Isolation brush for separating semen solids in assisted reproduction technology

Abstract

The utility model discloses an isolation brush for separating seminal fluid solids in an assisted reproduction technology, which belongs to the technical field of seminal fluid processing tools and comprises a brush body, a left sliding plate and a right sliding plate, the left sliding plate and the right sliding plate are in sliding connection with each other, and comb teeth are fixedly connected to the bottoms of the left sliding plate and the right sliding plate. The ends, away from each other, of the left sliding plate and the right sliding plate are connected with handheld rods. At least two rows of comb teeth are arranged in parallel, and every two adjacent rows of comb teeth are fixedly connected to the bottom of the brush body in a staggered mode. The top of the handheld rod is fixedly connected with a clamping mechanism used for clamping a semen cup. According to the utility model, a fence-shaped obstacle is formed by a plurality of rows of staggered comb tooth structures, so that solid matters and floccules in semen can be accurately intercepted and effectively prevented from entering a centrifugal tube, the gradient centrifugal effect is protected, and the recovery rate of high-quality sperms is improved; the handheld rod is arranged, so that fixing and using are facilitated, the semen treatment process is simplified, operation errors are reduced, and the semen treatment efficiency and success rate in the assisted reproduction technology are remarkably improved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to semen processing tool technical field, especially relate to a separation brush for separating semen solid in assisted reproductive technology. BACKGROUND

[0002] Semen processing is one of the key steps in assisted reproductive technology (ART), and its purpose is to separate high-quality sperm with good activity for further in vitro fertilization or microinjection operation. In the current experiment and clinical practice, gradient centrifugation method is the main method of semen separation. However, due to incomplete liquefaction of semen of some patients, undegraded gelatinous solid or flocculent material may remain in the liquefied semen. These solids can significantly affect the layering effect and sperm recovery rate of subsequent gradient centrifugation.

[0003] Chinese patent with publication number CN204219887U discloses a special mesh screen for density gradient centrifugation of liquefied abnormal semen. The upper part of the mesh screen is a filter part in a cylindrical structure, and a filter screen is arranged inside the filter part. The filter screen is composed of two identical filter plates stacked on each other, and the relative position between the two filter plates is adjusted by a pore size adjusting knob arranged outside the filter part. The lower part of the mesh screen is a drainage part, and the upper end of the drainage part is connected with the bottom of the filter part. The opening of the lower end of the drainage part gradually narrows to one side and forms a drainage port at the bottom. A drainage tube is connected below the drainage port. However, this special mesh screen for density gradient centrifugation of liquefied abnormal semen has deficiencies in structure design, semen processing effect, and operation convenience. First, the structure may cause physical damage to sperm by gravity screening, thereby affecting the activity and function of sperm. Second, the use of multiple layers of filter membranes may cause loss of part of the sperm during the filtering process, and the sperm concentration is low, which may affect the subsequent application effect. In addition, the screening and separation process of this method takes a long time, which may reduce the processing efficiency of the system, especially when processing a large number of samples.

[0004] Therefore, a separation brush for separating semen solid in assisted reproductive technology is proposed. UTILITY MODEL CONTENT

[0005] To solve the above technical problems, the utility model provides a separation brush for separating semen solid in assisted reproductive technology.

[0006] To achieve the above purpose, the utility model provides a separation brush for separating semen solid in assisted reproductive technology, which comprises:

[0007] The brush body comprises a left sliding plate and a right sliding plate which are slidably connected to each other, and the bottom of each of the left sliding plate and the right sliding plate is fixedly connected with a comb tooth, and the end of each of the left sliding plate and the right sliding plate away from each other is connected with a hand holding rod.

[0008] The comb teeth are arranged in at least two rows in parallel, and the comb teeth of adjacent two rows are fixedly connected to the bottom of the brush body in an interlaced manner.

[0009] The hand holding rod is vertically connected with the left sliding plate and the right sliding plate, and the top of the hand holding rod is fixedly connected with a clamping mechanism for clamping a precision cup.

[0010] According to the isolation brush for separating sperm solid substances in the assisted reproductive technology provided by the application, the left and right interval of the comb teeth is ±0.3 mm, and the row interval is ±0.3 mm.

[0011] According to the isolation brush for separating sperm solid substances in the assisted reproductive technology provided by the application, the side face of each of the left sliding plate and the right sliding plate close to each other is provided with a sliding groove, and the side face of each of the left sliding plate and the right sliding plate is fixedly connected with a sliding block corresponding to the sliding groove, and the sliding block is fixedly connected to the end side face of the left sliding plate or the right sliding plate close to each other.

[0012] According to the isolation brush for separating sperm solid substances in the assisted reproductive technology provided by the application, the clamping mechanism is a spring clamp, the spring clamp comprises a long clamping plate and a short clamping plate, the long clamping plate and the short clamping plate are hingedly connected through a spring, the outer side of the long clamping plate is fixedly connected with the top of the hand holding rod, and the clamping end of the long clamping plate abuts against the outer side of the hand holding rod.

[0013] According to the isolation brush for separating sperm solid substances in the assisted reproductive technology provided by the application, the hand holding rod is detachably connected to the top face of the brush body.

[0014] According to the isolation brush for separating sperm solid substances in the assisted reproductive technology provided by the application, the hand holding rod is rotatably connected to the top face of the brush body, so that the hand holding rod is folded and placed on the top face of the brush body.

[0015] Compared with the prior art, the isolation brush has the following advantages and technical effects:

[0016] The three rows of comb teeth are fixedly connected in a staggered manner to the bottom of the brush body in a multi-layer fence structure. In use, the multi-layer fence structure of the comb teeth part separates the semen into solid and liquid. When the semen passes through the comb teeth, the solid and flocculent substances that have not been liquefied are effectively intercepted by the comb teeth and are retained on the surface of the brush body. The liquid semen and the sperm suspended therein can flow into the bottom of the container through the pores between the comb teeth. The separated semen liquid enters the centrifugal tube for subsequent gradient centrifugation operation. The multi-row staggered design of the comb teeth avoids the problem that the single-layer comb teeth cannot intercept small solid substances, reduces the blocking phenomenon, ensures the fluidity of the liquid, accurately intercepts the solid and flocculent substances in the semen, effectively prevents the solid and flocculent substances from entering the centrifugal tube, protects the gradient centrifugation effect, and improves the recovery rate of high-quality sperm. The hand-held rod is pulled and moved, and the clamping mechanism is clamped on the top of the semen cup to facilitate fixing and use, simplify the semen processing process, reduce operation errors, and significantly improve the efficiency and success rate of semen processing in assisted reproductive technology. BRIEF DESCRIPTION OF DRAWINGS

[0017] The accompanying drawings, which form a part of this application, are included to provide a further understanding of the application and are incorporated in and constitute a part of this application. The embodiments of the present application illustrated in the drawings and their descriptions are used to explain the present application and are not intended to limit the present application. In the drawings:

[0018] Fig. 1 It is a schematic diagram of the isolation brush structure for separating semen solid in the assisted reproductive technology of the present application.

[0019] Fig. 2 It is a schematic diagram of the internal structure of the brush body in the present application.

[0020] Fig. 3 It is a bottom view of the isolation brush for separating semen solid in the assisted reproductive technology of the present application. In the figure: 1, brush body; 2, comb teeth; 3, hand-held rod; 4, spring clamp; 101, left sliding plate; 102, right sliding plate; 103, sliding groove; 104, sliding block; 401, long clamping plate; 402, short clamping plate. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0022] In order to make the above-mentioned purposes, characteristics and advantages of the present application more obvious and easy to understand, the present application will be further described in detail below with reference to the drawings and specific embodiments.

[0023] Embodiment 1

[0024] Referring to Figs. 1 to 3 As shown in the drawings, the present embodiment provides an isolation brush for separating sperm solid in assisted reproductive technology, comprising:

[0025] The brush body 1 comprises a left sliding plate 101 and a right sliding plate 102, which are connected to each other in sliding mode, and the bottom of each of the left sliding plate 101 and the right sliding plate 102 is fixedly connected with a comb tooth 2, and the end of each of the left sliding plate 101 and the right sliding plate 102 away from each other is connected with a hand-held rod 3;

[0026] The comb teeth 2 are arranged in parallel in at least two rows, and the adjacent two rows of comb teeth 2 are fixedly connected to the bottom of the brush body 1 in staggered mode;

[0027] The hand-held rod 3 is connected perpendicularly to the left sliding plate 101 and the right sliding plate 102, and a clamping mechanism is fixedly connected to the top of the hand-held rod 3 for clamping a sperm cup.

[0028] The comb teeth 2 are arranged in parallel in three rows and fixedly connected to the bottom of the brush body 1 in a multi-layer fence structure, and in the use process of the present application, the multi-layer fence structure of the comb teeth 2 separates the solid and liquid: when the sperm passes through the comb teeth 2, the un-liquefied solid and flocculent are effectively intercepted by the comb teeth 2 and retained on the surface of the brush body 1. The liquid sperm and the sperm suspended therein can flow smoothly through the pores between the comb teeth 2 into the bottom of the container. The separated sperm liquid enters the centrifugal tube for subsequent gradient centrifugation operation. The multi-row staggered design of the comb teeth 2 avoids the problem that the single-layer comb teeth 2 cannot intercept small solid, reduces the blocking phenomenon, ensures the fluidity of the liquid, accurately intercepts the solid and flocculent in the sperm, effectively avoids the solid and flocculent from entering the centrifugal tube, protects the gradient centrifugation effect, and improves the recovery rate of high-quality sperm. The hand-held rod 3 is pulled and moved, and the clamping mechanism is clamped on the top of the sperm cup to facilitate fixation and use, simplify the sperm processing process, reduce operation errors, and significantly improve the efficiency and success rate of sperm processing in assisted reproductive technology.

[0029] In addition, by pulling the hand-held rod 3 in reverse, the left sliding plate 101 and the right sliding plate 102 can slide in reverse, the overlapping part of the left sliding plate 101 and the right sliding plate 102 can be shortened, and thus the length of the brush body 1 as a whole can be changed to adapt to the size of different sperm cups, so that the comb teeth 2 at the bottom of the brush body 1 can have the same cross-sectional width as the corresponding section of the sperm cup, and the comb teeth 2 will not be too short to have a gap with the edge of the sperm cup, so that the gelatinous solid or flocculent in the sperm that needs to be intercepted can flow out from the gap.

[0030] Further, the present application is made of medical-grade polystyrene material, sterilized by gamma rays and packaged aseptically, and is disposable to avoid cross-contamination, high safety and meet the clinical operation standards of assisted reproductive technology.

[0031] The embodiment provides an isolation brush for separating seminal solid in assisted reproductive technology, the left-right interval of the comb tooth 2 is 1+ / -0.3 mm, and the row interval is 1+ / -0.3 mm.

[0032] The left-right interval of the comb tooth 2 and the front-back row interval are precisely designed, so that the effective interception of the solid is ensured, and the obstruction of liquid flow is avoided, thereby optimizing the seminal separation process and ensuring the efficient separation of liquid semen and sperm recovery.

[0033] The embodiment provides an isolation brush for separating seminal solid in assisted reproductive technology, the left side of the left sliding plate 101 and the right sliding plate 102 close to each other is provided with a sliding groove 103, the left side of the left sliding plate 101 and the right sliding plate 102 is fixedly connected with a sliding block 104 corresponding to the sliding groove 103, and the sliding block 104 is fixed to the end side of the left sliding plate 1 or the right sliding plate 102 close to each other after sliding.

[0034] According to the isolation brush for separating seminal solid in assisted reproductive technology provided by the application, the sliding groove 103 is a T-shaped groove, and the sliding block 104 is a T-shaped block; the T-shaped sliding groove 103 and the sliding block 104 are convenient for left-right sliding and are not easy to slide off.

[0035] The left sliding plate 101 and the right sliding plate 102 are translated relative to each other by sliding in the sliding groove 103, so that the width of the brush body 1 is changed.

[0036] The embodiment provides an isolation brush for separating seminal solid in assisted reproductive technology, the clamping mechanism is a spring clamp 4, the spring clamp 4 includes a long clamping plate 401 and a short clamping plate 402, the long clamping plate 401 and the short clamping plate 402 are hingedly connected through a spring, the outer side of the long clamping plate 401 is fixedly connected with the top of the handheld rod 3, and the clamping end of the long clamping plate 401 abuts against the outer side of the handheld rod 3.

[0037] The long clamping plate 401 and the handheld rod 3 are in butt joint to realize clamping, the clamping point is located at the bottom end of the handheld rod 3, different height of the sperm cup can be clamped, as long as the comb tooth 2 abuts against the bottom of the sperm cup, and the height of the top surface of the sperm cup is between the bottom end of the long clamping plate 401 and the hinge joint point of the spring clamp 4.

[0038] Embodiment 2

[0039] The isolation brush for separating seminal solid in assisted reproductive technology in the embodiment is different from that in embodiment 1 only in that the handheld rod 3 is detachably connected to the top surface of the brush body 1.

[0040] The handheld rod 3 is detachably connected to the top surface of the brush body 1, so that the isolation brush is convenient to pack, the area of a packaging bag and the transportation volume are reduced, and the cost is reduced.

[0041] Specifically, the bottom of the hand rod 3 is provided with a mounting hole, and the top surface of the brush body 1 is provided with mounting columns at both ends corresponding to the mounting hole, and the hand rod 3 and the brush body 1 are detachably connected by inserting the mounting columns into the mounting hole.

[0042] Embodiment 3

[0043] The isolation brush for separating sperm solid in the assisted reproductive technology of the embodiment is different from that of embodiment 1 only in that the hand rod 3 is rotationally connected to the top surface of the brush body 1, so that the hand rod 3 is folded and placed on the top surface of the brush body 1.

[0044] The hand rod 3 is rotationally connected to the top surface of the brush body 1, so that the hand rod 3 is folded and placed on the top surface of the brush body 1, thereby reducing the packaging area and the transportation volume and reducing the cost.

[0045] Specifically, the connecting structure between the hand rod 3 and the brush body 1 is similar to a disposable folding spoon, and the hand rod 3 can be positionally limited by the fixing column when being upright, and the specific structure is prior art, which will not be described here.

[0046] The details of the utility model not described are conventional technical means known to those skilled in the art.

[0047] In the description of the utility model, it is understood that the orientation or positional relationship indicated by the terms "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like is the orientation or positional relationship shown based on the drawings, and is only for the convenience of describing the utility model, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the utility model.

[0048] The above-described embodiments are only preferred modes for describing the utility model, and do not limit the scope of the utility model, and various modifications and improvements to the technical solutions of the utility model made by those skilled in the art without departing from the design spirit of the utility model should fall within the protection scope of the utility model claim.

Claims

1. An isolation brush for separating seminal solid matter in assisted reproductive technology, characterized in that, Include: Brush body (1), including left slide plate (101) and right slide plate (102), the left slide plate (101) and the right slide plate (102) are slidably connected, the bottom of the left slide plate (101) and the right slide plate (102) is fixedly connected with comb tooth (2), the end of the left slide plate (101) and the right slide plate (102) away from each other is connected with hand-held rod (3) respectively; The comb tooth (2) is provided with at least two rows in parallel, and the adjacent two rows of comb teeth (2) are fixedly connected to the bottom of the brush body (1) in staggered mode; The hand-held rod (3) is connected with the left slide plate (101) and the right slide plate (102) perpendicularly, and the hand-held rod (3) is fixedly connected with clamping mechanism at the top for clamping precision cup.

2. The isolation brush for separating seminal solid from the semen in the assisted reproductive technology according to claim 1, characterized in that: The left slide plate (101) and the right slide plate (102) are connected with the left slide plate (101) and the right slide plate (102) perpendicularly, and the hand-held rod (3) is fixedly connected with clamping mechanism at the top for clamping precision cup.

3. The isolation brush for separating seminal solid from the semen in the assisted reproductive technology according to claim 1, characterized in that: The left slide plate (101) and the right slide plate (102) are connected with the left slide plate (101) and the right slide plate (102) perpendicularly, and the hand-held rod (3) is fixedly connected with clamping mechanism at the top for clamping precision cup.

4. The isolation brush for separating sperm solid from semen in assisted reproductive technology according to claim 1, characterized in that: The left slide plate (101) and the right slide plate (102) are connected with the left slide plate (101) and the right slide plate (102) perpendicularly, and the hand-held rod (3) is fixedly connected with clamping mechanism at the top for clamping precision cup.

5. The isolation brush for separating sperm solid from semen in assisted reproductive technology according to claim 1, characterized in that: The hand-held rod (3) is detachably connected to the top surface of the brush body (1).

6. The isolation brush for separating sperm solid from semen in assisted reproductive technology according to claim 1, characterized in that: The hand-held rod (3) is rotatably connected to the top surface of the brush body (1), so that the hand-held rod (3) is folded and placed on the top surface of the brush body (1).

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