Metering device for raw material medicine synthesis feeding

Abstract

The utility model relates to the technical field of bulk drug metering, in particular to a metering device for bulk drug synthesis feeding, which comprises a base and a bent block, the bent block is fixedly connected to the right side of the upper end of the base, a third servo motor is fixedly connected to the end of the bent block, and an electronic scale is mounted on the left side of the upper end of the base. A tray is placed in the center of the upper end of the electronic scale. Through cooperation of a tray lifting structure and a tray clamping structure, an output shaft of a second servo motor rotates to drive two clamping blocks to relatively slide on a second sliding rod until the inner walls of the clamping blocks abut against a transverse plate, and in this way, the left clamping block and the right clamping block fix a tray; the output shaft of the first servo motor rotates to drive the rectangular frame to move downwards, the rectangular frame moves to drive the tray to move towards the electronic scale in the connecting mode till the lower end of the tray makes contact with the electronic scale, and continuous sizing material metering can be conducted on the raw material medicine in the mode, so that the working efficiency is improved.

Description

Technical Field

[0001] This utility model relates to the field of active pharmaceutical ingredient (API) metering technology, specifically to a metering device for adding raw materials in API synthesis. Background Technology

[0002] The properties of active pharmaceutical ingredients (APIs), such as purity, particle size, and flowability, impose very strict requirements on their measurement during the synthesis process. High-purity APIs are key to ensuring drug quality and efficacy. Therefore, the amount added must be precisely controlled during the measurement process to avoid inaccurate content of active ingredients in the drug due to measurement errors.

[0003] For example, in the drug substance synthesis metering tank with authorization announcement number "CN221789158U", the drug substance enters the inner side of the lower enclosure through the discharge port. At this time, rotating the push bolt will cause the push bolt to move backward. When the push bolt moves backward, it can pull the moving block to move horizontally inside the fixed block. When the moving block moves gradually, the lower part of the upper enclosure can gradually leak out. However, in actual operation of the metering tank, the active pharmaceutical ingredient (API) can enter the chute between the moving block and the fixed block, i.e., the sliding space formed by the limiting groove and the limiting strip. As the API falls from the discharge port through the inner side of the enclosure and the inner side of the fixed block, it can enter the chute through the tiny gap between the moving block and the fixed block. Especially when the equipment frequently adjusts the discharge rate and the moving block moves frequently, once the API enters the chute, it will gradually accumulate in the chute over time and with continuous use of the equipment. The accumulated powder will change the sliding environment of the limiting strip in the limiting groove, increase friction, and hinder the smooth movement of the moving block. When the powder accumulates to a certain extent, it will cause the moving block to get stuck, making it impossible to accurately adjust the area of ​​the discharge port, thus affecting the accuracy of metering. Utility Model Content

[0004] The purpose of this invention is to solve the problem that in the actual operation of the metering tank, the raw material drug enters the groove between the moving block and the fixed block, which causes the moving block to get stuck and makes it impossible to accurately adjust the area of ​​the discharge port, thus affecting the accuracy of the metering. Therefore, a metering device for raw material drug synthesis and feeding is proposed.

[0005] To achieve the above objectives, this utility model provides the following technical solution:

[0006] Design a metering device for feeding raw materials in drug synthesis, including a base and a bent block. The bent block is fixedly connected to the upper right side of the base, and a third servo motor is fixedly connected to the end of the bent block. The output shaft of the third servo motor is fixedly connected to a first housing. The first housing has a tray lifting structure inside. An electronic scale is installed on the upper left side of the base, and a tray is placed at the upper center of the electronic scale.

[0007] Preferably, the pallet lifting structure includes a first servo motor, the outer wall of the first servo motor is fixedly connected to a first housing, the output shaft of the first servo motor is fixedly connected to a cam, both ends of the cam's rotating shaft are rotatably connected to the first housing through bearings, the end of the cam is fixedly connected to a first cylinder, the outer wall of the first cylinder is slidably connected to a groove frame, the inner walls of the left and right sides of the groove frame are slidably connected to a first slide rod, the upper and lower ends of the first slide rod are fixedly connected to the first housing, and the lower ends of the groove frame are fixedly connected to two rectangular frames, the outer walls of the rectangular frames are slidably connected to the first housing.

[0008] Preferably, the lower end of the rectangular frame is fixedly connected to two second housings, and the interior of the second housings is provided with a tray clamping structure.

[0009] Preferably, the pallet clamping structure includes a second servo motor, the outer wall of which is fixedly connected to a second housing, and a round rod fixedly connected to the output shaft of the second servo motor. Both ends of the round rod are rotatably connected to the second housing via bearings. A first bevel gear is fixedly connected to both sides of the outer wall of the round rod, and the first bevel gear meshes with a second bevel gear. The rotation shaft of the second bevel gear is rotatably connected to the second housing via bearings. A connecting rod is fixedly connected to the outer wall of the rotation shaft of the second bevel gear, and a second cylinder is fixedly connected to the end of the connecting rod. The outer wall of the second cylinder is slidably connected to a groove machined in the clamping block, and the inner wall of the clamping block is slidably connected to a second sliding rod.

[0010] Preferably, the inner wall of the clamping block abuts against the horizontal plate, and the end of the horizontal plate is fixedly connected to the tray.

[0011] Preferably, both ends of the second slide rod are fixedly connected to the second housing, and the outer wall of the clamping block is slidably connected to the second housing.

[0012] The present invention provides a metering device for feeding raw materials in pharmaceutical synthesis. The advantages are as follows: Through the cooperation of the pallet lifting structure and the pallet clamping structure, the output shaft of the second servo motor rotates, driving two connecting rods to rotate. The rotating connecting rods cause the second cylinder to slide within the groove processed in the clamping block, thereby causing the two clamping blocks to slide relative to each other on the second slide rod until the inner wall of the clamping block abuts against the horizontal plate. This method fixes the pallet in place for both sets of clamping blocks. The output shaft of the first servo motor rotates, driving the cam to rotate. The cam rotates, causing the first cylinder to slide left and right within the groove frame. Because the groove frame causes the first cylinder to slide left and right, the first cylinder causes the groove frame to slide up and down on the slide rod, thereby moving the rectangular frame downwards. This movement of the rectangular frame, through the above connection method, moves the pallet towards the electronic scale until the lower end of the pallet contacts the electronic scale. This method allows for continuous metering of the raw material, thereby improving work efficiency. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the structure of this utility model;

[0014] Figure 2 for Figure 1 A front sectional view;

[0015] Figure 3 for Figure 2 A front sectional view of the second shell in the middle;

[0016] Figure 4 for Figure 3 A partial right-side sectional view;

[0017] Figure 5 for Figure 1 A front sectional view of the first shell in the middle;

[0018] Figure 6 for Figure 5 Left sectional view.

[0019] In the diagram: 1. Base, 2. Tray, 3. Electronic scale, 4. First housing, 5. Tray lifting structure, 501. First servo motor, 502. Cam, 503. First cylinder, 504. Groove frame, 505. First slide bar, 506. Rectangular frame, 6. Third servo motor, 7. Bend block, 8. Second housing, 9. Tray clamping structure, 901. Second servo motor, 902. Round rod, 903. First bevel gear, 904. Second bevel gear, 905. Connecting rod, 906. Second cylinder, 907. Clamping block, 908. Second slide bar, 10. Bracket, 11. Horizontal plate. Detailed Implementation

[0020] The present invention will be further described below with reference to the accompanying drawings:

[0021] See attached document Figure 1-6 In this embodiment, a metering device for feeding raw material pharmaceuticals includes a base 1 and a bent block 7. The bent block 7 is fixedly connected to the upper right side of the base 1, and a third servo motor 6 is fixedly connected to the end of the bent block 7. The output shaft of the third servo motor 6 is fixedly connected to a first housing 4. A tray lifting structure 5 is provided inside the first housing 4. An electronic scale 3 is installed on the upper left side of the base 1. A tray 2 is placed at the upper center of the electronic scale 3. The lower end of a rectangular frame 506 is fixedly connected to a second housing 8. A tray clamping structure 9 is provided inside the second housing 8. The inner wall of the clamping block 907 abuts against a horizontal plate 11. The end of the horizontal plate 11 is fixedly connected to the tray 2. The lower end of the tray 2 is in contact with the electronic scale 3. The lower end of the electronic scale 3 is fixedly connected to the base 1. The electronic scale 3 is a high-precision 500g / 0.01g electronic scale with original calibration certificate from Zhongheng Measurement and Testing.

[0022] See attached document Figure 1 , Figure 2 , Figure 5 and Figure 6 The pallet lifting structure 5 includes a first servo motor 501. The outer wall of the first servo motor 501 is fixedly connected to the first housing 4. The output shaft of the first servo motor 501 is fixedly connected to a cam 502. The rotation of the output shaft of the first servo motor 501 drives the cam 502 to rotate. Both ends of the rotating shaft of the cam 502 are rotatably connected to the first housing 4 through bearings. The cam 502 rotates in the first housing 4 through the bearings. The end of the cam 502 is fixedly connected to a first cylinder 503. The outer wall of the first cylinder 503 is slidably connected to a groove frame 504. The first cylinder 503 slides in the groove frame 504.

[0023] The inner walls on both sides of the groove frame 504 are slidably connected to the first slide rod 505. The groove frame 504 slides on the first slide rod 505. The upper and lower ends of the first slide rod 505 are fixedly connected to the first housing 4. The two sides of the lower end of the groove frame 504 are fixedly connected to the rectangular frame 506. The outer wall of the rectangular frame 506 is slidably connected to the first housing 4. The rectangular frame 506 slides inside the first housing 4.

[0024] See attached document Figure 1 , Figure 2 , Figure 3 and Figure 4 The tray clamping structure 9 includes a second servo motor 901. The outer wall of the second servo motor 901 is fixedly connected to the second housing 8. The output shaft of the second servo motor 901 is fixedly connected to a round rod 902. Both ends of the round rod 902 are rotatably connected to the second housing 8 through bearings. The round rod 902 rotates inside the second housing 8 through the bearings. The two sides of the outer wall of the round rod 902 are fixedly connected to a first bevel gear 903. The rotation of the round rod 902 drives the first bevel gear 903 to rotate. The first bevel gear 903 meshes with a second bevel gear 904. The rotation of the first bevel gear 903 drives the second bevel gear 904 to rotate.

[0025] The rotating shaft of the second bevel gear 904 is rotatably connected to the second housing 8 via a bearing. The second bevel gear 904 rotates within the second housing 8 via the bearing. A connecting rod 905 is fixedly connected to the outer wall of the rotating shaft of the second bevel gear 904. The rotation of the second bevel gear 904 drives the connecting rod 905 to rotate. A second cylinder 906 is fixedly connected to the end of the connecting rod 905. The outer wall of the second cylinder 906 is slidably connected to the groove machined in the clamping block 907. The second cylinder 906 slides within the groove machined in the clamping block 907. The inner wall of the clamping block 907 is slidably connected to the second slide rod 908. The clamping block 907 slides on the second slide rod 908. Both ends of the second slide rod 908 are fixedly connected to the second housing 8. The outer wall of the clamping block 907 is slidably connected to the second housing 8. The clamping block 907 slides within the second housing 8.

[0026] Working principle:

[0027] Metering procedures for adding active pharmaceutical ingredients during synthesis:

[0028] Tray placement:

[0029] The operator places the horizontal plate 11 between the two clamping blocks 907, connects the external power supply to the second servo motor 901, and starts the second servo motor 901. The output shaft of the second servo motor 901 rotates, driving the round rod 902 to rotate (e.g., Figure 3 The rotation of the round rod 902 drives the two first bevel gears 903 to rotate, and the rotation of the first bevel gears 903 drives the two second bevel gears 904 to rotate. To be further explained, the two second bevel gears 904 rotate in opposite directions. The rotation of the second bevel gears 904 drives the two connecting rods 905 to rotate, and the rotation of the connecting rods 905 drives the second cylinder 906 to slide in the groove machined in the clamping block 907, so that the two clamping blocks 907 slide relative to each other on the second sliding rod 908 until the inner wall of the clamping block 907 abuts against the horizontal plate 11. The second servo motor 901 is turned off. In the above manner, both sets of clamping blocks 907 fix the tray 2.

[0030] When the external power supply of the third servo motor 6 is connected and the third servo motor 6 is started, the output shaft of the third servo motor 6 rotates, causing the first housing 4 to rotate (e.g., Figure 2 The first housing 4 rotates, causing the second housing 8 to rotate. The first housing 8 rotates, causing the horizontal plate 11 to rotate, thereby causing the tray 2 to rotate. When the tray 2 is rotated directly above the electronic scale 13, the third servo motor 6 is turned off.

[0031] When the external power supply of the first servo motor 501 is connected and the first servo motor 501 is started, the output shaft of the first servo motor 501 rotates, driving the cam 502 to rotate (e.g. Figure 6 The cam 502 rotates, causing the first cylinder 503 to slide left and right within the groove frame 504. Because the groove frame 504 causes the first cylinder 503 to slide left and right, the first cylinder 503 causes the groove frame 504 to slide up and down on the slide rod 505, thereby causing the rectangular frame 506 to move downward. The movement of the rectangular frame 506 drives the tray 2 to move towards the electronic scale 3 through the above connection method until the lower end of the tray 2 contacts the electronic scale 3, at which point the first servo motor 501 is turned off.

[0032] Measurement of active pharmaceutical ingredient:

[0033] The second servo motor 901 is started, and its output shaft reverses. Through the aforementioned connection method, the two clamping blocks 907 are moved away from the horizontal plate 11. The electronic scale 3 is then started. The electronic scale 3 selected is a high-precision 500g / 0.01g electronic scale from Zhongheng Measurement and Testing, with its original calibration certificate. The operator pours material onto the tray 2. Since the weight of the tray 2 is constant, the measurement of the raw material can be easily achieved by observing the readings on the electronic scale. Due to the clamping and releasing of the clamping blocks 907 on the tray 2, only the weight of the tray 2 on the electronic scale 3 is applied, resulting in more accurate measurement. Furthermore, in pharmaceutical production environments, the quality and purity requirements for pharmaceuticals are extremely high. If the tray is left on the electronic scale continuously, it will absorb dust and impurities from the surrounding environment. Because of the tiny particles, the tray is only placed on the electronic scale during use. After the left tray 2 has finished feeding the raw material, it is clamped and lifted in the manner described above. The third servo motor 6 is then started, and the right tray 2 is placed on the electronic scale 3 via the connection method described above. The left tray 2 is then removed and fed with the raw material to be synthesized. During the feeding process, the operator can place the new tray 2 in the two clamping blocks 907. The raw material can be continuously metered and fed in this way, thereby improving work efficiency. After the metering and feeding of the raw material to be synthesized is completed, the tray 2 is removed, and the electronic scale 3 is covered by an external cover. The tray 2 is then cleaned, and all power is turned off. This completes the working process of the metering device for raw material synthesis feeding.

[0034] Although the present invention has been illustrated and described with reference to preferred embodiments, those skilled in the art should understand that various changes in form and detail are possible within the scope of the claims.

Claims

1. A metering device for raw material drug synthesis feeding, comprising a base (1) and a bent block (7), the upper end of the right side of the base (1) is fixedly connected with the bent block (7), characterized in that: The end of the bending block (7) is fixedly connected with a third servo motor (6), the output shaft of the third servo motor (6) is fixedly connected with a first shell (4), the inside of the first shell (4) is provided with a tray lifting structure (5), the upper end left side of the base (1) is provided with an electronic scale (3), and the upper end center of the electronic scale (3) is provided with a tray (2).

2. The raw material drug synthesis charging metering device according to claim 1, characterized by: The tray lifting structure (5) comprises a first servo motor (501), the outer wall of the first servo motor (501) is fixedly connected with the first shell (4), the output shaft of the first servo motor (501) is fixedly connected with a cam (502), the both ends of the rotating shaft of the cam (502) are rotatably connected with the first shell (4) through bearings, the end of the cam (502) is fixedly connected with a first cylinder (503), the outer wall of the first cylinder (503) is slidably connected with a groove frame (504), the inner walls of the left and right sides of the groove frame (504) are slidably connected with first sliding rods (505), the upper and lower ends of the first sliding rods (505) are fixedly connected with the first shell (4), and the both sides of the lower end of the groove frame (504) are fixedly connected with rectangular frames (506).

3. The bulk drug substance synthesis charging metering device of claim 2, wherein: The lower end of the rectangular frame (506) is fixedly connected with two second shells (8), and the inside of the second shell (8) is provided with a tray clamping structure (9).

4. The bulk drug substance synthesis charging metering device of claim 3, wherein: The tray clamping structure (9) comprises a second servo motor (901), the outer wall of the second servo motor (901) is fixedly connected with the second shell (8), the output shaft of the second servo motor (901) is fixedly connected with a round rod (902), the both ends of the round rod (902) are rotatably connected with the second shell (8) through bearings, the both sides of the outer wall of the round rod (902) are fixedly connected with first bevel gears (903), the first bevel gears (903) are meshedly connected with second bevel gears (904), the rotating shaft of the second bevel gears (904) is rotatably connected with the second shell (8) through a bearing, the outer wall of the rotating shaft of the second bevel gears (904) is fixedly connected with connecting rods (905), the ends of the connecting rods (905) are fixedly connected with second cylinders (906), the outer wall of the second cylinders (906) is slidably connected with sliding grooves processed in clamping blocks (907), and the inner wall of the clamping blocks (907) is slidably connected with second sliding rods (908).

5. The bulk drug substance synthesis charging metering device of claim 4, wherein: The inner wall of the clamping block (907) is tightly abutted against a cross plate (11), and the end of the cross plate (11) is fixedly connected with the tray (2).

6. The bulk drug substance synthesis charging metering device of claim 5, wherein: The both ends of the second sliding rod (908) are fixedly connected with the second shell (8), and the outer wall of the clamping block (907) is slidably connected with the second shell (8).

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