Rapid gel preparation device applied to immunoelectrophoresis gel

Abstract

The utility model provides a rapid gel preparation device, belongs to the technical field of immunoelectrophoresis gel, and particularly relates to a rapid gel preparation device applied to immunoelectrophoresis gel, which comprises symmetrically distributed gel combs, the upper parts of the gel combs are connected with sealing covers through connecting blocks, and the sealing covers correspond to the gel combs and are arranged above the gel combs; an adjusting block is arranged on the inner side of the lower portion of the glue comb, an adjusting gear is arranged in the adjusting block, a reset tension spring is connected to the lower portion of the adjusting block through a T-shaped limiting piece, the glue comb, the sealing cover and the adjusting block are arranged to form a slidable three-section type connecting box body, and the adjusting block is driven to slide by sliding the glue comb through the adjusting gear; when the reset tension spring is larger than the thrust of the gel comb part on the adjusting gear, the adjusting gear rotates, meanwhile, the adjusting block resets and slides next time, gel is flatly filled between gel combs through the repeated movement of the adjusting block, and follow-up operation is facilitated.

Description

Technical Field

[0001] This invention provides a rapid gel preparation device, belonging to the field of immunoelectrophoresis gel technology, and particularly relates to a rapid gel preparation device for immunoelectrophoresis gels. Background Technology

[0002] Electrophoresis is a separation technique that uses an electric field to drive the migration of charged particles in a medium. In biology, chemistry, and medicine, electrophoresis is commonly used to separate, identify, and analyze proteins, nucleic acids, polysaccharides, and other charged biomolecules. Electrophoresis is based on the fact that different molecules migrate at different speeds in an electric field, thus achieving the separation of various components in a sample.

[0003] Current immunoelectrophoresis procedures involve precisely injecting immunoelectrophoresis gels into various reservoirs. This step requires technicians to manually add and fill the reservoirs one by one using syringes, followed by sealing with a gel comb. This process is not only cumbersome but also makes it difficult to ensure the uniformity of gel injection. Furthermore, air bubbles can easily form during the placement of the gel comb, affecting the accuracy and reproducibility of the experimental results. Utility Model Content

[0004] In order to overcome the shortcomings of the prior art, this application provides a rapid gel preparation device for immunoelectrophoresis gels, which solves the problem that the operation of existing gel preparation devices for electrophoresis experiments is too cumbersome and inconvenient.

[0005] To solve the above-mentioned technical problems, the present invention provides the following technical solution: a rapid gel mixing device for immunoelectrophoresis gels, comprising symmetrically distributed gel combs, a cap corresponding to itself and placed above the gel combs is connected to the top of the gel combs via a connecting block, an adjusting block is provided on the inner side of the bottom of the gel combs, an adjusting gear is provided inside the adjusting block, and a reset spring is connected to the bottom of the adjusting block via a T-shaped limiting member.

[0006] Preferably, the limiting member is fitted with a shell corresponding to itself and penetrated by a rubber comb, and the reset spring is fixedly connected to the shell.

[0007] Preferably, the shell has sealing grooves on both sides corresponding to the rubber comb, the rubber comb is in close contact with the sealing groove, and a connecting plate is fixedly connected to the side of the rubber comb near the cover. The connecting plate has several evenly distributed through holes that penetrate through itself, and the through holes and the rubber comb are distributed alternately.

[0008] Preferably, the through hole has T-shaped limiting grooves on both sides corresponding to the connecting block, and the cover and the connecting plate are slidably connected by the limiting grooves.

[0009] Preferably, the adjusting block is provided with uniformly distributed grooves on two sides close to the sealing groove, the two sides of the adjusting gear are fixedly connected with reset torsional springs arranged in the adjusting block, the adjusting gear is movably connected with the adjusting block through the penetrating shaft of the adjusting gear, and the side close to the adjusting gear of the connecting plate is provided with a plurality of uniformly distributed protrusions corresponding to the adjusting gear.

[0010] The one or more technical solutions provided in the embodiments of the application have at least the following technical effects or advantages:

[0011] The utility model discloses a three-section type connecting box body formed by setting up the glue comb, the cover and the adjusting block can slide, and the glue comb is slid by the adjusting gear to drive the adjusting block to slide, when the reset tension spring is greater than the pushing force of the glue comb part to the adjusting gear, the adjusting gear rotates, the adjusting block resets at the same time, and the next sliding is carried out, through the repeated movement of the adjusting block, the gel is filled flat between the glue combs, and subsequent operation is facilitated.

[0012] Other advantages, objects and features of the utility model will be described in the subsequent specification to some extent, and to some extent, it will be obvious to those skilled in the art based on the study of the following text or can be taught from the practice of the utility model. BRIEF DESCRIPTION OF DRAWINGS

[0013] Figure 1 It is a three-dimensional schematic view of the utility model of a kind of fast glue preparation device for immunoelectrophoresis gel;

[0014] Figure 2 It is the opening state schematic view of the utility model of a kind of fast glue preparation device for immunoelectrophoresis gel;

[0015] Figure 3 It is the sectional view of the connecting plate of the utility model of a kind of fast glue preparation device for immunoelectrophoresis gel;

[0016] Figure 4 It is the sectional view of the adjusting block of the utility model of a kind of fast glue preparation device for immunoelectrophoresis gel;

[0017] Figure 5 It is the sectional view of the shell of the utility model of a kind of fast glue preparation device for immunoelectrophoresis gel.

[0018] As shown in the figure:

[0019] 1, glue comb;

[0020] 11, connecting block;12, cover;13, connecting plate;14, through hole;15, limit groove;16, protrusion;

[0021] 2, adjusting block;

[0022] 21, adjusting gear; 22, limiting piece; 23, reset tension spring; 24, shell; 25, sealing groove; 26, groove; 27, reset torsion spring. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.

[0024] It should be noted that the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are for illustrative purposes only and do not represent the only implementation.

[0025] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present application belongs; the terms used in the specification of the present application are only for the purpose of describing specific embodiments and are not intended to limit the present application; the term "and / or" used herein includes any and all combinations of one or more related listed items.

[0026] As shown in Figure 1 and Figure 3 A rapid gel preparation device applied to immunoelectrophoresis gel, comprising symmetrically distributed gel combs 1, a cover 12 corresponding to and above the gel combs 1 is connected to the upper part of the gel combs 1 through a connecting block 11, an adjusting block 2 is arranged on the inner side of the lower part of the gel combs 1, an adjusting gear 21 is arranged in the adjusting block 2, evenly distributed grooves 26 are arranged on both sides of the adjusting block 2 close to a sealing groove 25, reset torsion springs 27 are fixedly connected to both sides of the adjusting gear 21 and arranged in the adjusting block 2, the adjusting gear 21 is movably connected to the adjusting block 2 through a rotating shaft penetrating through the adjusting gear 21, a plurality of protrusions 16 corresponding to and meshing with the adjusting gear 21 are arranged on one side of a connecting plate 13 close to the adjusting gear 21, and a reset tension spring 23 is connected to the lower part of the adjusting block 2 through a T-shaped limiting piece 22.

[0027] In the embodiment, the three-section connecting box body is slidably formed by the gel combs 1, the cover 12 and the adjusting block 2, the gel combs 1 are slid to drive the adjusting block 2 through the adjusting gear 21, when the elastic force generated by the reset tension spring 23 is greater than the thrust of the gel combs 1 on the adjusting gear 21, the adjusting gear 21 rotates, the adjusting block 2 resets and moves again, and the gel is filled between the gel combs 1 through the repeated movement of the adjusting block 2, thereby facilitating subsequent operation.

[0028] As Figure 2 , 4 , 5 shown, the external set of limiting member 22 with and its corresponding and the glue comb 1 through the shell 24, reset tension spring 23 and shell 24 fixed connection, both sides of the shell 24 is provided with and the glue comb 1 corresponding sealing groove 25, the glue comb 1 close to the sealing groove 25, the glue comb 1 near the side of the cover 12 is fixedly connected with the connecting plate 13, the connecting plate 13 is provided with a plurality of evenly distributed and through its own through hole 14, the through hole 14 and the glue comb 1 alternate distribution, both sides of the through hole 14 is provided with and the connecting block 11 corresponding T type limit slot 15, the cover 12 and the connecting plate 13 by means of limit slot 15 to realize the sliding connection.

[0029] In this embodiment, the device is completely opened, as Figure 2 shown, at this time directly add the gel into the shell 24, relative needle tube is more convenient, sliding connecting plate 13, drive the glue comb 1 into the sealing groove 25, the glue comb 1 is transversely sliding into the sealing groove 25, will not extrude air into the inside, reduce the possibility of bubble generation, at the same time in the process of connecting plate 13 sliding, the convex 16 embedded in the gear teeth of the adjusting gear 21, the adjusting gear 21 will not rotate under the action of the reset torsional spring 27, at this time the connecting plate 13 will drive the adjusting block 2 to slide in the shell 24, until the tension of the reset tension spring 23 is enough to twist the reset torsional spring 27, at this time the adjusting gear 21 rotates, the convex 16 leaves the adjusting gear 21, the adjusting block 2 resets and contacts the next convex 16, realizing repeated motion; the adjusting block 2 in the process of repeated motion, by means of the groove 26 on both sides of itself, the gel inside the shell 24 is discharged to both sides of itself, and enters between the glue combs 1, finally drips into the protein sample through the through hole 14, and slides the cover 12 to realize the complete closure of the device.

[0030] In use, first open the device to Figure 2 the state shown, directly add the immune electrophoresis gel into the shell 24, then slowly slide the connecting plate 13, so that the glue comb 1 slides transversely into the sealing groove 25, to reduce the generation of bubbles, the convex 16 on the connecting plate 13 is embedded in the gear teeth of the adjusting gear 21, the adjusting gear 21 will not rotate under the action of the reset torsional spring 27, then the connecting plate 13 drives the adjusting block 2 to slide in the shell 24, until the tension of the reset tension spring 23 is enough to twist the reset torsional spring 27, the adjusting gear 21 rotates, the convex 16 leaves the adjusting gear 21, the adjusting block 2 resets and contacts the next convex 16, realizing repeated motion, the adjusting block 2 by means of the groove 26 on both sides of itself, the gel is discharged to both sides of itself, and enters between the glue combs 1, then drips into the protein sample through the through hole 14 on the connecting plate 13, finally slides the cover 12 to realize the complete closure of the device, places the device on the electrophoresis equipment to carry out the immune electrophoresis experiment, opens the cover 12 after the experiment is finished, takes out the gel to observe and analyze the results.

[0031] Although the utility model has disclosed as above with preferable embodiments, it is not used to limit the utility model, anyone familiar with this technology can make various changes and modifications without departing from the spirit and scope of the utility model, therefore the protection scope of the utility model should be limited by the claims.

Claims

1. A rapid gel casting device for immunoelectrophoresis gels comprising symmetrically distributed gel combs (1), characterized in that: The upper side of the glue comb (1) is connected with a cover (12) corresponding to itself and placed above itself through a connecting block (11), the lower side of the glue comb (1) is provided with an adjusting block (2), the inside of the adjusting block (2) is provided with an adjusting gear (21), the lower side of the adjusting block (2) is connected with a reset tension spring (23) through a T-shaped limiting piece (22).

2. A rapid gel casting device for immunoelectrophoresis gels as claimed in claim 1, wherein: The outside of the limiting piece (22) is provided with a shell (24) corresponding to itself and penetrated by the glue comb (1), and the reset tension spring (23) and the shell (24) are fixedly connected.

3. A rapid gel casting device for immunoelectrophoresis gels according to claim 2, characterized in that: Both sides of the shell (24) are provided with sealing grooves (25) corresponding to the glue comb (1), the glue comb (1) is tightly attached to the sealing grooves (25), one side of the glue comb (1) close to the cover (12) is fixedly connected with a connecting plate (13), a plurality of through holes (14) uniformly distributed and penetrating through the connecting plate (13) are arranged on the connecting plate (13), and the through holes (14) and the glue comb (1) are alternately distributed.

4. A rapid gel casting device for immunoelectrophoresis gels according to claim 3, characterized in that: Both sides of the through hole (14) are provided with T-shaped limiting grooves (15) corresponding to the connecting block (11), and the cover (12) and the connecting plate (13) are slidably connected through the limiting grooves (15).

5. A rapid gel casting device for immunoelectrophoresis gels as claimed in claim 3, wherein: The two sides of the adjusting block (2) close to the sealing grooves (25) are provided with uniformly distributed grooves (26), the two sides of the adjusting gear (21) are fixedly connected with reset torsion springs (27) placed in the inside of the adjusting block (2), the rotating shaft penetrating through the adjusting gear (21) and the adjusting block (2) are movably connected, and a plurality of protrusions (16) uniformly distributed and corresponding to the adjusting gear (21) are arranged on one side of the connecting plate (13) close to the adjusting gear (21).

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