Low-temperature transportation incubator for cell samples
By designing a double-layer insulation structure and sealing mechanism, the problem of temperature instability during stem cell transportation was solved, ensuring the low-temperature storage and temperature stability of cell samples during transportation and protecting cell viability.
Patent Information
- Application Number
- CN202423297797.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-31
- Publication Date
- 2025-11-18
- Estimated Expiration
- 2034-12-31
AI Technical Summary
In existing technologies, a constant low-temperature environment cannot be maintained during stem cell transportation, leading to temperature fluctuations that may cause cell death or loss of activity.
A cell sample cryogenic transport insulated box comprising an insulated outer box and an insulated inner box was designed. The bottom of the inner box has an insulation pad, and the inner box and the outer box are connected by a sliding groove and a spring. It is equipped with a placement box, a heat exhaust hole, a diffusion frame, and a placement rack to enhance the cryogenic storage effect. The sealing and stability are improved by sealing rings and self-locking casters.
This technology enables low-temperature storage of cell samples, reduces the impact of external environmental temperature on cells, ensures temperature stability and airtightness during transportation, improves insulation effect, and protects cell viability.
Smart Images

Figure CN223560284U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of insulated boxes, specifically an insulated box for the low-temperature transport of cell samples. Background Technology
[0002] Stem cell research and clinical application is a systematic undertaking requiring coordination among multiple disciplines, institutions, and departments. Currently, stem cell culture technology is becoming increasingly mature, and stem cell applications are being widely implemented. Stem cell clinical research and treatment require independent cell preparation units to provide cells, and to ensure these cells reach optimal viability for both research and clinical application, standardized cell storage and transportation procedures are necessary. Currently, due to the influence of stem cell bioactivity, stem cells cannot maintain optimal cell viability for extended periods, nor can they be guaranteed to be stored at a suitable temperature for long periods. Furthermore, some medical devices need to be carried during stem cell transportation.
[0003] A cell cryogenic transport box, such as one disclosed in announcement number CN210671850U, includes an insulated box comprising a body and a lid. The body contains a cell product placement slot, and the lid is sealed onto this slot. A rubber pad matching the size of the slot bottom is laid on the bottom of the slot. Circular placement slots are distributed at one end of the rubber pad, while elongated placement slots are distributed at the remaining positions. A partition is provided between the circular and elongated placement slots, and the partition is snapped onto the inner wall of the placement slot. By embedding and fixing tube-packaged and bagged cell products respectively in the circular and elongated placement slots, and separating them with the partition, the fixed tube-packaged and bagged cell products are prevented from shaking and colliding. The rubber pad provides good cushioning, offering good fixation and protection. The partition is detachable and can be installed inside the box, allowing for efficient use of the internal space.
[0004] However, based on the working principle proposed in the aforementioned patent, the applicant believes that the device, which relies solely on the closure of the box to keep the cell samples warm during cell sample transportation, may not be able to maintain a constant low temperature inside the box. This could lead to significant temperature differences inside the box during transportation, which could result in cell death, damage, or loss of activity.
[0005] Therefore, a cell sample cryogenic transport insulated box is proposed to address the above problems. Utility Model Content
[0006] To address the shortcomings of existing technologies, particularly the lack of a low-temperature insulation mechanism, this invention provides a cell sample low-temperature transport insulation box.
[0007] The technical solution adopted by this utility model to solve its technical problem is: a cell sample low-temperature transport insulated box, including an insulated outer box; an insulated inner box is movably installed inside the insulated outer box, an insulated pad is fixedly installed on the inner wall of the bottom of the insulated inner box, a sliding groove is opened on the bottom of one side of the insulated inner box, a placement box is movably installed inside the sliding groove, a temperature venting hole is opened on the top of the placement box, a diffusion frame is fixedly installed on the top of the temperature venting hole, and a placement rack is fixedly installed on the top of the inner cavity of the insulated inner box.
[0008] Preferably, the top of the placement rack has several placement holes on one side, and the top of the placement rack has a slot. An isolation plate is movably installed inside the slot, and a T-shaped block is fixedly installed at the bottom of the isolation plate.
[0009] Preferably, a first sealing ring is fixedly installed on the top of the insulated inner box, and positioning seats are fixedly installed on the top of both sides of the insulated inner box. A limit rod is fixedly installed inside the positioning seat, and a box cover is sleeved on the surface of the limit rod.
[0010] Preferably, a shock-absorbing pad is fixedly installed on the inner wall of the bottom of the insulated outer box, and several sleeves are fixedly installed on the inner walls around the insulated outer box, with springs movably installed inside the sleeves.
[0011] Preferably, the inner walls of the insulated outer box are movably fitted with abutments, and several T-shaped rods are fixedly installed on the back of the abutments. The T-shaped rods are embedded in the sleeves and located outside the springs.
[0012] Preferably, a second sealing ring is fixedly installed on the top of the insulated outer box, and an end cap is movably installed on the top of the insulated outer box.
[0013] Preferably, handles are fixedly installed on the top of both the left and right sides of the insulated outer box, and self-locking casters are fixedly installed at the four corners of the bottom of the insulated outer box.
[0014] The beneficial effects of this utility model are:
[0015] 1. This utility model achieves the function of low-temperature storage of cell samples through the structural design of an insulated outer box, an insulated inner box, an insulated pad, a placement box, a heat exhaust hole, a diffusion frame, and a placement rack, and through the cooperation between the structures. Thus, by storing a low-temperature cooling medium, a cooling gas can be provided to the cell sample storage space in real time, thereby reducing the impact of external environmental temperature on the cell samples. At the same time, the double insulated box further improves the insulation effect of low-temperature transportation and solves the problem of lacking a low-temperature insulation mechanism.
[0016] 2. This utility model, through the setting of the first sealing ring, facilitates the increase of the sealing performance of the contact surface between the box cover and the insulated inner box, thereby effectively preventing the cold air from leaking out of the insulated inner box, thus ensuring the long-term stability of the internal temperature of the insulated inner box and achieving the purpose of improving the insulation effect. Attached Figure Description
[0017] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0018] Figure 1 This is a frontal perspective three-dimensional schematic diagram of the overall structure of this utility model;
[0019] Figure 2 This is a partial cross-sectional view of the thermal insulation outer box structure of this utility model;
[0020] Figure 3 This is a schematic diagram of the interior of the thermal insulation inward structure of this utility model;
[0021] Figure 4 This is an enlarged schematic diagram of a partial structure of the present invention;
[0022] Figure 5 This is a schematic cross-sectional view of the insulated inner box structure of this utility model.
[0023] In the diagram: 1. Insulated outer box; 2. Insulated inner box; 3. Insulation pad; 4. Slide groove; 5. Placement box; 6. Exhaust vent; 7. Diffuser frame; 8. Placement rack; 9. Placement hole; 10. Slot; 11. Isolation plate; 12. T-shaped block; 13. First sealing ring; 14. Positioning seat; 15. Limiting rod; 16. Box cover; 17. Shock-absorbing pad; 18. Sleeve; 19. Spring; 20. Support plate; 21. T-shaped rod; 22. Second sealing ring; 23. End cap; 24. Handle; 25. Self-locking caster wheel. Detailed Implementation
[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.
[0025] The following is in conjunction with the appendix Figure 1-5 This application will be described in further detail.
[0026] This application discloses a cell sample low-temperature transport insulated box, including an insulated outer box 1; an insulated inner box 2 is movably installed inside the insulated outer box 1, an insulated pad 3 is fixedly installed on the inner wall of the bottom of the insulated inner box 2, a sliding groove 4 is opened on the bottom of one side of the insulated inner box 2, a placement box 5 is movably installed inside the sliding groove 4, a heat exhaust hole 6 is opened on the top of the placement box 5, a diffusion frame 7 is fixedly installed on the top of the heat exhaust hole 6, and a placement rack 8 is fixedly installed on the top of the inner cavity of the insulated inner box 2.
[0027] Reference Figure 1 , Figure 3 , Figure 4 , Figure 5 By combining the outer insulated box 1, the inner insulated box 2, the insulation pad 3, the placement box 5, the exhaust hole 6, the diffusion frame 7, and the placement rack 8, the function of low-temperature storage of cell samples is realized. Thus, by storing low-temperature cooling media, cooling gas can be provided to the cell sample storage space in real time, thereby reducing the impact of external environmental temperature on cell samples. At the same time, the double insulated box further improves the insulation effect of low-temperature transportation.
[0028] The top of the placement rack 8 has several placement holes 9 on one side, and a slot 10 is provided on the top of the placement rack 8. An isolation plate 11 is movably installed inside the slot 10, and a T-shaped block 12 is fixedly installed at the bottom of the isolation plate 11.
[0029] Reference Figure 4 and Figure 5 The placement hole 9 and the isolation plate 11 facilitate the positioning of different cell sample storage containers, thereby increasing the applicability of the incubator. The slot 10 and the T-shaped block 12 facilitate the positioning of the isolation plate 11, thereby ensuring the stability of the isolation plate 11 during movement.
[0030] A first sealing ring 13 is fixedly installed on the top of the insulated inner box 2. Positioning seats 14 are fixedly installed on the top of both sides of the insulated inner box 2. Limiting rods 15 are fixedly installed inside the positioning seats 14. A box cover 16 is sleeved on the surface of the limiting rods 15.
[0031] Reference Figure 1 and Figure 5 The first sealing ring 13 facilitates the sealing of the contact surface between the lid 16 and the inner insulated box 2, thereby effectively preventing the cold air from leaking out of the inner insulated box 2, thus ensuring the long-term stability of the internal temperature of the inner insulated box 2 and achieving the purpose of improving the insulation effect. The lid 16 facilitates the closure of the top opening of the inner insulated box, preventing foreign objects from entering the inner insulated box 2.
[0032] A shock-absorbing pad 17 is fixedly installed on the inner wall of the bottom of the insulated outer box 1. Several sleeves 18 are fixedly installed on the inner walls of the four sides of the insulated outer box 1. Springs 19 are movably installed inside the sleeves 18.
[0033] Reference Figure 2 The shock-absorbing pad 17 facilitates contact with the bottom surface of the inner insulated box 2, reducing the impact on the inner insulated box 2 during transportation, thereby ensuring the stability of cell samples during transportation. It can also effectively reduce wear on the inner insulated box 2 and the outer insulated box 1. The spring 19 utilizes its deformable properties to make the outer insulated box 1 adaptable to different sizes of inner insulated boxes 2. At the same time, it can work with the T-shaped rod 21 to buffer and stabilize external impacts, reducing the impact of vibration on the inner insulated box 2 and the samples.
[0034] All four inner walls of the insulated outer box 1 are movably fitted with a backing plate 20. Several T-shaped rods 21 are fixedly installed on the back of the backing plate 20. The T-shaped rods 21 are embedded in the sleeve 18 and located outside the spring 19.
[0035] Reference Figure 2 The abutment plate 20 facilitates the increase of the contact area between the T-shaped rod 21 and the insulated inner box 2, thereby achieving the purpose of fully clamping the insulated inner box 2.
[0036] A second sealing ring 22 is fixedly installed on the top of the insulated outer box 1, and an end cap 23 is movably installed on the top of the insulated outer box 1.
[0037] Reference Figure 1 and Figure 2 The second sealing ring 22 facilitates the sealing of the connection between the insulated outer box 1 and the end cap 23, and can also effectively prevent gas leakage in the insulated outer box 1, thereby ensuring the stability of the temperature of the air gap in the insulated outer box 1. The end cap 23 facilitates the closure of the opening at the top of the insulated outer box 1, further enhancing the insulation of the cell samples.
[0038] Handles 24 are fixedly installed on the top of both sides of the insulated outer box 1, and self-locking casters 25 are fixedly installed at the four corners of the bottom of the insulated outer box 1.
[0039] Reference Figure 1 and Figure 2 The handle 24 facilitates operation during transport of the entire device, while the self-locking casters 25 facilitate the movement of the insulated outer box 1. The self-locking function ensures that the box remains fixed, increasing the practicality of the entire device.
[0040] Working principle: When using this device, place the cell sample container on the corresponding placement hole 9 or both sides of the isolation plate 11. The placement box 5 carries the cooling medium. After the placement box 5 is inserted into the insulated inner box 2 through the sliding groove 4, the box cover 16 is rotated to close the top opening of the insulated inner box 2. At the same time, the first sealing ring 13 is pressed, which increases the overall sealing of the insulated inner box 2. The insulated inner box 2 is placed in the insulated outer box 1. The tension of the spring 19 pushes the T-shaped rod 21. The T-shaped rod 21 drives the abutment plate 20 to clamp the insulated inner box 2. The end cover 23 is installed. The end cover 23 presses the second sealing ring 22, which increases the sealing of the insulated outer box 1. During transportation, the entire insulated box exchanges heat with the gas in the insulated inner box 2 through the contact between the cooling medium inside the placement box 5 and the gas. The cooling medium is evenly dispersed into the inner cavity of the insulated inner box 2 through the diffusion frame 7, providing a low-temperature storage environment for the cell samples in real time.
[0041] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.
Claims
1. A cell sample cryogenic transport insulated box, characterized in that: The device includes an insulated outer box (1); an insulated inner box (2) is movably installed inside the insulated outer box (1); an insulated pad (3) is fixedly installed on the inner wall of the bottom of the insulated inner box (2); a sliding groove (4) is opened on the bottom of one side of the insulated inner box (2); a placement box (5) is movably installed inside the sliding groove (4); a heat exhaust hole (6) is opened on the top of the placement box (5); a diffuser frame (7) is fixedly installed on the top of the heat exhaust hole (6); and a placement rack (8) is fixedly installed on the top of the inner cavity of the insulated inner box (2).
2. The cell sample low-temperature transport insulated box according to claim 1, characterized in that: The placement rack (8) has several placement holes (9) on one side of its top, and a slot (10) is provided on the top of the placement rack (8). An isolation plate (11) is movably installed inside the slot (10), and a T-shaped block (12) is fixedly installed at the bottom of the isolation plate (11).
3. The cell sample low-temperature transport insulated box according to claim 1, characterized in that: The top of the insulated inner box (2) is fixedly installed with a first sealing ring (13), and the tops of both sides of the insulated inner box (2) are fixedly installed with positioning seats (14). The inside of the positioning seats (14) is fixedly installed with a limit rod (15), and the surface of the limit rod (15) is covered with a box cover (16).
4. The cell sample low-temperature transport insulated box according to claim 1, characterized in that: The inner wall of the bottom of the heat-insulating outer box (1) is fixedly installed with a shock-absorbing pad (17), and several sleeves (18) are fixedly installed on the inner walls around the heat-insulating outer box (1). Springs (19) are movably installed inside the sleeves (18).
5. A cell sample low-temperature transport insulated box according to claim 1, characterized in that: The inner walls of the insulated outer box (1) are movably fitted with abutment plates (20). Several T-shaped rods (21) are fixedly installed on the back of the abutment plates (20). The T-shaped rods (21) are embedded in the sleeve (18) and located outside the spring (19).
6. The cell sample low-temperature transport insulated box according to claim 1, characterized in that: The top of the insulated outer box (1) is fixedly installed with a second sealing ring (22), and the top of the insulated outer box (1) is movably installed with an end cap (23).
7. The cell sample low-temperature transport insulated box according to claim 1, characterized in that: Handles (24) are fixedly installed on the top of both sides of the insulated outer box (1), and self-locking casters (25) are fixedly installed at the four corners of the bottom of the insulated outer box (1).
Citation Information
Patent Citations
Low-temperature cell transport case
CN210671850U