Preparation device for apolipoprotein B

Abstract

The utility model discloses a preparation device for apolipoprotein B, and relates to the technical field of protein preparation. The preparation device comprises a centrifugal motor, the driving end of the centrifugal motor is connected with a driving shaft which vertically extends upwards, the driving shaft is connected with a centrifugal turntable, and the centrifugal turntable is provided with a plurality of centrifugal grooves for placing test tubes; the number of the sealing cavities is the same as that of the centrifugal grooves, one ends of the sealing cavities communicate with the interiors of the centrifugal grooves, piston plates are slidably installed in the sealing cavities, and the piston plates are connected with pushing rods capable of extending into the centrifugal grooves; the air supply part is arranged on the centrifugal rotating disc and used for supplying air into the sealing cavity so as to drive the piston plate to push the jacking rod to slide towards the interior of the centrifugal groove. The test tubes placed in the centrifugal groove can be conveniently ejected out, so that the test tubes are more convenient to take and place.

Description

Technical Field

[0001] This invention relates to the field of protein preparation technology, specifically to a formulation device for apolipoprotein B. Background Technology

[0002] Apolipoprotein B is synthesized by the liver and is the main structural protein of low-density lipoprotein cholesterol (LDL-CHOL), accounting for about 97% of the total protein content of LDL-CHOL. The measurement of ApoB can directly reflect the level of LDL-CHOL. Elevated apolipoprotein B levels are a risk factor for coronary heart disease and are positively correlated with the incidence of atherosclerosis and coronary heart disease. That is, the higher the level of apolipoprotein B, the greater the risk of coronary heart disease. In the preparation process, apolipoprotein B needs to be extracted from serum by centrifugation.

[0003] Currently, there are some inconveniences in the use of general centrifuges.

[0004] After centrifuging apolipoprotein B, the test tubes containing apolipoprotein B need to be removed from the centrifuge tank. However, the existing centrifuge tanks have a small diameter, making it difficult to remove the test tubes. Each time, staff have to carefully reach into the centrifuge tank to retrieve the test tubes. On the one hand, the limited operating space makes it difficult to accurately grasp the test tubes, which can easily lead to slipping and increase the risk of sample damage. On the other hand, the inconvenience of operation consumes a lot of time and effort, reducing work efficiency.

[0005] In view of the above, this application is hereby submitted. Utility Model Content

[0006] The purpose of this invention is to provide a formulation device for apolipoprotein B to solve the problems mentioned in the background art.

[0007] To solve the above-mentioned technical problems, this utility model provides a formulation device for apolipoprotein B, comprising:

[0008] A centrifugal motor has a drive shaft that extends vertically upward connected to its drive end. A centrifugal disc is connected to the drive shaft, and the centrifugal disc has multiple centrifugation troughs for placing test tubes.

[0009] The sealed cavity has the same number as the centrifuge tank, and one end of it is connected to the inside of the centrifuge tank. A piston plate is slidably installed inside the sealed cavity, and a push rod that can extend into the centrifuge tank is connected to the piston plate.

[0010] An air supply component, located on the centrifugal turntable, is used to supply air into the sealed cavity to drive the piston plate to push the push rod into the centrifugal tank.

[0011] Furthermore, the gas supply component includes

[0012] A flexible airbag is attached to the outer wall of the centrifugal disc;

[0013] The airflow channel is located inside the centrifugal disc, with one end connected to the piston plate and the other end connected to the flexible airbag.

[0014] Furthermore, a pressure sleeve is provided on the outside of the centrifugal turntable, and the pressure sleeve can slide along the outside of the centrifugal turntable.

[0015] Furthermore, a rubber column is connected to the end of the push rod away from the piston plate, and the outer diameter of the rubber column is the same as the outer diameter of the push rod.

[0016] Furthermore, it also includes a base, the base having an internal mounting cavity, and the centrifugal motor being fixedly mounted inside the mounting cavity.

[0017] Furthermore, multiple centrifugal tanks are arranged in a circumferential array on the centrifugal turntable, and each centrifugal tank is inclined, and the top surface of the base is formed with a frustum groove communicating with the centrifugal tank.

[0018] Furthermore, the top surface of the centrifugal turntable is provided with a sealing cap, and the bottom surface of the sealing cap is provided with a flexible silicone plug that can be inserted into the frustum groove.

[0019] Furthermore, the top surface of the sealing cover is provided with a knob, the bottom surface of the sealing cover is provided with a limiting ring, the top surface of the centrifugal turntable is provided with a limiting groove, and the limiting ring is threaded into the inside of the limiting groove.

[0020] Compared with the prior art, the beneficial effects of this utility model are:

[0021] 1. In this utility model, the air inside the flexible airbag can be squeezed into the airflow channel and then transported to the sealed cavity by the airflow channel. The air entering the sealed cavity will push the piston plate and the push rod to slide into the centrifuge tank, thereby making it easier to push out the test tubes placed inside the centrifuge tank, making it more convenient to pick up and put in the test tubes.

[0022] 2. In this utility model, the knob makes it easy to lift the sealing cover and place it on the centrifuge turntable. The combination of the limiting ring and the limiting groove can fix the sealing cover on the centrifuge turntable, preventing the sealing cover from falling off the centrifuge turntable during centrifugation. Attached Figure Description

[0023] Figure 1 This is a front view structural diagram of the present utility model;

[0024] Figure 2 This is a cross-sectional structural diagram of the present invention;

[0025] Figure 3 This is a schematic diagram of the centrifugal turntable in this utility model;

[0026] Figure 4 This is a schematic diagram of the sealing cap structure in this utility model.

[0027] In the diagram: 1. Base; 2. Centrifugal motor; 3. Drive shaft; 4. Centrifugal turntable; 5. Centrifugal tank; 6. Sealing cap; 7. Knob; 8. Flexible silicone plug; 9. Limiting ring; 10. Limiting groove; 11. Sealing cavity; 12. Piston plate; 13. Push rod; 14. Flexible airbag; 15. Airflow channel; 16. Pressure sleeve. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] Please see Figures 1-4 This utility model provides a technical solution: a formulation device for apolipoprotein B, comprising...

[0030] Centrifugal motor 2, whose drive end is connected to a vertically upward extending drive shaft 3, a centrifugal turntable 4 is connected to the drive shaft 3, and a plurality of centrifugal troughs 5 for placing test tubes are opened on the centrifugal turntable 4.

[0031] The number of sealed cavities 11 is the same as that of centrifuge tanks 5, and one end of the sealed cavity 11 is connected to the inside of centrifuge tank 5. A piston plate 12 is slidably installed inside the sealed cavity 11, and a push rod 13 that can extend into the inside of centrifuge tank 5 is connected to the piston plate 12.

[0032] An air supply component, mounted on the centrifugal disc 4, supplies air to the sealed cavity 11 to drive the piston plate 12 to push the push rod 13 into the centrifugal tank 5; the air supply component includes...

[0033] Flexible airbag 14 is attached to the outer wall of centrifugal disc 4;

[0034] The airflow channel 15 is located inside the centrifugal turntable 4, with one end connected to the piston plate 12 and the other end connected to the flexible airbag 14.

[0035] Specifically, by squeezing the flexible airbag 14, the air inside can be squeezed into the airflow channel 15, and then transported to the sealed cavity 11 by the airflow channel 15. The air entering the sealed cavity 11 will push the piston plate 12 and the push rod 13 to slide into the centrifuge tank 5, thereby facilitating the ejection of the test tubes placed inside the centrifuge tank 5, making it more convenient to pick up and put down the test tubes.

[0036] See Figure 1 and Figure 2 A pressure sleeve 16 is provided on the outside of the centrifugal turntable 4, and the pressure sleeve 16 can slide along the outside of the centrifugal turntable 4.

[0037] Specifically, the flexible airbag 14 can be squeezed by the upper push sleeve 16, which makes it easier for the staff to squeeze the flexible airbag 14.

[0038] See Figure 2 The end of the push rod 13 away from the piston plate 12 is connected to a rubber column, and the outer diameter of the rubber column is the same as the outer diameter of the push rod 13.

[0039] Specifically, the rubber column prevents the push rod 13 from making hard contact with the test tube, thus providing a certain degree of protection.

[0040] See Figure 1 It also includes a base 1, which has an internal mounting cavity, and the centrifugal motor 2 is fixedly installed inside the mounting cavity.

[0041] Specifically, by setting the base 1, the contact area between the device and the worktable is increased, which can improve its stability during the centrifugation process.

[0042] See Figure 2 Multiple centrifuge tanks 5 are arranged in a circular array on the centrifuge turntable 4, and each centrifuge tank 5 is inclined. The top surface of the base 1 is formed with a frustum groove that communicates with the centrifuge tank 5. The top surface of the centrifuge turntable 4 is covered with a sealing cover 6, and the bottom surface of the sealing cover 6 is provided with a flexible silicone plug 8 that can be inserted into the frustum groove.

[0043] Specifically, the flexible silicone plug 8 can improve the stability of the test tubes placed inside the centrifuge tank 5.

[0044] See Figure 2 The top surface of the sealing cover 6 is provided with a knob 7, the bottom surface of the sealing cover 6 is provided with a limit ring 9, the top surface of the centrifugal turntable 4 is provided with a limit groove 10, and the limit ring 9 is threadedly connected to the inside of the limit groove 10.

[0045] Specifically, the knob 7 makes it easy to lift the sealing cover 6 and place it on the centrifugal turntable 4. The combination of the limiting ring 9 and the limiting groove 10 can fix the sealing cover 6 on the centrifugal turntable 4, preventing the sealing cover 6 from falling off the centrifugal turntable 4 during centrifugation.

[0046] As described above, although the present invention has been shown and described with reference to specific preferred embodiments, it should not be construed as limiting the present invention itself. Various changes in form and detail may be made to the present invention without departing from the spirit and scope of the appended claims.

Claims

1. A formulation device for apolipoprotein B, characterized in that: include Centrifugal motor (2), with a drive shaft (3) extending vertically upward connected to its drive end, a centrifugal turntable (4) connected to the drive shaft (3), and a plurality of centrifugal grooves (5) for placing test tubes opened on the centrifugal turntable (4); The number of sealed cavities (11) is the same as that of centrifuge tanks (5), and one end of the cavity is connected to the inside of the centrifuge tank (5). A piston plate (12) is slidably installed inside the cavity, and a push rod (13) that can extend into the centrifuge tank (5) is connected to the piston plate (12). An air supply component is installed on the centrifugal turntable (4) to supply air into the sealed cavity (11) to drive the piston plate (12) to push the push rod (13) to slide into the centrifugal tank (5).

2. The formulation device for apolipoprotein B as described in claim 1, characterized in that: The gas supply component includes A flexible airbag (14) is attached to the outer wall of the centrifugal turntable (4); An airflow channel (15) is opened inside the centrifugal turntable (4), with one end connected to the piston plate (12) and the other end connected to the flexible airbag (14).

3. A formulation device for apolipoprotein B as described in claim 2, characterized in that: The centrifugal turntable (4) is fitted with a pressure sleeve (16), which can slide along the outside of the centrifugal turntable (4).

4. A formulation device for apolipoprotein B as described in claim 1, characterized in that: The push rod (13) is connected to a rubber column at the end away from the piston plate (12), and the outer diameter of the rubber column is the same as the outer diameter of the push rod (13).

5. A formulation device for apolipoprotein B as described in claim 1, characterized in that: It also includes a base (1), the base (1) having an installation cavity inside, and the centrifugal motor (2) being fixedly installed inside the installation cavity.

6. A formulation device for apolipoprotein B as described in claim 5, characterized in that: Multiple centrifugal tanks (5) are arranged in a circular array on a centrifugal turntable (4), and each centrifugal tank (5) is inclined. The top surface of the base (1) is formed with a frustum groove that communicates with the centrifugal tank (5).

7. A formulation device for apolipoprotein B as described in claim 6, characterized in that: The top surface of the centrifugal turntable (4) is covered with a sealing cap (6), and the bottom surface of the sealing cap (6) is provided with a flexible silicone plug (8) that can be inserted into the frustum groove.

8. A formulation device for apolipoprotein B as described in claim 7, characterized in that: The top surface of the sealing cover (6) is provided with a knob (7), the bottom surface of the sealing cover (6) is provided with a limiting ring (9), the top surface of the centrifugal turntable (4) is provided with a limiting groove (10), and the limiting ring (9) is threaded into the inside of the limiting groove (10).

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