Optical fiber adjusting mechanism on flow cytometer

Abstract

The utility model relates to the technical field of optical fiber processing applied to a multi-laser flow cytometer, in particular to an optical fiber adjusting mechanism on a flow cytometer. The first adjusting assembly drives the optical fiber support to slide on the installation groove so as to adjust the position of the optical fiber support in the first direction, the second adjusting assembly drives the base to adjust the position of the base in the second direction, the first direction is perpendicular to the second direction, and the third adjusting assembly drives the optical fiber body to rotate on the positioning hole so as to adjust the angle of the optical fiber body. Through the adjustment, the front-back distance and the left-right distance of the optical fiber body can be adjusted relative to the optical platform, the optical fiber holes can be vertically arranged through adjustment, it can be guaranteed that the optical fibers are arranged in a line in the vertical direction according to the optical path design result, and a certain distance is kept between the upper portion and the lower portion of each optical fiber.

Description

Technical Field

[0001] The utility model relates to the field of optical fiber processing technology applied in multi-laser flow cytometers, and relates to an optical fiber adjustment mechanism on a flow cytometer. Background Technology

[0002] A flow cytometer is an instrument used for rapid and accurate analysis and sorting of cells. It uses a laser as a light source to illuminate fluorescently stained sample cells in a flow chamber, generating scattered light and exciting fluorescence. These signals are typically transmitted via fiber optic cable to a photoelectric detection module, which converts the scattered light and fluorescence signals into electrical signals. After amplification and data processing, sample information can be obtained.

[0003] For flow cytometers that use multiple lasers, multiple laser beams of different wavelengths are usually shaped and combined before irradiating sample cells. The multiple laser beams after being combined are usually arranged in the vertical direction. The scattered light and excitation fluorescence generated after different lasers irradiate the sample cells are injected into different optical fibers arranged at a certain distance in the vertical direction.

[0004] Due to manufacturing errors in the optical fiber and installation device, scattered light and fluorescence cannot accurately enter the optical fiber, thus affecting the detection of phototube signals. Existing optical fiber adjustment devices are not flexible enough in adjusting the position of the optical fiber during use, and the overall flexibility and adjustability of the device need to be improved. Therefore, an optical fiber adjustment mechanism for flow cytometers is needed. Utility Model Content

[0005] The technical problem to be solved by this utility model is to provide an optical fiber adjustment mechanism for a flow cytometer that allows the optical fiber body to be adjusted in front-back and left-right distances, and can adjust the optical fiber holes to be arranged vertically, ensuring that the optical fibers are arranged in a straight line vertically.

[0006] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is as follows:

[0007] A fiber optic adjustment mechanism for a flow cytometer includes:

[0008] The base has a mounting slot.

[0009] An optical fiber assembly is disposed on the mounting groove. The optical fiber assembly includes an optical fiber bracket. A pressure plate is disposed on the base. The optical fiber bracket is pressed into the mounting groove by the pressure plate. A positioning hole is disposed on the optical fiber bracket. An optical fiber body is disposed on the positioning hole. An optical fiber through hole for inserting an optical fiber is opened on the optical fiber body.

[0010] A first adjustment component is disposed on the pressure plate and connected to the optical fiber support. The first adjustment component is used to drive the optical fiber support to slide on the mounting groove to adjust its position in a first direction.

[0011] The second adjustment component is connected to the base and is used to drive the base to adjust its position along the second direction, wherein the first direction is perpendicular to the second direction.

[0012] The third adjustment component is disposed on the optical fiber support and is connected to the optical fiber body. The third adjustment component is used to drive the optical fiber body to rotate on the positioning hole to adjust its angle.

[0013] In one embodiment of this utility model, a positioning groove is provided on the bottom surface of the mounting groove, the inclined surfaces on both sides of the positioning groove are arranged in a V-shape, and the optical fiber bracket has an arc surface, which abuts against the two inclined surfaces for positioning.

[0014] In one embodiment of this utility model, the optical fiber body has a columnar structure, and the cross-sectional diameter of the optical fiber body is less than or equal to the diameter of the positioning hole. The optical fiber support is provided with a fixing hole, which is connected to the mounting groove. A fixing screw is provided on the fixing hole, and the fixing screw is used to fix the optical fiber body to the optical fiber support.

[0015] In one embodiment of this utility model, the top of the optical fiber bracket is provided with a flat surface, the top of the base is provided with a mounting end face, the pressure plate is connected to the mounting end face by mounting bolts, and the height of the flat surface is higher than the height of the mounting end face, so that there is a mounting gap between the pressure plate and the mounting end face.

[0016] In one embodiment of the present invention, the first adjustment component includes an adjustment frame and an adjustment screw. The two ends of the adjustment screw are rotated on the adjustment frame. An adjustment nut is provided on the adjustment screw. The adjustment nut is slidably disposed on the adjustment frame. A positioning rod is provided on the adjustment nut. The positioning rod is connected to the optical fiber support.

[0017] In one embodiment of this utility model, the optical fiber support is provided with an adjustment groove, the two adjustment inclined surfaces on both sides of the adjustment groove are V-shaped, the free end of the positioning rod is spherical, and the free end of the positioning rod is inserted into the adjustment groove.

[0018] In one embodiment of the present invention, the second adjusting component includes an adjusting frame, an adjusting screw is rotatably mounted on the adjusting frame, and a threaded hole is provided on the base, through which the adjusting screw passes.

[0019] In one embodiment of this utility model, a waist-shaped groove is provided on the bottom surface of the base, and the length direction of the waist-shaped groove is parallel to the axis of the adjusting screw.

[0020] In one embodiment of this utility model, the third adjustment component includes two adjustment screws, the optical fiber support has two adjustment screw holes, the optical fiber body has an adjustment plane, the adjustment screws pass through the adjustment screw holes and abut against the adjustment plane, and by rotating one or two adjustment screws, the adjustment plane on the optical fiber body is pushed, thereby causing the optical fiber body to rotate on the positioning hole.

[0021] In one embodiment of this utility model, a fixed protrusion is provided on the optical fiber body, an optical fiber end face is provided on the fixed protrusion, and an optical fiber through hole is provided on the optical fiber end face.

[0022] The beneficial effects of this utility model are:

[0023] The first adjustment component of this utility model drives the fiber optic bracket to slide on the mounting groove to adjust its position in the first direction. The second adjustment component drives the base to adjust its position along the second direction. The first direction is perpendicular to the second direction. The third adjustment component drives the fiber optic body to rotate on the positioning hole to adjust its angle. Through the above adjustments, the fiber optic body can be adjusted in front and back, left and right relative to the optical platform, and the fiber optic holes can be adjusted to be vertically aligned. This ensures that the fiber optics are arranged in a straight line according to the optical path design, and that each fiber optic is kept at a certain distance from the top to the bottom. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of an optical fiber adjustment mechanism on a flow cytometer according to the present invention.

[0025] Figure 2 This is a schematic diagram of the first adjustment component of this utility model.

[0026] Figure 3 This is an exploded schematic diagram of this utility model.

[0027] Figure 4 This is a schematic diagram of the base of this utility model.

[0028] The following are the labeling symbols in the diagram: 1. Base; 11. Mounting slot; 12. Positioning slot; 13. Waist-shaped slot; 2. Fiber optic bracket; 21. Positioning hole; 22. Plane; 23. Fixing hole; 24. Fixing screw; 3. Fiber optic body; 31. Fixing protrusion; 32. Fiber optic end face; 33. Fiber optic through hole; 4. Third adjustment component; 41. Adjustment plane; 42. Adjustment screw; 43. Adjustment screw hole; 5. Pressure plate; 51. Mounting bolt; 6. First adjustment component; 61. Adjustment frame; 62. Section screw; 63. Adjustment nut; 64. Positioning rod; 65. Adjustment slot; 7. Second adjustment component; 71. Adjustment frame; 72. Adjustment screw. Detailed Implementation

[0029] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments are not intended to limit the present invention.

[0030] Reference Figure 1-4 As shown, an optical fiber adjustment mechanism for a flow cytometer includes:

[0031] Base 1, on which a mounting slot 11 is provided;

[0032] An optical fiber assembly is disposed on the mounting groove 11. The optical fiber assembly includes an optical fiber support 2. A pressure plate 5 is disposed on the base 1. The optical fiber support 2 is pressed into the mounting groove 11 by the pressure plate 5. The optical fiber support 2 is provided with a positioning hole 21. An optical fiber body 3 is disposed on the positioning hole 21. An optical fiber through hole 33 for inserting optical fiber is opened on the optical fiber body 3.

[0033] The first adjustment component 6 is disposed on the pressure plate 5. The first adjustment component 6 is connected to the optical fiber bracket 2. The first adjustment component 6 is used to drive the optical fiber bracket 2 to slide on the mounting groove 11 to adjust its position in the first direction.

[0034] The second adjustment component 7 is connected to the base 1. The second adjustment component 7 is used to drive the base 1 to adjust its position along the second direction, where the first direction is perpendicular to the second direction.

[0035] The third adjustment component 4 is disposed on the optical fiber support 2. The third adjustment component 4 is connected to the optical fiber body 3. The third adjustment component 4 is used to drive the optical fiber body 3 to rotate on the positioning hole 21 to adjust its angle.

[0036] The first adjustment component 6 of this invention drives the fiber optic bracket 2 to slide on the mounting groove 11 to adjust its position in the first direction. The second adjustment component 7 drives the base 1 to adjust its position along the second direction. The first direction is perpendicular to the second direction. The third adjustment component 4 drives the fiber optic body 3 to rotate on the positioning hole 21 to adjust its angle. Through the above adjustments, the fiber optic body 3 can be adjusted in front and back, and left and right relative to the optical platform. It can also be adjusted so that one or more fiber optic holes are arranged vertically. This ensures that the optical fibers are arranged vertically in a straight line according to the optical path design results, and that each fiber is kept at a certain distance from the top and bottom. This improves the adjustability of the device, ensures the accurate collection of optical signals in the optical system, and meets the usage requirements of different optical path design systems.

[0037] In one embodiment of the present invention, a positioning groove 12 is provided on the bottom surface of the mounting groove 11, the inclined surfaces on both sides of the positioning groove 12 are arranged in a V-shape, and the optical fiber bracket 2 has an arc surface, which abuts against the two inclined surfaces for positioning.

[0038] Specifically, the arc surface and the two inclined surfaces abut and position each other, so that the positioning groove 12 effectively supports the fiber optic bracket 2 while ensuring the distance between the fiber optic and the optical platform, thus ensuring the installation accuracy of the entire mechanism.

[0039] In one embodiment of this utility model, the optical fiber body 3 has a columnar structure, and the cross-sectional diameter of the optical fiber body 3 is less than or equal to the diameter of the positioning hole 21. The optical fiber support 2 is provided with a fixing hole 23, which is connected to the mounting groove 11. A fixing screw 24 is provided on the fixing hole 23, and the fixing screw 24 is used to fix the optical fiber body 3 to the optical fiber support 2.

[0040] Specifically, the cross-sectional diameter of the fiber body 3 is less than or equal to the diameter of the positioning hole 21, so that the fiber body 3 can rotate relative to the positioning hole 21. After the fiber body 3 is inserted into the fiber support 2 for position adjustment, it is tightened by the fixing screw 24 to ensure that the multiple fiber through holes 33 on the fiber body 3 are always perpendicular, which can ensure that the fiber is arranged in a straight line according to the optical path design result, and ensure the fiber installation accuracy.

[0041] In one embodiment of this utility model, the top of the optical fiber bracket 2 is provided with a plane 22, the top of the base 1 is provided with an installation end face, the pressure plate 5 is connected to the installation end face by mounting bolts 51, and the height of the plane 22 is higher than the height of the installation end face, so that there is an installation gap between the pressure plate 5 and the installation end face.

[0042] Specifically, the height of plane 22 is higher than the height of the mounting end face. After the fiber optic bracket 2 is pressed, there is an installation gap between the pressure plate 5 and the mounting end face. Tighten the four mounting bolts 51, and the pressure plate 5 presses the fiber optic bracket 2 to make the fiber optic bracket 2 secure. The top of the fiber optic bracket 2 is provided with a plane 22, which increases the contact area between the pressure plate 5 and the fiber optic body 3, so that the fiber optic body 3 can be pressed more tightly and is not easy to slip.

[0043] In one embodiment of the present invention, the first adjustment component 6 includes an adjustment frame 61 and an adjustment screw 62. The two ends of the adjustment screw 62 are rotated on the adjustment frame 61. An adjustment nut 63 is provided on the adjustment screw 62. The adjustment nut 63 is slidably mounted on the adjustment frame 61. A positioning rod 64 is provided on the adjustment nut 63. The positioning rod 64 is connected to the optical fiber bracket 2.

[0044] Specifically, loosening the mounting bolts 51 on the pressure plate 5 creates a certain adjustment gap between the pressure plate 5 and the plane 22. Rotating the adjusting screw 62 causes the adjusting nut 63 on it to drive the positioning rod 64 to move along the adjusting frame 61, so that the positioning rod 64 can pull the fiber optic bracket 2 and the fiber optic body 3 to make fine adjustments in the front-back direction (first direction), allowing the scattered light to accurately enter the fiber optic cable and ensuring installation accuracy.

[0045] In one embodiment of this utility model, the optical fiber support 2 is provided with an adjustment groove 65, the two adjustment inclined surfaces on both sides of the adjustment groove 65 are V-shaped, the free end of the positioning rod 64 is spherical, and the free end of the positioning rod 64 is inserted into the adjustment groove 65.

[0046] Specifically, the upper end of the fiber optic bracket 2 has a V-shaped adjustment groove 65, and the free end of the positioning rod 64 has a spherical structure. The positioning rod 64 can be inserted into the V-shaped adjustment groove 65. The positioning rod 64 is always pressed against the two adjustment inclined surfaces, which can accurately adjust the position of the fiber optic bracket 2, avoid adjustment play, and ensure adjustment accuracy.

[0047] In one embodiment of this utility model, the second adjustment component 7 includes an adjustment frame 71, on which an adjustment screw 72 is rotatably mounted. The base 1 is provided with a threaded hole, and the adjustment screw 72 passes through the threaded hole. Rotating the adjustment screw 72 can finely adjust the position of the base 1 to ensure the accuracy of the fiber optic installation.

[0048] In one embodiment of the present invention, a waist-shaped groove 13 is provided on the bottom surface of the base 1, and the length direction of the waist-shaped groove 13 is parallel to the axis of the adjusting screw 72.

[0049] Specifically, the base 1 is placed on the mounting platform, which is equipped with a limiting pin that matches the waist-shaped groove 13. The waist-shaped groove 13 on the base 1 is fitted onto the limiting pin. The adjustment bracket 71 is placed on the mounting platform. The adjustment screw 72 is rotated to engage with the threaded hole of the adjustment screw 72, so that the waist-shaped groove 13 on the base 1 moves left and right along the limiting pin to adjust, which plays a guiding role for the base 1 and ensures the positional accuracy of the base 1 adjustment.

[0050] In one embodiment of the present invention, the third adjustment component 4 includes two adjustment screws 42, the optical fiber support 2 has two adjustment screw holes 43, the optical fiber body 3 has an adjustment plane 41, the adjustment screws 42 pass through the adjustment screw holes 43 and abut against the adjustment plane 41, and by rotating one or two adjustment screws 42, the adjustment plane 41 on the optical fiber body 3 is pushed, thereby driving the optical fiber body 3 to rotate on the positioning hole 21.

[0051] Specifically, the optical fiber body 3 has an adjustment plane 41, and the ends of the two adjustment screws 42 can abut against the adjustment plane 41. Since the two adjustment screws 42 press on both sides of the adjustment plane 41 respectively, by tightening one of the two adjustment screws 42 and loosening the other adjustment screw 42, the optical fiber body 3 can be adjusted counterclockwise or clockwise on the optical fiber support 2, so that the multiple optical fiber through holes 33 on the optical fiber body 3 are in a vertical state.

[0052] In one embodiment of the present invention, a fixed protrusion 31 is provided on the optical fiber body 3, an optical fiber end face 32 is provided on the fixed protrusion 31, and an optical fiber through hole 33 is provided on the optical fiber end face 32.

[0053] Specifically, since the fiber end face 32 needs to be flush, the end face is processed into a fixed protrusion 31 during processing. As long as the flatness and surface roughness of the fixed protrusion 31 are guaranteed, the processing difficulty is reduced. If there is no protrusion, the flatness and surface roughness of the entire surface must be guaranteed, which is difficult to guarantee during processing.

[0054] Usage process

[0055] Place the base 1 on the mounting platform. The mounting platform is equipped with a limiting pin that matches the waist-shaped groove 13. The waist-shaped groove 13 on the base 1 is fitted onto the limiting pin. The adjusting frame 71 is placed on the mounting platform. Rotate the adjusting screw 72 to engage the threaded hole of the adjusting screw 72, causing the waist-shaped groove 13 on the base 1 to move left and right along the limiting pin for adjustment. This guides the base 1 and ensures the positional accuracy of the base 1. After the left and right (second direction) adjustment is completed, tighten the connecting screws between the base 1 and the mounting platform. Loosen the mounting bolts 51 on the pressure plate 5 to create a certain adjustment gap between the pressure plate 5 and the plane 22. Rotate the adjusting screw 62 to cause the adjusting nut 63 on it to drive the positioning rod 64 to move along the adjusting frame 61, allowing the positioning rod 64 to pull the fiber optic bracket 2 and the fiber optic body 3 for fine adjustment in the front-back (first direction). The upper end of the fiber optic bracket 2 is the plane 22. When the fiber optic bracket 2 moves back and forth... When the adjustment is complete, tighten the four mounting bolts 51, and the pressure plate 5 presses the fiber optic bracket 2 to secure it. When the fiber optic body 3 is inserted into the fiber optic bracket 2, it is tightened by the fixing screw 24 and pressed by the pressure plate 5. The multiple fiber optic through holes 33 on the fiber optic body 3 may not be perpendicular. The fiber optic body 3 has an adjustment plane 41, and the ends of the two adjustment screws 42 can abut against the adjustment plane 41. Since the two adjustment screws 42 press on both sides of the adjustment plane 41 respectively, by tightening one of the two adjustment screws 42 and loosening the other adjustment screw 42, the fiber optic body 3 can be adjusted counterclockwise or clockwise on the fiber optic bracket 2. Through the above adjustment, the fiber optic body 3 can be adjusted in front and back, left and right relative to the optical platform, and the fiber holes can be adjusted to be vertically aligned. This ensures that the optical fibers are arranged in a straight line according to the optical path design, and that each fiber is kept at a certain distance from the top to the bottom.

[0056] The above-described embodiments are merely preferred embodiments provided to fully illustrate the present invention, and the scope of protection of the present invention is not limited thereto. Equivalent substitutions or modifications made by those skilled in the art based on the present invention are all within the scope of protection of the present invention. The scope of protection of the present invention is defined by the claims.

Claims

1. An optical fiber adjustment mechanism for a flow cytometer, characterized in that, include: The base has a mounting slot. An optical fiber assembly is disposed on the mounting groove. The optical fiber assembly includes an optical fiber bracket. A pressure plate is disposed on the base. The optical fiber bracket is pressed into the mounting groove by the pressure plate. A positioning hole is disposed on the optical fiber bracket. An optical fiber body is disposed on the positioning hole. An optical fiber through hole for inserting an optical fiber is opened on the optical fiber body. A first adjustment component is disposed on the pressure plate and connected to the optical fiber support. The first adjustment component is used to drive the optical fiber support to slide on the mounting groove to adjust its position in a first direction. The second adjustment component is connected to the base and is used to drive the base to adjust its position along the second direction, wherein the first direction is perpendicular to the second direction. The third adjustment component is disposed on the optical fiber support and is connected to the optical fiber body. The third adjustment component is used to drive the optical fiber body to rotate on the positioning hole to adjust its angle.

2. The fiber optic adjustment mechanism on the flow cytometer as described in claim 1, characterized in that, A positioning groove is provided on the bottom surface of the mounting groove, and the inclined surfaces on both sides of the positioning groove are arranged in a V-shape. The optical fiber bracket has an arc surface, and the arc surface abuts against the two inclined surfaces for positioning.

3. The fiber optic adjustment mechanism on the flow cytometer as described in claim 1, characterized in that, The optical fiber body has a columnar structure, and the cross-sectional diameter of the optical fiber body is less than or equal to the diameter of the positioning hole. The optical fiber support is provided with a fixing hole, which is connected to the mounting groove. A fixing screw is provided on the fixing hole, and the fixing screw is used to fix the optical fiber body to the optical fiber support.

4. The fiber optic adjustment mechanism on the flow cytometer as described in claim 1, characterized in that, The top of the fiber optic bracket has a flat surface, and the top of the base has a mounting end face. The pressure plate is connected to the mounting end face by mounting bolts. The height of the flat surface is higher than the height of the mounting end face, so that there is an installation gap between the pressure plate and the mounting end face.

5. The fiber optic adjustment mechanism on the flow cytometer as described in claim 1, characterized in that, The first adjustment assembly includes an adjustment frame and an adjustment screw. The two ends of the adjustment screw are mounted on the adjustment frame. An adjustment nut is provided on the adjustment screw and slides on the adjustment frame. A positioning rod is provided on the adjustment nut and is connected to the optical fiber support.

6. The fiber optic adjustment mechanism on a flow cytometer as described in claim 5, characterized in that, The fiber optic bracket has an adjustment groove, and the two adjustment ramps on both sides of the adjustment groove are V-shaped. The free end of the positioning rod is spherical and is inserted into the adjustment groove.

7. The fiber optic adjustment mechanism on a flow cytometer as described in claim 1, characterized in that, The second adjustment component includes an adjustment frame with an adjustment screw rotating on it, and a threaded hole on the base through which the adjustment screw passes.

8. The fiber optic adjustment mechanism on a flow cytometer as described in claim 7, characterized in that, The base has a waist-shaped groove on its bottom surface, and the length direction of the waist-shaped groove is parallel to the axis of the adjusting screw.

9. The fiber optic adjustment mechanism on a flow cytometer as described in claim 1, characterized in that, The third adjustment component includes two adjustment screws, the optical fiber support has two adjustment screw holes, the optical fiber body has an adjustment plane, the adjustment screws pass through the adjustment screw holes and abut against the adjustment plane, and by rotating one or two adjustment screws, the adjustment plane on the optical fiber body is pushed, thereby causing the optical fiber body to rotate on the positioning hole.

10. The fiber optic adjustment mechanism on a flow cytometer as described in claim 1, characterized in that, A fixed protrusion is provided on the optical fiber body, and an optical fiber end face is provided on the fixed protrusion. The optical fiber through hole is provided on the optical fiber end face.

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