Material preheating device for pharmaceutic adjuvant production

Abstract

The utility model relates to a material preheating device for pharmaceutic adjuvant production. The material preheating device comprises a mounting frame, a preheating conveying mechanism used for preheating the pharmaceutic adjuvants is arranged in the mounting frame; a treatment mechanism for pre-treating and crushing the pharmaceutic adjuvants is arranged at the top of the mounting frame, the pharmaceutic adjuvants are added into a treatment barrel through a feeding hopper, a first motor is started to drive a crushing rod to rotate, the pharmaceutic adjuvants in the treatment barrel are crushed, the crushed pharmaceutic adjuvants enter a conveying pipeline through a discharging valve pipe, a plurality of heating pipe fittings in a heating frame are started, and the pharmaceutic adjuvants enter the conveying pipeline; the conveying pipeline is heated, the crushed auxiliary materials enter the conveying pipeline to be heated, the second motor is started to drive the spiral conveying paddle to rotate, the auxiliary materials in the conveying pipeline are conveyed, and due to the fact that the auxiliary materials are preheated, long-time heating is not needed, and the auxiliary materials in the conveying pipeline are discharged through the discharging pipe along with rotation of the spiral conveying paddle; and for the pharmaceutic adjuvants which do not need to be crushed, the treatment barrel can be detached.

Description

Technical Field

[0001] This utility model relates to the technical field of pharmaceutical excipient production equipment, specifically a material preheating device for pharmaceutical excipient production. Background Technology

[0002] Pharmaceutical excipients refer to all pharmaceutical materials, other than the active pharmaceutical ingredient, added to a pharmaceutical formulation to address the formulation's shapeability, efficacy, stability, and safety during formulation design. The pharmaceutical formulation design process is essentially the screening and application of pharmaceutical excipients based on drug characteristics and dosage form requirements. Pharmaceutical excipients are fundamental materials and crucial components of pharmaceutical formulations, serving as the material basis for their production and development. They play a key role in formulation dosage forms and production. Currently, existing technologies lack the function of crushing pharmaceutical excipients before preheating. Without crushing, the excipient particles may be too large, leading to uneven heating. Larger particles may require longer heating times and higher energy consumption to ensure the excipients reach the required temperature, increasing production costs and placing an additional burden on equipment.

[0003] For example, the authorized patent document with application number CN202321666869.0 discloses a material preheating device for the production of pharmaceutical excipients, which relates to the field of waste treatment technology. It includes a box body, with support legs fixedly connected to the four corners of the bottom of the box body. A feed inlet is provided at the right position of the top of the box body. A motor is fixedly installed at the center of the top of the box body. The output end of the motor passes through the top of the box body and is fixedly connected to the rotating shaft. Several stirring blades are fixedly connected to the surface of the rotating shaft. A fixing block is fixedly connected to the inner side wall of the box body.

[0004] The aforementioned patent has the problem that the excipient particles are too large, which may require longer heating time and higher energy consumption to ensure that the excipients reach the required temperature. This not only increases production costs but may also put an extra burden on the equipment. Therefore, we need to provide a material preheating device for the production of pharmaceutical excipients. Utility Model Content

[0005] The purpose of this invention is to provide a material preheating device for pharmaceutical excipient production. A processing mechanism is set above the preheating conveying mechanism to crush the pharmaceutical excipients, increase the specific surface area of ​​the material, and make the pharmaceutical excipients easier to dissolve and mix evenly during preheating and subsequent processing. The excipient particles are smaller, the required heating time is shortened, and less energy is consumed to reach the required temperature, thus solving the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a material preheating device for pharmaceutical excipient production, comprising:

[0007] Mounting rack;

[0008] The mounting frame is equipped with a preheating conveying mechanism for preheating pharmaceutical excipients.

[0009] The top of the mounting frame is equipped with a processing mechanism for pre-processing and crushing pharmaceutical excipients.

[0010] Preferably, the processing mechanism includes a processing barrel disposed on the top of the mounting frame, a first motor mounted on the top of the processing barrel, a crushing rod mounted on the output end of the first motor, a discharge valve pipe connected to the bottom of the processing barrel, a feed hopper connected to the top of the processing barrel, and an installation assembly for quick loading and unloading of the processing barrel disposed on the top of the mounting frame.

[0011] Preferably, the mounting assembly includes a ring body fixedly mounted on the surface of the processing tank. The ring body has two slots inside, and each slot is fitted with a limit buckle. Support columns are fixedly mounted at the four corners of the bottom of the ring body.

[0012] Preferably, a fixing ring is fixedly installed at the bottom of the two limiting buckles, the top of the fixing ring is in contact with the bottom of the four support columns, and a bending member for bending the two limiting buckles is installed at the top of the fixing ring.

[0013] Preferably, the bending member includes two fixing plates fixedly installed on the top of the fixing ring, and each of the two fixing plates is threaded with an adjusting screw, which is used to bend by abutting the limiting buckle.

[0014] Preferably, the preheating conveying mechanism includes a heating frame disposed at the bottom of the inner wall of the mounting frame, a plurality of heating pipes are installed inside the heating frame, a conveying pipe is fixedly installed on the top of the heating frame, a discharge device for conveying auxiliary materials after crushing is rotatably installed inside the conveying pipe, a feed pipe connected to a discharge valve pipe is connected to the top of the conveying pipe, and a discharge pipe is connected to the bottom of the conveying pipe.

[0015] Preferably, the discharge component includes a spiral conveyor paddle rotatably installed inside the conveying pipe, and a second motor is installed on one side of the spiral conveyor paddle.

[0016] Preferably, two alignment blocks are fixedly installed on the top of the fixing ring, and an alignment groove is provided inside the ring body to cooperate with the two alignment blocks.

[0017] Compared with the prior art, the beneficial effects of this utility model are:

[0018] This invention features a processing mechanism above the preheating conveying mechanism to crush pharmaceutical excipients, increasing the specific surface area of ​​the material. This makes the pharmaceutical excipients easier to dissolve and mix evenly during preheating and subsequent processing. The excipient particles are smaller, requiring less heating time and less energy to reach the required temperature. Attached Figure Description

[0019] Figure 1 This is a three-dimensional structural schematic diagram of the present invention;

[0020] Figure 2 This is a perspective view of the discharge component of this utility model;

[0021] Figure 3 This is a perspective view of the installation components of this utility model;

[0022] Figure 4 This is a three-dimensional sectional view of the processing bucket of this utility model.

[0023] In the diagram: 1. Mounting frame; 2. Preheating conveying mechanism; 21. Heating frame; 22. Heating fittings; 23. Conveying pipe; 24. Discharge component; 241. Screw conveyor; 242. Second motor; 25. Feed pipe; 26. Discharge pipe; 3. Processing mechanism; 31. Processing tank; 32. First motor; 33. Crushing rod; 34. Discharge valve pipe; 35. Feed hopper; 30. Mounting assembly; 301. Ring body; 302. Slot; 303. Limiting buckle; 304. Support column; 4. Fixing ring; 5. Bending component; 51. Fixing plate; 52. Adjusting screw; 6. Alignment block; 7. Alignment groove. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figure 1-4 This utility model provides a technical solution: a material preheating device for pharmaceutical excipient production, comprising:

[0026] Mounting bracket 1;

[0027] The mounting frame 1 is equipped with a preheating conveying mechanism 2 for preheating pharmaceutical excipients;

[0028] The top of the mounting frame 1 is equipped with a processing mechanism 3 for pre-processing and crushing pharmaceutical excipients;

[0029] Specifically, a processing unit 3 is set above the preheating conveying mechanism 2 to crush the pharmaceutical excipients, increase the specific surface area of ​​the material, and make the pharmaceutical excipients easier to dissolve and mix evenly during preheating and subsequent processing. The excipient particles are smaller, the required heating time is shortened, and less energy is consumed to make the excipients reach the required temperature.

[0030] The processing mechanism 3 includes a processing barrel 31 set on the top of the mounting frame 1, a first motor 32 installed on the top of the processing barrel 31, a crushing rod 33 installed on the output end of the first motor 32, a discharge valve pipe 34 connected to the bottom of the processing barrel 31, a feed hopper 35 connected to the top of the processing barrel 31, and an installation assembly 30 for quick loading and unloading of the processing barrel 31 set on the top of the mounting frame 1.

[0031] In this embodiment, pharmaceutical excipients are added into the processing tank 31 through the feed hopper 35. The first motor 32 is started to drive the crushing rod 33 to rotate, crushing the pharmaceutical excipients in the processing tank 31. The excipients enter the conveying pipe 23 through the discharge valve pipe 34. Several heating pipes 22 in the heating frame 21 are started to heat the conveying pipe 23. The crushed excipients enter the conveying pipe 23 for heating. The second motor 242 is started to drive the spiral conveyor 241 to rotate, conveying the excipients in the conveying pipe 23. Since the excipients are preheated, there is no need for long-term heating. As the spiral conveyor 241 rotates, the excipients in the conveying pipe 23 are discharged through the discharge pipe 26.

[0032] For pharmaceutical excipients that do not require crushing, the processing bucket 31 can be removed. By rotating the two adjusting screws 52, the adjusting screws 52 will bend against the limiting buckle 303, preventing the limiting buckle 303 from engaging with the groove 302 inside the ring body 301. The processing bucket 31 can be removed using the handle on its surface. During installation, the groove 302 on the ring body 301 is directly engaged with the limiting buckle 303. Since the top of the limiting buckle 303 is sloping, the groove 302 is directly engaged with the limiting buckle 303. All four support columns 304 are located on the top of the fixed ring 4. After installation, the adjusting screws 52 generally will not contact the limiting buckle 303, except when the limiting buckle 303 is bent.

[0033] The mounting assembly 30 includes a ring 301 fixedly mounted on the surface of the processing tank 31. The ring 301 has two slots 302 inside, and each slot 302 is fitted with a limit buckle 303. Support columns 304 are fixedly mounted at the four corners of the bottom of the ring 301.

[0034] Specifically, during installation, the slot 302 on the ring body 301 is directly engaged with the limit buckle 303. Since the top of the limit buckle 303 is sloping, the slot 302 is directly engaged with the limit buckle 303 mechanism. All four support columns 304 are located on the top of the fixed ring 4, thus completing the installation.

[0035] A fixing ring 4 is fixedly installed at the bottom of the two limiting buckles 303. The top of the fixing ring 4 is in contact with the bottom of the four support columns 304, and a bending piece 5 for bending the two limiting buckles 303 is installed at the top of the fixing ring 4.

[0036] Furthermore, four support columns 304 are attached to the fixing ring 4 to support the processing barrel 31.

[0037] The bending component 5 includes two fixing plates 51 fixedly installed on the top of the fixing ring 4. Each of the two fixing plates 51 is threaded with an adjusting screw 52. The adjusting screw is used to bend by contacting the limit buckle 303.

[0038] For pharmaceutical excipients that do not require crushing, the processing bucket 31 can be removed. By rotating the two adjusting screws 52, the adjusting screws 52 will bend against the limiting buckle 303, so that the limiting buckle 303 is not engaged with the inner groove 302 of the ring body 301. The processing bucket 31 can then be removed using the handle on its surface.

[0039] The preheating conveying mechanism 2 includes a heating frame 21 set at the bottom of the inner wall of the mounting frame 1. Several heating pipes 22 are installed inside the heating frame 21. A conveying pipe 23 is fixedly installed on the top of the heating frame 21. A discharge device 24 for conveying auxiliary materials after crushing is rotatably installed inside the conveying pipe 23. The top of the conveying pipe 23 is connected to an inlet pipe 25 connected to a discharge valve pipe 34. The bottom of the conveying pipe 23 is connected to a discharge pipe 26.

[0040] It should be noted that the heating elements 22 inside the heating frame 21 are activated to heat the conveying pipe 23. The crushed auxiliary material enters the conveying pipe 23 for heating, and the second motor 242 is activated to drive the screw conveyor 241 to rotate and convey the auxiliary material in the conveying pipe 23. Since the auxiliary material is preheated, it does not need to be heated for a long time. As the screw conveyor 241 rotates, the auxiliary material in the conveying pipe 23 is discharged through the discharge pipe 26.

[0041] The discharge component 24 includes a spiral conveyor 241 rotatably installed in the conveying pipe 23, and a second motor 242 is installed on one side of the spiral conveyor 241;

[0042] Specifically, the second motor 242 is started to drive the screw conveyor 241 to rotate, and the auxiliary materials in the conveying pipe 23 are conveyed.

[0043] Two alignment blocks 6 are fixedly installed on the top of the fixed ring 4, and alignment grooves 7 are opened inside the ring body 301 to cooperate with the two alignment blocks 6.

[0044] To facilitate the positioning and engagement of the card slot 302 and the limit buckle 303, an alignment block 6 is provided on the fixed ring 4, and an alignment groove 7 is provided on the ring body 301. The alignment block 6 and the alignment groove 7 are used in conjunction.

[0045] This device feeds pharmaceutical excipients into the processing tank 31 through the feed hopper 35. The first motor 32 is started to drive the crushing rod 33 to rotate, crushing the pharmaceutical excipients in the processing tank 31. The crushed excipients then enter the conveying pipe 23 through the discharge valve pipe 34. Several heating pipes 22 in the heating frame 21 are activated to heat the conveying pipe 23. The crushed excipients enter the conveying pipe 23 for heating. The second motor 242 is started to drive the screw conveyor 241 to rotate, conveying the excipients in the conveying pipe 23. Since the excipients are preheated, there is no need for long-term heating. As the screw conveyor 241 rotates, the excipients in the conveying pipe 23 are discharged through the discharge pipe 26.

[0046] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A material preheating device for the production of pharmaceutical excipients, characterized in that, include: Mounting bracket (1); The mounting frame (1) is equipped with a preheating conveying mechanism (2) for preheating pharmaceutical excipients. The top of the mounting frame (1) is provided with a processing mechanism (3) for pre-processing and crushing pharmaceutical excipients.

2. The material preheating device for pharmaceutical excipient production according to claim 1, characterized in that: The processing mechanism (3) includes a processing barrel (31) set on the top of the mounting frame (1), a first motor (32) is installed on the top of the processing barrel (31), a crushing rod (33) is installed at the output end of the first motor (32), a discharge valve pipe (34) is connected to the bottom of the processing barrel (31), a feed hopper (35) is connected to the top of the processing barrel (31), and an installation assembly (30) for quick loading and unloading of the processing barrel (31) is set on the top of the mounting frame (1).

3. The material preheating device for pharmaceutical excipient production according to claim 2, characterized in that: The installation assembly (30) includes a ring (301) fixedly installed on the surface of the processing tank (31). The ring (301) has two slots (302) inside, and each slot (302) is fitted with a limit buckle (303). Support columns (304) are fixedly installed at the four corners of the bottom of the ring (301).

4. The material preheating device for pharmaceutical excipient production according to claim 3, characterized in that: A fixing ring (4) is fixedly installed at the bottom of the two limiting buckles (303). The top of the fixing ring (4) is in contact with the bottom of the four support columns (304), and a bending member (5) for bending the two limiting buckles (303) is installed at the top of the fixing ring (4).

5. A material preheating device for pharmaceutical excipient production according to claim 4, characterized in that: The bending member (5) includes two fixing plates (51) fixedly installed on the top of the fixing ring (4). The two fixing plates (51) are threaded with adjusting screws (52) inside. The adjusting screws are used to bend against the limiting buckle (303).

6. A material preheating device for pharmaceutical excipient production according to claim 5, characterized in that: The preheating conveying mechanism (2) includes a heating frame (21) set at the bottom of the inner wall of the mounting frame (1). Several heating pipes (22) are installed inside the heating frame (21). A conveying pipe (23) is fixedly installed on the top of the heating frame (21). A discharge device (24) for conveying auxiliary materials after crushing is rotatably installed inside the conveying pipe (23). The top of the conveying pipe (23) is connected to a feed pipe (25) connected to a discharge valve pipe (34). The bottom of the conveying pipe (23) is connected to a discharge pipe (26).

7. A material preheating device for pharmaceutical excipient production according to claim 6, characterized in that: The discharge component (24) includes a spiral conveyor (241) rotatably installed in the conveying pipe (23), and a second motor (242) is installed on one side of the spiral conveyor (241).

8. A material preheating device for pharmaceutical excipient production according to claim 7, characterized in that: Two alignment blocks (6) are fixedly installed on the top of the fixed ring (4), and alignment grooves (7) are opened inside the ring body (301) to cooperate with the two alignment blocks (6).

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