Concentration and purification device for total glycosides of centella asiatica

Abstract

The utility model discloses a concentration and purification device for total glycosides of centella asiatica, which relates to the technical field of plant component extraction equipment, and comprises a desolventizing tank body, a desolventizing tank body, a desolventizing tank body, a desolventizing tank body, a desolventizing tank body, a desolventizing tank body and a desolventizing tank body, the desolventizing assembly is arranged at the top end of the accommodating cavity; the pulse generation assembly comprises a power supply, an electrode and a wire, the power supply is arranged on the outer surface of the desolventizing tank body, and the electrode is electrically connected with the power supply through the wire; the heating assembly comprises a liquid collecting pipe and a heating pipe, one end of the liquid collecting pipe is connected with the desolventizing bin, and the heating pipe is arranged in the containing cavity in the circumferential direction of the liquid collecting pipe; and the recovery assembly is connected with the heating assembly. The heating component and the pulse generating component which are used for assisting desolvation are arranged in the desolvation tank body to be matched with the desolvation component to concentrate and purify centella asiatica, so that the working efficiency of purifying the total glycosides of the centella asiatica is improved.

Description

Technical Field

[0001] This utility model relates to the technical field of plant component extraction equipment, and in particular to a device for concentrating and purifying total glycosides from Centella asiatica. Background Technology

[0002] Centella asiatica, also known as iron lamp grass, horse hoof grass, and thunder root, is a perennial herb belonging to the Apiaceae family. Its main medicinal value lies in treating damp-heat jaundice, carbuncles, boils, and traumatic injuries. The pharmacologically active components of Centella asiatica are mainly saponins and their aglycones, including asiaticoside, asiaticoside, hydroxyasiaticoside, and hydroxyasiaticoside, collectively referred to as total asiatic glycosides. The extraction and purification of total asiatic glycosides has always been a key focus of Centella asiatica research.

[0003] Existing concentration equipment has certain drawbacks in use, such as: large losses during purification, low working efficiency, low output, and inability to carry out large-scale operations.

[0004] Therefore, there is a need for a concentration and purification device for total asiatic acid glycosides that can improve the efficiency of the extraction process. Utility Model Content

[0005] The main purpose of this invention is to provide a device for concentrating and purifying total glycosides from Centella asiatica, which aims to solve the problem of low efficiency in the existing extraction process of total glycosides from Centella asiatica.

[0006] To achieve the above objectives, the present invention provides a device for concentrating and purifying total glycosides of Centella asiatica, comprising:

[0007] A desolvation tank, wherein a cavity is provided inside the desolvation tank;

[0008] A solvent removal assembly is disposed at the top of the accommodating cavity. The solvent removal assembly includes a solvent removal chamber, a feeding section, and a liquid inlet section. One end of the feeding section and one end of the liquid inlet section pass through the solvent removal tank and are respectively connected to the solvent removal chamber.

[0009] A pulse generating assembly includes a power supply, electrodes, and wires. The power supply is disposed on the outer surface of the desolvation tank. One end of the electrode passes through the desolvation chamber, and the other end of the electrode is electrically connected to the power supply through the wires.

[0010] A heating assembly, comprising a liquid collecting pipe and a heating pipe, wherein one end of the liquid collecting pipe is connected to the desolvation chamber, and the heating pipe is arranged circumferentially around the liquid collecting pipe in the receiving cavity;

[0011] A recovery component is disposed at one end of the receiving cavity and away from the desolvation component, and the recovery component is connected to the heating component.

[0012] Preferably, the liquid collecting pipe includes a converging pipe and a straight pipe, one end of the converging pipe is connected to the desolvation chamber, the other end of the converging pipe is connected to the straight pipe, and the heating pipe is arranged around the circumference of the straight pipe.

[0013] Preferably, the recovery assembly includes a liquid collection tank, a liquid outlet pipe, and a liquid outlet valve. The liquid collection tank is located at the bottom of the receiving cavity, and a through hole is provided at the top of the liquid collection tank. The liquid collection tank is connected to the straight pipe through the through hole. The liquid outlet pipe is located at the bottom of the liquid collection tank, and one end of the liquid outlet pipe passes through the desolvation tank. The liquid outlet valve is located at the end of the liquid outlet pipe away from the desolvation tank.

[0014] Preferably, the heating assembly further includes a heat circulation pipe, a heat medium inlet, and a heat medium outlet. The heat circulation pipe is arranged circumferentially along the liquid accumulation tank in the desolvation tank. One end of the heat circulation pipe is connected to the heat medium inlet, and the other end of the heat circulation pipe is connected to the heat medium outlet. The heat medium inlet and the heat medium outlet are spaced apart in the desolvation tank.

[0015] Preferably, the desolventizing assembly includes an vent pipe, which is disposed at the top of the desolventizing tank and one end of the vent pipe passes through the desolventizing chamber.

[0016] Preferably, the pulse generating assembly further includes a protective cover, which is disposed inside the desolvation chamber and covers one end of the electrode, and the bottom of the protective cover has a liquid passage hole.

[0017] Preferably, the pulse generating assembly further includes a temperature sensor, which is disposed on the inner wall of the desolvation tank and connected to the protective cover, and one end of the temperature sensor is connected to the electrode through the wire.

[0018] This invention incorporates a pulse generator and a heating element within the desolvation tank. The pulse generator applies an electric field to the tank, enhancing the dissolution and extraction efficiency of total asiaticoside by the solvent. Simultaneously, the heating element raises the temperature of the solvent, increasing the molecular velocity within the solution, shortening the extraction time, and improving the solubility of total asiaticoside. This results in increased extraction efficiency, reduced extraction losses, and improved overall efficiency of the total asiaticoside extraction process. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0020] Figure 1 This is a schematic diagram of the structure of a device for concentrating and purifying total glycosides of Centella asiatica according to an embodiment of the present invention;

[0021] Figure 2 This is a schematic cross-sectional view of total glycosides from Centella asiatica according to an embodiment of the present invention.

[0022] Figure 3 This is a front cross-sectional view of a desolvation component according to an embodiment of the present invention.

[0023] Figure 4 This is a front cross-sectional view of a heating assembly according to an embodiment of the present invention.

[0024] Figure 5 This is a front cross-sectional view of a recycling component according to an embodiment of the present invention.

[0025] Explanation of icon numbers:

[0026] label name label name 1000 Concentration and purification device for total glycosides of Centella asiatica 100 Desolventizing tank 200 Desolventizing components 210 Desolventization chamber 220 Feeding section 230 Liquid entry part 240 air outlet 300 Pulse Generator Component 310 power supply 320 electrode 330 Protective shield 340 Temperature sensor 400 Heating components 410 Collection tube 411 tapered tube 412 Straight pipe 420 heating element 430 Hot circulation pipes 440 Heat Media Entry 450 Thermal media export 500 Recycled components 510 Liquid storage tank 520 Discharge tube 530 Discharge valve

[0027] The realization of the purpose, functional features and advantages of this utility model will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] It should be noted that all directional indicators in this embodiment are only used to explain the relative positional relationship and movement of the components in a specific posture. If the specific posture changes, the directional indicator will also change accordingly.

[0030] Furthermore, the use of terms such as "first" and "second" in this utility model is for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. Additionally, the technical solutions of the various embodiments can be combined with each other, but only on the basis of being achievable by those skilled in the art. When the combination of technical solutions is contradictory or impossible to implement, such a combination of technical solutions should be considered non-existent and not within the scope of protection claimed by this utility model.

[0031] This utility model proposes a concentration and purification device 1000 for total glycosides of Centella asiatica, comprising: a desolvation tank 100, the desolvation tank 100 having a cavity; a desolvation assembly 200, the desolvation assembly 200 being disposed at the top of the cavity, the desolvation assembly 200 including a desolvation chamber 210, a feed section 220 and a liquid inlet section 230, one end of the feed section 220 and the liquid inlet section 230 passing through the desolvation tank 100 and respectively connected to the desolvation chamber 210; and a pulse generation assembly 300, the pulse generation assembly 300 including a power supply 310, an electrode 320 and wires, the power supply... Electrode 320 is disposed on the outer surface of the desolvation tank 100. One end of electrode 320 is inserted into the desolvation chamber 210, and the other end of electrode 320 is electrically connected to power supply 310 via a wire. Heating assembly 400 includes a liquid collecting pipe 410 and a heating pipe 420. One end of the liquid collecting pipe 410 is connected to the desolvation chamber 210, and the heating pipe 420 is arranged circumferentially around the liquid collecting pipe 410 in the receiving cavity. Recovery assembly 500 is disposed in the receiving cavity and away from one end of the desolvation assembly 200. Recovery assembly 500 is connected to heating assembly 400.

[0032] In this embodiment, as Figures 1-4As shown, the desolvation tank 100 contains a desolvation assembly 200, a heating assembly 400, and a recovery assembly 500 connected sequentially from top to bottom within its accommodating cavity. The desolvation assembly 200 includes a desolvation chamber 210, which is a solid with a cavity. The cavity within the desolvation chamber 210 is the desolvation space, which is connected to the external environment via a feed section 220 or a liquid inlet section 230. The desolvation space is used to extract total asiaticoside from Centella asiatica. A pulse generator assembly 300 is located within the desolvation space. By applying an electric field, it increases the polarity of the solvent, enhancing the solubility of total asiaticoside from Centella asiatica, thereby accelerating the extraction process. The liquid collection pipe 410 of the heating assembly 400 has a cavity inside, which is the heating space. The heating space is connected to the desolvation space and is used to heat the extract of total asiaticoside from Centella asiatica, causing the extract to spontaneously concentrate and purify. The recovery component 500 is located at the bottom of the desolvation tank 100. The recovery component 500 has a recovery space inside, which is connected to the heating space. The recovery space is used to collect the concentrated extract of total glycosides of Centella asiatica obtained after multiple extractions.

[0033] In detail, the operator turns on the heating component 400, causing the heating tube 420 to heat the collection tube 410. When the temperature inside the collection tube 410 rises to the set threshold (determined according to the specific desolvation solvent used; for example, if water is used as the desolvation solvent, the threshold is 90-100℃; if ethanol is used, the threshold is 60-80℃; in this embodiment, ethanol is used as the desolvation solvent, so the threshold is set to 60-80℃), when the temperature inside the collection tube 410 reaches the lower limit of the set threshold, the Centella asiatica material is fed into the desolvation chamber 210 through the feed section 220. Then, a 70% concentration ethanol solution is used as the desolvation solvent and fed into the desolvation space through the liquid inlet section 230. The 70% concentration ethanol can effectively dissolve and extract the total asiaticosides from the Centella asiatica, completing the preliminary extraction process.

[0034] The pulse generation assembly 300 may also include a temperature control system and a discharge tube. The power supply 310, temperature control system, discharge tube, and electrode 320 are connected by wires. The power supply 310 provides stable voltage and current to generate the required electric field. The temperature control system monitors and regulates the temperature during the extraction process to prevent overheating from affecting the extraction effect. The discharge tube serves as an effective protection measure to prevent short circuits and accidental discharges, and helps control the discharge of electrode 320, thereby protecting electrode 320 and the equipment, especially ensuring the safety of electrode 320 under high voltage and high current conditions.

[0035] During the extraction of total asiaticosides, the heating tube 420 continuously heats the collecting tube 410 to the upper limit of the set threshold and then maintains the temperature. The pulse generator 300 continuously releases an electric field to the mixed solution, promoting the dissolution and release of total asiaticosides. During the preliminary extraction process, the solvent falls freely into the collecting tube 410 due to gravity. Since the temperature in the collecting tube 410 reaches the evaporation temperature of ethanol, the ethanol vapor flows back from bottom to top in the collecting tube 410, causing the asiaticoside extract after the preliminary extraction to return to the desolvation chamber 210 for secondary desolvation. This achieves multiple reflux extraction of total asiaticosides, reducing purification losses.

[0036] In one embodiment, the liquid collection pipe 410 includes a tapered pipe 411 and a straight pipe 412. One end of the tapered pipe 411 is connected to the desolvation chamber 210, and the other end of the tapered pipe 411 is connected to the straight pipe 412. The heating pipe 420 is arranged circumferentially around the straight pipe 412.

[0037] In detail, the converging tube 411 in the collecting tube 410 is an inverted hollow frustum. The diameter of the end of the converging tube 411 near the desolvation chamber 210 is larger than the diameter of the end away from the desolvation chamber 210, i.e., the converging tube 411 is a funnel-shaped tube to increase the heating area. The interior of the converging tube 411 is connected to the desolvation space, and a filter screen is provided at the end of the converging tube 411 near the desolvation chamber 210. The desolvation chamber 210 is also equipped with a corresponding filter screen to isolate the material and prevent the material from flowing out of the desolvation chamber 210 with the extract. One end of the straight tube 412 is connected to the end of the converging tube 411 away from the desolvation chamber 210, and the other end of the straight tube 412 is connected to the recovery component 500. The straight tube 412 is used to guide the extract to the recovery component 500. A heating tube 420 is arranged to surround the tapered tube 411 and the straight tube 412. The heating tube 420 is used to heat the tapered tube 411 and the straight tube 412 to form steam of the extract. The steam rises from bottom to top, driving the extract to flow back upward for further purification.

[0038] In one embodiment, the recovery assembly 500 includes a liquid collection tank 510, a liquid outlet pipe 520, and a liquid outlet valve 530. The liquid collection tank 510 is located at the bottom of the cavity, and a through hole is provided at the top of the liquid collection tank 510. The liquid collection tank 510 is connected to a straight pipe 412 through the through hole. The liquid outlet pipe 520 is located at the bottom of the liquid collection tank 510, and one end of the liquid outlet pipe 520 passes through the desolvation tank 100. The liquid outlet valve 530 is located at the end of the liquid outlet pipe 520 away from the desolvation tank 100.

[0039] In detail, the liquid collection tank 510 has a recovery space inside. A through-hole is provided at the top of the liquid collection tank 510, and the recovery space is connected to the space inside the straight pipe 412 through the through-hole. This allows the concentrated total glycosides of Centella asiatica, after multiple purifications, to flow downwards from the desolvation space into the recovery space through the converging pipe 411 and the straight pipe 412. An outlet pipe 520 is provided at the bottom of the liquid collection tank 510, connecting the liquid collection tank 510 to the external environment. An outlet valve 530 is located at one end of the outlet pipe 520, allowing the operator to control the flow of the concentrated liquid from the outlet pipe 520.

[0040] In one embodiment, the heating assembly 400 further includes a heat circulation pipe 430, a heat medium inlet 440, and a heat medium outlet 450. The heat circulation pipe 430 is arranged circumferentially along the liquid accumulation tank 510 in the desolvation tank 100. One end of the heat circulation pipe 430 is connected to the heat medium inlet 440, and the other end of the heat circulation pipe 430 is connected to the heat medium outlet 450. The heat medium inlet 440 and the heat medium outlet 450 are spaced apart in the desolvation tank 100.

[0041] In detail, the heat circulation pipe 430 is arranged circumferentially around the liquid collection tank 510 to heat the extract in the liquid collection tank 510, further concentrating the extract and removing the desolvation solvent. The heat medium inlet 440 and heat medium outlet 450 are respectively arranged at intervals on the desolvation tank 100 and are respectively connected to the two ends of the heat circulation pipe 430. A high-temperature heat medium is input into the heat circulation pipe 430 through the heat medium inlet 440, and after heat conduction into the liquid collection tank 510 through the heat circulation pipe 430, it becomes a lower-temperature heat medium, and then flows out from the heat medium outlet 450. In this embodiment, the heat medium can be selected as high-temperature steam. The high-temperature steam decreases in temperature after passing through the heat circulation pipe 430 to obtain condensate, which flows out from the heat medium outlet 450. Therefore, the height of the heat medium outlet 450 above the ground is lower than that of the heat medium inlet 440.

[0042] In one embodiment, the desolventizing assembly 200 includes an vent pipe 240, which is disposed at the top of the desolventizing tank 100 and one end of the vent pipe 240 passes through the desolventizing chamber 210.

[0043] Specifically, the vent pipe 240 is located at the top of the desolventizing chamber 210, connecting the desolventizing space to the external environment. When the material and solvent in the desolventizing chamber 210 are purified during heating, steam is inevitably generated after the heating process. When the internal pressure of the desolventizing tank 100 reaches a threshold, the operator can vent the steam through the vent pipe 240. It is understood that the vent can be connected to the heat medium inlet 440 to recycle the high-temperature steam.

[0044] In one embodiment, the pulse generating assembly 300 further includes a protective cover 330, which is disposed inside the desolvation chamber 210 and covers one end of the electrode 320. A liquid passage hole is provided at the bottom of the protective cover 330.

[0045] In detail, in this embodiment, the protective cover 330 is used to protect the electrode 320 from direct contact with the material, preventing the material from undergoing chemical changes due to being too close to the electrode 320 during discharge, which would affect the composition and purity of the extract. The electrode 320 contacts the extract through a liquid passage hole below the protective cover 330.

[0046] It is understandable that electrode 320 can enhance the dissolution and extraction efficiency of the target compound (total glycosides of Centella asiatica in this embodiment) by applying an electric field. By utilizing the effect of the electric field, the distribution and dissolution behavior of the components in the sample are changed. After the electric field is applied, the ions in the solvent move under the action of the electric field, forming a current, which causes the polar molecules in the solvent to align in the direction of the electric field, thereby enhancing its ability to dissolve non-polar or low-polar compounds.

[0047] In one embodiment, the pulse generating assembly 300 further includes a temperature sensor 340, which is disposed on the inner wall of the desolvation tank 100 and connected to the protective cover 330. One end of the temperature sensor 340 is connected to the electrode 320 via a wire.

[0048] In detail, the temperature sensor 340 is signal-connected to the electrode 320 and the heating tube 420. The temperature sensor 340 is used to obtain the temperature of the solution. When the temperature sensor 340 detects that the temperature has reached the lower limit of the set threshold, it transmits a start signal to the electrode 320, causing the electrode 320 to start discharging. When the temperature sensor 340 detects that the temperature has reached the upper limit of the set threshold, it transmits a stop signal to the heating tube 420, causing the heating tube 420 to stop heating. This protects the total asiaticoside from thermal decomposition while accelerating the release rate of the total asiaticoside.

[0049] This invention incorporates a desolvation component, a pulse generator, and a heating component within a desolvation tank for extracting asiaticoside. A recovery component then collects the concentrated total asiaticoside extract. Specifically, the pulse generator applies an electric field to the mixture of asiaticoside material, desolvation solvent, and asiaticoside extract within the desolvation tank, enhancing the dissolution and extraction efficiency of the desolvation solvent on the total asiaticoside. Simultaneously, the heating component raises the temperature of the solvent, significantly increasing the molecular velocity within the solution, shortening the extraction time, and improving the solubility of the total asiaticoside, thereby increasing extraction efficiency, reducing extraction losses, and improving the overall efficiency of the asiaticoside extraction process.

[0050] The above description is only a preferred embodiment of the present utility model and does not limit the patent scope of the present utility model. All equivalent structural transformations made under the concept of the present utility model and using the contents of the present utility model specification and drawings, or direct / indirect applications in other related technical fields, are included in the patent protection scope of the present utility model.

Claims

1. A device for concentrating and purifying total glycosides from Centella asiatica, characterized in that, include: A desolvation tank, wherein a cavity is provided inside the desolvation tank; A solvent removal assembly is disposed at the top of the accommodating cavity. The solvent removal assembly includes a solvent removal chamber, a feeding section, and a liquid inlet section. One end of the feeding section and one end of the liquid inlet section pass through the solvent removal tank and are respectively connected to the solvent removal chamber. A pulse generating assembly includes a power supply, electrodes, and wires. The power supply is disposed on the outer surface of the desolvation tank. One end of the electrode passes through the desolvation chamber, and the other end of the electrode is electrically connected to the power supply through the wires. A heating assembly, comprising a liquid collecting pipe and a heating pipe, wherein one end of the liquid collecting pipe is connected to the desolvation chamber, and the heating pipe is arranged circumferentially around the liquid collecting pipe in the receiving cavity; A recovery component is disposed at one end of the receiving cavity and away from the desolvation component, and the recovery component is connected to the heating component.

2. The apparatus for concentrating and purifying total glycosides of Centella asiatica as described in claim 1, characterized in that, The liquid collection tube includes a converging tube and a straight tube. One end of the converging tube is connected to the desolvation chamber, and the other end of the converging tube is connected to the straight tube. The heating tube is arranged circumferentially around the straight tube.

3. The apparatus for concentrating and purifying total glycosides of Centella asiatica as described in claim 2, characterized in that, The recovery assembly includes a liquid collection tank, a liquid outlet pipe, and a liquid outlet valve. The liquid collection tank is located at the bottom of the receiving cavity, and a through hole is provided at the top of the liquid collection tank. The liquid collection tank is connected to the straight pipe through the through hole. The liquid outlet pipe is located at the bottom of the liquid collection tank, and one end of the liquid outlet pipe passes through the desolvation tank. The liquid outlet valve is located at the end of the liquid outlet pipe away from the desolvation tank.

4. The apparatus for concentrating and purifying total glycosides of Centella asiatica as described in claim 3, characterized in that, The heating assembly further includes a heat circulation pipe, a heat medium inlet, and a heat medium outlet. The heat circulation pipe is arranged circumferentially along the liquid accumulation tank in the desolvation tank. One end of the heat circulation pipe is connected to the heat medium inlet, and the other end of the heat circulation pipe is connected to the heat medium outlet. The heat medium inlet and the heat medium outlet are spaced apart in the desolvation tank.

5. The apparatus for concentrating and purifying total glycosides of Centella asiatica as described in claim 4, characterized in that, The desolventizing assembly includes an vent pipe, which is located at the top of the desolventizing tank and one end of the vent pipe passes through the desolventizing chamber.

6. The apparatus for concentrating and purifying total glycosides of Centella asiatica as described in claim 1, characterized in that, The pulse generating assembly also includes a protective cover, which is disposed inside the desolvation chamber and covers one end of the electrode. The bottom of the protective cover has a liquid passage hole.

7. The apparatus for concentrating and purifying total glycosides of Centella asiatica as described in claim 6, characterized in that, The pulse generating assembly also includes a temperature sensor, which is disposed on the inner wall of the desolvation tank and connected to the protective cover. One end of the temperature sensor is connected to the electrode through the wire.

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