Polypeptide coarse filtrate recovery device

Abstract

The utility model relates to the technical field of polypeptide coarse filtrate recovery devices, and discloses a polypeptide coarse filtrate recovery device. Comprising a device framework group, the device framework group comprises a device base body, a filtering group is arranged on the device base body, the filtering group comprises a first filtering plate, the first filtering plate is arranged at the upper end in the device framework group and is in sliding connection with the device base body, a second filtering plate is arranged below the first filtering plate, and the second filtering plate is in sliding connection with the device base body. The second filter plate is arranged in the middle of the interior of the device base body, the second filter plate is slidably connected with the device base body, a third filter plate is arranged below the second filter plate, and the third filter plate is arranged at the bottom end of the interior of the device base body and slidably connected with the device base body; according to the utility model, through the arrangement of the vibrating grading filtering group, the coarse filtrate can be effectively filtered when the polypeptide coarse filtrate is recycled.

Description

Technical Field

[0001] This utility model relates to the technical field of polypeptide coarse filtrate recovery devices, specifically a polypeptide coarse filtrate recovery device. Background Technology

[0002] Polypeptides are compounds formed by amino acids linked together by peptide bonds, and are intermediate products of protein hydrolysis. A compound formed by the dehydration condensation of two amino acid molecules is called a dipeptide; similarly, there are tripeptides, tetrapeptides, pentapeptides, etc. Polypeptides are typically compounds formed by the dehydration condensation of 10 to 100 amino acid molecules. Polypeptides require purification and separation processes to obtain the final polypeptide compound. Existing polypeptide purification equipment suffers from problems such as low purification levels and cumbersome purification procedures.

[0003] A search revealed existing technology (application number: CN202321449188.9), which describes "a polypeptide solution filtration instrument." This utility model includes a main body, with an outlet pipe, a fixing plate, an inlet pipe, and a pull rod respectively disposed on the outer side of the main body. An mounting plate is embedded in the rear surface of the fixing plate, a filter plate is fixedly disposed on the front side of the mounting plate, a tension spring is fixedly disposed on the top of the fixing plate, a mounting block is fixedly disposed on the top of the tension spring, a limit rod is fixedly disposed on the bottom left side of the mounting block, a groove is formed on the side of the top surface of the main body, a sealing cover is disposed on the top of the main body, and a pressure mechanism is disposed on the top of the sealing cover.

[0004] However, although existing technologies can increase the flow rate between the peptide solution and the filter plate pores, they still have some shortcomings: they cannot solve the problem of filter material accumulation and the filtration efficiency is slow. Utility Model Content

[0005] The purpose of this invention is to address the shortcomings of existing technologies by proposing a polypeptide coarse filtrate recovery device.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a polypeptide crude filtrate recovery device, comprising a device frame assembly, the device frame assembly including a device base, a filter assembly disposed on the device base, the filter assembly including a first filter plate disposed at the upper end of the device frame assembly and slidably connected to the device base, a second filter plate disposed below the first filter plate and disposed in the middle of the device base and slidably connected to the device base, and a third filter plate disposed below the second filter plate and disposed at the bottom of the device base. Furthermore, the filter plate three is slidably connected to the device base; the outer wall of the device base is provided with an oscillation group, the oscillation group includes a motor, the motor is fixedly installed at the bottom of one side of the outer wall of the device base, the output end of the motor is fixedly connected to a rotating shaft one, the rotating shaft one passes through and rotatably connects to the outer wall of the device base, and the end of the rotating shaft one away from the motor is fixedly connected to a bevel gear one, the bevel gear one meshes with a bevel gear two, the bevel gear two is fixedly connected through and through a rotating shaft two, the rotating shaft two is fixedly installed through and through an eccentric wheel, the eccentric wheel causes the filter plate one, filter plate two and filter plate three to slide on the inner wall of the device base through a locking block one.

[0007] As a further description of the above technical solution:

[0008] The inner wall of the device base is provided with three sets of grooves, and a second locking block and a second spring are provided in the grooves. One end of the second spring is fixedly connected to the inner wall of the device base, and the other end of the second spring is fixedly connected to the second locking block. The second spring is provided at both ends of the outer side of the second locking block.

[0009] As a further description of the above technical solution:

[0010] The device base has three sets of grooves on the inner wall near the rotating shaft 2, and a locking block 1 and a spring 1 are installed in the grooves. One end of the spring 1 is fixedly connected to the inner wall of the device base, and the other end of the spring 1 is fixedly connected to the locking block 1. Both ends of the outer wall of the locking block 1 are provided with spring 1.

[0011] As a further description of the above technical solution:

[0012] Both the second spring and the first locking block are fixedly provided with limiting grooves. The limiting grooves slidably connect the first filter plate, the second filter plate, and the third filter plate. Each of the first filter plate, the second filter plate, and the third filter plate is fixedly provided with a handle on one outer end for pulling, and the handle is located on the outside of the device base.

[0013] As a further description of the above technical solution:

[0014] The pore size of filter plate one is larger than that of filter plate two, and the pore size of filter plate two is larger than that of filter plate three.

[0015] As a further description of the above technical solution:

[0016] The rotating shaft 2 is equipped with three sets of eccentric wheels, and the three sets of eccentric wheels correspond to the position of the locking block 1. When the motor is started, the eccentric wheels on the rotating shaft 2 push the filter plate 1, filter plate 2 and filter plate 3 to move left and right.

[0017] As a further description of the above technical solution:

[0018] An inlet is fixedly installed at the top of the device base, a filtrate storage tank is installed at the bottom of the device base, and a drain valve is installed on the device base for discharging the filtered liquid.

[0019] This utility model has the following beneficial effects:

[0020] 1. By setting three layers of filter plates in the device, with the pore size of filter plate one, filter plate two and filter plate three decreasing sequentially, multi-stage filtration is formed, which can remove impurities of different particle sizes in the peptide coarse filtrate. The filtration is carried out step by step from large particles to small particles, which improves the filtration efficiency and filtration accuracy and ensures the purity of the final filtrate.

[0021] 2. By installing an oscillation assembly on the outer wall of the device substrate, including a motor, a rotating shaft, a bevel gear, and an eccentric wheel, the motor drives the rotating shaft to rotate, and the bevel gear drives the eccentric wheel to rotate. The eccentric wheel pushes the filter plate to move left and right, generating oscillation. This can effectively prevent impurities on the filter plate from clogging the filter holes, allowing the filtrate to pass through the filter plate more smoothly, improving the filtration speed and filtration effect, and increasing production efficiency. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of a polypeptide coarse filtrate recovery device proposed in this utility model;

[0023] Figure 2 This is a partial schematic diagram of the filter assembly of a polypeptide coarse filtrate recovery device proposed in this utility model;

[0024] Figure 3 This is a partial schematic diagram of the device architecture of a polypeptide coarse filtrate recovery device proposed in this utility model;

[0025] Figure 4 This is a cross-sectional view of the oscillating assembly of a polypeptide coarse filtrate recovery device proposed in this utility model;

[0026] Figure 5 This is a cross-sectional view of the filter assembly of a polypeptide coarse filtrate recovery device proposed in this utility model.

[0027] Legend:

[0028] 1. Device structure group; 11. Device base; 12. Liquid inlet; 13. Filtrate storage tank; 14. Drain valve; 2. Vibration group; 21. Motor; 22. Shaft 1; 23. Bevel gear 1; 24. Bevel gear 2; 25. Shaft 2; 26. Eccentric wheel; 3. Filtration group; 31. Spring 1; 32. Locking block 1; 33. Filter plate 1; 34. Limiting slide groove; 35. Locking block 2; 36. Spring 2; 37. Filter plate 2; 38. Filter plate 3. Detailed Implementation

[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0030] Reference Figures 1-5 This utility model provides a polypeptide crude filtrate recovery device, comprising: a device structure group 1, the device structure group 1 including a device base 11, a filter group 3 disposed on the device base 11, the filter group 3 including a first filter plate 33, the first filter plate 33 being disposed at the upper end within the device structure group 1 and slidably connected to the device base 11; a second filter plate 37 disposed below the first filter plate 33, the second filter plate 37 being disposed at the middle within the device base 11 and slidably connected to the device base 11; and a third filter plate 38 disposed below the second filter plate 37, the third filter plate 38 being disposed at the bottom end within the device base 11 and slidably connected to the device base 11. Body 11; an oscillation group 2 is provided on the outer wall of the device base 11. The oscillation group 2 includes a motor 21. The motor 21 is fixedly installed at the bottom of one side of the outer wall of the device base 11. The output end of the motor 21 is fixedly connected to a rotating shaft 22. The rotating shaft 22 passes through and rotatably connects to the outer wall of the device base 11. A bevel gear 23 is fixedly connected to the end of the rotating shaft 22 away from the motor 21. The bevel gear 23 meshes with a bevel gear 24. A rotating shaft 25 is fixedly connected through the bevel gear 24. An eccentric wheel 26 is fixedly installed through the rotating shaft 25. The eccentric wheel 26 causes the filter plate 33, the filter plate 37, and the filter plate 38 to slide on the inner wall of the device base 11 through a locking block 32.

[0031] In this embodiment, the device architecture group, the oscillation group, and the filtration group constitute the polypeptide coarse filtrate recovery device involved in this application, realizing a polypeptide coarse filtrate recovery device. The polypeptide coarse filtrate in this application can be used as long as it needs to be recovered. This application does not limit the specific type of polypeptide coarse filtrate.

[0032] In this embodiment, filter plate 33 is disposed at the upper end of the device substrate 11 to preliminarily filter large particulate impurities in the polypeptide coarse filtrate, reducing the burden on subsequent filter plates. Filter plate 37 is disposed in the middle of the device substrate 11. The filtration pore size of filter plate 37 is smaller than that of filter plate 33, which can intercept finer impurity particles and improve filtration accuracy. Filter plate 38 is disposed at the bottom of the device substrate 11 to finally filter tiny particulate impurities. Filter plate 38 has the smallest filtration pore size, which can ensure the purity of the final filtrate.

[0033] In this embodiment, the motor 21 starts, driving the rotating shaft 22 to rotate. Through the transmission of bevel gear 23 and bevel gear 24, the rotating shaft 25 rotates. The eccentric wheel 26 on the rotating shaft 25 pushes the filter plate 33, filter plate 37 and filter plate 38 to move left and right on the inner wall of the device base 11 through the locking block 32, producing a vibration effect. The vibration can effectively prevent impurities on the filter plate from clogging the filter holes, allowing the filtrate to pass through the filter plate more smoothly, thereby improving the filtration speed and filtration effect.

[0034] It should be noted that the filter plate is made of polytetrafluoroethylene (PTFE). PTFE filter plates have uniform micropore sizes and more micropores per unit area, which can effectively capture tiny particles in the air, providing high-efficiency filtration performance. They have an extremely low coefficient of friction, a smooth surface, and do not easily adhere to other substances. Furthermore, PTFE has excellent chemical stability, making it suitable for peptide filtration that requires high chemical stability and low contamination.

[0035] Specifically, the inner wall of the device base 11 is provided with three sets of grooves, and the grooves are provided with a second locking block 35 and a second spring 36. One end of the second spring 36 is fixedly connected to the inner wall of the device base 11, and the other end of the second spring 36 is fixedly connected to the second locking block 35. The second spring 36 is provided at both ends of the outer side of the second locking block 35.

[0036] In this embodiment, the second spring 36 connects the second locking block 35 to the inner wall of the device base 11, buffering the movement of the filter plate, ensuring smooth movement of the filter plate, and extending the service life of the device.

[0037] Specifically, three sets of grooves are provided on the inner wall of the device base 11 near the rotating shaft 25, and a locking block 32 and a spring 31 are provided in the grooves. One end of the spring 31 is fixedly connected to the inner wall of the device base 11, and the other end of the spring 31 is fixedly connected to the locking block 32. Both ends of the outer wall of the locking block 32 are provided with springs 31.

[0038] In a preferred embodiment, spring 31 connects the locking block 32 to the inner wall of the device base 11, so that the locking block 32 is reset when the eccentric wheel is not rotating, thus maintaining the normal operation of the device.

[0039] Specifically, a limiting groove 34 is fixedly provided on both spring 2 36 and block 1 32. The limiting groove 34 slidably connects filter plate 1 33, filter plate 2 37 and filter plate 38. A handle is fixedly provided on one outer end of filter plate 1 33, filter plate 2 37 and filter plate 38 for pulling, and the handle is located on the outside of the device base 11.

[0040] It should be noted that the filter plate slides within the device base 11 via the limiting groove 34, and the handle makes it convenient for operators to pull out the filter plate.

[0041] Specifically, the pore size of filter plate 1 33 is larger than that of filter plate 2 37, and the pore size of filter plate 2 37 is larger than that of filter plate 3 38.

[0042] As a preferred implementation method, the different pore sizes of filter plates 33, 37, and 38 are used to perform staged filtration of the peptide coarse filtrate. Large particles are first intercepted by filter plate 33, medium particles are intercepted by filter plate 37, and small particles are intercepted by filter plate 38. This multi-stage filtration of the filtrate effectively improves the purity of the filtrate and meets the recovery requirements.

[0043] Specifically, three sets of eccentric wheels 26 are provided on the second rotating shaft 25, and the three sets of eccentric wheels 26 correspond to the position of the first locking block 32. When the motor 21 is started, the eccentric wheels 26 on the second rotating shaft 25 push the first filter plate 33, the second filter plate 37 and the third filter plate 38 to move left and right.

[0044] It should be noted that after the motor 21 starts, the three sets of eccentric wheels 26 on the rotating shaft 25 rotate synchronously, pushing the corresponding locking block 32 respectively, so that the filter plate 33, filter plate 37 and filter plate 38 move left and right, solving the problem of filter material accumulation and improving filtration efficiency.

[0045] Specifically, an inlet 12 is fixedly installed on the top of the device base 11, a filtrate storage tank 13 is installed at the bottom inside the device base 11, and a drain valve 14 is installed on the device base 11 for discharging the filtered liquid.

[0046] In this embodiment, the polypeptide coarse filtrate enters the device through the inlet 12, and after being filtered by the filter plate, the filtrate flows into the filtrate storage tank 13. The filtered liquid can be discharged by opening the drain valve 14, which facilitates the collection and recovery of the filtrate and makes the operation convenient.

[0047] In use, when recovering the peptide coarse filtrate, the coarse filtrate is poured in through the inlet 12. The liquid is filtered as it passes through each stage of filter plates 33. The filtered liquid is collected in the filtrate storage tank 13 and discharged by opening the drain valve 14. The filtered material remains on the surface of each stage of filter plates 33 and can be collected by removing the filter plates 33. When the filtered material accumulates on the filter plates 33 and affects the filtration process, the motor 21 is turned on. The bevel gear 23 meshes with the bevel gear 24, causing the eccentric wheels 26 on the rotating shaft 25 to rotate. This, in turn, pushes the locking block 32 to move left and right. Under the movement of the locking block 32 and the locking block 35, the filter plate 33 vibrates, solving the problem of filtered material accumulation and improving filtration efficiency.

[0048] This utility model discloses a polypeptide coarse filtrate recovery device. By setting up a multi-stage filter plate, it can filter the coarse filtrate step by step, effectively removing impurities and particulate matter, and improving filtration accuracy. When the filtered material accumulates and affects the filtration effect, the motor drives the bevel gear transmission to rotate the eccentric wheel, which in turn drives the filter plate to generate an oscillating motion, promptly clearing the accumulated material on the filter plate and avoiding blockage, thereby ensuring the continuous and efficient operation of the filtration process and improving filtration efficiency.

[0049] Finally, it should be noted that all electrical components mentioned in this article are connected to an external main controller and 220V AC mains power. The main controller can be a conventional known device that can be controlled by a computer or other means. The detailed description of known functions and components is omitted in the specific implementation of this disclosure. In order to ensure the compatibility of the device, the operating methods used are consistent with the parameters of commercially available instruments.

[0050] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A polypeptide crude filtrate recovery apparatus, characterized by: The device architecture group (1) includes a device base body (11), a filter group (3) is arranged on the device base body (11), the filter group (3) includes a filter plate one (33), the filter plate one (33) is arranged at the upper end in the device architecture group (1), and the filter plate one (33) is slidably connected with the device base body (11), a filter plate two (37) is arranged below the filter plate one (33), the filter plate two (37) is arranged at the middle part in the device base body (11), and the filter plate two (37) is slidably connected with the device base body (11), a filter plate three (38) is arranged below the filter plate two (37), the filter plate three (38) is arranged at the bottom end in the device base body (11), and the filter plate three (38) is slidably connected with the device base body (11).

2. A polypeptide crude filtrate recovery device according to claim 1, wherein: The outer wall of the device base body (11) is provided with a vibration group (2), the vibration group (2) includes a motor (21), the motor (21) is fixedly arranged at the bottom end of one side of the outer wall of the device base body (11), the output end of the motor (21) is fixedly connected with a rotating shaft one (22), the rotating shaft one (22) penetrates the outer wall of the device base body (11) and is rotatably connected with the device base body (11), and the end of the rotating shaft one (22) away from the motor (21) is fixedly connected with a bevel gear one (23), the bevel gear one (23) meshes with a bevel gear two (24), the bevel gear two (24) is fixedly connected with a rotating shaft two (25) penetratingly, the rotating shaft two (25) is fixedly provided with an eccentric wheel (26) penetratingly, and the eccentric wheel (26) makes the filter plate one (33), the filter plate two (37) and the filter plate three (38) slide on the inner wall of the device base body (11) through a clamping block one (32).

3. A polypeptide crude filtrate recovery device according to claim 2, wherein: The inner wall of the device base body (11) is provided with three groups of grooves, and a clamping block two (35) and a spring two (36) are arranged in the grooves, one end of the spring two (36) is fixedly connected with the inner wall of the device base body (11), the other end of the spring two (36) is fixedly connected with the clamping block two (35), the outer side of the clamping block two (35) is provided with the spring two (36) at both ends, the inner wall of the side of the device base body (11) close to the rotating shaft two (25) is provided with three groups of grooves, and a clamping block one (32) and a spring one (31) are arranged in the grooves, one end of the spring one (31) is fixedly connected with the inner wall of the device base body (11), the other end of the spring one (31) is fixedly connected with the clamping block one (32), and the outer wall of the clamping block one (32) is provided with the spring one (31) at both ends.

4. A polypeptide crude filtrate recovery device according to claim 3, wherein: The spring two (36) and the clamping block one (32) are fixedly provided with a limiting sliding groove (34), the limiting sliding groove (34) is slidably connected with the filter plate one (33), the filter plate two (37) and the filter plate three (38), and the outer end of one side of the filter plate one (33), the filter plate two (37) and the filter plate three (38) is fixedly provided with a handle for pulling and the handle is arranged outside the device base body (11).

5. A polypeptide crude filtrate recovery device according to claim 4, wherein: The filter aperture of the filter plate one (33) is larger than that of the filter plate two (37), and the filter aperture of the filter plate two (37) is larger than that of the filter plate three (38).

6. A polypeptide crude filtrate recovery device according to claim 5, wherein: The second rotating shaft (25) is provided with three sets of eccentric wheels (26), and the three sets of eccentric wheels (26) correspond to the positions of the clamping blocks (32); when the motor (21) is started, the eccentric wheels (26) on the second rotating shaft (25) push the filter plates (33), (37) and (38) to move left and right.

7. A polypeptide crude filtrate recovery device according to claim 6, wherein: The top of the device base (11) is fixedly provided with a liquid inlet (12), the bottom of the device base (11) is provided with a filtrate storage tank (13), and the device base (11) is provided with a liquid discharge valve (14) for discharging the filtered liquid.

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