Modularized fluorescence analysis and detection device

By using an electric actuator in the fluorescence analyzer to adjust the position of the irradiation part and the fluorescence receiving part, the measurement error problem caused by the inability to adjust in existing devices is solved, precise focusing and distance adjustment of the light beam are achieved, and the measurement accuracy and ease of operation are improved.

CN223485836UActive Publication Date: 2025-10-28JIANGXI WEIBANG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422362397.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-27
Publication Date
2025-10-28
Estimated Expiration
2034-09-27

AI Technical Summary

Technical Problem

In existing fluorescence analyzers, the irradiation part and the fluorescence receiving part cannot be adjusted, resulting in an inability to accurately focus on the sample cell, which may cause measurement errors.

Method used

A modular fluorescence analysis and detection device is designed. The irradiation part and the fluorescence receiving part are installed on an electric actuator, and their positions are adjusted by the electric actuator to ensure that the light beam of the irradiation part is concentrated on the sample cell and maintain the optimal distance between the fluorescence receiving part and the sample cell.

Benefits of technology

The precise focusing of the irradiation light beam and the optimal distance adjustment of the fluorescence receiving part are achieved, which improves the accuracy and simplicity of measurement.

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Abstract

The utility model discloses a modularized fluorescence analysis and detection device, which relates to the technical field of fluorescence analyzers and particularly comprises a first shell which is a control part, a display screen is arranged at the top of the first shell, a control mainboard is arranged in the first shell, and the modularized fluorescence analysis and detection device further comprises a second shell connected with the first shell; the second shell is a detection part, and a frame body for placing a sample cell is arranged in the second shell; a fluorescence receiving part is arranged at the top in the second shell, an irradiation part is arranged at the bottom in the second shell, the fluorescence receiving part is located above the sample cell, and the irradiation part is located below the sample cell. During use, the first electric actuator can be controlled to move by operating the keys, so that the positions of the fluorescence receiving part and the irradiation part are adjusted, and a proper distance is kept between the optical filter group at the bottom of the fluorescence receiving part and the sample cell; and the light beams emitted by the irradiation part can be driven by controlling the first electric actuator to be completely concentrated on the sample cell.
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Description

Technical Field

[0001] This utility model relates to the field of fluorescence analyzer technology, specifically a modular fluorescence analysis and detection device. Background Technology

[0002] The basic principle of a fluorescence analyzer is to utilize the absorption of light energy by chemical substances in a sample under specific excitation conditions, which then emits a fluorescence spectrum. This fluorescence spectrum is closely related to the chemical composition of the sample. By measuring the intensity and characteristic peak positions of the fluorescence spectrum, the composition and properties of the sample can be determined quickly and accurately. Fluorescence analyzers also feature high accuracy, high reliability, and ease of operation, making them an indispensable tool in scientific research and production. Therefore, fluorescence analyzers have wide applications in fields such as biomedicine, materials science, environmental monitoring, and food safety.

[0003] In existing fluorescence analyzers, the irradiation and fluorescence receiving sections are fixed after the sample cell is placed inside, making it impossible to adjust the distance between the irradiation and fluorescence receiving sections and the sample cell. In particular, if the irradiation section cannot be focused onto the sample cell, errors may occur. Therefore, we propose a modular fluorescence analysis and detection device. Utility Model Content

[0004] To address the shortcomings of existing irradiation and fluorescence receiving units that cannot be adjusted, this invention provides a modular fluorescence analysis and detection device. It has the advantage of mounting the irradiation and fluorescence receiving units on a first electric actuator, allowing the first electric actuator to drive them for adjustment, thus solving the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model is implemented through the following technical solution: a modular fluorescence analysis and detection device is designed, including a first shell, the first shell being a control part, a display screen being provided on the top of the first shell, and a control motherboard being provided inside it, characterized in that it further includes a second shell connected to the first shell;

[0006] The second outer shell is the detection part, and a frame for placing the sample cell is provided inside the second outer shell;

[0007] The second housing has a fluorescence receiver at the top and an irradiation unit at the bottom. The fluorescence receiver is located above the sample cell, while the irradiation unit is located below the sample cell.

[0008] The fluorescence receiver and the irradiation unit are both mounted on the first electric actuator. The fluorescence receiver and the irradiation unit move closer to or away from the sample cell under the drive of the first electric actuator. The fluorescence receiver, the irradiation unit, the first electric actuator, and the display screen are electrically connected to the control main board.

[0009] Preferably, the fluorescence receiver is located directly above the sample cell, while the irradiation unit is located on the lower side of the sample cell.

[0010] Preferably, the frame for placing the sample cell includes a detection slot horizontally disposed within the second housing, and a placement rack is provided inside the detection slot. The two sides of the placement rack are respectively connected to the inner wall of the detection slot via guide rails.

[0011] The rack is equipped with a slot for placing the sample cell, and the sample cell is placed in the slot.

[0012] The detection slot is also equipped with a second electric actuator that is electrically connected to the control main board. The telescopic end of the second electric actuator is connected to the placement frame, and the placement frame is pulled in and out of the detection slot under the drive of the second electric actuator.

[0013] Preferably, the first electric actuator includes a first electric telescopic rod electrically connected to the control main board, and a connecting frame is provided on the telescopic end of the first electric telescopic rod;

[0014] The fluorescent receiving part and the irradiation part are respectively mounted on the connecting frame. The end of the first electric telescopic rod away from the connecting frame is provided with a connecting seat, which is detachably connected to the inner wall of the second outer shell.

[0015] Preferably, a support is provided on one side of the connecting frame, and a guide shaft extending vertically toward the connecting seat is installed on the support. A guide seat is movably sleeved on the guide shaft, and the guide seat is installed on the cylinder of the first electric telescopic rod.

[0016] Preferably, the fluorescence receiving unit includes a first housing, and from one end of the first housing to the other end are sequentially provided a photomultiplier tube, a first slit, an emission monochromator, a first lens group, and a filter group, with the filter group facing the sample cell;

[0017] The irradiation unit includes a second housing, from one end of the second housing to the other end there are arranged a second lens group, an excitation monochromator, a second slit and a light source, with the second lens group facing the sample cell.

[0018] Preferably, the opening edge of the detection slot is provided with a sealing groove, and a sealing plate is provided at the end of the placement rack. When the placement rack is completely placed in the detection slot, the sealing plate is placed in the sealing groove.

[0019] Preferably, the top of the first housing is also provided with operation buttons that are electrically connected to the control motherboard.

[0020] Compared with the prior art, this utility model allows the movement of the first electric actuator to be controlled by operating buttons, thereby adjusting the position of the fluorescence receiving unit and the irradiation unit, so that the filter group at the bottom of the fluorescence receiving unit is kept at a suitable distance from the sample cell. Moreover, the first electric actuator can be controlled to ensure that the light beam emitted by the irradiation unit is completely concentrated on the sample cell. The signal captured by the fluorescence receiving unit is transmitted to the control main board, analyzed by the control main board, and displayed on the display screen. The operation is simple and convenient. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the structure of the present utility model. Figure 1 .

[0022] Figure 2 This is a schematic diagram of the structure of the present utility model. Figure 2 .

[0023] Figure 3 This is a cross-sectional view of the front of the present invention. Figure 1 .

[0024] Figure 4 This is a cross-sectional view of the front of the present invention. Figure 2 .

[0025] Figure 5 This is a sectional view of the side of this utility model.

[0026] Figure 6 This is a schematic diagram of the structure of the first electric actuator of this utility model.

[0027] Figure 7 This is a schematic diagram of the internal structure of the fluorescent receiving part of this utility model.

[0028] Figure 8 This is a schematic diagram of the structure of the irradiation unit and the first electric actuator of this utility model.

[0029] Figure 9 This is a schematic diagram of the structure of the irradiation part of this utility model.

[0030] In the diagram: 1. First outer casing; 2. Display screen; 3. Operation buttons; 4. Second outer casing; 5. Sealing groove; 6. Placement rack; 7. Sealing plate; 8. Placement groove; 9. Detection groove; 10. First electric actuator; 11. Fluorescent receiver; 12. Second electric actuator; 13. Irradiation unit; 14. Control main board; 15. Exhaust fan; 16. Partition plate; 17. Connecting seat; 18. First electric telescopic rod; 19. Guide shaft; 20. Guide seat; 21. Support; 22. Connecting frame; 23. Photomultiplier tube; 24. First slit; 25. Emitting monochromator; 26. First lens group; 27. Filter group; 28. Second lens group; 29. ​​Excitation monochromator; 30. Second slit; 31. Light source. Detailed Implementation

[0031] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0032] Please see Figures 1 to 9 This utility model provides a technical solution: a modular fluorescence analysis and detection device, including a first shell 1, the first shell 1 being a control part, the top of the first shell 1 being provided with a display screen 2 and operation buttons 3, and the inside being provided with a control motherboard 14, the display screen 2 and operation buttons 3 being electrically connected to the control motherboard 14 respectively, the display screen 2 being a touch screen.

[0033] A second outer shell 4 is provided on one side of the first outer shell 1. The arrangement of the first outer shell 1 and the second outer shell 4 allows the entire fluorescence analysis and detection device to have two different modules. The second outer shell 4 is the detection part, which is independent and minimizes interference from external light sources. The second outer shell 4 contains a frame for placing the sample cell. Its specific structure includes a detection slot 9 horizontally set inside the second outer shell 4, and a placement rack 6 is provided inside the detection slot 9. The two sides of the placement rack 6 are connected to the inner wall of the detection slot through guide rails.

[0034] The placement rack 6 is provided with a placement slot 8 for placing the sample cell. The sample cell is placed in the placement slot 8. The sample cell can be a transparent container such as a test tube or culture flask, and the prepared test solution is contained inside.

[0035] The detection chamber 9 is also equipped with a second electric actuator 12 electrically connected to the control main board 14. The telescopic end of the second electric actuator 12 is connected to the placement frame 6. Driven by the second electric actuator 12, the placement frame 6 is pulled in and out of the detection chamber 9. Here, the second electric actuator 12 is an electric telescopic rod. The second electric actuator 12 can drive the placement frame 6 to extend out of the detection chamber 9, or drive the placement frame 6 that has been pulled out to retract back into the detection chamber 9. The second electric actuator 12 can slowly drive the placement frame 6 to move, so that the sample cell moves smoothly.

[0036] Located inside the second outer casing 4, an irradiation section 13 is provided below the sample cell. The irradiation section 13 does not necessarily need to be directly below the sample cell; it can be located on the lower side of the sample cell. For example... Figure 3 As shown in the figure, the irradiation section 13 is located directly below the sample cell, but as... Figure 4As shown, the irradiation unit 13 is located on the side of the sample cell. It should be noted that no matter where the irradiation unit 13 is located in the sample cell, the light beam emitted by it can irradiate the sample cell.

[0037] The light emitted after the sample cell is irradiated is received by the fluorescence receiver 11 located at its top. The fluorescence receiver 11 is positioned above the sample cell; in practical applications, it is most effective when located directly above. The specific structure of the fluorescence receiver 11 includes a first housing (not labeled in the figure); as... Figure 7 As shown, from one end of the first housing to the other end, there are sequentially arranged a photomultiplier tube 23, a first slit 24, an emission monochromator 25, a first lens group 26, and a filter group 27. The filter group 27 faces the sample cell. The photomultiplier tube 23 is electrically connected to the control main board. Therefore, the light emitted from the sample cell is filtered by the filter group 27 and then concentrated by the first lens group 26 onto the emission monochromator 25. The light beam emitted by the emission monochromator 25 is then captured by the photomultiplier tube 23 in the first slit 24. The photomultiplier tube 23 transmits the captured signal to the control main board 14. After analysis by the control main board 14, it is displayed on the display screen 2.

[0038] Most importantly, the fluorescence receiving unit 11 and the irradiation unit 13 in this application are adjustable, allowing the light beam emitted by the irradiation unit 13 to be better focused on the sample cell, and maintaining an optimal receiving distance between the bottom of the fluorescence receiving unit 11 and the sample. That is, both the fluorescence receiving unit 11 and the irradiation unit 13 are mounted on the first electric actuator 10, which is electrically connected to the control main board. The fluorescence receiving unit 11 and the irradiation unit 13 move closer to or further away from the sample cell under the action of the first electric actuator 10.

[0039] This application also discloses the specific structure of the first electric actuator 10, which includes a first electric telescopic rod 18 electrically connected to the control main board 14, and a connecting frame 22 is provided on the telescopic end of the first electric telescopic rod 18. Figure 5 and Figure 8 As shown, the sides of the fluorescent receiving part 11 and the irradiation part 13 are respectively mounted on the connecting frame 22. The end of the first electric telescopic rod 18 away from the connecting frame 22 is provided with a connecting seat 17, and the connecting seat 17 is detachably connected to the inner wall of the second outer shell 4.

[0040] To ensure greater stability of the fluorescence receiving unit 11 and the irradiation unit 13 during the up-and-down movement of the first electric telescopic rod 18, a support 21 is provided on one side of the connecting frame 22. A guide shaft 19 extending vertically toward the connecting seat 17 is mounted on the support 21, and a guide seat 20 is movably sleeved on the guide shaft 19. The guide seat 20 is mounted on the cylinder of the first electric telescopic rod 18. Thus, when the first electric telescopic rod 18 moves up and down, the guide shaft 19 extends and retracts within the guide seat 20, providing guidance and ensuring smoother up-and-down movement of the fluorescence receiving unit 11 and the irradiation unit 13.

[0041] Therefore, when different sample cells are placed in the rack, the first electric actuator 10 can be controlled to move by operating the button, thereby adjusting the position of the fluorescence receiving part 11 and the irradiation part 13, so that the filter group 27 at the bottom of the fluorescence receiving part 11 is at a suitable distance from the sample cell, and the light beam emitted by the irradiation part 13 can be completely concentrated on the sample cell.

[0042] Finally, this application also proposes the components of the irradiation unit 13, such as... Figure 9 As shown, the irradiation unit 13 includes a second housing (not labeled in the figure), from one end of the second housing to the other, a second lens group 28, an excitation monochromator 29, a second slit 30, and a light source 31 are arranged sequentially. The second lens group 28 faces the sample cell. The light source 31 is electrically connected to the control main board 14. The light source 31 is a laser light source or an LED light source. The light passes through the second slit 30 and illuminates the excitation monochromator 29, and then is concentrated by the second lens group 28. In this application, the irradiation unit 13 is an excitation light source, so it is necessary to adjust the distance between the irradiation unit 13 and the sample cell, that is, to ensure that the light passing through the second lens group 28 can illuminate the sample cell as much as possible.

[0043] Based on the above embodiments, further optimization is possible. Since the detection groove 9 is open, in order to achieve a sealed state during detection, a sealing groove 5 is provided at the edge of the opening of the detection groove 9, and a sealing plate 7 is provided at the end of the placement rack 6. When the placement rack 6 is completely placed in the detection groove 9, the sealing plate 7 is placed in the sealing groove 5, and the opening of the detection groove 9 is sealed at this time.

[0044] Based on the above embodiments, further optimizations can be made. The first outer shell 1 and the second outer shell 4 are not connected and are sealed apart by the partition 16. It should also be emphasized that when the irradiation part 13 is installed at an angle or horizontally, the first electric actuator 10 connected to the irradiation part 13 can be installed on the partition 16.

[0045] Based on the above embodiments, further optimizations can be made. A ventilation louver is provided on the side of the first housing 1, and an exhaust fan 15 is provided on the first housing 1 at the position corresponding to the ventilation louver. A temperature sensor is also provided inside the first housing 1. The temperature sensor and the exhaust fan 15 are electrically connected to the control main board 14, respectively.

[0046] Based on the above embodiments, it should be further explained that the electrical connection in this application is achieved by means of wires, signal lines and control lines, thereby realizing the transmission of electrical energy and signals.

[0047] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model; the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. In addition, unless otherwise explicitly specified and limited, the terms "installed," "connected," and "linked" should be interpreted broadly. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. For those skilled in the art, the specific meaning of the above terms in this utility model can be understood according to the specific circumstances. Furthermore, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed or inherent to such process, method, article, or apparatus.

[0048] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A modular fluorescence analysis and detection device, comprising a first housing (1), the first housing (1) being a control unit, a display screen (2) on the top of the first housing (1), and a control motherboard (14) inside the first housing (1), characterized in that, It also includes a second outer shell (4) connected to the first outer shell (1); The second outer shell (4) is the detection part, and the second outer shell (4) is provided with a frame for placing the sample cell; The second outer shell (4) has a fluorescence receiving part (11) at the top and an irradiation part (13) at the bottom. The fluorescence receiving part (11) is located above the sample cell, while the irradiation part (13) is located below the sample cell. The fluorescence receiver (11) and the irradiation unit (13) are both mounted on the first electric actuator (10). The fluorescence receiver (11) and the irradiation unit (13) move closer to or further away from the sample cell under the drive of the first electric actuator (10). The fluorescence receiver (11), the irradiation unit (13), the first electric actuator (10) and the display screen (2) are electrically connected to the control motherboard (14).

2. The modular fluorescence analysis and detection device according to claim 1, characterized in that, The fluorescence receiver (11) is located directly above the sample cell, while the irradiation unit (13) is located on the lower side of the sample cell.

3. The modular fluorescence analysis and detection device according to claim 1, characterized in that, The frame for placing the sample cell includes a detection slot (9) horizontally set inside the second outer shell (4), and a placement rack (6) is provided inside the detection slot (9). The two sides of the placement rack (6) are respectively connected to the inner wall of the detection slot through guide rails. The placement rack (6) is provided with a placement slot (8) for placing the sample pool, and the sample pool is placed in the placement slot (8); The detection slot (9) is also equipped with a second electric actuator (12) that is electrically connected to the control main board (14). The telescopic end of the second electric actuator (12) is connected to the placement rack (6). Driven by the second electric actuator (12), the placement rack (6) is pulled in and out of the detection slot (9).

4. The modular fluorescence analysis and detection device according to any one of claims 1-3, characterized in that, The first electric actuator (10) includes a first electric telescopic rod (18) electrically connected to the control main board (14), and a connecting frame (22) is provided on the telescopic end of the first electric telescopic rod (18); The fluorescent receiving part (11) and the irradiation part (13) are respectively mounted on the connecting frame (22). The first electric telescopic rod (18) is provided with a connecting seat (17) at one end away from the connecting frame (22). The connecting seat (17) is detachably connected to the inner wall of the second outer shell (4).

5. The modular fluorescence analysis and detection device according to claim 4, characterized in that, A support (21) is provided on one side of the connecting frame (22). A guide shaft (19) extending vertically toward the connecting seat (17) is installed on the support (21). A guide seat (20) is movably sleeved on the guide shaft (19). The guide seat (20) is installed on the cylinder of the first electric telescopic rod (18).

6. The modular fluorescence analysis and detection device according to claim 5, characterized in that, The fluorescence receiver (11) includes a first housing, and from one end of the first housing to the other end are arranged a photomultiplier tube (23), a first slit (24), an emission monochromator (25), a first lens group (26), and a filter group (27), with the filter group (27) facing the sample cell; The irradiation unit (13) includes a second housing, from one end of the second housing to the other end there are arranged a second lens group (28), an excitation monochromator (29), a second slit (30) and a light source (31), the second lens group (28) facing the sample cell.

7. The modular fluorescence analysis and detection device according to claim 1, characterized in that, The opening edge of the detection groove (9) is provided with a sealing groove (5), and a sealing plate (7) is provided at the end of the placement rack (6). When the placement rack (6) is completely placed in the detection groove (9), the sealing plate (7) is placed in the sealing groove (5).

8. The modular fluorescence analysis and detection device according to claim 6, characterized in that, The top of the first casing (1) is also provided with operation buttons (3) that are electrically connected to the control motherboard (14).

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