GEn nuclease reagent heat preservation device

Abstract

The utility model discloses a GEn nuclease reagent heat preservation device which comprises a heat preservation box, a concentric-square-shaped medium cavity formed in the top of the heat preservation box and used for adding a cooling medium to ensure low-temperature keeping, and a plurality of reagent frames fixed to the inner side of the heat preservation box. A plurality of placing cylinders are fixed on the reagent shelf; a coaxial clamping mechanism is arranged at the top of the placing barrel and comprises a plurality of clamping pieces hinged to the top end of the placing barrel; through cooperation of a power source, a moving ring, a connecting strip, a clamping piece, an arc-shaped clamping strip and a reset spring, a placement gap can be prevented from being generated in the reagent tube and the placement barrel, the opening and closing degree of the clamping piece can be flexibly adjusted according to the diameter of the reagent tube, tight fixation of the reagent tube is achieved, stable clamping of the reagent tube can be ensured, and the reagent tube placement device is convenient to use. The reagent tube is effectively prevented from falling off and being damaged, so that the condition that the reagent tube is damaged, leaked or collided with one another due to the fact that the reagent tube is separated from the placing barrel due to repeated shaking is avoided.

Description

TECHNICAL FIELD

[0001] The utility model relates to nuclease technical field especially relates to a GEn nuclease reagent heat preservation device. BACKGROUND

[0002] In the field of biological experiments and molecular biology research, the preservation and transportation of nucleases is a crucial link. Nucleases, as a class of enzymes that can cut DNA or RNA chains, are highly dependent on storage conditions. During transportation, a heat preservation device is needed to store and transport nuclease reagents.

[0003] The utility model discloses a kind of separated heat preservation kits, including box, and the box cover connected with box, box includes upper box and lower box, upper box includes at least two sub-boxes, inner liner is equipped in sub-box, sub-box is connected with lower box by connecting piece respectively, the both ends of connecting piece are rotatably connected with sub-box, lower box, buckle is equipped at the opening and closing of the three side walls of box and box cover;Inner liner includes fixed inner liner for holding fixed reagent tube and dropper, fixed inner liner includes fixed box, first fixed cylinder for accommodating reagent tube is equipped on fixed box, elastic fixing structure is equipped in first fixed cylinder, and second fixed cylinder for fixing dropper. The kit is simple in structure, which is convenient to maintain the temperature environment in the kit, ensures the activity and use effect of the reagent, can be divided in the kit, can create different temperature environment conditions at the same time, can save multiple different reagents at the same time, is convenient to use and operate, and reduces the waste of the kit.

[0004] Although the device can provide the temperature environment of reagent and stable placement, the device only uses the deformation amount of elastic fixing structure itself to realize the clamping of reagent tube, and when carrying the heat preservation kit for transfer, jolt, collision or repeated shaking by external force is inevitable, and reagent tube is easy to be separated from elastic fixing structure due to elastic deformation, so that reagent tube is easy to be damaged, leaked or collided. SUMMARY

[0005] The utility model overcomes the insufficient of prior art, provides a kind of GEn nuclease reagent heat preservation device.

[0006] To achieve the above object, the utility model adopts the technical scheme of: a kind of GEn nuclease reagent heat preservation device, comprising: heat preservation box, backshaped medium cavity for adding cooling medium to ensure low temperature is kept being arranged in the top of the heat preservation box, and a plurality of reagent racks are fixed in the inner side of the heat preservation box;A plurality of placing cylinders are fixed on the reagent rack;

[0007] The top of the placing cylinder is provided with a coaxial clamping mechanism, which comprises a plurality of clamping pieces hinged at the top end of the placing cylinder, a moving ring slidingly connected to the side surface of the placing cylinder, and a plurality of connecting strips arranged between the moving ring and the side surface of the plurality of clamping pieces.

[0008] The middle part of the reagent rack is provided with a power source for driving the plurality of moving rings to slide synchronously, and the inner side of the placing cylinder is provided with a plurality of arc-shaped clamping strips, and a reset spring is fixed between one side of the arc-shaped clamping strips and the inner side of the placing cylinder.

[0009] In a preferred embodiment of the utility model, the plurality of clamping pieces and the plurality of arc-shaped clamping strips are uniformly distributed in the circumferential direction, one end of the connecting strip is hinged to one side of the clamping piece, and the other side is hinged to the side surface of the moving ring.

[0010] In a preferred embodiment of the utility model, the cooling medium is one of ice blocks, ice water or cooling liquid.

[0011] In a preferred embodiment of the utility model, the power source comprises an electric telescopic rod arranged between adjacent placing cylinders and a connecting frame fixed to the output end of the electric telescopic rod; the bottom of the electric telescopic rod is fixed to the inner bottom of the heat preservation box, and the side surface of the connecting frame is fixed to the side surface of the plurality of moving rings.

[0012] In a preferred embodiment of the utility model, one side of the clamping piece towards the middle part of the placing cylinder is provided with anti-skid lines.

[0013] In a preferred embodiment of the utility model, one side of the arc-shaped clamping strip towards the middle part of the placing cylinder is provided with an anti-skid pad.

[0014] In a preferred embodiment of the utility model, the top of the heat preservation box is provided with a box cover, and the top of the box body is fixedly provided with a handle; one side of the box cover is hinged to the back surface of the heat preservation box, and the other side is clamped to the front surface of the heat preservation box.

[0015] In a preferred embodiment of the utility model, the bottom of the box cover is fixedly provided with a back-shaped block, the back-shaped block is clamped to the top of the back-shaped medium cavity, and the contact surfaces of the two are provided with sealing strips.

[0016] In a preferred embodiment of the utility model, the front surface of the heat preservation box is fixedly provided with a label box for placing labels.

[0017] In a preferred embodiment of the utility model, the bottom of the heat preservation box is fixedly provided with anti-skid supporting feet for improving the stability of the heat preservation box when placed.

[0018] The utility model solves the defects in the background art, and has the following beneficial effects:

[0019] (1) The utility model provides a kind of GEn nucleic acid enzyme reagent incubation device, by setting coaxial clamping mechanism in the top of placing cylinder, cooling medium that keeps low-temperature environment in incubator is added to backshaped medium cavity, and after multiple reagents are placed in several placing cylinders on several reagent racks, the cooperation of power source, moving ring, connecting strip, clamping piece, arc clamping strip and return spring can avoid the internal placement gap of reagent tube and placing cylinder, and the opening degree of clamping piece can be flexibly adjusted according to the diameter size of reagent tube, the tight fixing of reagent tube is realized, the stable clamping of reagent tube can be ensured, the falling and breakage of reagent tube are effectively prevented, so as to avoid the breakage, leakage or mutual impact of reagent tube due to repeated shaking from placing cylinder.

[0020] (2) In the utility model, by setting anti-skid line on the side of clamping piece, and setting anti-skid pad on the side of arc clamping strip, the friction between clamping piece and arc clamping strip and reagent tube can be further enhanced, even in the process of transportation, the sliding and mutual impact of reagent tube can be effectively prevented, reagent tube is prevented from sliding or loosening in clamping process, the integrity of reagent tube is protected, and the safe storage of reagent is ensured.

[0021] (3) In the utility model, by fixing backshaped block on the bottom of box cover, when box cover closes the top of incubator, backshaped block is clamped on the top of backshaped medium cavity, and sealing strip is arranged on the contact surface of the two, the incubator can be closed in the state of box cover, and backshaped medium cavity has good sealing property, so that cooling medium can be prevented from overflowing from backshaped medium cavity. BRIEF DESCRIPTION OF DRAWINGS

[0022] The utility model is further illustrated below in connection with drawings and examples;

[0023] Figure 1 It is the perspective structural drawing of preferred embodiment of the utility model;

[0024] Figure 2 It is the box cover opening structure drawing of preferred embodiment of the utility model;

[0025] Figure 3 It is the connecting frame and moving ring connection structure and its local enlarged view of preferred embodiment of the utility model;

[0026] Figure 4 It is the placing cylinder overhead structure drawing of preferred embodiment of the utility model;

[0027] In the figure: 1, incubator; 11, back-shaped medium cavity; 2, reagent rack; 21, placing cylinder; 3, clamping piece; 31, moving ring; 32, connecting strip; 33, arc-shaped clamping strip; 34, reset spring; 4, electric telescopic rod; 41, connecting frame; 5, box cover; 51, handle; 6, back-shaped block; 7, label box; 8, anti-skid supporting leg. DETAILED DESCRIPTION

[0028] The utility model will be explained in further detail in combination with the drawings and embodiments, these drawings are all simplified schematic diagram, only with schematic way illustrates the basic structure of the utility model, therefore it only shows the constitution related to the utility model.

[0029] As Figures 1-4 shown, a GEn nuclease reagent incubation device, including: incubator 1, open in the top of incubator 1 for adding cooling medium to ensure low temperature keeps back-shaped medium cavity 11, and fixed in the inside of incubator 1 several reagent racks 2, reagent rack 2 is fixed with several placing cylinders 21, the top of placing cylinder 21 is provided with coaxial clamping mechanism, coaxial clamping mechanism includes: several clamping pieces 3 that are hinged in the top end of placing cylinder 21, moving ring 31 that is slidingly connected in the side of placing cylinder 21, and several connecting strips 32 that are arranged in the side of moving ring 31 and several clamping pieces 3, reagent rack 2 middle part is provided with power source for driving several moving rings 31 synchronous sliding, the inside of placing cylinder 21 is provided with several arc-shaped clamping strips 33, and reset spring 34 is fixed between the inside of placing cylinder 21 and the side of arc-shaped clamping strip 33.

[0030] Need to explain, several clamping pieces 3 and several arc-shaped clamping strips 33 are evenly distributed in circumference, one end of connecting strip 32 is hinged with one side of clamping piece 3, and the other side is hinged with the side of moving ring 31, cooling medium is one of ice block, ice water or coolant, the cooling medium that keeps the low temperature environment in incubator 1 is added to back-shaped medium cavity 11, and multiple reagents are placed in several placing cylinders 21 on several reagent racks 2, by the floatable clamping force of arc-shaped clamping plate and reset spring 34, it clamps the side of reagent tube located inside placing cylinder 21, avoids the placement gap between reagent tube and the inside of placing cylinder 21, simultaneously utilizes power source to drive several moving rings 31 synchronous sliding to the top end of placing cylinder 21, by several connecting strips 32 that are hinged between moving ring 31 and several clamping pieces 3, can make several clamping pieces 3 on the top end of each placing cylinder 21 coaxial close, can flexibly adjust the opening degree of clamping piece 3 according to the diameter size of reagent tube, realizes the close fixing of reagent tube, can ensure the firm clamping of reagent tube, effectively prevents the falling and breakage of reagent tube, thereby avoids the breakage, leakage or mutual impact of reagent tube due to repeated shaking and separating from placing cylinder 21.

[0031] As Figure 2 and Figure 3As shown, in some embodiments, the power source includes: an electric telescopic rod 4 disposed between adjacent placement cylinders 21, and a connecting frame 41 fixed to the output end of the electric telescopic rod 4; the bottom of the electric telescopic rod 4 is fixed to the inner bottom of the insulation box 1, and the side of the connecting frame 41 is fixed to the side of a plurality of movable rings 31.

[0032] It should be noted that the electric telescopic rod 4, through the telescopic movement of its output end, uses the driving force of the electric telescopic rod 4 to drive the connecting frame 41 and the multiple moving rings 31 fixed thereto to slide synchronously, thereby realizing the rapid and accurate adjustment of several clamping pieces 3, improving the convenience and efficiency of operation.

[0033] In some embodiments, the clamping piece 3 is provided with anti-slip texture on the side facing the middle of the placement cylinder 21; the arc-shaped clamping strip 33 is provided with anti-slip pad on the side facing the middle of the placement cylinder 21. The anti-slip texture and anti-slip pad can further enhance the friction between the clamping piece 3 and the arc-shaped clamping strip 33 and the reagent tube. Even if bumps are encountered during transportation, the reagent tube can be effectively prevented from sliding and colliding with each other, preventing the reagent tube from slipping or loosening during clamping, protecting the integrity of the reagent tube, and ensuring the safe storage of the reagent.

[0034] like Figure 1 and Figure 2 As shown, in some embodiments, the top of the insulated box 1 is provided with a lid 5, and the top of the box body is fixed with a handle 51; one side of the lid 5 is hinged to the back of the insulated box 1, and the other side is snapped to the front of the insulated box 1; the lid 5 and the insulated box 1 are connected by hinge and snap-fit, which facilitates opening and closing, and the handle 51 makes it easy for users to hold and lift the whole box, improving the portability of the insulated box 1 when moving.

[0035] In some embodiments, a U-shaped block 6 is fixed to the bottom of the box cover 5. The U-shaped block 6 is snapped onto the top of the U-shaped medium cavity 11, and a sealing strip is provided on the contact surface between the two. By snapping the U-shaped block 6 onto the top of the U-shaped medium cavity 11 and providing a sealing strip on the contact surface between the two, it can be ensured that the box cover 5 has good sealing performance over the U-shaped medium cavity 11 when the heat preservation box 1 is closed, thereby preventing the cooling medium from overflowing from the U-shaped medium cavity 11.

[0036] In some embodiments, a label box 7 for placing labels is fixed to the front of the insulated box 1; the label box 7 facilitates the identification of reagent information and improves the standardization and accuracy of reagent management.

[0037] In some embodiments, the bottom of the insulated box 1 is fixed with anti-slip support feet 8 to improve the stability of the insulated box 1 when it is placed; by setting the anti-slip support feet 8, the friction between the insulated box 1 and the placement surface can be increased, preventing the insulated box 1 from sliding or tipping over due to external forces during placement, thus ensuring the safe storage of reagents.

[0038] The utility model discloses use, add cooling medium (such as ice block, ice water or coolant) to the back -shaped medium cavity 11 in the top of the heat preservation box 1, to maintain the low temperature environment required by reagent storage in the heat preservation box 1. Subsequently, a plurality of reagent tubes are placed in the placing cylinder 21 on each reagent frame 2 in the heat preservation box 1, and the arc-shaped clamping strip 33 on the inner side of the placing cylinder 21 exerts a floating clamping force on the reagent tube under the action of the return spring 34, avoiding the generation of a placing gap. Then, the connecting frame 41 and the plurality of moving rings 31 fixedly connected thereto are driven by the electric telescopic rod 4 to slide synchronously toward the top end of the placing cylinder 21. The sliding of the moving ring 31 drives the coaxial approach of each clamping piece 3, and the opening and closing degree of the clamping piece 3 is flexibly adjusted according to the diameter of the reagent tube, so that the reagent tube is tightly fixed. The anti-slip pattern on the clamping piece 3 and the anti-slip pad on the arc-shaped clamping strip 33 further enhance the friction between the reagent tube and the arc-shaped clamping strip 33, effectively preventing the reagent tube from sliding, colliding or falling off during transportation. In addition, the box cover 5 at the top of the heat preservation box 1 is connected with the main body of the heat preservation box 1 in a hinged and clamped manner, facilitating opening and closing, and the back-shaped block 6 at the bottom of the box cover 5 is clamped at the top of the back-shaped medium cavity 11, cooperating with the sealing strip to ensure the good sealing performance of the heat preservation box 1 in the closed state, preventing the cooling medium from overflowing. The whole device is reasonably designed and convenient to operate, effectively guaranteeing the low-temperature stability and safety of the GEn nuclease reagent during storage and transportation.

[0039] The above is according to the ideal embodiment of the utility model for the enlightenment, through the above-mentioned description, for the person skilled in the art, obviously, the utility model is not limited to the details of the above-mentioned exemplary embodiments, and can realize the utility model in other specific forms without departing from the spirit or basic characteristics of the utility model. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting, and the scope of the utility model is defined by the appended claims rather than the above description, and therefore all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the utility model. Any reference signs in the claims should not be regarded as limiting the claims involved.

[0040] In addition, it should be understood that, although the present specification is described in terms of embodiments, not every embodiment contains only one independent technical solution, and the description of the specification is only for the sake of clarity, and those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can be appropriately combined to form other embodiments that those skilled in the art can understand.

Claims

1. A GEn nuclease reagent incubation device, comprising: Include: The heat preservation box (1) is provided with a back-shaped medium cavity (11) opened at the top of the heat preservation box (1) for adding cooling medium to ensure low temperature preservation, and a plurality of reagent shelves (2) fixed inside the heat preservation box (1); a plurality of placement barrels (21) are fixed on the reagent shelf (2); The top of the placement barrel (21) is provided with a coaxial clamping mechanism, which comprises: a plurality of clamping pieces (3) hinged at the top end of the placement barrel (21), a moving ring (31) slidingly connected to the side of the placement barrel (21), and a plurality of connecting strips (32) arranged between the moving ring (31) and the side of the plurality of clamping pieces (3); The middle of the reagent shelf (2) is provided with a power source for driving a plurality of moving rings (31) to slide synchronously, and the inner side of the placement barrel (21) is provided with a plurality of arc-shaped clamping strips (33), one side of the arc-shaped clamping strip (33) and the inner side of the placement barrel (21) are fixed with a reset spring (34).

2. The GEn nuclease reagent incubation device of claim 1, wherein: A plurality of clamping pieces (3) and a plurality of arc-shaped clamping strips (33) are uniformly distributed in the circumferential direction, one end of the connecting strip (32) is hinged to one side of the clamping piece (3), and the other side is hinged to the side of the moving ring (31).

3. The GEn nuclease reagent incubation device of claim 1, wherein: The cooling medium is one of ice, ice water or coolant.

4. The GEn nuclease reagent incubation device of claim 1, wherein: The power source includes: an electric telescopic rod (4) arranged between adjacent placement barrels (21), and a connecting frame (41) fixed to the output end of the electric telescopic rod (4); the bottom of the electric telescopic rod (4) is fixed to the inner bottom of the heat preservation box (1), and the side of the connecting frame (41) is fixed to the side of a plurality of moving rings (31).

5. The GEn nuclease reagent incubation device of claim 1, wherein: The side of the clamping piece (3) towards the middle of the placement barrel (21) is provided with anti-skid lines.

6. The GEn nuclease reagent incubation device of claim 1, wherein: The side of the arc-shaped clamping strip (33) towards the middle of the placement barrel (21) is provided with an anti-skid pad.

7. The GEn nuclease reagent incubation device of claim 1, wherein: The top of the heat preservation box (1) is provided with a box cover (5), and the top of the box cover is fixed with a handle (51); one side of the box cover (5) is hinged to the back of the heat preservation box (1), and the other side is clamped to the front of the heat preservation box (1).

8. The GEn nuclease reagent incubation device of claim 7, wherein: The bottom of the box cover (5) is fixed with a back-shaped block (6), which is clamped to the top of the back-shaped medium cavity (11), and the contact surfaces of the two are provided with sealing strips.

9. The GEn nuclease reagent incubation device of claim 1, wherein: The front of the heat preservation box (1) is fixed with a label box (7) for placing labels.

10. The GEn nuclease reagent incubation device of claim 1, wherein: The bottom of the heat preservation box (1) is fixed with anti-skid supporting legs (8) for improving the stability of the heat preservation box (1) when placed.

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