Preparation mixing device for lomustine capsule production
By designing a mixing device consisting of spiral blades, a stirring rack, and a transmission system, the problem of insufficient mixing in the production of lomustine capsules was solved, achieving efficient mixing and discharge, and improving production efficiency.
Patent Information
- Application Number
- CN202422864691.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-25
- Publication Date
- 2025-10-31
- Estimated Expiration
- 2034-11-25
AI Technical Summary
In the existing technology, the rotation range of the mixing device is limited during the production of lomustine capsules, which results in the drug not being fully mixed at corner positions, affecting production efficiency.
A mixing device comprising a mixing component and a discharging component was designed. The mixing component achieves comprehensive tumbling and mixing through spiral blades, a stirring frame, and a transmission system. The discharging component achieves thorough mixing and discharge by driving the rotation of the moving frame and the mixing tank with a motor.
The design of the dispensing component enables thorough mixing of raw materials during the production of lomustine capsules, improving mixing efficiency. It also achieves efficient formulation dispensing, thereby enhancing production efficiency.
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Figure CN223490812U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of capsule production technology, specifically a formulation mixing device for the production of lomustine capsules. Background Technology
[0002] Lomustine is an alkylated drug commonly used to treat diseases such as melanoma, glioblastoma, and leukemia. The production of lomustine involves multiple steps, including raw material preparation, compound synthesis, purification and crystallization, quality control, and packaging. Among these, formulation mixing is a crucial step in the production process, as it affects the quality and stability of the final product.
[0003] A search revealed a utility model patent with Chinese patent publication number CN220143157U, which discloses a capsule raw material mixing device, relating to the field of capsule production and processing technology. The device includes a mixing box, and the outside of the mixing box is provided with a mixing and cleaning mechanism. The mixing and cleaning mechanism includes a servo motor mounted on the upper surface of the mixing box, and a planar gear is fixedly connected to the output shaft end of the servo motor. A conveying pipe is rotatably connected to the inner wall of the mixing box.
[0004] The above-mentioned device mixes the reagents by means of a stirring plate with a dispersing hole. However, due to its limited rotation range, the reagents located at the corners of the mixing box cannot be moved. Therefore, it takes longer to achieve the ideal mixing effect, which is inconvenient and hinders the improvement of production efficiency. Utility Model Content
[0005] The purpose of this invention is to provide a formulation mixing device for the production of lomustine capsules, so as to solve the problems mentioned in the background art.
[0006] To achieve the above objectives, this utility model provides the following technical solution: a formulation mixing device for the production of lomustine capsules, comprising a mounting base, a mixing component mounted on the top of the mounting base, the mixing component including a movable frame placed on the inner wall of the bottom of the mounting base, a mixing tank rotatably connected to the inner circumference of the movable frame via bearings, a plurality of equally spaced spiral blades fixedly connected to the inner circumference of the mixing tank, a can lid rotatably connected to the inside of the mounting base via bearings, and the can lid being able to completely seal the opening of the mixing tank, a plurality of equally spaced transmission rods fixedly connected to the inner wall of one side of the can lid, and a through hole adapted to the transmission rods being opened inside the mixing tank.
[0007] As a further preferred embodiment of this technical solution, the can lid is rotatably connected to the center of the can lid via a bearing. Multiple sets of equally spaced stirring racks are rotatably connected to the inner circumference of the can lid. Each set of stirring racks consists of three equally spaced stirring racks. A motor is fixedly installed on the inner bottom wall of the mounting base. A transmission gear is coaxially fixed to the output end of the motor. A gear ring is coaxially fixed to one side of the outer wall of the can lid. The transmission gear meshes with the gear ring. A pulley is fixedly fitted on both the output end of the motor and the outer circumference of the can lid. The two pulleys are fitted with the same belt.
[0008] As a further preferred embodiment of this technical solution, an installation shaft is fixedly connected to the inner wall of one side of the mounting base, and one end of the installation shaft is rotatably connected to the inner wall of one side of the mounting tube through a bearing. Multiple helical gears I are coaxially fixed to the outer circumference of the installation shaft. A helical gear II is coaxially fixed to the end of each of the multiple sets of stirring racks that are close to each other, and the multiple sets of helical gears II respectively mesh with multiple helical gears I.
[0009] This system allows all the raw materials inside the mixing tank to flow, resulting in more thorough mixing. With the cooperation of multiple stirring racks, mixing efficiency is greatly improved. Starting the motor at the bottom of the mounting base drives a transmission gear and a pulley to rotate clockwise. This drives a gear ring to rotate counter-clockwise, causing the tank lid to rotate synchronously. The tank lid, through multiple transmission rods, drives the mixing tank to rotate inside the moving frame. Under the action of multiple spiral blades, the various raw materials are tumbled. The bottom pulley, via a belt, drives another pulley to rotate synchronously, causing the mounting tube to rotate clockwise. Multiple externally extending stirring racks then begin mixing the raw materials. During the revolution of the stirring racks, the helical gears at their ends, meshing with the fixed helical gears outside the mounting shaft, rotate on their own axis, further increasing mixing efficiency.
[0010] As a further preferred embodiment of this technical solution, two discharge assemblies are installed inside the mounting base, and the two discharge assemblies are respectively located at both ends of the movable frame.
[0011] As a further preferred embodiment of this technical solution, the discharge assembly includes two support plates fixedly connected to one end of the inner wall of the bottom of the mounting base. The two support plates are rotatably connected to the same lead screw through a bearing. A connecting column is threaded onto the outside of the lead screw. One end of the connecting column is fixedly connected to the movable frame. A second motor is fixedly installed on one side of the outer wall of one of the support plates. The output end of the second motor is coaxially fixed with one end of the lead screw.
[0012] The second motor outside the support plate is started, and its output drives the lead screw to rotate. With the cooperation and drive of the two lead screws, the moving frame can be moved to one side through the two connecting columns. At this time, the can lid and the mixing tank will also have a gap, and the preparation will slide out from the gap. Since the transmission rod is still inserted in the through hole of the mixing tank, the can lid and the transmission rod are driven to drive the mixing tank to rotate clockwise, and the spiral blades can completely discharge the preparation to the outside.
[0013] As a further preferred embodiment of this technical solution, two rollers are rotatably connected to the outer walls of both ends of the mobile frame, and all four rollers are in contact with the inner wall of the bottom of the mounting base.
[0014] As a further preferred embodiment of this technical solution, the transmission ratio between the bottom pulley and the top pulley is greater than one.
[0015] This invention provides a formulation mixing device for the production of lomustine capsules, which has the following beneficial effects:
[0016] (1) By setting up a mixing component, this utility model enables all the raw materials inside the mixing tank to flow, thereby making the raw materials more thoroughly mixed. With the cooperation of multiple stirring racks, the mixing efficiency can be greatly improved. Start the motor at the bottom of the mounting base to drive the transmission gear and a pulley to rotate clockwise. Through meshing, the gear ring rotates counterclockwise, and the tank cover will also be driven to rotate synchronously. The tank cover drives the mixing tank to rotate inside the moving frame through multiple transmission rods. Under the action of multiple spiral blades, various raw materials will be driven to tumble. The pulley at the bottom can drive another pulley to rotate synchronously through the belt, and the mounting tube will be driven to rotate clockwise. The multiple stirring racks extending from its outside can start to stir the raw materials. When the stirring rack revolves, the helical gear at its end will rotate on its own axis under the meshing of the helical gear fixed outside the mounting shaft, which can further increase the mixing efficiency.
[0017] (2) By setting up a discharge assembly, the second motor outside the support plate is started, and its output end drives the lead screw to rotate. Under the cooperation and drive of the two lead screws, the moving frame can be moved to one side through the two connecting columns. At this time, the can lid and the mixing tank will also have a gap, and the preparation will slide out from the gap. Since the transmission rod is still inserted in the through hole of the mixing tank, the can lid and the transmission rod are driven to drive the mixing tank to rotate clockwise, and the spiral blades can completely discharge the preparation to the outside. Attached Figure Description
[0018] Figure 1 This is a schematic diagram of the overall first-view structure of this utility model;
[0019] Figure 2 This is a schematic diagram of the overall second-view structure of this utility model;
[0020] Figure 3 This is an enlarged structural schematic diagram of the mixing tank of this utility model;
[0021] Figure 4 This is a partially enlarged structural diagram of the hybrid component of this utility model;
[0022] In the diagram: 1. Mounting base; 2. Roller; 3. Mixing component; 4. Discharge component; 301. Moving frame; 303. Mixing tank; 304. Tank cover; 305. Transmission rod; 306. Spiral blade; 307. Motor 1; 308. Transmission gear; 309. Gear ring; 310. Pulley; 311. Belt; 312. Mounting shaft; 313. Mixing rack; 314. Mounting pipe; 401. Support plate; 402. Motor 2; 403. Lead screw; 404. Connecting column. Detailed Implementation
[0023] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.
[0024] This utility model provides a technical solution: such as Figure 2 , Figure 3 and Figure 4 As shown in this embodiment, a formulation mixing device for the production of lomustine capsules includes a mounting base 1. A mixing component 3 is mounted on the top of the mounting base 1. The mixing component 3 includes a movable frame 301 placed on the inner wall of the bottom of the mounting base 1. A mixing tank 303 is rotatably connected to the inner circumference of the movable frame 301 via bearings. A plurality of equally spaced spiral blades 306 are fixedly connected to the inner circumference of the mixing tank 303. A can lid 304 is rotatably connected to the inside of the mounting base 1 via bearings. The can lid 304 can completely seal the opening of the mixing tank 303. A plurality of equally spaced transmission rods 305 are fixedly connected to the inner wall of one side of the can lid 304. A through hole adapted to the transmission rods 305 is opened inside the mixing tank 303.
[0025] The can lid 304 is rotatably connected to the middle of the can lid 304 via a bearing. Multiple sets of equally spaced stirring racks 313 are rotatably connected to the inner circumference of the can lid 304. Each set of stirring racks 313 consists of three equally spaced stirring racks 313. A motor 307 is fixedly installed on the inner bottom wall of the mounting base 1. A transmission gear 308 is coaxially fixed to the output end of the motor 307. A gear ring 309 is coaxially fixed to one side of the outer wall of the can lid 304. The transmission gear 308 meshes with the gear ring 309. A pulley 310 is fixedly fitted on both the output end of the motor 307 and the outer circumference of the can lid 304. The two pulleys 310 are fitted with the same belt 311.
[0026] A mounting shaft 312 is fixedly connected to the inner wall of one side of the mounting base 1, and one end of the mounting shaft 312 is rotatably connected to the inner wall of one side of the mounting tube 314 through a bearing. Multiple helical gears 1 are coaxially fixed on the outer circumference of the mounting shaft 312. A helical gear 2 is coaxially fixed at the end of each of the multiple sets of stirring racks 313 that are close to each other, and the multiple sets of helical gears 2 mesh with multiple helical gears 1 respectively.
[0027] The motor 307 at the bottom of the mounting base 1 is started, which drives the transmission gear 308 and a pulley 310 to rotate clockwise. Through meshing, the gear ring 309 rotates counterclockwise, and the can lid 304 is also driven to rotate synchronously. The can lid 304 drives the mixing tank 303 to rotate inside the moving frame 301 through multiple transmission rods 305. Under the action of multiple spiral blades 306, various raw materials are driven to tumble, so that the raw materials are mixed thoroughly. The bottom pulley 310 drives another pulley 310 to rotate synchronously through the belt 311, and the mounting tube 314 is driven to rotate clockwise. The multiple stirring racks 313 extending from its outside can start to stir the raw materials. When the stirring rack 313 revolves, the helical gear at its end will rotate on its own axis under the meshing of the helical gear fixed outside the mounting shaft 312, which can further increase the mixing efficiency.
[0028] like Figure 1 and Figure 2 As shown, two material discharge components 4 are installed inside the mounting base 1. The two material discharge components 4 are located at both ends of the movable frame 301. The two material discharge components 4 work together to ensure that the movement of the movable frame 301 is stable enough.
[0029] The material discharge assembly 4 includes two support plates 401 fixedly connected to one end of the bottom inner wall of the mounting base 1. The two support plates 401 are rotatably connected to the same lead screw 403 through a bearing. The lead screw 403 is threaded with a connecting post 404. One end of the connecting post 404 is fixedly connected to the movable frame 301. A second motor 402 is fixedly installed on one side outer wall of one of the support plates 401. The output end of the second motor 402 is coaxially fixed with one end of the lead screw 403.
[0030] The motor 402 outside the support plate 401 is started, and its output drives the lead screw 403 to rotate. With the cooperation and drive of the two lead screws 403, the moving frame 301 can be moved to one side through the two connecting columns 404. At this time, the can lid 304 and the mixing tank 303 will also have a gap, and the preparation will slide out from the gap. Since the transmission rod 305 is still inserted in the through hole of the mixing tank 303, the can lid 304 and the transmission rod 305 are driven to drive the mixing tank 303 to rotate clockwise, and the spiral blade 306 can completely discharge the preparation to the outside.
[0031] like Figure 1 and Figure 2 As shown, two rollers 2 are rotatably connected to the outer walls of both ends of the movable frame 301. All four rollers 2 are in contact with the inner wall of the bottom of the mounting base 1. Under the action of the rollers 2, the sliding friction between the movable frame 301 and the mounting base 1 can be transformed into rolling friction, which helps to reduce the load on the motor 402.
[0032] like Figure 4 As shown, the transmission ratio between the bottom pulley 310 and the top pulley 310 is greater than one. The bottom pulley 310 needs to rotate many times to drive the top pulley 310 to rotate once, which makes the load on the motor 307 less when it is driven.
[0033] This invention provides a formulation mixing device for the production of lomustine capsules, the specific working principle of which is as follows:
[0034] When the device is in operation, the sealing plate at the end of the mixing tank 303 is opened, and then the raw materials for preparing the reagent are put into it. The motor 307 at the bottom of the mounting base 1 is started, which drives the transmission gear 308 and a pulley 310 to rotate clockwise. Through meshing, the gear ring 309 rotates counterclockwise, and the tank cover 304 is also driven to rotate synchronously. The tank cover 304 drives the mixing tank 303 to rotate inside the moving frame 301 through multiple transmission rods 305. Under the action of multiple spiral blades 306, the various raw materials are driven to tumble, so that the raw materials are mixed thoroughly. The pulley 310 at the bottom drives another pulley 310 to rotate synchronously through the belt 311, and then the mounting tube 314 is driven to rotate clockwise. The multiple stirring racks 313 extending from its outside are then... The mixing of raw materials can begin. When the mixing rack 313 revolves, the helical gear at its end, under the meshing of the helical gear fixed outside the mounting shaft 312, will rotate during the revolution, which can further increase the mixing efficiency. In this way, the motor 402 outside the support plate 401 is started, and its output end drives the lead screw 403 to rotate. Under the cooperation and drive of the two lead screws 403, it can drive the moving frame 301 to one side through the two connecting columns 404. At this time, the can lid 304 and the mixing tank 303 will also have a gap, and the preparation will slide out from the gap. Since the transmission rod 305 is still inserted in the through hole of the mixing tank 303, the can lid 304 and the transmission rod 305 are driven to drive the mixing tank 303 to rotate clockwise, and the spiral blades 306 can completely discharge the preparation to the outside.
[0035] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A formulation mixing apparatus for the production of lomustine capsules, comprising a mounting base (1), characterized in that: The top of the mounting base (1) is equipped with a mixing component (3). The mixing component (3) includes a movable frame (301) placed on the inner wall of the bottom of the mounting base (1). The inner circumference of the movable frame (301) is rotatably connected to a mixing tank (303) via a bearing. The inner circumference of the mixing tank (303) is fixedly connected with a plurality of equally spaced spiral blades (306). The inside of the mounting base (1) is rotatably connected to a tank cover (304) via a bearing. The tank cover (304) can completely seal the opening of the mixing tank (303). The inner wall of one side of the tank cover (304) is fixedly connected with a plurality of equally spaced transmission rods (305). The inside of the mixing tank (303) is provided with through holes adapted to the transmission rods (305).
2. The formulation mixing apparatus for producing lomustine capsules according to claim 1, characterized in that: The can lid (304) is rotatably connected to the middle of the can lid (304) via a bearing. Multiple sets of equally spaced stirring racks (313) are rotatably connected to the inner circumference of the can lid (304). Each set of stirring racks (313) consists of three equally spaced stirring racks (313). A motor (307) is fixedly installed on the inner bottom wall of the mounting base (1). A transmission gear (308) is coaxially fixed to the output end of the motor (307). A gear ring (309) is coaxially fixed to one side of the outer wall of the can lid (304). The transmission gear (308) meshes with the gear ring (309). A pulley (310) is fixedly fitted on both the output end of the motor (307) and the outer circumference of the can lid (304). The two pulleys (310) are fitted with the same belt (311).
3. A formulation mixing apparatus for the production of lomustine capsules according to claim 2, characterized in that: The mounting base (1) is fixedly connected to the inner wall of one side of the mounting shaft (312), and one end of the mounting shaft (312) is rotatably connected to the inner wall of the mounting tube (314) through a bearing. Multiple helical gears I are coaxially fixed on the outer circumference of the mounting shaft (312). Multiple sets of stirring racks (313) are coaxially fixed with a helical gear II at their close ends, and multiple sets of helical gear II mesh with multiple helical gears I respectively.
4. A formulation mixing apparatus for the production of lomustine capsules according to claim 1, characterized in that: The mounting base (1) has two discharge components (4) installed inside, and the two discharge components (4) are located at both ends of the movable frame (301).
5. A formulation mixing apparatus for the production of lomustine capsules according to claim 4, characterized in that: The discharge assembly (4) includes two support plates (401) fixedly connected to one end of the bottom inner wall of the mounting base (1). The two support plates (401) are rotatably connected by the same lead screw (403) through a bearing. The lead screw (403) is threaded with a connecting column (404). One end of the connecting column (404) is fixedly connected to the moving frame (301). A second motor (402) is fixedly installed on one side outer wall of one of the support plates (401). The output end of the second motor (402) is coaxially fixed with one end of the lead screw (403).
6. A formulation mixing apparatus for the production of lomustine capsules according to claim 1, characterized in that: The movable frame (301) has two rollers (2) rotatably connected to the outer walls at both ends, and all four rollers (2) are in contact with the bottom inner wall of the mounting base (1).
7. A formulation mixing apparatus for the production of lomustine capsules according to claim 2, characterized in that: The transmission ratio between the bottom pulley (310) and the top pulley (310) is greater than one.
Citation Information
Patent Citations
Capsule raw material mixing device
CN220143157U