Immunoassay microwell plate sample adding auxiliary device

Abstract

The utility model discloses an immunoassay microwell plate sample adding auxiliary device which comprises a bottom plate, a placing groove is formed in the middle of the upper surface of the bottom plate, a microwell plate is placed in the placing groove, two supports which are distributed oppositely are arranged at the left end of the upper surface of the bottom plate, a cover plate is rotationally connected between the two supports through a rotating shaft, and the cover plate is connected with the bottom plate through a rotating shaft. The cover plate is positioned right above the micro-pore plate, and a plurality of sample adding holes which are distributed in one-to-one correspondence with the reaction holes in the micro-pore plate are formed in the surface of the cover plate. Through the arrangement of the light sensor and the indicator lamp, a worker can clearly know which holes are filled with an immunodetection reaction solution and which holes are not filled with the immunodetection reaction solution at a glance, so that the phenomena of missed adding and excessive adding can be effectively prevented, errors of detection data caused by excessive adding or missed adding are avoided, and the detection efficiency is improved. Therefore, the waste of resources and manpower is avoided, and the working efficiency is greatly improved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to immunology inspection equipment technical field especially relates to a kind of immunological test micro-well plate sample adding auxiliary device. BACKGROUND

[0002] Micro-well plate is a kind of high-throughput laboratory supplies, usually used for high-throughput screening, analysis and store biological samples, often used as the container of the detected object and reactant in immunological test, since the number of micro-well plate is larger and more intensive, since the sample used is colorless transparent liquid, in the process of sample adding, it is easy to appear to add, add more and other mistakes, cause resource waste, it can also lead to detection task failure, micro-well plate will be marked on the layout through coordinate form, but still need to rely on artificial memory, it is very inconvenient UTILITY MODEL CONTENT

[0003] The utility model aims at providing a kind of immunological test micro-well plate sample adding auxiliary device to solve the technical problem proposed in the background art.

[0004] To achieve the above object, the specific technical scheme of the utility model is as follows: a kind of immunological test micro-well plate sample adding auxiliary device, including bottom plate, the middle part of the upper surface of the bottom plate is provided with placing groove, the micro-well plate is placed in the placing groove, the upper surface left end of the bottom plate is provided with two opposite distribution's support, two the support is rotatably connected with cover plate through pivot between two The cover plate is located directly above micro-well plate, and the surface of the cover plate is provided with a plurality of sample adding holes corresponding to the distribution of reaction hole on micro-well plate, each sample adding hole inner wall is mounted with indicator light and photosensor, the U-shaped frame that can be freely moved along the length direction is set on the bottom plate, the horizontal section surface of the U-shaped frame is provided with through hole corresponding to the distribution of sample adding hole in the width direction of cover plate along its length direction, each through hole is provided with sample adding tube, the top end of each sample adding tube is provided with air bag, and the U-shaped frame is provided with clamping mechanism for simultaneously extruding multiple air bags.

[0005] Preferably, the size of the micro-well plate is consistent with the size of the placing groove, and recesses are provided on both sides of the upper surface of the bottom plate in the placing groove.

[0006] Preferably, the bottom of the cover plate is provided with a plurality of through pipes corresponding to the distribution of sample adding holes, and the bottom of the through pipe is in contact with the upper surface of the micro-well plate.

[0007] Preferably, the left side of the upper surface of the cover plate is provided with a control shell, and a single-chip microcomputer and a battery are respectively arranged in the control shell, and the single-chip microcomputer is electrically connected with each indicator light and photosensor.

[0008] Preferably, the upper surface of the two long edges of the bottom plate is provided with a T-shaped groove, and the bottom of the two vertical sections of the U-shaped frame is provided with a T-shaped block in sliding connection with the T-shaped groove.

[0009] Preferably, the upper surface of the bottom plate is provided with a plurality of scale grooves distributed in one-to-one correspondence with the sample addition holes on the long edges, and the side wall of the U-shaped frame is provided with a pointer.

[0010] Preferably, the clamping mechanism comprises two oppositely distributed clamping plates, a bidirectional screw rod and a sliding rod, one end of the clamping plate is provided with a threaded hole in threaded connection with the bidirectional screw rod, the other end is provided with a sliding hole in sliding connection with the sliding rod, both ends of the bidirectional screw rod and the sliding rod are connected with both ends of the U-shaped frame through an L-shaped frame, the bidirectional screw rod is rotatably connected with the L-shaped frame through a bearing, one end of the bidirectional screw rod is provided with a knob, a spring is sleeved on the sliding rod, the spring is located between the two clamping plates, and the two clamping plates are located on both sides of the air bag.

[0011] The immune detection micro-hole plate sample addition auxiliary device has the following advantages:

[0012] 1. The utility model discloses a light sensor and the setting of pilot lamp, when having immune detection reaction solution to flow out through the mouth part of sample addition pipe, through the sample addition hole, the light sensor in the sample addition hole senses the signal, at this moment, the pilot lamp in the sample addition hole is controlled by singlechip and is lit, and the pilot lamp in the sample addition hole that has not added immune detection reaction solution is in the extinguishing state, at this moment, the staff can clearly know which hole adds immune detection reaction solution, and which hole does not add immune detection reaction solution, and the phenomenon of missing and adding can be effectively prevented, the test data is avoided to appear the error because of adding or missing, causes the waste of resources and manpower, and the working efficiency is greatly improved.

[0013] 2. The utility model discloses a knob is rotated, makes the bidirectional screw rod rotate, under the action of the sliding rod, make two clamping plates approach each other simultaneously, thereby extruding the air bag, the immune detection reaction solution in the sample addition pipe is extruded, and through the setting of the clamping mechanism, a plurality of sample addition pipes can be controlled to extrude immune detection reaction solution simultaneously, the working efficiency is greatly improved, time is saved, and the phenomenon of missing and adding can be avoided.

[0014] 3. Through the setting of the pointer and the scale groove, when the pointer is aimed, it is guaranteed that the sample addition pipe is just above the sample addition hole, and the phenomenon of deviation of the sample addition pipe and the sample addition hole can be effectively prevented. BRIEF DESCRIPTION OF DRAWINGS

[0015] In order to more clearly illustrate the technical scheme of the embodiments of the present application, the drawings needed in the embodiments will be briefly introduced as follows, and it should be understood that the following drawings only show some embodiments of the present application, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0016] Figure 1 It is a schematic diagram of the overall structure of the present application.

[0017] Figure 2 It is Figure 1 It is an enlarged view of A in the figure.

[0018] Figure 3 It is a schematic diagram of the structure of the cover plate in the present application.

[0019] Figure 4 It is a schematic diagram of the structure of the bottom plate in the present application.

[0020] Figure 5 It is a schematic diagram of the structure of the clamping mechanism in the present application.

[0021] Marked in the figure: 1, bottom plate; 2, cover plate; 3, sample hole; 4, control shell; 5, support; 6, groove; 7, T-shaped groove; 8, scale groove; 9, U-shaped frame; 10, sample tube; 11, air bag; 12, bidirectional screw; 13, slide bar; 14, spring; 15, clamping plate; 16, pointer; 17, indicator light; 18, light sensor; 19, conducting tube; 20, microwell plate; 21, placement groove; 22, T-shaped block; 23, through hole. DETAILED DESCRIPTION

[0022] In the following, only some exemplary embodiments are simply described. As those skilled in the art can realize, the described embodiments can be modified in various different ways without departing from the spirit or scope of the embodiments of the present application. Therefore, the drawings and the description are considered to be exemplary in nature rather than limiting.

[0023] In the description of the embodiments of the present application, it should be understood that the orientation or positional relationship indicated by the terms "length", "vertical", "horizontal", "top", "bottom" and the like is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the embodiments of the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the indicated device or element must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the embodiments of the present application.

[0024] In addition, the terms "first", "second", etc. are used only for the purpose of description and should not be understood as indicating or implying relative importance or implying a number of the technical features indicated. Therefore, the features defined as "first", "second" can explicitly or implicitly include one or more of the features. In the description of the embodiments of the present application, the meaning of "a plurality of" is two or more than two, unless otherwise specifically defined.

[0025] In the embodiments of the present application, unless otherwise specifically defined and limited, the terms "mounting", "connecting", "connecting", "fixing" and the like should be understood in a broad sense, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanically connected, or it can be electrically connected, or it can be communicated; it can be directly connected, or it can be indirectly connected through an intermediate medium, it can be the communication or interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the embodiments of the present application can be understood according to the specific circumstances.

[0026] The following disclosure provides many different embodiments or examples for implementing different structures of the embodiments of the present application. In order to simplify the disclosure of the embodiments of the present application, the components and settings of specific examples are described below. Of course, they are only examples, and the purpose is not to limit the embodiments of the present application. In addition, the embodiments of the present application can refer to the same reference numerals and / or reference letters in different examples, and such repetition is for the purpose of simplification and clarity, which itself does not indicate the relationship between the various embodiments and / or settings discussed.

[0027] In order to better understand the purpose, structure and function of the present application, the immune test micro-hole plate sample auxiliary device will be further described in detail below in combination with the drawings.

[0028] As Figures 1-5As shown, the utility model discloses an immune inspection microwell plate auxiliary device that adds sample, including bottom plate 1, the upper surface middle part of bottom plate 1 is provided with placing groove 21, and the microwell plate 20 is placed in placing groove 21, and the size of microwell plate 20 is consistent with the size of placing groove 21, and the upper surface of bottom plate 1 is provided with recess 6 on both sides of placing groove 21, and the setting of recess 6 is convenient for the taking and placing of microwell plate 20. The upper surface left end of bottom plate 1 is provided with two opposite distribution's support 5, and the cover plate 2 is rotatably connected through the pivot between two supports 5, and the cover plate 2 is located just above microwell plate 20, and the surface of cover plate 2 is provided with a plurality of sample adding holes 3 that are distributed one-to-one with the reaction holes on microwell plate 20, and the bottom of cover plate 2 is provided with a plurality of through pipes 19 that are distributed one-to-one with the sample adding holes, and the bottom of through pipe 19 contacts the upper surface of microwell plate 20, and the setting of through pipe 19 plays the role of auxiliary support for cover plate 2, so that when the bottom of through pipe 19 contacts the upper surface of microwell plate 20, the cover plate 2 is just above microwell plate 20, and each sample adding hole 3 is just aligned with each reaction hole of microwell plate 20. The inner wall of each sample adding hole 3 is provided with indicating lamp 17 and photosensitive sensor 18, and the upper surface left side of cover plate 2 is provided with control shell 4, and the control shell 4 is provided with single-chip microcomputer and battery respectively, and the single-chip microcomputer is electrically connected with each indicating lamp 17 and photosensitive sensor 18 respectively, when the immune detection reaction solution flows out through the mouth of sample adding pipe 10 and passes through sample adding hole 3, the photosensitive sensor 18 in sample adding hole 3 senses the signal, at this time, the indicating lamp 17 in sample adding hole 3 is controlled to light up by single-chip microcomputer, and the indicating lamp 17 in sample adding hole 3 without adding immune detection reaction solution is in the extinguishing state, at this time, the staff can clearly know which hole adds immune detection reaction solution and which hole does not add immune detection reaction solution, and it is obvious at a glance, can effectively prevent the phenomenon of missing and adding, avoid the error of test data caused by adding or missing, cause the waste of resources and manpower, greatly improve work efficiency.

[0029] The bottom plate 1 is provided with a U-shaped frame 9 which can freely move along the length direction of the bottom plate 1, the upper surface of the two long edges of the bottom plate 1 is provided with a T-shaped groove 7, the bottom of the two vertical sections of the U-shaped frame 9 is provided with a T-shaped block 22 which is in sliding connection with the T-shaped groove 7, through the cooperation between the T-shaped block 22 and the T-shaped groove 7, the U-shaped frame 9 can freely move back and forth on the bottom plate 1, so that the sample adding tube 10 can be aligned with each sample adding hole 3. The upper surface of the front side of the bottom plate 1 is provided with a plurality of scale grooves 8 which are distributed in one-to-one correspondence with the sample adding holes 3 on the long edges, and the side wall of the U-shaped frame 9 is provided with a pointer 16, through the setting of the pointer 16 and the scale groove 8, when the pointer 16 is aligned, it is ensured that the sample adding tube 10 is just above the sample adding hole 3, which can effectively prevent the phenomenon of deviation of the sample adding tube 10 from the sample adding hole 3. The horizontal section surface of the U-shaped frame 9 is provided with a through hole 23 which is distributed in one-to-one correspondence with the sample adding holes 3 in the width direction of the cover plate 2 along the length direction of the U-shaped frame 9, each through hole 23 is provided with a sample adding tube 10, the top end of each sample adding tube 10 is provided with an air bag 11, and the U-shaped frame 9 is provided with a clamping mechanism for simultaneously extruding a plurality of air bags 11, the clamping mechanism comprises two oppositely distributed clamping plates 15, a bidirectional screw rod 12 and a sliding rod 13, one end of the clamping plate 15 is provided with a threaded hole which is in threaded connection with the bidirectional screw rod 12, the other end is provided with a sliding hole which is in sliding connection with the sliding rod 13, the two ends of the bidirectional screw rod 12 and the sliding rod 13 are connected with the two ends of the U-shaped frame 9 through L-shaped frames, and the bidirectional screw rod 12 is rotationally connected with the L-shaped frame through a bearing, one end of the bidirectional screw rod 12 is provided with a knob, the sliding rod 13 is sleeved with a spring 14, the spring 14 is located between the two clamping plates 15, and the two clamping plates 15 are located on the two sides of the air bag 11, by rotating the knob, the bidirectional screw rod 12 is rotated, under the action of the sliding rod 13, the two clamping plates 15 are simultaneously close to each other, so as to extrude the air bag 11, so that the immune detection reaction solution in the sample adding tube 10 can be extruded, and through the setting of the clamping mechanism, a plurality of sample adding tubes 10 can be controlled to extrude the immune detection reaction solution at the same time, which greatly improves the work efficiency, saves time, and avoids the phenomenon of missing or adding too much.

[0030] The working principle of the immune test microwell plate sample adding auxiliary device is as follows: the microwell plate 20 to be added with sample is placed in the placing groove 21, the cover plate 2 is covered, then the multiple sample adding tubes 10 are taken out respectively, the sealing nozzle at the lower end position is screwed out, the immune detection reaction solution is filled into the sample adding tube 10, then the sample adding tube 10 is placed in the through hole 23 of the U-shaped frame 9 again, the U-shaped frame 9 is pushed, the sample adding tube 10 is moved to the position of the microwell plate 20, in the moving process, the position of the pointer 16 outside the U-shaped frame 9 corresponding to the scale groove 8 can be referred to, when the pointer 16 corresponds to the scale groove 8, it is indicated that the lower end of the sample adding tube 10 is opposite to the reaction hole of the microwell plate 20, then the knob can be manually rotated, the bidirectional screw rod 12 is rotated, under the action of the sliding rod 13, the two clamping plates 15 are simultaneously close to each other, so as to extrude the air bag 11, the immune detection reaction solution in the sample adding tube 10 is extruded out, the immune detection reaction solution in the sample adding tube 10 is introduced into the reaction hole of the microwell plate 20 through the sample adding hole 3, so that the purpose of adding sample to the microwell plate 20 is realized, when the immune detection reaction solution flows out through the nozzle of the sample adding tube 10 and passes through the sample adding hole 3, the light sensing sensor 18 in the sample adding hole 3 senses the signal, at this time, the indicating lamp 17 in the sample adding hole 3 is lighted up under the control of the single-chip microcomputer, and the indicating lamp 17 in the sample adding hole 3 without adding the immune detection reaction solution is in an extinguished state, at this time, the worker can clearly know which hole adds the immune detection reaction solution and which hole does not add the immune detection reaction solution.

[0031] It can be understood that the utility model is described through some embodiments, and the person skilled in the art knows that various changes or equivalent replacements can be made to these features and embodiments without departing from the spirit and scope of the utility model. In addition, under the guidance of the utility model, these features and embodiments can be modified to adapt to specific conditions and materials without departing from the spirit and scope of the utility model. Therefore, the utility model is not limited by the specific embodiments disclosed here, and all embodiments falling within the scope of the claims of the application belong to the range protected by the utility model.

Claims

1. An immunological assay microplate pipetting aid, characterized by: The utility model provides a microplate automatic adding device, including bottom plate (1), the middle part of upper surface of bottom plate (1) is provided with and places the groove (21), the microplate (20) is placed in the placing groove (21), the upper surface left end of bottom plate (1) is provided with two opposite distribution's support (5), two support (5) between through the pivot rotation is connected with the cover plate (2), the cover plate (2) is located the just above microplate (20), and the surface of cover plate (2) is provided with a plurality of with microplate (20) on the reaction hole one-to-one distribution's sample well (3), every sample well (3) inner wall all are installed indicating lamp (17) and photosensitive sensor (18), bottom plate (1) is provided with the U-shaped frame (9) that can be along its length direction freely moves, the horizontal section surface of U-shaped frame (9) is provided with the through -hole (23) with cover plate (2) width direction sample well (3) one-to-one distribution along its length direction, every through -hole (23) all is provided with sample tube (10), every sample tube (10) top is provided with air bag (11), and U-shaped frame (9) is provided with the clamping mechanism for simultaneously extruding a plurality of air bags (11).

2. The immunological assay microplate sample loading aid of claim 1, wherein: The size of the microplate (20) is consistent with the size of the placing groove (21), and the upper surface of the bottom plate (1) is provided with a groove (6) on both sides of the placing groove (21).

3. The immunological assay microplate sample loading aid of claim 1, wherein: The bottom of the cover plate (2) is provided with a plurality of through pipes (19) corresponding to the sample wells, and the bottom of the through pipe (19) is in contact with the upper surface of the microplate (20).

4. The immunological assay microplate sample loading aid of claim 1, wherein: The left side of the upper surface of the cover plate (2) is provided with a control shell (4), and the control shell (4) is provided with a single-chip microcomputer and a battery respectively.

5. The immunodiagnostic microwell plate pipetting aid of claim 1, wherein: The upper surface of the two long edges of the bottom plate (1) is provided with a T-shaped groove (7), and the bottom of the two vertical sections of the U-shaped frame (9) is provided with a T-shaped block (22) slidably connected with the T-shaped groove (7).

6. The immunodiagnostic microwell plate pipetting aid of claim 1, wherein: The front side of the upper surface of the bottom plate (1) is provided with a plurality of scale grooves (8) corresponding to the sample wells on the long edges, and the side wall of the U-shaped frame (9) is provided with a pointer (16).

7. The immunodiagnostic microwell plate pipetting aid of claim 1, wherein: The clamping mechanism comprises two oppositely distributed clamping plates (15), a bidirectional screw rod (12) and a sliding rod (13), one end of the clamping plate (15) is provided with a threaded hole threadedly connected with the bidirectional screw rod (12), the other end is provided with a sliding hole slidably connected with the sliding rod (13), the two ends of the bidirectional screw rod (12) and the sliding rod (13) are connected with the two ends of the U-shaped frame (9) through L-shaped frames, and the bidirectional screw rod (12) is rotatably connected with the L-shaped frame through a bearing, one end of the bidirectional screw rod (12) is provided with a knob, the sliding rod (13) is sleeved with a spring (14), the spring (14) is located between the two clamping plates (15), and the two clamping plates (15) are located on both sides of the air bag (11).

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