Glycosylated hemoglobin detection device

Abstract

The utility model relates to the technical field of medical detection devices, and discloses a glycosylated hemoglobin detection device, which comprises a sampling mechanism, a detection mechanism and a control mechanism, the sampling mechanism comprises an injection pump set, a sampling needle and a sampling valve, the sampling valve is a six-way sampling valve, the injection pump set is connected with a first port of the sampling valve, and the sampling needle is connected with a second port of the sampling valve; the separation mechanism comprises an eluent group, a mixer and a chromatographic separator, the eluent group is connected with a fifth port of the sample injection valve, the chromatographic separator is connected with a sixth port of the sample injection valve, and two ends of the mixer are connected with a third port and a fourth port of the sample injection valve; the inspection mechanism comprises a filter and an inspector, the filter is arranged between the mixer and the chromatographic separator, and the inspector is connected with the chromatographic separator. According to the utility model, the glycosylated hemoglobin can be rapidly and accurately detected through an accurate sample introduction and separation mechanism, so that the detection efficiency is improved. The automation degree of the detection process is high, the requirement for manual operation is reduced, and the possibility of human errors is reduced.

Description

Technical Field

[0001] This utility model relates to the field of medical testing device technology, and in particular to a glycated hemoglobin testing device. Background Technology

[0002] With the rising global incidence of diabetes, glycated hemoglobin (HbA1c) testing has become a crucial indicator for assessing diabetes control. Traditional HbA1c testing methods require sample elution, but these methods are often manual, resulting in complex procedures, long testing times, and high labor costs, failing to meet the clinical demand for rapid, accurate, and convenient testing. Therefore, developing a novel HbA1c detection device is of great significance for improving the diagnosis and treatment of diabetes. Utility Model Content

[0003] The purpose of this invention is to provide a glycated hemoglobin detection device to solve the above-mentioned problems.

[0004] This utility model provides a glycated hemoglobin detection device, comprising:

[0005] The injection mechanism includes an injection pump assembly, an injection needle, and an injection valve. The injection valve is a six-way injection valve. The injection pump assembly is connected to the first port of the injection valve, and the injection needle is connected to the second port of the injection valve.

[0006] The separation mechanism includes an eluent assembly, a mixer, and a chromatography separator. The eluent assembly is connected to the fifth port of the injection valve, the chromatography separator is connected to the sixth port of the injection valve, and the two ends of the mixer are connected to the third and fourth ports of the injection valve.

[0007] The testing apparatus includes a filter and a tester, the filter being disposed between the mixer and the chromatography separator, and the tester being connected to the chromatography separator.

[0008] Preferably, the injection pump assembly includes a first injection pump, a second injection pump, and an injection valve. The first injection pump is connected to the injection valve, the second injection pump is connected to the injection valve, and the injection valve is connected to the first port of the injection valve.

[0009] Preferably, the eluent assembly includes a first eluent storage tank, a second eluent storage tank, a first separation pump, and a second separation pump. The first eluent storage tank is connected to the first separation pump, the first separation pump is connected to the injection valve, the second eluent storage tank is connected to the second separation pump, and the second separation pump is connected to the injection valve.

[0010] Preferably, the separation mechanism further includes a separation valve, which is disposed between the injection valve and the first separation pump, and between the injection valve and the second separation pump.

[0011] Preferably, the mixer includes a mixing tank, a stirring shaft, a temperature sensor, and a heater. The stirring shaft is installed inside the mixing tank and is used to stir and mix the liquid in the mixing tank. The temperature sensor is located inside the mixing tank and is used to detect the temperature of the liquid in the mixing tank. The heater is located on the side wall of the mixing tank and is used to heat the liquid in the mixing tank.

[0012] Preferably, the glycated hemoglobin detection device further includes a waste liquid tank, which is connected to the detector via a waste liquid collection valve.

[0013] Preferably, a sample pool is provided at the bottom of the injection needle.

[0014] Preferably, an injection pump is provided between the injection needle and the injection valve.

[0015] Preferably, the detector is connected to a display device, which is used to display the detection results.

[0016] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0017] 1. This utility model, through the cooperation of a six-way injection valve and an injection pump assembly, achieves precise control of the injection volume, improving the accuracy and repeatability of the detection. The design of the separation mechanism effectively improves the separation purity and efficiency of glycated hemoglobin. The filters and detectors in the testing mechanism ensure the accuracy and reliability of the test results.

[0018] 2. The optimized design of the mixer, through the cooperation of the stirring shaft, temperature sensor and heater, ensures the uniformity of the mixture and temperature control, thereby improving the reaction efficiency.

[0019] 3. Through precise sample introduction and separation mechanisms, glycated hemoglobin detection can be completed quickly and accurately, improving detection efficiency. The combination of chromatographic separation technology and testing institutions ensures the accuracy of test results, helping doctors make correct diagnoses. The entire testing process is highly automated, reducing the need for manual operation and lowering the possibility of human error. Attached Figure Description

[0020] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0021] Figure 1 This is a schematic diagram of the structure of a glycated hemoglobin detection device according to the present invention;

[0022] Figure 2 This is a schematic diagram of the mixer in an embodiment of the present invention.

[0023] The components include: 1. Injection needle; 11. Sample cell; 12. Injection pump; 2. Injection valve; 21. First port; 22. Second port; 23. Third port; 24. Fourth port; 25. Fifth port; 26. Sixth port; 3. Injection valve; 31. First injection pump; 32. Second injection pump; 4. Mixer; 41. Mixing tank; 42. Stirring shaft; 43. Temperature sensor; 44. Heater; 5. Chromatography separator; 6. Filter; 7. Tester; 8. Separation valve; 81. First eluent tank; 82. Second eluent tank; 83. First separation pump; 84. Second separation pump; 9. Waste liquid tank; 91. Waste liquid collection valve; 10. Display device. Detailed Implementation

[0024] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.

[0025] In the description of this application, it should be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0026] The terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this application, unless otherwise stated, "a plurality of" means two or more.

[0027] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0028] like Figures 1-2 As shown, this utility model provides a glycated hemoglobin detection device, comprising:

[0029] The injection mechanism includes an injection pump assembly, an injection needle 1, and an injection valve 2. The injection valve 2 is a six-way injection valve 2. The injection pump assembly is connected to the first port 21 of the injection valve 2, and the injection needle 1 is connected to the second port 22 of the injection valve 2.

[0030] The separation mechanism includes an eluent group, a mixer 4, and a chromatography separator 5. The eluent group is connected to the fifth port 25 of the injection valve 2, the chromatography separator 5 is connected to the sixth port 26 of the injection valve 2, and the two ends of the mixer 4 are connected to the third port 23 and the fourth port 24 of the injection valve 2.

[0031] The testing mechanism includes a filter 6 and a tester 7. The filter 6 is located between the mixer 4 and the chromatography separator 5, and the tester 7 is connected to the chromatography separator 5.

[0032] In some embodiments of this application, the injection pump assembly includes a first injection pump 31, a second injection pump 32, and an injection valve 3. The first injection pump 31 is connected to the injection valve 3, the second injection pump 32 is connected to the injection valve 3, and the injection valve 3 is connected to the first port 21 of the injection valve 2.

[0033] The syringe pump set is equipped with multiple syringe pumps, which can be controlled according to the testing requirements to achieve the best testing results.

[0034] In some embodiments of this application, the eluent assembly includes a first eluent tank 81, a second eluent tank 82, a first separation pump 83, and a second separation pump 84. The first eluent tank 81 is connected to the first separation pump 83, the first separation pump 83 is connected to the injection valve 3, the second eluent tank 82 is connected to the second separation pump 84, and the second separation pump 84 is connected to the injection valve 3.

[0035] The first eluent storage tank 81 or the second eluent storage tank 82 is drawn by the first separation pump 83 and the second separation pump, and the eluent is delivered to the mixer 4. The presence of multiple corresponding eluent storage tanks and separation pumps ensures that the concentration of the eluent meets the testing requirements.

[0036] In some embodiments of this application, the separation mechanism further includes a separation valve 8, which is disposed between the injection valve 3 and the first separation pump 83, and between the injection valve 3 and the second separation pump 84.

[0037] In some embodiments of this application, the mixer 4 includes a mixing tank 41, a stirring shaft 42, a temperature sensor 43, and a heater 44. The stirring shaft 42 is installed inside the mixing tank 41 and is used to stir and mix the liquid in the mixing tank 41. The temperature sensor 43 is disposed inside the mixing tank 41 and is used to detect the temperature of the liquid in the mixing tank 41. The heater 44 is disposed on the side wall of the mixing tank 41 and is used to heat the liquid in the mixing tank 41.

[0038] By using a mixing tank 41, a stirring shaft 42, a temperature sensor 43, and a heater 44, efficient mixing of liquids is achieved. At the same time, the temperature of the mixed liquid can be accurately monitored and adjusted to ensure the uniformity of the heating process and maintain the required constant temperature of the mixed liquid.

[0039] In some embodiments of this application, the glycated hemoglobin detection device further includes a waste liquid tank 9, which is connected to the detector via a waste liquid collection valve 91.

[0040] Waste liquid generated during the testing process is collected by a waste liquid tank 9, ensuring a clean and safe experimental environment. During testing, after the detector completes the analysis of the sample, the waste liquid collection valve 91 opens, and the waste liquid flows into the waste liquid tank 9 through a connecting pipe. The waste liquid tank 9 is typically designed with sufficient capacity to store a certain amount of waste liquid and may be equipped with a level sensor to monitor the waste liquid level and alert operators to clean it when necessary. This design not only improves the automation level of the testing device but also reduces the opportunity for operators to have direct contact with waste liquid, lowering potential health risks.

[0041] In some embodiments of this application, a sample cell 11 is provided at the bottom of the injection needle 1. An injection pump 12 is provided between the injection needle 1 and the injection valve 2.

[0042] In some embodiments of this application, the detector is connected to a display device 10, which is used to display the detection results.

[0043] Once the detector has completed its detection of the sample, it converts the detection data into electronic signals and transmits them to the display device 10 via a connection cable or wirelessly. After receiving these signals, the display device 10 presents the detection results to the user in the form of numbers, charts, images, or other visualizations through a graphical user interface (GUI), so that the user can intuitively understand the detection results.

[0044] During testing, the injection needle 1 and the injection pump assembly control the blood sample to be delivered to the injection valve 2 through the first port 21 and the second port 22, and then into the mixer 4. At the same time, the eluent assembly controls the eluent to enter the mixer 4 through the fifth port 25. The mixer 4 mixes the test sample and then outputs the value detector through the fourth port 24 for testing.

[0045] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and not to limit it. Although the utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can still be made to the technical solution of this utility model, and these modifications or equivalent substitutions cannot cause the modified technical solution to deviate from the spirit and scope of the technical solution of this utility model.

Claims

1. A glycated hemoglobin detection device, characterized in that, include: The injection mechanism includes an injection pump assembly, an injection needle, and an injection valve. The injection valve is a six-way injection valve. The injection pump assembly is connected to the first port of the injection valve, and the injection needle is connected to the second port of the injection valve. The separation mechanism includes an eluent assembly, a mixer, and a chromatography separator. The eluent assembly is connected to the fifth port of the injection valve, the chromatography separator is connected to the sixth port of the injection valve, and the two ends of the mixer are connected to the third and fourth ports of the injection valve. The testing apparatus includes a filter and a tester, the filter being disposed between the mixer and the chromatography separator, and the tester being connected to the chromatography separator.

2. The glycated hemoglobin detection device according to claim 1, characterized in that, The injection pump assembly includes a first injection pump, a second injection pump, and an injection valve. The first injection pump is connected to the injection valve, the second injection pump is connected to the injection valve, and the injection valve is connected to the first port of the injection valve.

3. The glycated hemoglobin detection device according to claim 2, characterized in that, The eluent assembly includes a first eluent storage tank, a second eluent storage tank, a first separation pump, and a second separation pump. The first eluent storage tank is connected to the first separation pump, and the first separation pump is connected to the injection valve. The second eluent storage tank is connected to the second separation pump, and the second separation pump is connected to the injection valve.

4. The glycated hemoglobin detection device according to claim 3, characterized in that, The separation mechanism further includes a separation valve, which is disposed between the injection valve and the first separation pump, and between the injection valve and the second separation pump.

5. The glycated hemoglobin detection device according to claim 4, characterized in that, The mixer includes a mixing tank, a stirring shaft, a temperature sensor, and a heater. The stirring shaft is installed inside the mixing tank and is used to stir and mix the liquid in the mixing tank. The temperature sensor is located inside the mixing tank and is used to detect the temperature of the liquid in the mixing tank. The heater is located on the side wall of the mixing tank and is used to heat the liquid in the mixing tank.

6. The glycated hemoglobin detection device according to claim 5, characterized in that, The glycated hemoglobin detection device also includes a waste liquid tank, which is connected to the tester via a waste liquid collection valve.

7. The glycated hemoglobin detection device according to claim 6, characterized in that, A sample pool is provided at the bottom of the injection needle.

8. The glycated hemoglobin detection device according to claim 7, characterized in that, An injection pump is provided between the injection needle and the injection valve.

9. The glycated hemoglobin detection device according to claim 8, characterized in that, The tester is connected to a display device, which is used to display the test results.

Images