Pipetting assembly and pretreatment device

Abstract

The utility model provides a pipetting assembly and a pretreatment device. And the pipetting assembly comprises a pipetting piece, a storage rack and an anti-error insertion piece. The pipetting piece comprises a first pipetting piece and a second pipetting piece, and the size parameter of the first pipetting piece is different from the size parameter of the second pipetting piece. The storage rack is provided with a first storage position and a second storage position. The anti-error insertion piece is arranged corresponding to the first storage position, the first pipetting piece is arranged at the first storage position through the anti-error insertion piece, the second pipetting piece is arranged at the second storage position, and the anti-error insertion piece is used for preventing the second pipetting piece from being inserted into the first storage position. The first pipetting piece and the second pipetting piece have different boundary dimensions, a first storage position and a second storage position which respectively correspond to the first pipetting piece and the second pipetting piece are arranged in the storage rack, and the anti-error insertion piece can be arranged in the first storage position and has a blocking effect, so that the second pipetting piece is prevented from being wrongly inserted into the first storage position; the situation of manual misoperation is effectively avoided, and then the efficiency and accuracy of biological detection are improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of sample processing, in particular to a pipette assembly and a pretreatment device. BACKGROUND

[0002] Targeted next generation sequencing (tNGS) sample pretreatment automation equipment has important applications in biomedical and life science research fields, and promotes the wide application and development of targeted next generation sequencing technology. The tNGS sample pretreatment automation equipment is composed of a front cup processing module, a high-speed centrifugation module and a rear cup processing module. Among them, the front cup processing module mainly transfers biological samples to centrifugal tubes and adds internal reference bacteria liquid. The high-speed centrifugation module mainly separates the biological samples into different levels or precipitates, which is convenient for subsequent analysis and processing. The rear cup processing module mainly resuspends and mixes the biological samples after high-speed centrifugation or transfers them.

[0003] During the processing of the front cup processing module, the biological sample is transferred from the sample tube to the centrifugal tube by using the sampling tube. Sampling tubes of different lengths are placed in different positions of the tube rack to meet different use scenarios. When the operator places the sampling tube in the tube rack by manual method, the sampling tube is often placed in the wrong position, which causes the tNGS sample pretreatment automation equipment to be unable to use the correct sampling tube, and further causes the failure rate of the equipment to be high, which greatly affects the efficiency and results of biological detection. UTILITY MODEL CONTENTS

[0004] In order to at least partially solve the problems existing in the prior art, according to one aspect of the utility model, a pipette assembly is provided. The pipette assembly comprises a pipette, a storage rack and a mistaken insertion prevention component. The pipette comprises a first pipette and a second pipette, and the size parameters of the first pipette and the second pipette are different. The storage rack is provided with a first storage position and a second storage position. The mistaken insertion prevention component is arranged corresponding to the first storage position, the first pipette is arranged in the first storage position through the mistaken insertion prevention component, the second pipette is arranged in the second storage position, and the mistaken insertion prevention component is used to block the second pipette from being inserted into the first storage position.

[0005] The pipette assembly of the utility model has different outer dimensions of the first pipette and the second pipette, the storage rack is provided with the first storage position and the second storage position corresponding to the first pipette and the second pipette respectively, the mistaken insertion prevention component can be arranged in the first storage position and play a blocking role, so as to avoid the second pipette from being mistakenly inserted into the first storage position, which effectively avoids the manual misoperation, and further improves the efficiency and accuracy of biological detection.

[0006] Exemplarily, the storage rack has an inner side wall at the first storage position, the mistaken insertion prevention component is arranged on the inner side wall, and is arranged close to the upper surface of the storage rack.

[0007] Exemplarily, the storage rack is configured as a frame structure, and the anti-misplug component is configured as a plate, a plate surface of the anti-misplug component is perpendicular to the inner side wall, and is arranged in parallel with the upper surface of the storage rack.

[0008] Exemplarily, the anti-misplug component comprises a fixed part and a through hole penetrating through the fixed part, a center line of the through hole is parallel to the inner side wall, and the first pipette is arranged in the through hole.

[0009] Exemplarily, a preset interval is arranged between the upper surface of the storage rack and the upper surface of the fixed part, and the preset interval is smaller than an interval from the bottom of the second pipette to the upper surface of the fixed part.

[0010] Exemplarily, the through hole and the second pipette are both circular in cross section, and a diameter of the through hole is smaller than a diameter of the second pipette.

[0011] Exemplarily, the frame structure comprises an upper cover body and a side cover body, the upper cover body is movably connected to the side cover body through a clamping structure.

[0012] According to another aspect of the present application, a pre-treatment device is also provided, comprising a mounting platform, a feeding assembly, an opening and closing assembly and a pipetting assembly as described above, the mounting platform has a first region, a second region and a third region arranged independently, the feeding assembly is arranged on the first region, the pipetting assembly is arranged on the second region, and the opening and closing assembly is arranged on the third region.

[0013] Exemplarily, the mounting platform comprises a placement table and a body arranged below the placement table, the feeding assembly, the opening and closing assembly and the pipetting assembly are all arranged on the placement table, and the placement table is movably connected to the body.

[0014] Exemplarily, the first region is provided with a positioning column, the feeding assembly is provided with a groove matched with the positioning column, and the positioning column is arranged in the groove.

[0015] The above description is only a summary of the technical scheme of the present application, in order to more clearly understand the technical means of the present application, the specific embodiments of the present application can be implemented according to the content of the specification, and in order to make the above and other purposes, characteristics and advantages of the present application more obvious, the following specific embodiments of the present application are described. BRIEF DESCRIPTION OF DRAWINGS

[0016] The above and other purposes, characteristics and advantages of the present application will become more apparent through a more detailed description of the embodiments of the present application combined with the accompanying drawings. The accompanying drawings are used to provide a further understanding of the embodiments of the present application, and constitute a part of the specification, and are used to explain the present application together with the embodiments of the present application, and do not constitute a limitation on the present application. In the drawings, the same reference numerals generally represent the same components or steps.

[0017] Figure 1 A perspective view of a pipetting assembly according to an example embodiment of the present application is shown.

[0018] Figure 2 A perspective view of a pre-treatment device according to an example embodiment of the present application is shown.

[0019] In the drawings, reference numerals indicate the components in the following list:

[0020] 1, pipette; 11, first pipette; 12, second pipette; 2, storage rack; 21, upper cover body; 22, side cover body; 3, anti-misplug component; 4, clamping structure; 5, feeding assembly; 6, switch cover assembly; 7, first area; 8, second area; 9, third area; 10, placement table. DETAILED DESCRIPTION

[0021] In order to make the purpose, technical scheme and advantages of the present application more obvious, the example embodiments according to the present application will be described in detail below with reference to the drawings. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application, and it should be understood that the present application is not limited by the example embodiments described herein. Based on the embodiments of the present application described in the present application, all other embodiments obtained by those skilled in the art without creative labor should fall within the scope of protection of the present application.

[0022] In the following description, a large number of details are provided in order to enable a thorough understanding of the present application. However, those skilled in the art can understand that the description below only exemplarily shows the preferred embodiments of the present application, and the present application can be implemented without one or more such details. In addition, in order to avoid confusion with the present application, some technical features known in the art are not described in detail.

[0023] In order to thoroughly understand the embodiments of the present application, detailed structures will be proposed in the following description. Obviously, the implementation of the embodiments of the present application is not limited to the special details familiar to those skilled in the art. The preferred embodiments of the present application are described in detail as follows, however, in addition to these detailed descriptions, the present application can have other embodiments.

[0024] An embodiment of the present application provides a pipetting assembly, which can effectively avoid the occurrence of manual misoperation. Hereinafter, a pipetting assembly according to an embodiment of the present application will be introduced in detail with reference to the drawings.

[0025] As Figure 1As shown, the pipetting assembly includes a pipetting component 1, a storage rack 2 and a mistaken insertion prevention component 3. The pipetting component 1 includes a first pipetting component 11 and a second pipetting component 12, the first pipetting component 11 and the second pipetting component 12 have different size parameters. The storage rack 2 is provided with a first storage position and a second storage position. The mistaken insertion prevention component 3 is arranged corresponding to the first storage position, the first pipetting component 11 is arranged in the first storage position through the mistaken insertion prevention component 3, the second pipetting component 12 is arranged in the second storage position, and the mistaken insertion prevention component 3 is used for preventing the second pipetting component 12 from being inserted into the first storage position.

[0026] The storage rack 2 can have a plurality of first storage positions and a plurality of second storage positions, the first storage positions can be used for storing the first pipetting component 11, and the second storage positions can be used for storing the second pipetting component 12.

[0027] The first pipetting component 11 can have a shorter length than the second pipetting component 12, during the process of inserting the second pipetting component 12 into the first storage position, the second pipetting component 12 can abut against the mistaken insertion prevention component 3, so as to limit the second pipetting component 12 from continuing to be inserted into the first storage position. And the first pipetting component 11 can avoid abutting against the mistaken insertion prevention component 3 when being inserted into the first storage position, so as to be smoothly inserted into the first storage position.

[0028] The pipetting assembly of the utility model, the first pipetting component 11 and the second pipetting component 12 have different external dimensions, the storage rack 2 is provided with the first storage position and the second storage position corresponding to the first pipetting component 11 and the second pipetting component 12 respectively, the mistaken insertion prevention component 3 can be arranged in the first storage position and play a blocking role, so as to avoid the second pipetting component 12 from being inserted into the first storage position by mistake, so that the manual misoperation is effectively avoided, and the efficiency and accuracy of biological detection are improved.

[0029] In some embodiments, as Figure 1 As shown, the storage rack 2 has an inner side wall at the first storage position, and the mistaken insertion prevention component 3 is arranged on the inner side wall and close to the upper surface of the storage rack 2.

[0030] The mistaken insertion prevention component 3 and the inner side wall can be detachably connected or integrally formed, and the detachable connection can include plug-in connection or adhesive connection, which is not limited in the application.

[0031] The mistaken insertion prevention component 3 can be arranged close to the upper surface of the storage rack 2, that is, the distance between the mistaken insertion prevention component 3 and the upper surface of the storage rack 2 can be matched with the length of the first pipetting component 11, so that the first pipetting component 11 can be stably and smoothly inserted into the first storage position.

[0032] In the above embodiment, the mistaken insertion prevention component 3 is arranged close to the upper surface of the storage rack 2, which can play a better blocking effect, and further effectively prevent the second pipetting component 12 from being incorrectly inserted into the first storage position, thereby effectively improving the mistaken insertion prevention effect of the mistaken insertion prevention component 3.

[0033] In some embodiments, as shown in Figure 1 The storage rack 2 is configured as a frame structure, and the anti-misplug component 3 is configured as a plate. The plate surface of the anti-misplug component 3 is perpendicular to the inner side wall and is arranged in parallel with the upper surface of the storage rack 2.

[0034] The frame structure of the storage rack 2 can have good stability and load-bearing capacity, ensuring the structural stability of the storage rack 2.

[0035] The plate-shaped anti-misplug component 3 can have a side wall surface, which can be connected perpendicularly to the inner side wall surface of the storage rack 2. The plate surface of the anti-misplug component 3 can be parallel to the upper surface of the storage rack 2, thereby greatly facilitating the storage and retrieval of the first pipette 11.

[0036] In the above embodiments, the plate surface of the anti-misplug component 3 can be perpendicular to the inner side wall and parallel to the upper surface of the storage rack 2. In this way, the first pipette 11 located in the first storage position can be smoothly and conveniently retrieved, and the second pipette 12 can also be blocked, effectively improving the layout rationality of the pipetting assembly.

[0037] In some embodiments, as shown in Figure 1 The anti-misplug component 3 includes a fixed portion and a through hole penetrating the fixed portion. The center line of the through hole is parallel to the inner side wall, and the first pipette 11 is arranged in the through hole.

[0038] In the above embodiments, when the first pipette 11 is placed in the first storage position, the first pipette 11 can be arranged in the through hole of the anti-misplug component 3 and abut against the inner side wall of the through hole. Thus, while ensuring that the first pipette 11 can be placed in the first storage position, the displacement and shaking of the first pipette 11 are also limited, effectively ensuring the stability and firmness of the connection between the first pipette 11 and the storage rack 2.

[0039] In some embodiments, as shown in Figure 1 The upper surface of the storage rack 2 and the upper surface of the fixed portion have a predetermined spacing, and the spacing from the bottom of the second pipette 12 to the upper surface of the fixed portion is greater than the predetermined spacing.

[0040] The spacing from the bottom of the second pipette 12 to the upper surface of the fixed portion can be greater than the predetermined spacing, and the spacing from the bottom of the first pipette 11 to the upper surface of the fixed portion can be less than the predetermined spacing. Thus, only the first pipette 11 can meet the requirement of the predetermined spacing, thereby preventing the second pipette 12 from being placed in the first storage position by mistake.

[0041] The preset distance between the storage rack 2 and the fixing part can be accurately controlled according to the length of the pipette 1, so that the space of the storage rack 2 can be more effectively utilized, and different lengths of pipettes 1 can be compatible.

[0042] In the above embodiment, the preset distance can be smaller than the distance from the bottom of the second pipette 12 to the upper surface of the fixing part, so that when the second pipette 12 is inserted into the first storage position, the anti-misinsertion device 3 can be located on the insertion path of the second pipette 12 to block the second pipette 12, further improving the anti-misinsertion effect and reliability of the anti-misinsertion device 3.

[0043] In some embodiments, as shown in Figure 1 The through hole and the second pipette 12 are both circular in cross section, and the diameter of the through hole is smaller than the diameter of the second pipette 12.

[0044] The diameter of the through hole can be smaller than the diameter of the second pipette 12, so that when the second pipette 12 is inserted into the first storage position, the second pipette 12 cannot pass through the through hole and is stably placed in the first storage position.

[0045] The through hole and the second pipette 12 can also be square or elliptical in cross section, and the present application does not make specific limitations on this, as long as the through hole can limit the displacement of the second pipette 12 in the insertion direction.

[0046] In the above embodiment, the diameter of the through hole can be smaller than the diameter of the second pipette 12, and the diameter of the through hole can be larger than the diameter of the first pipette 11, so as to ensure that only the first pipette 11 can be inserted into the through hole, avoiding the second pipette 12 being mistakenly inserted into the through hole, reducing the potential risks caused by misoperation, and effectively improving the reliability and practicality of the pipette assembly.

[0047] In some embodiments, as shown in Figure 1 The frame structure includes an upper cover body 21 and a side cover body 22, and the upper cover body 21 is movably connected to the side cover body 22 by the clamping structure 4.

[0048] The upper cover body 21 can have a plurality of through holes, and the diameters of some of the through holes can be adapted to the diameter of the first pipette 11, and the diameters of the other through holes can be adapted to the diameter of the second pipette 12, so that the first pipette 11 and the second pipette 12 can be placed in the first storage position and the second storage position, respectively, through the corresponding through holes.

[0049] The clamping structure 4 can be arranged on the side cover body 22, the clamping structure 4 can have a certain elastic deformation, and the upper cover body 21 can be limited on the side cover body 22 under the action of the clamping structure 4, and when the clamping structure 4 is pressed in a direction away from the pipette 1, the upper cover body 21 can be detached from the side cover body 22.

[0050] The number of the clamping structure 4 can be two, and the two clamping structures 4 can be arranged on opposite sides of the upper cover body 21, so as to ensure the firmness of the connection between the upper cover body 21 and the side cover body 22.

[0051] In the above embodiment, the upper cover body 21 can be movably connected to the side cover body 22 through the clamping structure 4, so as to ensure the stability of the connection between the upper cover body 21 and the side cover body 22, and avoid the accidental falling. Moreover, the clamping structure 4 allows the upper cover body 21 to be quickly and conveniently connected and separated from the side cover body 22, greatly facilitates the assembly and maintenance of the storage rack 2, and effectively improves the practicability of the storage rack 2.

[0052] According to another aspect of the present application, as shown in Figure 2 It also provides a pre-treatment device, which comprises a mounting platform, a feeding assembly 5, an opening and closing cover assembly 6 and a pipetting assembly as described above, the mounting platform has a first area 7, a second area 8 and a third area 9 arranged independently, the feeding assembly 5 is arranged on the first area 7, the pipetting assembly is arranged on the second area 8, and the opening and closing cover assembly 6 is arranged on the third area 9.

[0053] The pre-treatment device can be used for detecting and analyzing biological samples, the feeding assembly 5 in the pre-treatment device can be used for storing test tubes containing biological samples, the opening and closing cover assembly 6 can fix the test tubes and open or close the cover bodies of the test tubes, and the pipetting assembly can transfer the biological samples from the test tubes to centrifugal tubes.

[0054] By arranging the feeding assembly 5, the opening and closing cover assembly 6 and the pipetting assembly on the mounting platform respectively, the specific positions of the feeding assembly 5, the opening and closing cover assembly 6 and the pipetting assembly can be reasonably arranged, the use space of the pre-treatment device is optimized, and the pre-treatment device is arranged more compactly.

[0055] The first area 7 and the second area 8 can be arranged opposite to the third area 9, by arranging different assemblies on different areas of the mounting platform, the functions of the assemblies can be clearly distinguished, and the operator can be facilitated to identify and use. Moreover, reasonably dividing the areas on the mounting platform can more effectively utilize the space and avoid the interference between the assemblies.

[0056] The pre-treatment device of the present application comprises the pipetting assembly as described above, since the pipetting assembly has the beneficial effects as described above, the pre-treatment device comprising the pipetting assembly as described above also necessarily has the beneficial effects as described above.

[0057] In some embodiments, as shown in Figure 2 The installation platform comprises a placing table 10 and a body arranged below the placing table 10, the feeding assembly 5, the switch cover assembly 6 and the pipetting assembly are arranged on the placing table 10, and the placing table 10 is movably connected with the body.

[0058] In the above embodiment, the placing table 10 can be pulled out by the operator in a pullable manner, so as to facilitate the operation and maintenance of the feeding assembly 5, the switch cover assembly 6 and the pipetting assembly. Moreover, the placing table 10 is movably connected with the body, so as to facilitate the disassembly and replacement of the placing table 10, thereby effectively improving the convenience and practicality of the use of the installation platform.

[0059] In some embodiments, the first area 7 is provided with positioning columns (not shown in the figure), and the feeding assembly 5 is provided with grooves matched with the positioning columns, and the positioning columns are used for being inserted into the grooves.

[0060] The lower surface of the feeding assembly 5 can be formed with grooves matched with the positioning columns, and when the feeding assembly 5 is placed on the first area 7, the positioning columns can be inserted into the grooves, so as to not only realize accurate positioning of the feeding device, but also avoid displacement of the feeding device in the horizontal direction.

[0061] The number of the positioning columns can be multiple, and the multiple positioning columns can be arranged on the first area 7 in an interval manner, so as to firmly limit the feeding assembly 5 on the first area 7.

[0062] In the above embodiment, through the cooperation of the positioning columns and the grooves, the feeding assembly 5 can be quickly and conveniently placed on the specified position on the first area 7, effectively reducing the assembly time and improving the assembly efficiency. Moreover, the feeding assembly 5 can be firmly limited on the first area 7, reducing the situation that the feeding device falls and overturns due to external force, thereby effectively improving the practicality and reliability of the pretreatment device.

[0063] Although the example embodiments have been described herein with reference to the accompanying drawings, it is to be understood that the above-described example embodiments are merely exemplary and are not intended to limit the scope of the present application. Those of ordinary skill in the art can make various changes and modifications therein without departing from the scope and spirit of the present application. All such changes and modifications are intended to be included within the scope of the present application as claimed in the appended claims.

[0064] For the convenience of description, the term "connected" can be used herein to describe the relationship between one or more elements or features shown in the figures and other elements or features. It should be understood that "connected" can include direct connection or indirect connection via other elements or features, and all these cases are intended to be included herein.

[0065] It is to be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments consistent with the present application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and / or "comprising," when used in this specification, specify the presence of stated features, steps, operations, components, elements, and / or groups thereof, but do not preclude the presence or addition of one or more other features, steps, operations, components, elements, and / or groups thereof.

[0066] It should be noted that the terms "first", "second", and the like, herein do not necessarily have an either chronological or spatial relation to each other, but are used merely to distinguish between two or more objects or actions. It should be understood that the use of the term "or" in the context of this application is to be interpreted as an inclusive "or," meaning any one or any combination. Therefore, in the context of this application, "A or B" means "A, B, or both A and B." It should also be understood that, in the context of this application, the term "comprises" does not exclude the presence of other elements or additional steps.

[0067] The utility model has carried on the explanation through the above embodiment, but should understand, the above embodiment is only for example and the purpose of explanation, but not the intention of the utility model is limited in the range of described embodiment. In addition, the skilled in the art can understand that the utility model is not limited to the above embodiment, according to the teaching of the utility model, more kinds of variations and modifications can also be made, and these variations and modifications all fall within the scope of the utility model claimed. The protection scope of the utility model is defined by the attached claims and its equivalent scope.

Claims

1. A pipetting assembly, characterized in that, include: A pipetting device, comprising a first pipetting device and a second pipetting device, wherein the dimensional parameters of the first pipetting device and the dimensional parameters of the second pipetting device are different; Storage rack, wherein the storage rack is provided with a first storage position and a second storage position; and An anti-misoperation plug is provided, which is set in the first storage position. The first pipette is set in the first storage position through the anti-misoperation plug, and the second pipette is set in the second storage position. The anti-misoperation plug is used to prevent the second pipette from being inserted into the first storage position.

2. The pipetting assembly according to claim 1, characterized in that, The storage rack has an inner sidewall in the first storage position, and the anti-misoperation plug is disposed on the inner sidewall and is disposed near the upper surface of the storage rack.

3. The pipetting assembly according to claim 2, characterized in that, The storage rack is a frame structure, and the anti-misoperation plug is a plate-shaped structure. The plate surface of the anti-misoperation plug is perpendicular to the inner sidewall and is arranged parallel to the upper surface of the storage rack.

4. The pipetting assembly according to claim 2, characterized in that, The anti-misoperation plug includes a fixing part and a through hole through the fixing part. The center line of the through hole is parallel to the inner sidewall, and the first pipette is inserted through the through hole.

5. The pipetting assembly according to claim 4, characterized in that, There is a preset distance between the upper surface of the storage rack and the upper surface of the fixing part, which is smaller than the distance from the bottom of the second pipette to the upper surface of the fixing part.

6. The pipetting assembly according to claim 4, characterized in that, Both the through hole and the second pipette have circular cross-sections, and the diameter of the through hole is smaller than the diameter of the second pipette.

7. The pipetting assembly according to claim 3, characterized in that, The frame structure includes an upper cover and a side cover, with the upper cover being movably connected to the side cover via a snap-fit ​​structure.

8. A pretreatment apparatus, characterized in that, The device includes an installation platform, a feeding assembly, a cap-switching assembly, and a pipetting assembly as described in any one of claims 1 to 7. The installation platform has a first region, a second region, and a third region that are independently disposed therein. The feeding assembly is disposed on the first region, the pipetting assembly is disposed on the second region, and the cap-switching assembly is disposed on the third region.

9. The pretreatment apparatus according to claim 8, characterized in that, The installation platform includes a platform and a main body disposed below the platform. The feeding assembly, the cover opening and closing assembly, and the pipetting assembly are all disposed on the platform, and the platform is connected to the main body in a pull-out manner.

10. The pretreatment apparatus according to claim 9, characterized in that, The first area is provided with a positioning post, and the feeding component is provided with a groove adapted to the positioning post, and the positioning post is used to be inserted into the groove.

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