Constant-temperature detection instrument

By introducing a vibration device into the test kit, the reaction element is driven by a vibrating disk to perform an arc-shaped motion. Combined with a right-angle light-entry channel and a light-harvesting channel, the problem of slow reaction rate is solved, and the reaction rate and efficiency are improved.

CN223576490UActive Publication Date: 2025-11-21CHANGQI BIOTECHNOLOGY (KUNSHAN) CO LTD
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Patent Information

Application Number
CN202422846176.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-21
Publication Date
2025-11-21
Estimated Expiration
2034-11-21

AI Technical Summary

Technical Problem

In existing technologies, the reaction rate is slow due to the static setting of reagents and samples during the reaction process of detection kits.

Method used

A vibration device is used to make the reaction vessel move in an arc shape under the drive of the vibrating disk, and the reaction efficiency is improved by combining the light-incoming channel and the light-harvesting channel set at right angles.

Benefits of technology

The vibration effect of the vibrating device significantly improves the reaction rate and reaction efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of detection kits, in particular to a constant-temperature detection instrument which comprises a shell and a reaction block, a plurality of containing grooves are formed in the reaction block, reaction parts are arranged in the containing grooves, vibration discs are arranged on the lower sides of the containing grooves, the upper ends of the reaction parts are abutting ends, and the lower ends of the reaction parts are abutting ends. The lower end of the reaction piece abuts against the vibration disc, and the abutting end of the reaction piece at least makes arc-shaped movement in the circumferential direction. The reaction device has the following effects that the reaction part serving as a reaction part is placed in the shell to carry out conventional reaction, and in the reaction process, in a certain time period or in multiple time periods, the vibration effect is generated through the vibration disc, so that the lower end of the reaction part generates corresponding arc-shaped motion, internal substances are vibrated, and the reaction effect is improved. And the upper end of the reaction part is used as a fixed point, so that the lower side does loopback movement, and the reaction efficiency is improved.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of detection kits, in particular to a constant temperature detection instrument. BACKGROUND

[0002] In the field of detection kits, a certain specific substance is detected by mixed detection, for example, normal constant temperature nucleic acid rapid detection technology, which relies on recombination enzymes, single-stranded DNA binding proteins, DNA polymerases and specific primer probes in the system to quickly complete the nucleic acid amplification reaction at normal constant temperature (37-42 DEG C). With the accumulation of amplification products, specific molecular probes release fluorescent signals under the action of exonuclease, and real-time monitoring or end-point detection of target fragment amplification is realized using a fluorescence detection device.

[0003] However, in the actual detection process, it is found that the reagents and samples are placed together and left to react, and the overall reaction rate is slow. Practical new type content

[0004] In order to improve the reaction rate by vibration, the present application provides a detection vibration device.

[0005] The constant temperature detection instrument provided by the present application adopts the following technical scheme: a constant temperature detection instrument, comprising a shell and a reaction block, a plurality of accommodating grooves are arranged in the reaction block, a reaction piece is arranged in each accommodating groove, a vibration disc is arranged at the lower side of each accommodating groove, the upper end of the reaction piece is a contact end, the lower end of the reaction piece is in contact with the vibration disc, and the contact end of the reaction piece moves in an arc shape at least along the circumference.

[0006] By adopting the above technical scheme, the reaction piece as a reaction part is placed in the shell to perform a conventional reaction. In the reaction process, the lower end of the reaction piece is subjected to corresponding arc movement by the vibration disc to generate a shaking effect, so as to shake the internal substances, and the upper end of the reaction piece serves as a fixed point to make the lower side move in a loop, so as to improve the reaction efficiency.

[0007] Preferably, the reaction block is provided with a light inlet channel and a light trapping channel which are connected to the accommodating grooves, and the light inlet channel and the light trapping channel are arranged at right angles.

[0008] By adopting the above technical scheme, light will be shot into and irradiated on the lower side of the reaction piece through the light inlet channel, and the reflected light will be received by the light trapping channel, and the two are arranged at right angles, which will reduce the influence of the entering light on the reflection result.

[0009] Preferably, the accommodating grooves and the circumferential side of the reaction piece have a gap.

[0010] By adopting the technical scheme, the existence of the gap increases the overall shakable space.

[0011] Preferably, the accommodating groove comprises a first section, a transition section and a second section, the cross-sectional area of the first section is greater than that of the second section, and the transition section is a slope.

[0012] By adopting the technical scheme, the first section is used to place the lower end of the reaction part first, facilitating insertion, and then guiding it through the transition section, facilitating the placement of the overall reaction part.

[0013] Preferably, the bottom of the reaction part is oblate, and the lower side of the accommodating groove is adapted in shape.

[0014] By adopting the technical scheme, the oblate lower end can form a foolproof effect on the whole to fix the angle during insertion.

[0015] Preferably, the shell is rotatably connected with a closure cover, and the inner side of the closure cover is used to abut against the abutting end.

[0016] Preferably, the lower side of the vibration disc is fixedly provided with a floating disc, and the floating disc and the shell have a floating spring therebetween.

[0017] By adopting the technical scheme, the closure cover can form a certain pressure effect on the reaction part, thereby forming a pre-tightening force.

[0018] Preferably, the light inlet channel is directed to the larger face of the reaction part, and the light trapping channel is directed to the smaller face of the reaction part.

[0019] By adopting the technical scheme, the light can be irradiated on the reaction part in the largest possible range through the larger face.

[0020] Preferably, the upper side of the vibration disc has a step inserted into the accommodating groove.

[0021] By adopting the technical scheme, the step and the accommodating groove cooperate to form a light-shielding effect.

[0022] In summary, the present application has at least one of the following beneficial technical effects: the reaction part as a reaction part is placed in the shell, a conventional reaction is carried out, and in the process of the reaction, the lower end of the reaction part generates a corresponding arc-shaped motion through the vibration disc to generate a shaking effect in a certain time period or multiple time periods, so as to shake the internal substances, and the upper end of the reaction part as a fixed point makes the lower side do a circular motion, so as to improve the reaction efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0023] Figure 1 is a structural schematic diagram of the present application;

[0024] Figure 2 is the internal structure schematic diagram of the present application;

[0025] Figure 3 is the sectional view of the reaction block;

[0026] Figure 4 is the structure schematic diagram of the reaction piece;

[0027] Figure 5 is the connection relationship schematic diagram of the vibrating disc and the floating disc.

[0028] Legend: 100, the shell; 110, the reaction block; 111, the accommodation groove; 112, the reaction piece; 113, the vibrating disc; 114, the abutting end; 115, the first section; 116, the transition section; 117, the second section; 121, the light inlet channel; 122, the light trapping channel; 123, the step; 124, the closed cover; 125, the eccentric motor; 130, the floating disc; 131, the floating spring; 132, the mounting bottom plate; 133, the floating guide rod. DETAILED DESCRIPTION

[0029] The present application is further described in detail below in conjunction with the accompanying drawings.

[0030] A constant temperature detection instrument, referring to Figure 1 , Figure 2 , comprising a shell 100 and a reaction block 110, the reaction block 110 is provided with a plurality of accommodation grooves 111, the accommodation grooves 111 are provided with reaction pieces 112, the accommodation grooves 111 have vibrating discs 113 on the lower side, the upper end of the reaction piece 112 is an abutting end 114, the lower end of the reaction piece 112 is abutting to the vibrating disc 113, and the abutting end 114 of the reaction piece 112 at least moves in an arc shape along the circumference.

[0031] Referring to Figure 2 , Figure 3 , Figure 4 , the accommodation groove 111 comprises a first section 115, a transition section 116 and a second section 117, the cross-sectional area of the first section 115 is larger than that of the second section 117, and the transition section 116 is a slope. In the present embodiment, the reaction piece 112 is a reaction tube, and the overall shape is adapted to the accommodation groove 111. The lower end of the reaction piece 112 is a flat round shape, and the corresponding second section 117 is also an adapted shape.

[0032] The reaction block 110 is provided with a light inlet channel 121 and a light capturing channel 122 which communicate with the accommodating groove 111, and the light inlet channel 121 and the light capturing channel 122 are at right angles. Specifically, the light inlet channel 121 and the light capturing channel 122 are both located in the second section 117, and the light inlet channel 121 faces the larger surface of the reaction piece 112, and the light capturing channel 122 faces the smaller surface of the reaction piece 112. The light inlet channel 121 collects light through a larger area, and enables the internal reactants to react better, and meanwhile, when the light capturing channel 122 receives light, the right-angle staggered arrangement can reduce the error influence. The oblate lower end can enable the reaction piece 112 to be inserted in the correct direction, and enable the reactants to receive light better.

[0033] With reference to Figure 2 , Figure 3 , Figure 5 The vibration disc 113 is arranged on the shell 100 and located below the reaction piece 112, the lower side of the accommodating groove 111 is communicatively arranged, and the vibration disc 113 has a step 123 which is inserted into the accommodating groove 111 on the upper side, the step 123 can close the lower side, but the circumferential side of the step 123 and the inner wall of the accommodating groove 111 have a space for avoiding when vibrating. Meanwhile, the shell 100 is rotationally connected with a closing cover 124, the inner side of the closing cover 124 is used for pressing against the abutting end 114. And the accommodating groove 111 and the circumferential side of the reaction piece 112 have a gap, when the closing cover 124 is closed, the abutting end 114 will be fixed at the abutting end 114, and the abutting end 114 moves synchronously with the vibration disc 113.

[0034] In the embodiment, the vibration disc 113 is internally provided with an eccentric motor 125, and the vibration disc 113 is wrapped outside the eccentric wheel of the eccentric motor 125, when the eccentric motor 125 moves, the circumferential eccentric vibration of the eccentric wheel will be transmitted to the vibration disc 113, so that the abutting end 114 moves in an arc shape in the circumferential direction, to realize the effect of vibrating.

[0035] In order to cooperate with the closing cover 124 to limit the reaction piece 112 in the reaction block 110, the vibration disc 113 is fixedly provided with a floating disc 130 on the lower side, and the floating disc 130 and the shell 100 have a floating spring 131 therebetween. Specifically, the shell 100 has a mounting bottom plate 132 on the bottom, the mounting bottom plate 132 has a floating guide rod 133 thereon, the floating guide rod 133 penetrates through the floating disc 130, and the floating spring 131 is sleeved on the floating guide rod 133, and the two ends thereof abut against the shell 100 and the floating disc 130 respectively. During the closing process of the closing cover 124, the floating spring 131 will be compressed in the axial direction, so that the reaction piece 112 can be limited, and during the working process of the vibration disc 113, the floating spring 131 can realize a certain axial movement space.

[0036] The embodiments of the present application are preferred embodiments of the present application, and are not intended to limit the protection scope of the present application, and thus: any equivalent changes made according to the structure, shape, principle of the present application should be covered within the protection scope of the present application.

Claims

1. A constant temperature detection instrument, comprising a housing (100) and a reaction block (110), characterized in that: The reaction block (110) is provided with a plurality of receiving grooves (111), and a reaction element (112) is provided in the receiving groove (111). A vibrating disk (113) is provided on the lower side of the receiving groove (111). The upper end of the reaction element (112) is a contact end (114), and the lower end of the reaction element (112) is in contact with the vibrating disk (113). The contact end (114) of the reaction element (112) moves in an arc shape at least in the circumferential direction.

2. The constant temperature detection instrument according to claim 1, characterized in that: The reaction block (110) is provided with a light-inlet channel (121) and a light-harvesting channel (122) that connect to the accommodating groove (111). The light-inlet channel (121) and the light-harvesting channel (122) are at right angles.

3. The constant temperature detection instrument according to claim 2, characterized in that: The receiving groove (111) has a gap with the periphery of the reaction element (112).

4. The constant temperature detection instrument according to claim 3, characterized in that: The receiving groove (111) includes a first section (115), a transition section (116), and a second section (117). The cross-sectional area of ​​the first section (115) is larger than that of the second section (117), and the transition section (116) is an inclined surface.

5. A constant temperature detection instrument according to claim 4, characterized in that: The bottom of the reaction element (112) is flat and round, and the second segment (117) is a matching shape.

6. A constant temperature detection instrument according to claim 5, characterized in that: A closing cover (124) is rotatably connected to the housing (100), and the inner side of the closing cover (124) is used to press against the contact end (114).

7. A constant temperature detection instrument according to claim 6, characterized in that: A floating disk (130) is fixedly installed on the lower side of the vibratory disk (113), and a floating spring (131) is provided between the floating disk (130) and the housing (100).

8. A constant temperature detection instrument according to claim 7, characterized in that: The light-gathering channel (121) faces the larger surface of the reactant (112), and the light-harvesting channel (122) faces the smaller surface of the reactant (112).

9. A constant temperature detection instrument according to claim 8, characterized in that: The vibratory plate (113) has a step (123) on its upper side that inserts into the receiving groove (111).