Cell separation box with cooling function

By incorporating a spring between a sliding component and a fixing component in the cell separation box, the bottom of the test tube abuts against the heat sink, thus solving the problem of epidermal growth factor activity being affected by the external environment, achieving the stability of epidermal growth factor activity, and promoting wound healing.

CN223766328UActive Publication Date: 2026-01-06JIANGSU REPATEC LIFE SCI CO LTD
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Patent Information

Application Number
CN202520064450.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-13
Publication Date
2026-01-06
Estimated Expiration
2035-01-13

AI Technical Summary

Technical Problem

The activity of epidermal growth factor is easily affected by the external environment, leading to a decline in the skin's healing ability.

Method used

A spring is installed between a sliding component and a fixed component in the cell separation box. The test tube is pressed down to compress the spring and rotated clockwise, so that the test tube contacts the sliding component and the fixed component. The bottom of the test tube abuts against the heat sink, and the low temperature is used to maintain the activity and stability of the epidermal growth factor.

Benefits of technology

By lowering the temperature in the test tube, the activity of epidermal growth factor is maintained, promoting wound healing and ulcer repair.

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Abstract

The utility model belongs to the field of enzymology or microbiology devices, and particularly relates to a cell separation box with a cooling function. The rotary table is rotationally arranged in the box body, a plurality of hanging barrels are arranged on the rotary table, strip-shaped sliding holes are formed in the side walls of the hanging barrels, and limiting holes are formed in the side faces of the sliding holes; the test tube is arranged in the hanging cylinder, a convex block is arranged on the outer wall of the test tube, and the convex block is arranged in the strip-shaped sliding hole in a sliding manner; a sliding piece and a fixing piece are arranged in a gap between the hanging barrel and the test tube, a spring is arranged between the sliding piece and the fixing piece, and a cooling fin is arranged at the bottom of the hanging barrel; the sliding piece moves downwards to compress the spring so that the protruding block can enter the limiting hole, and the bottom of the test tube can abut against the upper end face of the cooling fin. The test tubes in the cell separation box are pressed down and rotate clockwise, so that the convex blocks enter the limiting holes, and the bottoms of the test tubes are propped against the cooling fins, so that the temperature of epidermal growth factors in the test tubes is reduced.
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Description

Technical Field

[0001] This invention belongs to the field of enzymology or microbiology devices, and particularly relates to a cell separation box with a cooling function. Background Technology

[0002] When treating large-area skin wounds, skin cells and epidermal growth factors are often obtained from the patient's own skin and then applied to the wound site. For ease of operation, a cell separation kit for skin wound treatment is typically used. The cell separation kit includes a turntable and a baffle. The turntable has several hanging cylinders containing test tubes suitable for storing cell fluid and epidermal growth factors.

[0003] However, the activity of epidermal growth factor (EGF) is easily affected by the external environment. Reduced EGF activity can lead to decreased skin healing ability, thus affecting wound healing and ulcer repair.

[0004] Therefore, how to avoid the reduction of epidermal growth factor activity stored in cell separation boxes is a problem that urgently needs to be solved by those skilled in the art.

[0005] It should be noted that the information disclosed in this background section is only for understanding the background technology of the present application concept, and therefore, the above description is not considered to constitute prior art information. Utility Model Content

[0006] This disclosure provides a cell separation box with a cooling function, comprising:

[0007] Box body;

[0008] A turntable is rotatably mounted inside the box. Several hanging cylinders are provided on the turntable. The side wall of each hanging cylinder has a strip-shaped sliding hole, and the side of the sliding hole has a limit hole.

[0009] A test tube is placed inside a hanging cylinder, and the outer wall of the test tube is provided with a protrusion, which is slidably disposed in a strip-shaped sliding hole.

[0010] The gap between the hanging cylinder and the test tube is provided with a sliding component and a fixing component, a spring is provided between the sliding component and the fixing component, and a heat sink is provided at the bottom of the hanging cylinder;

[0011] The sliding member moves down to compress the spring so that the protrusion enters the limiting hole, so that the bottom of the test tube abuts against the upper surface of the heat sink.

[0012] In one alternative embodiment, the spring is sleeved on the outer wall of the test tube and its upper and lower ends abut against the sliding member and the fixing member, respectively.

[0013] In one alternative embodiment, the inner ring of the sliding member is connected to the outer wall of the test tube, and the outer ring has a gap with the inner wall of the hanging cylinder; and the outer ring of the fixing member is connected to the inner wall of the hanging cylinder, and the inner ring has a gap with the outer wall of the test tube.

[0014] In one optional embodiment, a temperature sensor is further disposed at the bottom of the test tube, the temperature sensor being electrically connected to the display and the control module; and,

[0015] The control module is configured to receive temperature data from the temperature sensor and transmit the data to the display.

[0016] In one optional embodiment, a baffle is provided above the turntable, and the distance between the baffle and the turntable is greater than the distance between the test tube opening and the turntable.

[0017] On the other hand, this disclosure also provides a cell separation box, characterized in that it includes:

[0018] Test tubes and hanging tubes;

[0019] The outer wall of the test tube is provided with a protrusion, the hanging cylinder is sleeved on the outer wall of the test tube and the side wall of the hanging cylinder is provided with a strip-shaped sliding hole, the side of the strip-shaped sliding hole is provided with a limit hole, and the protrusion is slidably disposed in the strip-shaped sliding hole.

[0020] An elastic component is provided between the hanging cylinder and the test tube, and

[0021] The bottom of the hanging cylinder is equipped with heat dissipation fins;

[0022] The test tube is pressed down to compress the elastic component and rotated clockwise to allow the protrusion to enter the limiting hole, so that the bottom of the test tube abuts against the upper surface of the heat sink.

[0023] In one alternative implementation, the resilient component includes:

[0024] The sliding component has an inner ring that connects to the outer wall of the test tube, while the outer ring has a gap with the inner wall of the hanging cylinder.

[0025] The fastener has an outer ring that connects to the inner wall of the hanging cylinder, while the inner ring has a gap with the outer wall of the test tube.

[0026] A spring is fitted onto the outer wall of the test tube, with its upper and lower ends abutting against the sliding and fixing parts, respectively.

[0027] In one optional embodiment, a temperature sensor is further disposed at the bottom of the test tube, the temperature sensor being electrically connected to the display and the control module; and,

[0028] The control module is configured to receive temperature data from the temperature sensor and transmit the data to the display.

[0029] The beneficial effects of this utility model are that the cell separation box has a sliding part and a fixing part between the test tube and the hanging tube, and a spring is provided between the sliding part and the fixing part. When the test tube is pressed down to compress the spring and rotated clockwise, the protrusion enters the limiting hole, so that the bottom of the test tube abuts against the heat sink, thereby reducing the temperature of the epidermal growth factor in the test tube and using the low temperature to keep the activity of the epidermal growth factor stable.

[0030] Other features and advantages of this invention will be set forth in the description which follows, and will be apparent in part from the description, or may be learned by practicing the invention. The objectives and other advantages of this invention are realized and obtained through the structures particularly pointed out in the description and drawings.

[0031] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, preferred embodiments are described in detail below with reference to the accompanying drawings. Attached Figure Description

[0032] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0033] Figure 1 A perspective view of a cell separation box with a cooling function provided in an embodiment of this disclosure;

[0034] Figure 2 A cross-sectional view of a cell separation box test tube and hanging tube with cooling function provided in an embodiment of this disclosure;

[0035] Figure 3 This is a schematic block diagram of a cell separation box temperature sensor, control module, and display with cooling function provided in an embodiment of the present disclosure.

[0036] In the picture:

[0037] 100. Box body; 200. Turntable; 210. Hanging cylinder; 211. Sliding hole; 212. Limiting hole; 213. Heat sink; 214. Fixing component; 220. Test tube; 221. Protrusion; 222. Sliding component; 223. Temperature sensor; 300. Spring; 400. Baffle; 500. Display. Detailed Implementation

[0038] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0039] In this document, when it is mentioned that a first component is located on a second component, this can mean that the first component can be directly formed on the second component, or that a third component can be inserted between the first and second components. Furthermore, in the accompanying drawings, the thickness of the components may be exaggerated or reduced for the purpose of effectively describing the technical content.

[0040] The terminology used herein is for the purpose of describing specific exemplary configurations only and is not intended to be limiting. As used herein, the singular articles “a,” “an,” and “the” may also be intended to include plural forms unless otherwise clearly stated herein. The terms “comprising,” “including,” and “having” are inclusive and thus specify the presence of features, steps, operations, elements, and / or components, but do not preclude the presence or addition of one or more other features, steps, operations, elements, components, and / or combinations thereof. The method steps, processes, and operations described herein should not be construed as requiring them to be performed in the specific order discussed or shown, unless specifically identified as such. Additional or alternative steps may be employed.

[0041] As used herein, the phrases “in one embodiment,” “according to one embodiment,” “in some embodiments,” etc., generally refer to the fact that a particular feature, structure, or characteristic following the phrase can be included in at least one embodiment of this disclosure. Therefore, a particular feature, structure, or characteristic can be included in more than one embodiment of this disclosure, such that these phrases do not necessarily refer to the same embodiment. As used herein, the terms “example,” “exemplary,” etc., are used to “serve as an example, instance, or illustration.” Any implementation, aspect, or design described herein as “example” or “exemplary” is not necessarily to be construed as preferred or superior to other implementations, aspects, or designs. Rather, the use of the terms “example,” “exemplary,” etc., is intended to present concepts in a specific manner.

[0042] Research has revealed a drawback of existing technologies: the activity of epidermal growth factor (EGF) is easily affected by the external environment. Reduced EGF activity can lead to decreased skin healing ability, thus affecting wound healing and ulcer repair.

[0043] Based on the above research, this disclosure provides a cell separation device with a cooling function.

[0044] The shortcomings of the above solutions are the result of the inventor's practical experience and careful research. Therefore, the discovery process of the above problems and the solutions proposed in this disclosure should be considered as the inventor's contribution to this disclosure.

[0045] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0046] The following detailed description, with reference to the accompanying drawings, describes some embodiments of the present invention. Unless otherwise specified, the following embodiments and features can be combined with each other.

[0047] See Figure 1 This disclosure provides a cell separation device with a cooling function, comprising: a box body 100; a turntable 200 rotatably disposed within the box body 100, a plurality of hanging cylinders 210 disposed on the turntable 200, the side wall of the hanging cylinders 210 having a strip-shaped sliding hole 211, and the side of the sliding hole 211 having a limiting hole 212; test tubes 220 disposed within the hanging cylinders 210, the test tubes 220 being suitable for storing epidermal growth factors, the outer wall of the test tubes 220 having a protrusion 221, the protrusion 221 being slidably disposed within the strip-shaped sliding hole 211.

[0048] See Figure 2 In some embodiments, a sliding member 222 and a fixing member 214 are provided in the gap between the hanging cylinder 210 and the test tube 220. A spring 300 is provided between the sliding member 222 and the fixing member 214, and a heat sink 213 is provided at the bottom of the hanging cylinder 210. The sliding member 222 moves down to compress the spring 300 so that the protrusion 221 enters the limiting hole 212, so that the bottom of the test tube 220 abuts against the upper end face of the heat sink 213. The heat sink 213 is suitable for reducing the temperature of the epidermal growth factor inside the test tube 220. At a lower temperature, the activity of the epidermal growth factor is relatively stable.

[0049] like Figure 2 As shown, the inner ring of the sliding member 222 is connected to the outer wall of the test tube 220, and there is a gap between the outer ring and the inner wall of the hanging cylinder 210, allowing the test tube 220 to rotate flexibly within the hanging cylinder 210. The outer ring of the fixing member 214 is connected to the inner wall of the hanging cylinder 210, and there is a gap between the inner ring and the outer wall of the test tube 220, allowing the test tube 220 to slide up and down within the hanging cylinder 210 when the sliding member 222 compresses the spring 300.

[0050] Please see Figure 3In some embodiments, a temperature sensor 223 is also provided at the bottom of the test tube 220. The temperature sensor 223 is electrically connected to the display 500 and the control module. The control module is configured to receive the temperature data from the temperature sensor 223 and transmit the data to the display 500. The temperature of the epidermal growth factor inside the test tube 220 can be clearly seen through the display 500. If the temperature is too low, the test tube 220 can be rotated counterclockwise, causing the protrusion 221 on the outer wall of the test tube 220 to slide out from the limiting hole 212. Due to the elasticity of the spring 300, the bottom of the test tube 220 separates from the upper surface of the heat sink 213. At this time, the temperature of the epidermal growth factor inside the test tube 220 will no longer decrease.

[0051] See also Figure 1 In some embodiments, a baffle 400 is provided above the turntable 200, and the distance between the baffle 400 and the turntable 200 is greater than the distance between the mouth of the test tube 220 and the turntable 200. By rotating the turntable 200, the test tube 220 can be rotated to a position below the baffle 400 to prevent external dust from entering the test tube 220.

[0052] In summary, this cell separation box uses a sliding member 222 and a fixing member 214 between the test tube 220 and the hanging cylinder 210. A heat sink 213 is provided at the bottom of the hanging cylinder 210. A spring 300 is provided between the sliding member 222 and the fixing member 214. When the test tube 220 presses down to compress the spring 300 and rotates clockwise, the protrusion 221 enters the limiting hole 212, thereby making the bottom of the test tube 220 abut against the upper end face of the heat sink 213, so as to reduce the temperature of the epidermal growth factor in the test tube 220 and use the low temperature to keep the activity of the epidermal growth factor stable.

[0053] In the description of the embodiments of this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0054] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating orientation or positional relationships, are based on the orientation or positional relationships shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, terms such as "first," "second," and other numerical terms used herein do not imply order or sequence unless expressly indicated herein. Therefore, without departing from the teachings of the exemplary embodiments, the first element, component, region, layer, or segment discussed above may be referred to as the second element, component, region, layer, or segment.

[0055] Spatially relative terms, such as “inside,” “outside,” “below,” “below,” “down,” “above,” “up,” etc., may be used herein to describe the relationship between one element or feature illustrated in the figures and another element or feature. In addition to the orientations depicted in the figures, spatially relative terms may be intended to cover different orientations of the device in use or operation. For example, if the device in the figure is flipped, an element described as “below” or “below” other elements or features would be oriented as “above” other elements or features. Thus, the example term “below” can cover both above and below orientations. The device may be oriented in other ways (rotated 90 degrees or in other orientations), and the spatially relative descriptors used herein are interpreted accordingly.

[0056] Based on the above-described preferred embodiments of this utility model, and through the foregoing description, those skilled in the art can make various changes and modifications without departing from the technical concept of this utility model. The technical scope of this utility model is not limited to the contents of the specification, but must be determined according to the scope of the claims.

Claims

1. A cell separation cassette having a cooling function, characterized by, The cell separation box with cooling function comprises a box body (100), a rotating table (200) arranged in the box body (100), a plurality of hanging barrels (210) arranged on the rotating table (200), a strip-shaped sliding hole (211) arranged on the side wall of the hanging barrel (210), a limiting hole (212) arranged on the side of the sliding hole (211), a test tube (220) arranged in the hanging barrel (210), a protrusion (221) arranged on the outer wall of the test tube (220), the protrusion (221) being arranged in the strip-shaped sliding hole (211) in a sliding manner, a sliding piece (222) and a fixing piece (214) arranged in the gap between the hanging barrel (210) and the test tube (220), a spring (300) arranged between the sliding piece (222) and the fixing piece (214), and a cooling fin (213) arranged at the bottom of the hanging barrel (210).

2. The cell separation box with cooling function according to claim 1, wherein the spring (300) is sleeved on the outer wall of the test tube (220) and abuts against the sliding piece (222) and the fixing piece (214) at the upper and lower ends respectively.

3. The cell separation box with cooling function according to claim 2, wherein the inner ring of the sliding piece (222) is connected with the outer wall of the test tube (220), and the outer ring is spaced apart from the inner wall of the hanging barrel (210); and the outer ring of the fixing piece (214) is connected with the inner wall of the hanging barrel (210), and the inner ring is spaced apart from the outer wall of the test tube (220).

4. The cell separation box with cooling function according to claim 3, wherein a temperature sensor (223) is further arranged at the bottom of the test tube (220), and the temperature sensor (223) is electrically connected with a display (500) and a control module; and the control module is configured to receive the temperature data of the temperature sensor (223) and transmit the data to the display (500).

5. The cell separation box with cooling function according to claim 1, wherein a baffle (400) is arranged above the rotating table (200), and the distance between the baffle (400) and the rotating table (200) is greater than the distance between the opening of the test tube (220) and the rotating table (200). The cell separation box with cooling function comprises a test tube (220) and a hanging barrel (210), the outer wall of the test tube (220) is provided with a protrusion (221), the hanging barrel (210) is sleeved on the outer wall of the test tube (220), a strip-shaped sliding hole (211) is arranged on the side wall of the hanging barrel (210), a limiting hole (212) is arranged on the side of the strip-shaped sliding hole (211), the protrusion (221) is arranged in the strip-shaped sliding hole (211) in a sliding manner, an elastic assembly is arranged in the gap between the hanging barrel (210) and the test tube (220), and a cooling fin (213) is arranged at the bottom of the hanging barrel (210). ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 6. A cell separation cassette, characterized in that, ​ ​ ​ ​ ​ The test tube (220) is pressed to compress the elastic assembly and rotates clockwise to make the protrusion (221) enter the limiting hole (212), so that the bottom of the test tube (220) abuts against the upper end surface of the heat dissipation fin (213).

7. The cell separation cartridge of claim 6, wherein, The elastic assembly comprises: a sliding member (222) having an inner ring connected to the outer wall of the test tube (220) and an outer ring having a gap with the inner wall of the hanging cylinder (210); a fixing member (214) having an outer ring connected to the inner wall of the hanging cylinder (210) and an inner ring having a gap with the outer wall of the test tube (220); a spring (300) sleeved on the outer wall of the test tube (220) and abutting against the sliding member (222) and the fixing member (214) at the upper and lower ends, respectively.

8. The cell separation cartridge of claim 7, wherein, The bottom of the test tube (220) is further provided with a temperature sensor (223), and the temperature sensor (223) is electrically connected with the display (500) and the control module; and The control module is configured to receive temperature data of the temperature sensor (223) and transmit the data to the display (500).