Extraction device for chemical drug impurity detection

Abstract

The utility model discloses an extraction device for chemical drug impurity detection. The extraction device comprises a drug impurity centrifugal extraction mechanism and a jacking mechanism arranged on the surfaces of a shell and a centrifugal extraction disc. The medicine impurity centrifugal extraction mechanism comprises a shell, a cover plate, a driving part and a centrifugal extraction disc, the cover plate is rotationally connected to the top of the shell through a damping rotating shaft, the driving part is installed on the inner wall of the shell, and the centrifugal extraction disc is installed on the surface of the driving part. The jacking mechanism comprises a transmission part and a jacking part. Solid particles or liquid drops in a mixture are separated according to the density and the size by means of centrifugal force generated by high-speed rotation, a test tube after centrifugation can be partially jacked out through the jacking mechanism, an inspector can conveniently take out the test tube, the test tube can be taken out without a tweezers tool after centrifugation is completed or when the test tube needs to be taken out by misplacement, and the operation is convenient. The head of the test tube can be exposed during opening and moved into the test tube during closing.

Description

TECHNICAL FIELD

[0001] The utility model relates to centrifugal extraction technical field, especially a kind of extraction device for chemical medicine impurity detection. BACKGROUND

[0002] Chemical medicine impurity detection extraction centrifugation is a commonly used technology, for separating and detecting impurities from drug samples, centrifugal technology is a technology using centrifugal force to realize material separation, widely used in biology, chemistry, medicine and other fields, plays an important role in the process of separating impurities in extract.

[0003] Through search, the name of a kind of experimental high-speed centrifuge of announcement No. CN212284473U, by research and analysis, it is found that, although it has the advantage of carrying conveniently, but, to some extent, there are still the following shortcomings.

[0004] For example, when the test tube with small size and short length is placed for centrifugation, it cannot be exposed, and it is not convenient for the inspector to take it out, and when the centrifugation is completed or placed incorrectly, it needs to be taken out with the help of tweezers, and the head of the test tube cannot be exposed when it is opened and moved into the inside when it is closed to facilitate personnel to take it down, in order to solve the above technical problems, therefore, we design a kind of extraction device for chemical medicine impurity detection. SUMMARY

[0005] In view of the shortcomings of the prior art described above, the purpose of the utility model is to provide an extraction device for chemical medicine impurity detection to solve the problem that when the test tube is centrifuged with small size and short length, it needs to be taken out with the help of tweezers.

[0006] An extraction device for chemical medicine impurity detection comprises a drug impurity centrifugal extraction mechanism and a jacking mechanism installed on the surface of the casing and the centrifugal extraction disc.

[0007] The drug impurity centrifugal extraction mechanism comprises a casing, a cover plate, a driving part and a centrifugal extraction disc, the cover plate is rotatably connected to the top of the casing by a damping shaft, the driving part is installed on the inner wall of the casing, and the centrifugal extraction disc is installed on the surface of the driving part.

[0008] The jacking mechanism comprises a transmission part and a jacking part, the transmission part is arranged on the surface of the cover plate and the casing, and the jacking part is arranged on the surface of the centrifugal extraction disc and the driving part.

[0009] As a further improvement of the above-mentioned scheme, the driving part comprises a support plate and a rotating rod, both ends of the support plate are fixedly connected to the inner wall of the casing, the rotating rod is rotatably connected to the surface of the support plate by a bearing, and the upper end of the rotating rod is fixedly connected to the bottom of the centrifugal extraction disc.

[0010] As further improvement of the above-mentioned scheme, the bottom of the shell cavity is fixedly connected with a motor through a bolt, the rotating shaft of the motor and the lower end of the rotating rod are both fixedly sleeved with a belt disc, and the surfaces of the two belt discs are drivingly connected with a belt.

[0011] As further improvement of the above-mentioned scheme, the transmission member comprises a frame, a pressing plate, a connecting plate and an extruding plate, the frame is fixedly connected on the surface of the shell, the pressing plate is slidingly penetrated through the top of the frame, the connecting plate is rotatably connected with the top of the cover plate and the top of the pressing plate through rotating shafts at two ends, and the extruding plate is slidingly connected in the frame.

[0012] As further improvement of the above-mentioned scheme, the bottom of the extruding plate is fixedly connected with a limiting block, the surface of the frame is provided with a limiting hole matched with the limiting block, and the limiting block is slidingly connected in the limiting hole.

[0013] As further improvement of the above-mentioned scheme, the jacking member comprises a jacking rod, a rubber pad, a positioning rod, three ring plates and a connecting block, the jacking rod is slidingly penetrated through the surface of the centrifugal extraction disc, the rubber pad is fixedly connected at one end of the jacking rod, the positioning rod is slidingly penetrated through the top of the supporting plate, the three ring plates are fixedly connected through the connecting block, and the positioning rod is fixedly connected at the bottom of the ring plates.

[0014] As further improvement of the above-mentioned scheme, the end of the jacking rod away from the rubber pad is fixedly connected with a jacking ball, and the surface of the connecting block is in contact with the surface of the extruding plate.

[0015] As further improvement of the above-mentioned scheme, the surface of the centrifugal extraction disc is provided with a placing groove, and the top of the cover plate is embeddedly connected with an observation window.

[0016] As further improvement of the above-mentioned scheme, the surface of the shell is rotatably connected with a box door through a hinge, and the surface of the cover plate is fixedly connected with a handle.

[0017] Compared with the prior art, the centrifugal extraction mechanism can centrifugally separate the medicine in the test tube, the centrifugal force generated by high-speed rotation can separate the solid particles or liquid drops in the mixture according to the density and size, the jacking mechanism can jacking out part of the test tube after centrifugation, and the test personnel can conveniently take out the test tube. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 Fig. 1 is a perspective view of the extraction device provided by the utility model.

[0019] Figure 2It is the partial section perspective structural diagram of the extraction device provided by the utility model.

[0020] Figure 3 It is the partial section perspective structural diagram of the extraction device provided by the utility model. Figure 2 The enlarged view of A.

[0021] Figure 4 It is the partial section perspective structural diagram of the extraction device provided by the utility model. Figure 2 The enlarged view of B.

[0022] Figure 5 It is the perspective structural diagram of the support plate and the positioning rod in the extraction device.

[0023] Figure 6 It is the perspective structural diagram of the centrifugal extraction disc and the top ball in the extraction device.

[0024] Main element symbol explanation

[0025] 100, drug impurity centrifugal extraction mechanism, 101, shell, 102, cover plate, 103, driving piece, 104, centrifugal extraction disc, 105, placing groove, 106, observation window, 107, box door, 200, jacking mechanism, 201, transmission piece, 202, jacking piece, 103a, support plate, 103b, rotating rod, 103c, motor, 103d, belt disc, 103e, belt, 201a, frame, 201b, pressing plate, 201c, connecting plate, 201d, extrusion plate, 201e, limiting block, 201f, limiting hole, 202a, jacking rod, 202b, rubber pad, 202c, positioning rod, 202d, ring plate, 202e, connecting block, 202f, top ball.

[0026] The above main element symbol explanation is further explained in detail in combination with the drawings and the specific embodiment. Specific embodiment

[0027] In order to make the purpose, technical scheme and advantages of the utility model more clear and obvious, the following will be combined with examples to further explain the utility model. The additional aspects and advantages of the utility model will be partly given in the following description, partly will become obvious from the following description, or will be understood by the practice of the utility model. It should be understood that the following description is only used to explain the utility model, and is not used to limit the utility model.

[0028] The specific embodiment of the utility model is explained in detail below. Example 1

[0029] Refer to Figures 1-2The embodiment provides an extraction device for chemical medicine impurity detection, which comprises a medicine impurity centrifugal extraction mechanism 100 and a jacking mechanism 200, medicine in a test tube can be centrifugally separated through the medicine impurity centrifugal extraction mechanism 100, and the test tube can be ejected after centrifugation through the jacking mechanism 200, so that an inspector can conveniently take out the test tube.

[0030] The medicine impurity centrifugal extraction mechanism 100 comprises a shell 101, a cover plate 102, a driving piece 103 and a centrifugal extraction disc 104, the cover plate 102 is rotationally connected to the top of the shell 101 through a damping rotating shaft, the driving piece 103 is installed on the inner wall of the shell 101, and the centrifugal extraction disc 104 is installed on the surface of the driving piece 103. In the embodiment, the damping rotating shaft arranged between the cover plate 102 and the shell 101 can hover at any position and is not affected by the force of the transmission piece 201, the driving piece 103 rotationally drives the centrifugal extraction disc 104, and the medicine in the test tube placed in the interior is centrifuged.

[0031] The jacking mechanism 200 is installed on the surface of the shell 101 and the centrifugal extraction disc 104, and comprises a transmission piece 201 and a jacking piece 202, the transmission piece 201 is arranged on the surface of the cover plate 102 and the shell 101, and the jacking piece 202 is arranged on the surface of the centrifugal extraction disc 104 and the driving piece 103. In the embodiment, the transmission piece 201 is driven to drive the jacking piece 202 through the rotational driving of the cover plate 102, and the components on the jacking piece 202 and the transmission piece 201 are reset under the action of gravity during the closing process of the cover plate 102. Embodiment 2

[0032] Reference Figures 2-6 The embodiment is based on the previous embodiment. The driving piece 103 comprises a support plate 103a and a rotating rod 103b, both ends of the support plate 103a are fixedly connected to the inner wall of the shell 101, the rotating rod 103b is rotationally connected to the surface of the support plate 103a through a bearing, and the upper end of the rotating rod 103b is fixedly connected to the bottom of the centrifugal extraction disc 104.

[0033] The lower end of the rotating rod 103b extends to the bottom of the support plate 103a, the rotating rod 103b is fixedly connected to the inner ring of the bearing sleeved on the surface thereof, and the support plate 103a is fixedly connected to the outer surface of the bearing sleeved on the rotating rod 103b.

[0034] The bottom of the inner cavity of the shell 101 is fixedly connected with a motor 103c through bolts, the rotating shaft of the motor 103c and the lower end of the rotating rod 103b are fixedly sleeved with a belt disc 103d, and the surfaces of the two belt discs 103d are drivingly connected with a belt 103e.

[0035] The two belt pulleys 103d have the same size, and the belt pulley 103d on the motor 103c is driven to rotate, and then the belt 103e is driven to rotate the rotating rod 103b and the belt pulley 103d thereon, so that the rotating rod 103b and the centrifugal extraction disc 104 rotate.

[0036] The transmission member 201 comprises a frame 201a, a pressing plate 201b, a connecting plate 201c and an extrusion plate 201d. The frame 201a is fixedly connected to the surface of the shell 101. The pressing plate 201b is slidably penetrated through the top of the frame 201a. The two ends of the connecting plate 201c are rotatably connected to the top of the cover plate 102 and the top of the pressing plate 201b through rotating shafts respectively. The extrusion plate 201d is slidably connected in the frame 201a.

[0037] The lower end of the pressing plate 201b is provided with a slope. The two ends of the extrusion plate 201d are provided with slopes. The surface of the connecting plate 201c is provided with a slope. The rotation of the cover plate 102 can drive the connecting plate 201c to rotate and move, thereby driving the pressing plate 201b to move, so as to extrude or separate the extrusion plate 201d, and then the extrusion plate 201d extrudes or separates the connecting block 202e, so as to lift the ring plate 202d, and when separated, the connecting block 202e extrudes and resets the extrusion plate 201d under the action of the gravity of the ring plate 202d and the connecting block 202e.

[0038] The bottom of the extrusion plate 201d is fixedly connected with a limiting block 201e. The surface of the frame 201a is provided with a limiting hole 201f matched with the limiting block 201e. The limiting block 201e is slidably connected in the limiting hole 201f.

[0039] The limiting block 201e and the limiting hole 201f limit the movement of the extrusion plate 201d within a certain range, and the extrusion plate 201d will not be separated from the frame 201a.

[0040] The lifting member 202 comprises a lifting rod 202a, a rubber pad 202b, a positioning rod 202c, a ring plate 202d and a connecting block 202e. The lifting rod 202a is slidably penetrated through the surface of the centrifugal extraction disc 104. The rubber pad 202b is fixedly connected to one end of the lifting rod 202a. The positioning rod 202c is slidably penetrated through the top of the supporting plate 103a. The number of the ring plates 202d is three, and they are fixedly connected through the connecting block 202e. The positioning rod 202c is fixedly connected to the bottom of the ring plate 202d.

[0041] The cross section of the top rod 202a is square, the rubber pad 202b is limited by the top rod 202a, and the rubber pad 202b and the top ball 202f are indirectly connected, synchronous movement is realized, the test tube can be placed and buffered by the rubber pad 202b, the ring plate 202d is arranged, a plurality of top balls 202f can be simultaneously acted on in the rising process of the ring plate 202d, the number of the positioning rods 202c is two, the ring plate 202d is guided and limited, so that the ring plate 202d cannot be inclined, and the plurality of ring plates 202d are connected by the connecting plate 201c, so that the ring plates 202d move together.

[0042] The top ball 202f is fixedly connected to the end, away from the rubber pad 202b, of the top rod 202a, and the surface of the connecting block 202e is in contact with the surface of the extrusion plate 201d. The contact friction between the top rod 202a and the ring plate 202d is reduced by the top ball 202f, and the ring plate 202d moves smoothly when the ring plate 202d lifts the top ball 202f.

[0043] The surface of the centrifugal extraction disc 104 is provided with a plurality of placing grooves 105, and the top of the cover plate 102 is inlaidly connected with an observation window 106. The number of the placing grooves 105 is several, a plurality of test tubes can be placed, and the inside can be observed when the cover plate 102 is closed through the observation window 106.

[0044] The surface of the shell 101 is hingedly connected with a box door 107, and the surface of the cover plate 102 is fixedly connected with a handle. The cover plate 102 is conveniently rotated and opened by the handle, and the box door 107 is conveniently opened for internal maintenance.

[0045] In use, the cover plate 102 is partially rotated and opened by holding the handle, the connecting plate 201c is rotated and moved, the lower pressing plate 201b is moved downward, the extrusion plate 201d is extruded and moved, the connecting block 202e, the ring plate 202d and the positioning rod 202c are extruded and moved upward by the extrusion plate 201d, the top ball 202f is lifted and moved along the top rod 202a, the top rod 202a is moved into the placing groove 105, the rubber pad 202b is moved, the test tube is inserted into the placing groove 105, and the rubber pad 202b supports and buffers the bottom.

[0046] Then the cover plate 102 is closed under the action of the connecting plate 201c to move the lower pressing plate 201b upwards to reset, under the action of the ring plate 202d and the connecting block 202e gravity, the connecting block 202e is pressed against the extrusion plate 201d to move it to reset, and then the ring plate 202d and the connecting block 202e are moved downwards to reset, and the top rod 202a, the top ball 202f and the rubber pad 202b are reset, at this time the top ball 202f is not in contact with the ring plate 202d, the operation of the control motor 103c is driven by the belt pulley 103d and the belt 103e, the rotating rod 103b and the centrifugal extraction disc 104 are rotated, and then the medicine in the test tube is centrifuged, the centrifugal force generated by high-speed rotation will separate the solid particles or liquid drops in the mixture according to the density and size, and the dissolved substances are separated from the solids by layering, so as to facilitate subsequent drug impurity detection by detection equipment, after centrifugation, the motor 103c is turned off, the cover plate 102 is completely opened, and then the top rod 202a and the rubber pad 202b are moved obliquely upwards, the test tube in the placing groove 105 is pushed upwards, and the exposed head can be conveniently taken out by the inspector.

[0047] In summary, the drug impurity centrifugal extraction mechanism 100 can centrifuge and separate the medicine in the test tube, and the jacking mechanism 200 can push out part of the test tube after centrifugation, which is convenient for the inspector to take out. Compared with the prior art, when the centrifugation is completed or the test tube is placed incorrectly and needs to be taken out, it does not need to be taken out with the help of tweezers, and the test tube head can be exposed when it is opened and moved into the inside when it is closed.

[0048] The above embodiments are only preferred embodiments of the present application, and any simple modification, modification and alternative change of the above embodiments according to the technical essence of the present application are within the scope of the technical scheme of the present application.

Claims

1. An extraction device for detecting a chemical drug impurity, characterized by: The centrifugal extraction mechanism for drug impurities comprises a shell (101), a cover plate (102), a driving element (103) and a centrifugal extraction disc (104), the cover plate (102) is rotationally connected to the top of the shell (101) through a damping shaft, the driving element (103) is installed on the inner wall of the shell (101), and the centrifugal extraction disc (104) is installed on the surface of the driving element (103). The driving element (103) comprises a support plate (103a) and a rotating rod (103b), both ends of the support plate (103a) are fixedly connected to the inner wall of the shell (101), the rotating rod (103b) is rotationally connected to the surface of the support plate (103a) through a bearing, and the upper end of the rotating rod (103b) is fixedly connected to the bottom of the centrifugal extraction disc (104). The bottom of the inner cavity of the shell (101) is fixedly connected with a motor (103c) through bolts, the rotating shaft of the motor (103c) and the lower end of the rotating rod (103b) are fixedly sleeved with a belt disc (103d), and the surfaces of the two belt discs (103d) are drivingly connected with a belt (103e).

2. The extraction device for detecting chemical drug impurities according to claim 1, characterized by: The driving element (201) comprises a frame (201a), a pressing plate (201b), a connecting plate (201c) and an extrusion plate (201d), the frame (201a) is fixedly connected to the surface of the shell (101), the pressing plate (201b) is slidingly penetrated into the top of the frame (201a), the connecting plate (201c) is rotationally connected to the top of the cover plate (102) and the top of the pressing plate (201b) through shafts at both ends, and the extrusion plate (201d) is slidingly connected in the frame (201a).

3. The extraction device for detecting chemical drug impurities according to claim 2, characterized by: The bottom of the extrusion plate (201d) is fixedly connected with a limiting block (201e), the surface of the frame (201a) is provided with a limiting hole (201f) matched with the limiting block (201e), and the limiting block (201e) is slidingly connected in the limiting hole (201f).

4. The extraction device for detecting chemical drug impurities according to claim 1, characterized by: The jacking element (202) comprises a jacking rod (202a), a rubber pad (202b), a positioning rod (202c), a ring plate (202d) and a connecting block (202e), the jacking rod (202a) is slidingly penetrated into the surface of the centrifugal extraction disc (104), the rubber pad (202b) is fixedly connected to one end of the jacking rod (202a), the positioning rod (202c) is slidingly penetrated into the top of the support plate (103a), the number of the ring plates (202d) is three, the ring plates (202d) are fixedly connected through the connecting block (202e) between the ring plates (202d), and the positioning rod (202c) is fixedly connected to the bottom of the ring plate (202d).

5. The extraction device for detecting chemical drug impurities according to claim 4, characterized by: ​ 6. The extraction device for detecting chemical drug impurities according to claim 1, characterized by: ​ 7. The extraction device for detecting chemical drug impurities according to claim 6, characterized by: The top rod (202a) is fixedly connected with a top ball (202f) at one end away from the rubber pad (202b), and the surface of the connecting block (202e) is in contact with the surface of the extrusion plate (201d).

8. The extraction device for detecting chemical drug impurities according to claim 1, characterized by: The surface of the centrifugal extraction disc (104) is provided with a placing groove (105), and the top of the cover plate (102) is embeddedly connected with an observation window (106).

9. The extraction device for detecting chemical drug impurities according to claim 1, characterized by: The surface of the shell (101) is rotatably connected with a box door (107) through a hinge, and the surface of the cover plate (102) is fixedly connected with a handle.

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