Mesh hydrogel dressing

By designing a mesh hydrogel dressing, utilizing porous three-dimensional hydrogels and zwitterionic polymers, the problem of traditional hydrogel dressings being unable to support cell growth and repair was solved, achieving effective wound healing and exudate absorption, and promoting cell repair and rapid healing of diabetic wounds.

CN223682713UActive Publication Date: 2025-12-19DUXING (SHANDONG) MEDICAL MATERIALS CO LTD
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Patent Information

Application Number
CN202422948817.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-02
Publication Date
2025-12-19
Estimated Expiration
2034-12-02

AI Technical Summary

Technical Problem

Traditional hydrogel dressings cannot support cell growth and repair, resulting in necrotic cell debris remaining in the wound.

Method used

A mesh-like hydrogel dressing was designed, comprising an isolation layer, a three-dimensional layer, a dilution layer, and a protective layer. It utilizes porous three-dimensional hydrogel and zwitterionic polymer to promote the removal of necrotic cell debris, increase the contact area between the wound and the dressing, and absorb exudate through polyvinyl alcohol foam material to support cell growth and repair.

Benefits of technology

It promotes cell growth and repair, reduces the number of cells in the inflammatory phase, increases the number of cells in the proliferative phase, effectively absorbs wound exudate, and promotes wound healing, especially for diabetic wounds.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of medical dressings, and discloses a net-shaped hydrogel dressing which comprises a dressing body, an isolating layer is fixedly connected inside the dressing body, a three-dimensional layer is fixedly connected to the lower layer of the isolating layer, a dilution layer is fixedly connected to the lower layer of the three-dimensional layer, a protective layer is fixedly connected to the lower layer of the dilution layer, and the protective layer is fixedly connected to the lower layer of the protective layer. The dressing body is hydrogel dressing, the hydrogel dressing can be better attached to the irregular shape of a wound, due to the fact that the net-shaped structure of the hydrogel dressing has certain elasticity and flexibility, the hydrogel dressing can deform according to the outline of the wound, external bacteria are prevented from entering the wound through gaps, and meanwhile effective ingredients in hydrogel can better act on the wound. According to the porous three-dimensional hydrogel dressing, the porous three-dimensional hydrogel is additionally arranged in the hydrogel dressing, so that the effects of facilitating transmission of nutrient substances, supporting growth and repair of cells, increasing the contact area between a wound and the dressing and promoting removal of necrotic cell garbage can be achieved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to medical dressing technical field especially relates to a netted hydrogel dressing. BACKGROUND

[0002] Traditional hydrogel dressing is rich in a large amount of moisture, can simulate the moist environment of human tissue, after contacting the wound, can absorb wound exudate and keep certain humidity, avoid the wound dry, simultaneously provide physical barrier for the wound, reduce the invasion of outside pathogenic bacteria.

[0003] Traditional hydrogel dressing, in the process of using, usually adopt three-dimensional network structure, when using, cannot support the growth and repair of cells, lead to necrotic cell garbage to stay in the wound. UTILITY MODEL CONTENT

[0004] In order to make up for above insufficient, the utility model provides a netted hydrogel dressing, aims at improving the problem that traditional hydrogel dressing cannot support the growth and repair of cells, lead to necrotic cell garbage to stay in the wound.

[0005] In order to achieve the above object, the utility model provides the following technical scheme:

[0006] A netted hydrogel dressing, including dressing body, the inside fixedly connected with the isolation layer of dressing body, the lower fixedly connected with the stereoscopic layer of isolation layer, the lower fixedly connected with the dilution layer of stereoscopic layer, the lower fixedly connected with the protective layer of dilution layer, the dressing body is hydrogel dressing, and hydrogel dressing can better fit the irregular shape of wound, because its netted structure has certain elasticity and flexibility, it can be deformed according to the contour of wound, avoids that the bacteria of outside enter the wound through gap, and also can make the effective component in hydrogel better act on the wound.

[0007] Preferably, the isolation layer is release paper, which provides an isolation layer to prevent the hydrogel layer from adhering to other materials, thereby maintaining its integrity and functionality.

[0008] Preferably, the stereoscopic layer is porous stereoscopic hydrogel, which promotes the removal of necrotic cell garbage through its netted structure and increases the contact area of the wound and the dressing.

[0009] Preferably, the dilution layer is polyvinyl alcohol foaming material, which has high hydrophilicity and can effectively absorb wound exudate to ensure reliable removal of wound exudate.

[0010] Preferably, the protective layer is a zwitterionic polymer, which has antibacterial properties and can prevent bacterial and cell adhesion, and synergistically acts with antibacterial agents to further promote wound healing.

[0011] The utility model has the following beneficial effects:

[0012] 1. In the utility model, the porous three-dimensional hydrogel is added in the hydrogel dressing, so that the transmission of nutrients is facilitated, the growth and repair of cells are supported, the contact area of the wound and the dressing is increased, and the effect of removing necrotic cell garbage is promoted.

[0013] 2. In the utility model, the zwitterionic polymer is added on the surface of the hydrogel, so that the number of cells in the inflammatory period is reduced, the number of cells in the proliferation period is increased, the exudate on the wound surface is effectively absorbed, healing is promoted, the immune microenvironment is regulated, and the repair of diabetic wounds is promoted. BRIEF DESCRIPTION OF DRAWINGS

[0014] Fig. 1 A three-dimensional structure schematic diagram of the net-shaped hydrogel dressing is provided for the utility model;

[0015] Fig. 2 An internal structure schematic diagram of the dressing body of the net-shaped hydrogel dressing is provided for the utility model.

[0016] LEGEND:

[0017] 1, dressing body; 2, isolation layer; 3, three-dimensional layer; 4, dilution layer; 5, protective layer. DETAILED DESCRIPTION

[0018] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the specification of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0019] Referring to Figs. 1-2 , the utility model provides an embodiment: a net-shaped hydrogel dressing, including dressing body 1, the inside fixed connection of dressing body 1 has isolation layer 2, the lower layer fixed connection of isolation layer 2 has three-dimensional layer 3, the lower layer fixed connection of three-dimensional layer 3 has dilution layer 4, the lower layer fixed connection of dilution layer 4 has protective layer 5, and the dressing body 1 is hydrogel dressing, and the hydrogel dressing can better fit the irregular shape of the wound. Because the net-shaped structure has a certain elasticity and flexibility, it can deform according to the contour of the wound, avoid bacteria from the outside through the gap into the wound, and also enable the effective components in the hydrogel to better act on the wound. Isolation layer 2 is release paper, and the release paper provides an isolation layer to prevent the hydrogel layer from adhering to other materials, so that the integrity and functionality thereof are maintained.

[0020] Specifically, the specific role of the release paper in protecting the hydrogel layer is to provide an isolation layer to prevent the hydrogel layer from adhering to other materials, thereby maintaining its integrity and functionality. The release paper is usually coated with a release agent such as silicone oil or other release agents to ensure that the hydrogel layer does not stick to the release paper or other surfaces. This isolation function is crucial to the performance of the dressing, as it can prevent the dressing from being contaminated or damaged during use or transportation. However, the release paper needs to be strictly controlled in terms of coating amount and quality during production. If the coating amount of the release paper is uneven, it may result in insufficient release force, making it difficult to peel off the dressing during use, affecting user experience. On the contrary, if the coating amount is too much, it may result in increased cost and too light release force, also affecting the peeling performance of the dressing.

[0021] Referring to Fig. 2 The three-dimensional layer 3 is a porous three-dimensional hydrogel that promotes the removal of necrotic cell debris through its network structure and increases the contact area between the wound and the dressing.

[0022] Specifically, the porous three-dimensional hydrogel (such as carrageenan) serves as a skeleton, and its main purpose is to promote the removal of necrotic cell debris through its network structure and increase the contact area between the wound and the dressing. This design takes advantage of the high water content and good biocompatibility of hydrogels, making them ideal materials for biomimetic extracellular matrix. In addition, the porous structure of hydrogel helps the transfer of nutrients, thereby supporting cell growth and repair.

[0023] Referring to Fig. 2 The dilution layer 4 is a polyvinyl alcohol foam material with high hydrophilicity, which can effectively absorb wound exudate and ensure reliable removal of wound exudate. The protective layer 5 is a zwitterionic polymer with antibacterial properties that can prevent bacterial and cell adhesion, and synergistically promotes wound healing with antibacterial agents.

[0024] Specifically, the application of polyvinyl alcohol foam material in wound dressings has significant advantages. First, polyvinyl alcohol foam material has high hydrophilicity, which can effectively absorb wound exudate and ensure reliable removal of wound exudate. This property enables polyvinyl alcohol-based dressings to maintain wound moisture while promoting toxin removal, thereby accelerating wound healing. In addition, polyvinyl alcohol foam material also has good biocompatibility and biodegradability, and is a non-toxic and non-carcinogenic material. These characteristics make polyvinyl alcohol-based dressings very safe in clinical applications and can be used for various types of wound treatment. Polyvinyl alcohol foam material can also be mixed with other organic and inorganic materials for drug delivery and wound healing. For example, by adding antibiotics such as oxytetracycline, the risk of infection can be reduced and wound healing can be promoted. In addition, polyvinyl alcohol-based dressings can also optimize their performance through physical crosslinking and drug release characteristics to adapt to different treatment needs.

[0025] Working principle: When a mesh hydrogel dressing is needed, place 1 on the patient's wound. The release paper plays a specific role in protecting the hydrogel layer by providing an isolation layer to prevent the hydrogel layer from adhering to other materials, thereby maintaining its integrity and functionality. The release paper is usually coated with a release agent such as silicone oil or other release agents to ensure that the hydrogel layer does not stick to the release paper or other surfaces. This isolation is crucial for the performance of the dressing as it prevents the dressing from being contaminated or damaged before use or during transportation. The zwitterionic polymer has excellent hydrophilicity and anti-protein non-specific adsorption ability, which can interact strongly with water molecules through ionic solvation effect, thereby exhibiting strong surface hydration and anti-fouling performance. The porous three-dimensional hydrogel serves as a scaffold, its main purpose is to promote the removal of necrotic cell debris through its mesh structure and increase the contact area between the wound and the dressing. This design takes advantage of the high water content and good biocompatibility of hydrogels, making them ideal materials for biomimetic extracellular matrix. In addition, the porous structure of hydrogel helps the delivery of nutrients, thereby supporting cell growth and repair. The application of polyvinyl alcohol foam material in wound dressings has significant advantages. First, PVA foam material has high hydrophilicity, which can effectively absorb wound exudate and ensure reliable removal of wound exudate. This property enables PVA-based dressings to maintain wound moisture while promoting toxin removal, thereby accelerating wound healing.

[0026] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and is not intended to limit the present application, although the foregoing embodiments of the present application has been described in detail, for the skilled in the art, it still can be modified, or for part of the technical features of the equivalent replacement, the spirit and principles of the present application, made any modification, equivalent replacement, improvement, etc., should be included within the scope of the present application.

Claims

1. A mesh hydrogel dressing comprising a dressing body (1), characterised in that: The inside of the dressing body (1) is fixedly connected with an isolation layer (2), the lower layer of the isolation layer (2) is fixedly connected with a three-dimensional layer (3), the lower layer of the three-dimensional layer (3) is fixedly connected with a dilution layer (4), the lower layer of the dilution layer (4) is fixedly connected with a protective layer (5), the dressing body (1) is a hydrogel dressing, which can better fit the irregular shape of the wound, because its reticular structure has a certain elasticity and flexibility, it can deform according to the contour of the wound, avoid the entry of external bacteria through the gap into the wound, and also can make the effective components in the hydrogel better act on the wound.

2. A mesh hydrogel dressing according to claim 1, wherein: The isolation layer (2) is release paper, which provides an isolation layer to prevent the hydrogel layer from adhering to other materials, thereby maintaining its integrity and functionality.

3. A mesh hydrogel dressing according to claim 2, wherein: The three-dimensional layer (3) is a porous three-dimensional hydrogel, which promotes the removal of necrotic cell garbage through its reticular structure and increases the contact area of the wound and the dressing.

4. A mesh hydrogel dressing according to claim 3, wherein: The dilution layer (4) is a polyvinyl alcohol foaming material, which has high hydrophilicity and can effectively absorb wound exudate, ensuring reliable removal of wound exudate.

5. A mesh hydrogel dressing according to claim 4, wherein: The protective layer (5) is a zwitterionic polymer, which has antibacterial properties and can prevent bacterial and cell adhesion, and synergistically acts with antibacterial agents to further promote wound healing.