utility Model Content

[0005] The purpose of this invention is to provide a pressure-sorting device for intestinal flora samples to solve the problem of incomplete sorting and extraction of intestinal flora in the prior art.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] This utility model discloses a device for combining and sorting intestinal flora samples, comprising:

[0008] The collection unit includes a container and a guiding component disposed at the bottom of the container, the guiding component being used to guide and discharge the sorted intestinal flora liquid;

[0009] The pressure-compression unit includes a filter assembly disposed within the containment box, a pressure-compression assembly disposed within the containment box, and a linear push rod disposed on the containment box. The filter assembly is used to contain intestinal flora samples and perform multi-stage filtration. The pressure-compression assembly includes pressure plates disposed opposite each other, with a pressure gap between the two pressure plates. The filter assembly is located between the two pressure plates. The stroke end of the linear push rod is connected to the pressure plates so that the linear push rod drives the two pressure plates to compress the intestinal flora samples contained in the filter assembly.

[0010] Optionally, the filter assembly includes multiple layers of first filter screens, the first filter screens are suspended inside the housing, and the first filter screens surround and form a housing chamber, the multiple layers of first filter screens sequentially cover the housing, and the mesh count of the multiple layers of first filter screens increases sequentially from the inner layer to the outer layer.

[0011] Optionally, the bottom surface of the accommodating box is provided with a discharge port corresponding to the first filter screen, and the two pressing plates are located within the diameter range of the discharge port to press the first filter screen together.

[0012] Optionally, a first blowing assembly is provided on the top inner wall of the accommodating box, the blowing direction of the first blowing assembly is vertically downward, and a second blowing assembly is provided on the bottom side of the pressing surface of the pressing plate, the blowing direction of the second blowing assembly is horizontally towards the discharge port.

[0013] Optionally, both the first purging assembly and the second purging assembly include a purging nozzle and a purging pipe connecting the air source and the purging nozzle. The purging nozzle of the first purging assembly is disposed on the top inner wall of the accommodating box, and the purging nozzle of the second purging assembly is embedded in the pressing surface of the pressing plate.

[0014] Optionally, one of the pressure plates in the pressure assembly is fixedly disposed in the receiving box, and the other pressure plate is slidably disposed in the receiving box, and the slidably disposed pressure plate is connected to the stroke end of the linear push rod.

[0015] Optionally, the material guiding assembly includes a material guiding bin disposed at the bottom of the receiving box. The top and bottom surfaces of the material guiding bin are both open, and the material guiding bin is a conical structure with a top opening larger than the bottom opening. The top opening of the material guiding bin is connected to the receiving box.

[0016] Optionally, the feeding assembly further includes a second filter screen disposed within the feeding bin for filtering the sorted intestinal flora solution.

[0017] Optionally, the intestinal flora sample pressure sorting device further includes a collection component, which includes a collection box located directly below the feed hopper and a plurality of collection tubes disposed within the collection box. The collection box has a transparent, visible wall, and the outer wall of the collection tubes has a scale marking indicating the capacity.

[0018] Optionally, the top of the container is provided with an air inlet and the bottom of the container is provided with an exhaust outlet, and the air inlet and the exhaust outlet are connected to form a ventilation channel.

[0019] Compared with the prior art, the beneficial effects of the intestinal flora sample pressure sorting device provided in this embodiment of the invention are as follows:

[0020] By setting up a collection unit and a pressing unit, the container provides the operating environment for intestinal flora sample extraction. The filter assembly is used to contain and filter the intestinal flora sample in multiple stages. A linear push rod drives two pressing plates to press the intestinal flora sample contained in the filter assembly, thereby achieving rapid and more thorough compression of the intestinal flora sample in the filter assembly. This can fully squeeze and break up large impurities such as undigested food residue in the intestinal flora sample, and achieve efficient extraction of intestinal flora liquid through multi-stage filtration. Then, the guide assembly quickly guides and discharges the sorted intestinal flora liquid, ensuring the quality of the extracted intestinal flora liquid and avoiding the presence of intestinal flora liquid residue or impurity accumulation in the container. Attached Figure Description

[0021] The technical solution of this utility model will be further described in detail below with reference to the accompanying drawings and embodiments. In the accompanying drawings:

[0022] Figure 1 A schematic diagram of the overall structure of the intestinal flora sample pressure sorting device provided in an embodiment of this utility model;

[0023] Figure 2 A schematic diagram of the assembly structure of the intestinal flora sample pressure sorting device provided in this embodiment of the utility model.

[0024] The markings in the attached diagram are as follows:

[0025] 1. Container box; 2. Feeding assembly; 21. Feeding bin; 3. Filtering assembly; 31. First filter screen; 4. Pressing assembly; 5. Linear push rod; 6. First purging assembly; 7. Second purging assembly; 8. Collection assembly; 81. Collection box; 82. Collection pipe. Detailed Implementation

[0026] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The preferred embodiments of this utility model will now be described in detail with reference to the accompanying drawings.

[0027] This utility model discloses a device for combining and sorting intestinal flora samples, such as... Figure 1 and Figure 2 Shown, including:

[0028] The material collection unit includes a receiving box 1 and a material guiding assembly 2 disposed at the bottom of the receiving box 1.

[0029] The pressure-compression unit includes a filter assembly 3 and a pressure-compression assembly 4 disposed within the container 1, and a linear push rod 5 disposed on the container 1. The filter assembly 3 is used to contain intestinal flora samples and perform multi-stage filtration. The pressure-compression assembly 4 includes opposing pressure plates with a pressure gap between them, and the filter assembly 3 is located between the two pressure plates. The stroke end of the linear push rod 5 is connected to the pressure plates, so that the linear push rod 5 drives the two pressure plates to compress the intestinal flora sample contained in the filter assembly 3.

[0030] Through the implementation of the above-mentioned intestinal flora sample compression and sorting device, the container 1 provides the operating environment for intestinal flora sample extraction, such as an anaerobic environment or a vacuum environment. The filter assembly 3 is used to contain and perform multi-stage filtration of the intestinal flora sample. A linear pusher 5 drives two pressing plates to compress the intestinal flora sample contained in the filter assembly 3 until the two pressing plates are pressed together. By using the pressing method, a sufficiently large contact area is achieved between the pressing plates and the filter assembly 3, thereby achieving rapid and more thorough compression of the intestinal flora sample within the filter assembly 3. This effectively breaks down large impurities such as undigested food residue in the intestinal flora sample, and multi-stage filtration achieves efficient extraction of the intestinal flora liquid. The sorted intestinal flora liquid is then rapidly guided and discharged by the guide assembly 2, ensuring the quality of the extracted intestinal flora liquid and preventing intestinal flora liquid residue or impurity accumulation within the container 1. Preferably, the linear pusher 5 is an electric pusher or a pneumatic pusher, etc., driving a linear stroke.

[0031] As described above, the degree of compression can be precisely controlled by adjusting the stroke of the linear push rod 5 to adapt to the filtration needs of different samples. For example: the first compression is stopped at 80% of the stroke for 1 minute, the second compression is stopped at 85% of the total stroke for 1 minute, the third compression is stopped at 80% of the total stroke for 30 seconds, and the final compression is stopped at the bottom for 3 minutes with continuous pressure.

[0032] Furthermore, the filter assembly 3 includes multiple layers of first filter screens 31. The first filter screens 31 are suspended inside the housing 1, and the first filter screens 31 surround and form a housing chamber. The multiple layers of first filter screens 31 sequentially cover the housing, and the mesh count of the multiple layers of first filter screens 31 increases sequentially from the inner layer to the outer layer.

[0033] Through the implementation of the above-described intestinal flora sample compression and sorting device, the accommodating chamber formed by the first filter 31 facilitates the placement of the intestinal flora sample within the first filter 31, ensuring that the first filter 31 completely covers the intestinal flora sample. This prevents large impurities in the intestinal flora sample from leaking out through the first filter 31, thus ensuring the efficiency of intestinal flora fluid extraction. Furthermore, the arrangement of multiple first filter screens 31 enables multi-stage screening. Multiple first filter screens 31 with different mesh sizes can sequentially filter materials to remove particles and impurities of different sizes, resulting in a purer intestinal flora fluid and improving the filtration efficiency and accuracy of the intestinal flora sample. Simultaneously, by suspending the first filter 31 within the accommodating box 1, the first filter 31 is fixed, facilitating subsequent compression by the driving pressure plate.

[0034] Furthermore, a discharge port corresponding to the first filter screen 31 is provided on the bottom surface of the container 1, and the two pressing plates are located within the diameter range of the discharge port to press the first filter screen 31.

[0035] By implementing the above-described intestinal flora sample compression and sorting device, the discharge port on the bottom surface of the container 1 connects the container 1 to the guide assembly 2 through the discharge port. This allows the intestinal flora sample in the first filter screen 31 to be compressed by the compression plates, and the filtered intestinal flora liquid flows into the guide assembly 2 through the discharge port. Simultaneously, the two compression plates, positioned within the diameter range of the discharge port, compress the first filter screen 31 to ensure that the filtered intestinal flora liquid from the first filter screen 31 falls completely into the discharge port during the compression process, preventing the intestinal flora liquid from overflowing into the container 1 and ensuring the extraction efficiency of the intestinal flora liquid.

[0036] Furthermore, a first blowing assembly 6 is provided on the top inner wall of the receiving box 1, and the blowing direction of the first blowing assembly 6 is vertically downward. A second blowing assembly 7 is provided on the bottom side of the pressing surface of the pressing plate, and the blowing direction of the second blowing assembly 7 is horizontally oriented towards the discharge port.

[0037] Through the implementation of the above-mentioned intestinal flora sample pressure sorting device, the first purging component 6 can blow away the residual intestinal flora liquid or impurities on the pressure plates to the discharge port, thus keeping the inside of the container 1 clean and ensuring the extraction efficiency of the intestinal flora liquid. At the same time, the second purging component 7 can blow away the residual intestinal flora liquid or impurities in the area between the two pressure plates at the bottom of the container 1 to the discharge port, further avoiding the presence of residual intestinal flora liquid or impurities in the container 1, ensuring the extraction efficiency of the intestinal flora liquid, preventing blockage, and ensuring smooth discharge.

[0038] Furthermore, both the first purging assembly 6 and the second purging assembly 7 include a purging nozzle and a purging pipe connecting the air source and the purging nozzle. The purging nozzle of the first purging assembly 6 is disposed on the top inner wall of the housing 1, and the purging nozzle of the second purging assembly 7 is embedded in the closing surface of the closing plate.

[0039] By implementing the above-mentioned intestinal flora sample pressure sorting device, a purge pipe is used to connect the purge nozzle and the air source, so that purge gas can be sprayed from the purge nozzle to achieve a uniform purge effect. The purge gas is preferably an inert gas such as nitrogen. The purge nozzle of the first purge assembly 6 is set on the top inner wall to purge the residual intestinal flora liquid or impurities on the pressure plate. The purge nozzle of the second purge assembly 7 is embedded in the pressure surface of the pressure plate to purge the residual intestinal flora liquid or impurities in the area between the two pressure plates at the bottom of the container 1. Simultaneously, by embedding the purge nozzle in the pressure surface of the pressure plate, the purge nozzle is prevented from affecting the adhesion and compression of the two pressure plates during the pressure process of the two pressure plates on the first filter screen 31.

[0040] Furthermore, one of the pressure plates in the pressure assembly 4 is fixedly installed in the housing 1, and the other pressure plate is slidably installed in the housing 1, and the slidably installed pressure plate is connected to the stroke end of the linear push rod 5.

[0041] By implementing the aforementioned intestinal flora sample pressing and sorting device, a linear pusher 5 drives one pressing plate to press against another fixed pressing plate, reducing the complexity of the drive system and lowering equipment costs and maintenance difficulty. In other words, controlling a single linear pusher 5 is relatively simple, facilitating automated and precise displacement control, and reducing the number of linear pushers 5 and related components, thus lowering system costs. It also ensures that the pressing plates maintain a uniform pressure distribution during the pressing process, improving the efficiency and quality of intestinal flora fluid extraction.

[0042] Furthermore, the material guiding assembly 2 includes a material guiding bin 21 disposed at the bottom of the containing box 1. The top and bottom surfaces of the material guiding bin 21 are both open, and the material guiding bin 21 is a conical structure with the top opening larger than the bottom opening. The top opening of the material guiding bin 21 is connected to the containing box 1.

[0043] Through the implementation of the above-mentioned intestinal flora sample pressure sorting device, the top opening of the guide chamber 21 is connected to the discharge port at the bottom of the container 1, allowing the sorted intestinal flora liquid to directly enter the guide chamber 21 from the discharge port of the container 1, reducing the possibility of impurities clogging the container 1 and intestinal flora liquid residue. Furthermore, the conical structure of the guide chamber 21, with its top opening larger than its bottom opening, allows the intestinal flora liquid entering the guide chamber 21 to be quickly discharged along the inclined inner wall of the guide chamber 21, preventing leakage and spillage during collection and reducing intestinal flora liquid residue within the guide chamber 21, thereby improving the extraction efficiency of the intestinal flora liquid.

[0044] Furthermore, the feeding assembly 2 also includes a second filter screen disposed in the feeding bin 21 for filtering the sorted intestinal flora liquid.

[0045] By implementing the above-mentioned intestinal flora sample pressure separation device, the second filter screen in the feed bin 21 can further and effectively remove impurities, cell debris and other smaller particulate matter from the intestinal flora liquid after it has been separated by the pressure separation unit, thereby improving the purity and quality of the flora liquid.

[0046] Furthermore, the intestinal flora sample pressure sorting device also includes a collection component 8. The collection component 8 includes a collection box 81 located directly below the feed hopper 21, and a plurality of collection tubes 82 disposed within the collection box 81. The collection box 81 is provided with a transparent, visible box wall, and the outer wall of the collection tubes 82 is provided with scale markings indicating the capacity.

[0047] The implementation of the aforementioned intestinal flora sample pressure sorting device allows for accurate indication of the volume of the collection tube 82 using the graduation markings on its outer wall. This facilitates precise control of the collection volume in each tube, improving the accuracy and repeatability of intestinal flora fluid extraction. Simultaneously, the transparent, visible box wall allows users to directly observe the volume of the flora fluid in the collection tubes 82 within the collection box 81, enabling real-time monitoring and control of the collection process and ensuring that the collected amount of flora fluid meets requirements. The arrangement of multiple collection tubes 82 also allows for simultaneous collection of multiple bacterial solutions, improving work efficiency and saving time.

[0048] Furthermore, the top of the container 1 is provided with an air inlet, and the bottom of the container 1 is provided with an exhaust outlet. The air inlet and the exhaust outlet are connected to form an air exchange channel.

[0049] By implementing the above-mentioned intestinal flora sample pressure sorting device, the air exchange channel formed by the air inlet and the air outlet can be used to replace the oxygen in the container 1 by introducing inert gas through the air inlet before sorting the intestinal flora sample. The replaced oxygen is then discharged through the air outlet to ensure that the container 1 is in an anaerobic environment. By providing anaerobic conditions, the growth and metabolism of some aerobic microorganisms can be inhibited, reducing their interference with the flora liquid and achieving more efficient extraction of intestinal flora liquid.

[0050] The intestinal flora sample compression and sorting device provided in this embodiment of the utility model sets up a collection unit and a compression unit. The container 1 provides the operating environment for intestinal flora sample extraction, such as an anaerobic environment or a vacuum environment. The container chamber formed by the first filter screen 31 is used to place the intestinal flora sample in the first filter screen 31 and make the first filter screen 31 completely cover the intestinal flora sample. The linear push rod 5 drives the two compression plates to compress the intestinal flora sample in the filter assembly 3 until the two compression plates are pressed and adhered. By using the compression method of the compression plates, it has a sufficiently large contact area with the filter assembly 3, thereby realizing the rapid and more thorough compression of the intestinal flora sample in the filter assembly 3. This can fully compress and break up large impurities such as undigested food residue in the intestinal flora sample, and realize the efficient extraction of intestinal flora liquid through multi-stage filtration. During the compression of the intestinal flora sample, the first purging component 6 and the second purging component are used to purge the residual intestinal flora liquid or impurities on the pressing plate and the container 1. Then, the guide hopper 21 re-filters and quickly guides the sorted intestinal flora liquid out, ensuring the quality of the extracted intestinal flora liquid and effectively avoiding the presence of residual intestinal flora liquid or impurities in the container 1.

[0051] It should be understood that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Those skilled in the art can modify the technical solutions described in the above embodiments, or make equivalent substitutions for some of the technical features; and all such modifications and substitutions should fall within the protection scope of the appended claims of this utility model.

Claims

1. A device for combining and sorting intestinal flora samples, characterized in that, The intestinal flora sample pressure sorting device includes: The collection unit includes a container and a guiding component disposed at the bottom of the container, the guiding component being used to guide and discharge the sorted intestinal flora liquid; The pressure-compression unit includes a filter assembly disposed within the containment box, a pressure-compression assembly disposed within the containment box, and a linear push rod disposed on the containment box. The filter assembly is used to contain intestinal flora samples and perform multi-stage filtration. The pressure-compression assembly includes pressure plates disposed opposite each other, with a pressure gap between the two pressure plates. The filter assembly is located between the two pressure plates. The stroke end of the linear push rod is connected to the pressure plates so that the linear push rod drives the two pressure plates to compress the intestinal flora samples contained in the filter assembly.

2. The intestinal flora sample pressure sorting device according to claim 1, characterized in that: The filter assembly includes multiple layers of first filter screens, which are suspended inside the housing and form a housing chamber. The multiple layers of first filter screens sequentially cover the housing, and the mesh count of the multiple layers of first filter screens increases sequentially from the inner layer to the outer layer.

3. The intestinal flora sample pressure sorting device according to claim 2, characterized in that: The bottom surface of the container is provided with a discharge port corresponding to the first filter screen, and the two pressing plates are located within the diameter range of the discharge port to press the first filter screen together.

4. The intestinal flora sample combining and sorting device according to claim 3, characterized in that: A first purging assembly is provided on the top inner wall of the accommodating box. The purging direction of the first purging assembly is vertically downward. A second purging assembly is provided on the bottom side of the pressing surface of the pressing plate. The purging direction of the second purging assembly is horizontally towards the discharge port.

5. The intestinal flora sample combining and sorting device according to claim 4, characterized in that: Both the first purging assembly and the second purging assembly include a purging nozzle and a purging pipe connecting the air source and the purging nozzle. The purging nozzle of the first purging assembly is disposed on the top inner wall of the accommodating box, and the purging nozzle of the second purging assembly is embedded in the closing surface of the closing plate.

6. The intestinal flora sample pressure sorting device according to claim 1, characterized in that: One of the pressure plates in the pressure-closing assembly is fixedly installed inside the receiving box, and the other pressure plate is slidably installed inside the receiving box, with the slidably installed pressure plate connected to the stroke end of the linear push rod.

7. The intestinal flora sample pressure sorting device according to claim 1, characterized in that: The material guiding assembly includes a material guiding bin disposed at the bottom of the receiving box. The top and bottom surfaces of the material guiding bin are both open, and the material guiding bin is a conical structure with the top opening larger than the bottom opening. The top opening of the material guiding bin is connected to the receiving box.

8. The intestinal flora sample pressure sorting device according to claim 7, characterized in that: The feeding assembly also includes a second filter screen disposed within the feeding bin, used to filter the sorted intestinal flora solution.

9. The intestinal flora sample pressure sorting device according to claim 7 or 8, characterized in that: The intestinal flora sample pressure sorting device also includes a collection component, which includes a collection box located directly below the feed hopper and multiple collection tubes disposed inside the collection box. The collection box has a transparent, visible wall, and the outer wall of the collection tubes has a scale marking indicating the capacity.

10. The intestinal flora sample combining and sorting device according to claim 8, characterized in that: The top of the container is provided with an air inlet, and the bottom of the container is provided with an exhaust outlet. The air inlet and the exhaust outlet are connected to form an air exchange channel.

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