Batching system

By designing an automated batching system, the problem of tedious and time-consuming manual batching in bio-fermentation experiments was solved, achieving high-precision and automated solution preparation, reducing labor costs and improving operational stability.

CN223766314UActive Publication Date: 2026-01-06WUXI TMAXTREE BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202423279625.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-30
Publication Date
2026-01-06
Estimated Expiration
2034-12-30

AI Technical Summary

Technical Problem

The manual ingredient preparation process in existing bio-fermentation experiments is cumbersome, time-consuming, and has low precision, making it prone to operational errors. Furthermore, existing equipment cannot accurately control the amount of mother liquor used.

Method used

A batching system was designed, comprising a main unit, a loading module, and a batching module. It adopts an interactive control system and is equipped with a weighing sensor and an automatic loading head. As shown in Figure 2, it has a high degree of automation, is adaptable to multiple channels and various container sizes, and achieves precise control of the amount of mother liquor added and uniform mixing.

Benefits of technology

It achieves a high-precision, automated batching process, reduces labor costs, improves operational stability and accuracy, and meets diverse solution preparation needs.

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Abstract

The utility model discloses a batching system which comprises a main machine, a charging module and a batching module, the main machine comprises an interactive control system, a plurality of peristaltic pumps and a plurality of plunger pumps, a manual charging head is arranged on the outer side of the main machine, the charging module comprises a plurality of mother liquor bottles, weighing sensors and magnetic stirrers are arranged at the bottoms of the mother liquor bottles, and the batching module comprises a first movement module. A code scanner is arranged on the first movement module, an automatic charging head is arranged on the second movement module, a bearing platform is arranged between the first movement module and the second movement module, a collecting container is placed on the bearing platform, and a waste liquid collecting pipe is arranged on the outer side of the bearing platform; the device has the characteristics of high automation degree, multiple channels, high precision, high operation stability and the like.
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Description

Technical Field

[0001] This utility model relates to the field of batching equipment, specifically a batching system. Background Technology

[0002] Orthogonal experiments in bio-fermentation are a design method for studying multiple factors and levels. However, the actual manual preparation process is monotonous, tedious, and time-consuming, especially when preparing a large number of solutions with different factors and levels for systematic multi-factor and multi-level studies. These experimental operations require the experimenter to manually prepare the materials according to the protocol. This process relies on a lot of repetitive manual labor and also suffers from low precision, poor parallelism, and is prone to operational errors.

[0003] Some ingredient dispensing equipment exists on the market. For example, Chinese patent CN113755301A discloses a culture medium intelligent dispensing system and application method, which provides a technical solution: the fermentation equipment unit includes an intelligent weighing base and a fermenter. The intelligent weighing base is provided with multiple fermenter grooves for accommodating the fermenter. The fermenter grooves are arranged in rows and columns, and corresponding row and column labels are specified. A weighing module is installed in the fermenter groove of the intelligent weighing base. This solution, which places the weighing module at the bottom of the fermenter, cannot effectively control the amount of each mother liquor used. That is, if there is an error between the final actual total amount prepared and the calculated value, it is impossible to identify which mother liquor was added incorrectly and to correct it. Utility Model Content

[0004] This utility model provides a batching system, including a main unit, a loading module, and a batching module. The main unit includes an interactive control system, which includes a memory, a processor, and a computer program stored in the memory and executable on the processor. The main unit includes several peristaltic pumps and plunger pumps, and a manual loading head is provided on the outside of the main unit. The loading module includes several mother liquor bottles, with a weighing sensor and a magnetic stirrer configured at the bottom of each mother liquor bottle. The batching module includes a frame, with a first motion module at the bottom of the frame and a barcode scanner on the first motion module. A second motion module is configured at the top of the frame, with an automatic loading head on the second motion module. A support platform is provided between the first and second motion modules, and a collection container is placed on the support platform. A waste liquid collection pipe is provided on the outside of the support platform.

[0005] Optionally, the first motion module includes a first guide rail and a first motion part, the first motion part being slidably connected to the first guide rail, and a barcode scanner being slidably connected to the first motion part.

[0006] Optionally, a label is provided at the bottom of the collection container, and the support platform is made of transparent material.

[0007] Optionally, the second motion module includes a second guide rail, a second motion part, and a third motion part. The second motion part is slidably connected to the second guide rail, the third motion part is slidably connected to the second motion part, and the automatic loading head is mounted on the third motion part.

[0008] Optionally, the dispensing module includes a clamp for securing the collection container used in the dispensing process.

[0009] Optionally, the main unit includes a manual adjustment lever on its outer side, and the manual loading head is mounted on the end of the manual adjustment lever.

[0010] This invention features a weighing sensor installed below the mother liquor bottle, which can accurately control the amount of each mother liquor added; the design of automatic and manual filling heads provides two filling modes to meet diverse solution preparation needs; this invention has the characteristics of high automation, multi-channel, high precision, compatibility with multiple container sizes, and high operational stability, which can effectively reduce the labor cost of the preparation process. Attached Figure Description

[0011] The above and / or additional aspects and advantages of this invention will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:

[0012] Figure 1 This is a schematic diagram of the main structure of a batching system according to an embodiment of the present invention;

[0013] Figure 2 This is a schematic diagram of the loading module structure of a batching system according to an embodiment of the present invention;

[0014] Figure 3 This is a schematic diagram of the material dispensing module structure of a material dispensing system according to an embodiment of the present invention;

[0015] Figure 4 This is a schematic diagram of the internal structure of the main unit of a batching system according to an embodiment of the present invention;

[0016] Figure 5 This is a schematic diagram of the material dispensing module structure of a material dispensing system according to an embodiment of the present invention.

[0017] In the diagram: 1. Main unit; 2. Loading module; 3. Batching module; 11. Interactive control system; 12. Peristaltic pump; 13. Plunger pump; 14. Manual loading head; 15. Manual adjusting rod; 21. Small mother liquor bottle; 22. Large mother liquor bottle; 23. Weighing sensor; 24. Magnetic stirrer; 31. Frame; 32. First guide rail; 33. First moving part; 34. Barcode scanner; 35. Second guide rail; 36. Second moving part; 37. Third moving part; 38. Automatic loading head; 39. Supporting platform; 40. Collection container; 41. Waste liquid collection pipe. Detailed Implementation

[0018] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0019] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of the stated features. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0020] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, an electrical connection, or a connection that allows for communication; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0021] In the description of this utility model, unless otherwise expressly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0022] The following disclosure provides many different embodiments or examples for implementing various structures of this invention. To simplify the disclosure, specific examples of components and arrangements are described below. These are merely examples and are not intended to limit the scope of the invention. Furthermore, reference numerals and / or letters may be repeated in different examples; such repetition is for simplification and clarity and does not in itself indicate a relationship between the various embodiments and / or arrangements discussed. In addition, examples of various specific processes and materials are provided in this invention, but those skilled in the art will recognize the application of other processes and / or the use of other materials.

[0023] Please see Figure 1-5 This utility model provides a batching system, including a host 1, a loading module 2, and a batching module 3. The host 1 includes an interactive control system 11, which includes a memory, a processor, and a computer program stored in the memory and run on the processor. The operator inputs relevant instruction parameters through the computer program to determine the batching mode.

[0024] like Figure 2 As shown, the loading module 2 is equipped with 6 mother liquor bottles, including 2 large mother liquor bottles 22 with a volume of 5L and 4 small mother liquor bottles 21 with a volume of 1L. Typically, the 5L large mother liquor bottles 22 are used to hold mother liquors used in larger quantities, such as deionized water and basal culture medium. It should be noted that the two sizes of mother liquor bottles are not intended to limit this invention; the appropriate size of mother liquor bottle should be selected based on the volume of mother liquor used.

[0025] Correspondingly, each mother liquor bottle is connected to one plunger pump 13, and each large mother liquor bottle 22 is additionally connected to one peristaltic pump 12. If the amount of mother liquor used for each component is small, the plunger pump 13 is used by default to deliver the solution; if the amount of mother liquor used is large, it automatically switches to the peristaltic pump 12. In this embodiment, a single addition volume of 18 ml of a certain mother liquor is set as the critical value.

[0026] Each mother liquor bottle is equipped with a weighing sensor 23 and a magnetic stirrer 24 at the bottom. The weighing sensor 23 precisely controls the amount of each mother liquor added. Using the mass of the mother liquor at the metering front end to control the amount of each component added is more precise and controllable than metering the total weight of the prepared solution. The magnetic stirrer 24 is used to stir the mother liquor evenly.

[0027] The feeding module 3 includes a frame 31, with a first motion module at the bottom of the frame 31. A barcode scanner 34 is mounted on the first motion module. A support platform 39, made of transparent material, is positioned between the first and second motion modules. A collection container 40 is placed on the support platform 39, and a label is affixed to the bottom of the collection container 40. For collection containers 40 with a capacity of 1L or less, a label with a QR code is affixed to the bottom of the target reactor, and the collection containers 40 are then placed sequentially at the designated positions in the feeding module 2.

[0028] A second motion module is installed at the top of the frame 31, a manual loading head 14 is installed on the outside of the main unit 1, and an automatic loading head 38 is installed on the second motion module. Since the support platform 39 needs to hold a certain number of collection containers 40, the volume of a single collection container 40 cannot be too large; a collection container 40 of approximately 1L is suitable. The manual loading head 14 is suitable for preparing larger volumes of solution; during preparation, the loading head position is manually adjusted to align with the collection container 40. Thus, this embodiment of the invention provides both automatic and manual loading modes.

[0029] See Figure 5 A waste liquid collection pipe is installed on the outside of the support platform 39 to collect and discharge the waste liquid generated during initialization and loading.

[0030] In some embodiments, the second motion module is located at the top of the frame 31 and includes a second guide rail 35, a second motion part 36 and a third motion part 37. The second motion part 36 is slidably connected to the second guide rail 35 and the third motion part 37 is slidably connected to the second motion part 36. In this way, the second module can realize three-axis motion and drive the automatic loading head 38 to load materials into the collection container 40.

[0031] like Figure 1 As shown, in some embodiments, a manual adjustment rod 15 is provided on the outside of the main unit 1, and a manual feeding head 14 is provided at the end of the manual adjustment rod 15. In manual feeding mode, the position of the feeding head can be freely adjusted according to the position of the collection container 40, which is simple and convenient.

[0032] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of this utility model. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0033] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A dosing system comprising a host computer (1), a charging module (2) and a dosing module (3), characterized in that, The host (1) comprises an interactive control system (11) comprising a memory, a processor and a computer program stored on the memory and executable on the processor, the host (1) comprises a number of peristaltic pumps (12) and piston pumps (13), a manual loading head (14) is arranged outside the host (1); The loading module (2) comprises a number of mother liquor bottles, the bottom of the mother liquor bottles is provided with a weighing sensor (23) and a magnetic stirrer (24); The ingredient module (3) comprises a frame (31), the bottom of the frame (31) is provided with a first motion module, a code scanner (34) is arranged on the first motion module, the top of the frame (31) is provided with a second motion module, an automatic loading head (38) is arranged on the second motion module, a supporting platform (39) is arranged between the first motion module and the second motion module, a collection container (40) is placed on the supporting platform (39), and a waste liquid collection pipe (41) is arranged outside the supporting platform (39).

2. A dosing system according to claim 1, characterized in that The first motion module comprises a first guide rail (32) and a first motion part (33), the first motion part (33) is in sliding connection with the first guide rail (32), and the code scanner (34) is in sliding connection with the first motion part (33).

3. A dosing system according to claim 1, characterized in that The bottom of the collection container (40) is provided with a label, and the supporting platform (39) is made of transparent material.

4. A dosing system according to claim 1, characterized in that The second motion module comprises a second guide rail (35), a second motion part (36) and a third motion part (37), the second motion part (36) is in sliding connection with the second guide rail (35), the third motion part (37) is in sliding connection with the second motion part (36), and the automatic loading head (38) is installed on the third motion part (37).

5. A dosing system according to claim 1, characterized in that The host (1) comprises a manual adjusting rod (15), and the manual loading head (14) is installed at the end of the manual adjusting rod (15).

Citation Information

Patent Citations

  • Intelligent culture medium split charging system and application method

    CN113755301A