Micro liquid adding device

Abstract

The utility model provides a trace liquid adding device. The trace liquid adding device comprises a solution carrier, a liquid inlet valve, a liquid separation pump, a liquid outlet valve and a liquid separation block, the solution carrier is filled with a target solution; the liquid inlet valve is provided with a first inlet end and a first outlet end, the first inlet end of the liquid inlet valve is communicated with the solution carrier, and the first outlet end of the liquid inlet valve is communicated with the liquid separation pump; the liquid outlet valve is provided with a second inlet end and a second outlet end, the second inlet end of the liquid outlet valve is communicated with the liquid separation pump, and the second outlet end of the liquid outlet valve is communicated with the liquid separation block; the liquid separation block comprises a plurality of liquid separation openings, and each liquid separation opening is provided with an electromagnetic valve; the liquid separation pump is used for driving a target solution contained in the solution carrier to be conveyed to the liquid separation block through the liquid inlet valve, the liquid separation pump and the liquid outlet valve, so that the target solution is separated and output through the multiple electromagnetic valves of the liquid separation block. According to the utility model, the consistency of liquid separation and addition can be improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of liquid addition, in particular to a trace liquid adding device. BACKGROUND

[0002] The traditional chemical synthesis technology often uses compressed nitrogen or argon as power source to add reagent, because the gas itself has compressibility, the control precision is poor, causes the poor consistency of reagent addition, causes the reagent waste, and the synthesis cost is high.

[0003] In addition, in the 1 / 8 liquid path system, 8 PTFE pipelines of 8 needle sleeves are connected to 8 outlets of the strip-shaped liquid distribution block to realize 1 suction and 8 injection batch sample adding, but the pipe resistance of each branch has slight difference, so that the consistency of liquid injection of each branch has technical defects. UTILITY MODEL CONTENT

[0004] The utility model discloses a trace liquid adding device, which can overcome the defects and deficiencies in the prior art.

[0005] One embodiment of the utility model provides a trace liquid adding device, which comprises a solution carrier, a liquid inlet valve, a liquid distribution pump, a liquid outlet valve and a liquid distribution block.

[0006] The solution carrier is provided with a target solution;

[0007] The liquid inlet valve is provided with a first inlet end and a first outlet end, the first inlet end of the liquid inlet valve is communicated with the solution carrier, and the first outlet end of the liquid inlet valve is communicated with the liquid distribution pump;

[0008] The liquid outlet valve is provided with a second inlet end and a second outlet end, the second inlet end of the liquid outlet valve is communicated with the liquid distribution pump, and the second outlet end of the liquid outlet valve is communicated with the liquid distribution block;

[0009] The liquid distribution block comprises a plurality of liquid distribution ports, and each liquid distribution port is provided with an electromagnetic valve;

[0010] The liquid distribution pump is used to drive the target solution in the solution carrier to be transmitted to the liquid distribution block through the liquid inlet valve, the liquid distribution pump and the liquid outlet valve, so that the target solution is distributed and output through the plurality of electromagnetic valves of the liquid distribution block.

[0011] Further, each electromagnetic valve of each liquid distribution port is connected with an infusion needle with the same inner diameter.

[0012] Further, the infusion needle connected with the electromagnetic valve is a steel needle made of stainless steel.

[0013] Further, the liquid inlet valve is a liquid inlet electromagnetic valve, and the liquid outlet valve is a liquid outlet electromagnetic valve. Further, the liquid inlet valve is a liquid inlet electromagnetic valve, and the liquid outlet valve is a liquid outlet electromagnetic valve.

[0014] Further, the liquid distribution pump is a plunger pump, the first outlet end of the liquid inlet valve is communicated with the plunger pump, and the second inlet end of the liquid outlet valve is communicated with the plunger pump.

[0015] Further, the liquid distribution pump is a peristaltic pump, the first outlet end of the liquid inlet valve is communicated with the peristaltic pump, and the second inlet end of the liquid outlet valve is communicated with the peristaltic pump.

[0016] Further, the liquid distribution pump is a constant pump, the first outlet end of the liquid inlet valve is communicated with the constant pump, and the second inlet end of the liquid outlet valve is communicated with the constant pump.

[0017] Further, the liquid distribution pump is a syringe pump, the first outlet end of the liquid inlet valve is communicated with the syringe pump, and the second inlet end of the liquid outlet valve is communicated with the syringe pump.

[0018] Further, the first inlet end of the liquid inlet valve is communicated with the bottom of the solution carrier through a liquid conveying pipe.

[0019] Further, an upper computer is further included, and the upper computer is connected with the liquid inlet valve, the liquid distribution pump, the liquid outlet valve and each electromagnetic valve.

[0020] The upper computer drives the liquid inlet valve to be opened and the liquid outlet valve to be closed, so that the liquid distribution pump sucks the target solution of the solution carrier through the liquid inlet valve.

[0021] The upper computer drives the liquid inlet valve to be closed, the liquid outlet valve to be opened and each electromagnetic valve to be opened, so that the liquid distribution pump outputs the target solution to each electromagnetic valve through the liquid outlet valve, and the target solution is distributed and output through the electromagnetic valves of the liquid distribution block.

[0022] The upper computer drives the electromagnetic valves to be opened in sequence according to a preset sequence and time difference, so that each electromagnetic valve outputs the same amount of target liquid.

[0023] Compared with the prior art, the micro-liquid adding device can add the target solution in the solution carrier through the multiple liquid distribution ports of the liquid distribution block, so that multiple targets can simultaneously obtain the target solution through the corresponding liquid distribution ports, the consistency of liquid distribution and addition is improved, each liquid distribution port is provided with an electromagnetic valve, the amount of liquid output through the corresponding liquid distribution port can be better adjusted by controlling the opening and closing of the electromagnetic valve, and the electromagnetic valve is controlled by the upper computer, so that the upper computer can drive the electromagnetic valves to be opened in sequence according to a preset sequence and time difference, so that each electromagnetic valve outputs the same amount of target liquid, and the consistency of liquid distribution and addition can be more effectively improved.

[0024] In order to more clearly understand the present application, the specific implementation manner of the present application will be described below in combination with the drawings. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of a micro-liquid addition device according to an embodiment of the present invention.

[0026] Figure 2 This is a schematic diagram of the liquid dispensing block of a micro-liquid adding device according to an embodiment of the present invention.

[0027] Figure 3 This is a schematic diagram of the connection of the host computer to the micro-liquid addition device according to an embodiment of the present invention.

[0028] Figure 4 This is a schematic diagram of the motion curve of the separatory pump in a micro-liquid addition device according to an embodiment of the present invention.

[0029] 1. Solution carrier; 2. Inlet valve; 3. Dispensing pump; 4. Outlet valve; 5. Dispensing block; 6. Solenoid valve; 7. Steel needle; 8. Host computer. Detailed Implementation

[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0031] Please see Figure 1 This is a schematic diagram of a micro-liquid addition device according to an embodiment of the present invention, including: a solution carrier 1, an inlet valve 2, a dispensing pump 3, an outlet valve 4, and a dispensing block 5;

[0032] The solution carrier 1 contains the target solution; wherein, the solution carrier 1 can be a reagent bottle, test tube, or other vessel commonly used in the biochemical field to hold solutions.

[0033] The liquid inlet valve 2 is provided with a first inlet end and a first outlet end. The first inlet end of the liquid inlet valve 2 is connected to the solution carrier 1, and the first outlet end of the liquid inlet valve 2 is connected to the liquid separator pump 3.

[0034] The liquid outlet valve 4 is provided with a second inlet end and a second outlet end. The second inlet end of the liquid outlet valve 4 is connected to the liquid separator pump 3, and the second outlet end of the liquid outlet valve 4 is connected to the liquid separator block 5.

[0035] The liquid distribution block 5 includes multiple liquid distribution ports, and each liquid distribution port is equipped with a solenoid valve 6; wherein, the solenoid valve 6 can be adopted... Figure 1 NC valve in the middle.

[0036] The solution pump 3 is used to drive the target solution contained in the solution carrier 1 to be transmitted to the solution block 5 through the liquid inlet valve 2, the solution pump 3 and the liquid outlet valve 4, so as to be output by the multiple electromagnetic valves 6 of the solution block 5.

[0037] In a feasible embodiment, the multiple electromagnetic valves 6 of the multiple solution outlets are respectively connected with infusion needles with the same inner diameter.

[0038] In a feasible embodiment, the infusion needles connected with the multiple electromagnetic valves 6 are steel needles 7 made of stainless steel.

[0039] In a feasible embodiment, the liquid inlet valve 2 is a liquid inlet electromagnetic valve, and the liquid outlet valve 4 is a liquid outlet electromagnetic valve.

[0040] In a feasible embodiment, the solution pump 3 is a plunger pump, the first outlet end of the liquid inlet valve 2 is communicated with the plunger pump, and the second inlet end of the liquid outlet valve 4 is communicated with the plunger pump.

[0041] In a feasible embodiment, the solution pump 3 is a peristaltic pump, the first outlet end of the liquid inlet valve 2 is communicated with the peristaltic pump, and the second inlet end of the liquid outlet valve 4 is communicated with the peristaltic pump.

[0042] In a feasible embodiment, the solution pump 3 is a constant pump, the first outlet end of the liquid inlet valve 2 is communicated with the constant pump, and the second inlet end of the liquid outlet valve 4 is communicated with the constant pump.

[0043] In a feasible embodiment, the solution pump 3 is a syringe pump, the first outlet end of the liquid inlet valve 2 is communicated with the syringe pump, and the second inlet end of the liquid outlet valve 4 is communicated with the syringe pump.

[0044] In a feasible embodiment, the first inlet end of the liquid inlet valve 2 is communicated with the bottom of the solution carrier 1 through an infusion tube.

[0045] As shown in Figure 3 In a feasible embodiment, a host computer 8 is further included, which is connected with the liquid inlet valve 2, the solution pump 3, the liquid outlet valve 4 and the multiple electromagnetic valves 6 respectively.

[0046] The host computer 8 drives the liquid inlet valve 2 to be opened and the liquid outlet valve 4 to be closed, so that the solution pump 3 sucks the target solution of the solution carrier 1 through the liquid inlet valve 2.

[0047] The host computer 8 drives the inlet valve 2 to close, the outlet valve 4 to open, and each of the solenoid valves 6 to open, so that the dispensing pump 3 outputs the target solution to each of the solenoid valves 6 via the outlet valve 4, so that the target solution is dispensed and output through the multiple solenoid valves 6 of the dispensing block 5.

[0048] The host computer 8 drives the solenoid valves 6 to open sequentially according to a preset order and time difference, so that each solenoid valve 6 outputs the same amount of target liquid.

[0049] Among them, such as Figures 1-4 As shown, inlet valve 2 is opened, and dispensing pump 3 draws the target solution from the solution carrier. After the solution is drawn, inlet valve 2 is closed, and outlet valve 4 and eight solenoid valves 6 are opened. Simultaneously, dispensing pump 3 injects liquid into dispensing block 5 through outlet valve 4, and dispensing and batch sampling are performed by infusion needles 7 connected through eight solenoid valves 6. At this time, the liquid volume output by each infusion needle 7 is weighed by a balance and sorted in ascending order to obtain a preset order. Then, the compensation amount (δV1, δV2...δV8; δV8 is 0) of each of the other infusion needles 7 is calculated based on the maximum liquid volume. The motion curve of dispensing pump 3 is shown in the figure. Figure 4 As shown, the displacement S during the acceleration phase is 1 / 2 at. 2 The compensation time (t1, t2, ..., t8) of each solenoid valve 6 can be obtained according to the displacement-volume conversion formula of the dispensing pump 3 as a preset time difference. Then, the host computer drives the solenoid valves to open sequentially according to the preset order and time difference. The compensation time refers to the delayed closing time of the corresponding solenoid valve 6 relative to the solenoid valve 6 with the maximum liquid volume. A balance is used to weigh the weight change of the object receiving infusion from each infusion needle 7 to determine the liquid volume output by each infusion needle 7. The objects receiving infusion from each infusion needle 7 can be identical containers.

[0050] Compared to existing technologies, the micro-liquid addition device of this invention can add the target solution in the solution carrier 1 by dispensing it through multiple dispensing ports of the dispensing block 5. This allows multiple targets to simultaneously obtain the target solution through their corresponding dispensing ports, improving the consistency of liquid dispensing. Moreover, each dispensing port is equipped with a solenoid valve 6, which can be controlled to better regulate the amount of liquid output from the corresponding dispensing port. The solenoid valve 6 is controlled by the host computer 8, so the host computer 8 can drive the solenoid valve 6 to open sequentially according to a preset order and time difference, so that each solenoid valve 6 outputs the same amount of target liquid, which can more effectively improve the consistency of liquid dispensing.

[0051] Although the embodiments of the present application have been shown and described, it is to be understood that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A micro-liquid addition device, characterized in that, The utility model relates to a kind of target solution distribution device, including: Solution carrier, liquid inlet valve, liquid distribution pump, liquid outlet valve and liquid distribution block; The solution carrier is equipped with target solution; The liquid inlet valve is equipped with first inlet end and first outlet end, the first inlet end of the liquid inlet valve is communicated with the solution carrier, and the first outlet end of the liquid inlet valve is communicated with the liquid distribution pump; The liquid outlet valve is equipped with second inlet end and second outlet end, the second inlet end of the liquid outlet valve is communicated with the liquid distribution pump, and the second outlet end of the liquid outlet valve is communicated with the liquid distribution block; The liquid distribution block includes a plurality of liquid distribution ports, each of which is equipped with a solenoid valve; The liquid distribution pump is used to drive the target solution in the solution carrier to be transmitted to the liquid distribution block via the liquid inlet valve, the liquid distribution pump and the liquid outlet valve, so that the target solution is distributed and output by the plurality of solenoid valves in the liquid distribution block.

2. The micro-liquid adding device according to claim 1, characterized by: Each solenoid valve of each liquid distribution port is respectively connected to an infusion needle with the same inner diameter.

3. The micro-liquid adding device according to claim 2, characterized by: The infusion needles connected to the solenoid valves are stainless steel needles.

4. The micro-liquid adding device according to claim 1, characterized by: The liquid inlet valve is a liquid inlet solenoid valve, and the liquid outlet valve is a liquid outlet solenoid valve.

5. The micro-liquid adding device according to claim 1, characterized by: The liquid distribution pump is a plunger pump, the first outlet end of the liquid inlet valve is communicated with the plunger pump, and the second inlet end of the liquid outlet valve is communicated with the plunger pump.

6. The micro-liquid adding device according to claim 1, characterized by: The liquid distribution pump is a peristaltic pump, the first outlet end of the liquid inlet valve is communicated with the peristaltic pump, and the second inlet end of the liquid outlet valve is communicated with the peristaltic pump.

7. The micro-liquid adding device according to claim 1, characterized by: The liquid distribution pump is a constant-volume pump, the first outlet end of the liquid inlet valve is communicated with the constant-volume pump, and the second inlet end of the liquid outlet valve is communicated with the constant-volume pump.

8. The micro-liquid adding device according to claim 1, characterized by: The liquid distribution pump is a syringe pump, the first outlet end of the liquid inlet valve is communicated with the syringe pump, and the second inlet end of the liquid outlet valve is communicated with the syringe pump.

9. The micro-liquid adding device according to claim 1, characterized by: The first inlet end of the liquid inlet valve is communicated with the bottom of the solution carrier through an infusion tube.

10. The micro-liquid adding device according to any one of claims 1 to 9, characterized in that: Further comprising a host computer, the host computer is connected to the liquid inlet valve, the liquid distribution pump, the liquid outlet valve and each solenoid valve respectively; The host computer drives the liquid inlet valve to open and the liquid outlet valve to close, so that the liquid distribution pump sucks the target solution in the solution carrier via the liquid inlet valve; The host computer drives the liquid inlet valve to close, the liquid outlet valve to open and each solenoid valve to open, so that the liquid distribution pump outputs the target solution to each solenoid valve via the liquid outlet valve, so that the target solution is distributed and output by the plurality of solenoid valves in the liquid distribution block; The host computer drives the solenoid valves to open in sequence according to a preset sequence and time difference, so that each solenoid valve outputs the same amount of target liquid.

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