Online dilution device for blood analysis

Abstract

The utility model discloses an online dilution device for blood analysis, and mainly relates to the field of blood analysis. Comprising a mixing cavity, the mixing cavity is communicated with a plunger pump, a blood inlet pipe, a diluent inlet pipe and a liquid outlet pipe, the blood inlet pipe, the diluent inlet pipe and the liquid outlet pipe are all provided with control valves, the blood inlet pipe is provided with a sample temporary storage cavity, the diluent inlet pipe is provided with a diluent temporary storage cavity, and the sample temporary storage cavity is communicated with the diluent temporary storage cavity. A detection glass tube is arranged on the liquid outlet tube, a rotating shaft is rotationally connected into the mixing cavity, a turbine is arranged on the rotating shaft, and a plurality of stirring rods are arranged on the rotating shaft. The blood sample diluting and mixing device has the beneficial effects that the technical problems that the operation is complicated and potential safety hazards exist when the existing blood sample is diluted and mixed can be solved, the blood can be quickly diluted and mixed, the convenience and the accuracy of the diluting operation are improved, and the safety threat to detection personnel is avoided.

Description

Technical Field

[0001] This utility model relates to the field of blood analysis, specifically an online dilution device for blood analysis. Background Technology

[0002] Blood is the most commonly used sample in medical testing. Currently, in hospitals and disease control centers, human blood is frequently analyzed for testing or treatment purposes. Before blood analysis, it is usually necessary to thoroughly mix the reagents in the blood collection tube with the blood. Currently, the most common method is for medical staff to manually mix the blood according to a set ratio to achieve anticoagulation. This method is not only time-consuming and labor-intensive, but the mixing effect is also not ideal, potentially leading to inaccurate test results.

[0003] To address the aforementioned issues, many test tubes with pre-diluent have emerged on the market. Adding a pre-diluent blood sample or filling the tube to the designated position completes the dilution. However, this method requires the use of pipettes to add the blood sample, placing high demands on sampling and mixing ratios, and necessitating aseptic technique. It is difficult to achieve precise dilution. Furthermore, manual mixing of blood and diluent carries inherent safety risks due to the numerous uncertainties associated with blood samples. Therefore, the above mixing methods still present certain safety hazards and potential threats to the health of testing personnel. Consequently, the convenience and safety of existing blood sample dilution and mixing methods require further improvement. Utility Model Content

[0004] The purpose of this invention is to provide an online dilution device for blood analysis, which can solve the technical problems of complex operation and safety hazards in the dilution and mixing of existing blood samples, realize rapid dilution and mixing of blood, improve the convenience and accuracy of dilution operation, and avoid safety threats to testing personnel.

[0005] To achieve the above objectives, this utility model employs the following technical solution:

[0006] An online dilution device for blood analysis includes a mixing chamber, on which a plunger pump, a blood inlet pipe, a diluent inlet pipe, and an outlet pipe are connected. Each of the blood inlet pipe, diluent inlet pipe, and outlet pipe is equipped with a control valve. The blood inlet pipe is provided with a sample storage chamber, the diluent inlet pipe is provided with a diluent storage chamber, and the outlet pipe is provided with a detection glass tube. A rotating shaft is rotatably connected inside the mixing chamber, and a turbine is provided on the rotating shaft. Multiple stirring rods are provided on the rotating shaft.

[0007] Furthermore, the blood inlet pipe, diluent inlet pipe, and outlet pipe are all located at the bottom of the mixing chamber, and the turbine is located at the bottom of the rotating shaft.

[0008] Furthermore, a cleaning pipeline is also connected to the mixing chamber, and a pure water tank and a control valve are provided on the cleaning pipeline.

[0009] Furthermore, the cleaning pipeline is connected to the inlet of the plunger pump, and the control valve is located between the pure water tank and the plunger pump.

[0010] Furthermore, the plunger pump is equipped with a pressure sensor.

[0011] Furthermore, the control valve is a pinch valve.

[0012] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0013] 1. This utility model has a plunger pump, a blood inlet pipe, a diluent inlet pipe, and an outlet pipe connected to the mixing chamber. The blood inlet pipe has a sample storage chamber, and the diluent inlet pipe has a diluent storage chamber. The plunger pump draws a specified volume of blood sample into the sample storage chamber and a specified volume of diluent into the diluent storage chamber. Then, the blood sample in the sample storage chamber and the diluent in the diluent storage chamber are drawn into the mixing chamber for mixing. The mixed liquid enters the detection glass tube through the outlet pipe, realizing rapid mixing of blood sample and diluent. The volume of blood sample and diluent drawn is more accurate, greatly improving the convenience and accuracy of blood dilution and mixing. Moreover, the mixing process does not require the testing personnel to come into contact with the blood sample, greatly improving the safety of operation and avoiding the safety threat that blood pressure samples may pose to the testing personnel.

[0014] 2. A rotating shaft is connected to the mixing chamber, and the shaft is equipped with a turbine and multiple stirring rods. With this structure, when the blood sample and diluent enter the mixing chamber, the liquid driven by the turbine drives the rotating shaft to rotate, which in turn causes the multiple stirring rods on the shaft to mix and stir the liquid. This allows the blood sample and diluent to be automatically and uniformly mixed without the need for manual mixing intervention, which greatly improves the uniformity of mixing and further enhances the convenience of blood dilution mixing. Attached Figure Description

[0015] Appendix Figure 1 This is a schematic diagram of the structure of this utility model.

[0016] Appendix Figure 2 This is a schematic diagram of the internal structure of the mixing chamber of this utility model.

[0017] Appendix Figure 3 This is an appendix to this utility model. Figure 2 A cross-sectional view along the AA direction.

[0018] The labels shown in the attached diagram:

[0019] 1. Mixing chamber; 2. Plunger pump; 3. Blood inlet pipe; 4. Diluent inlet pipe; 5. Outlet pipe; 6. Control valve; 7. Sample storage chamber; 8. Diluent storage chamber; 9. Detection glass tube; 10. Rotary shaft; 11. Turbine; 12. Stirring rod; 13. Cleaning pipeline; 14. Pure water tank; 15. Pressure sensor. Detailed Implementation

[0020] The present invention will be further illustrated below with reference to specific embodiments. It should be understood that these embodiments are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that after reading the teachings of this invention, those skilled in the art can make various alterations or modifications to the present invention, and these equivalent forms also fall within the scope defined in this application.

[0021] Reference Figure 1 and Figure 2This utility model describes an online dilution device for blood analysis. The main structure includes a mixing chamber 1, which is used to mix blood samples and diluents to dilute and mix the blood samples, preparing them for subsequent blood pressure analysis. The mixing chamber 1 is connected to a plunger pump 2, a blood inlet pipe 3, a diluent inlet pipe 4, and an outlet pipe 5. The blood sample enters the mixing chamber 1 through the blood inlet pipe 3, and the diluent enters the mixing chamber 1 through the diluent inlet pipe 4. The plunger pump 2 can be a commonly used 10 ml plunger pump or other models. The outlet pipe 5 is used to discharge the mixed liquid from the mixing chamber 1. The blood inlet pipe 3, diluent inlet pipe 4, and outlet pipe 5 are all equipped with... A control valve 6 is provided, which can control the opening and closing of the above three pipelines. The blood inlet pipe 3 is provided with a sample storage chamber 7, preferably a puncture needle, which is inserted into the sample tube to extract and temporarily store the blood sample. The diluent inlet pipe 4 is provided with a diluent storage chamber 8, preferably used to temporarily store a specified volume of diluent. The outlet pipe 5 is provided with a detection glass tube 9, which is used to store the diluted blood sample. The liquid in the detection glass tube 9 can be directly analyzed and detected later. A rotating shaft 10 is rotatably connected to the mixing chamber 1 via a bearing. A turbine 1 is fixed to the rotating shaft 10 by welding or bolts. 1. Multiple stirring rods 12 are fixed to the rotating shaft 10 by welding or bolts. Preferably, the mixing chamber 1 has a cylindrical structure, allowing the liquid flow to accurately drive the turbine 11 and the rotating shaft 10. When drawing blood samples, this structure closes the control valves 6 on the diluent inlet pipe 4 and outlet pipe 5, and opens the control valve 6 on the blood inlet pipe 3. The plunger pump 2 draws a specified volume of blood sample into the sample storage chamber 7. Then, the control valve 6 on the blood inlet pipe 3 is closed, and the control valve 6 on the diluent inlet pipe 4 is opened. The plunger pump 2 draws a specified volume of diluent into the diluent storage chamber 8. Then, the control valve 6 on the diluent inlet pipe 4 is also closed. The system is shut down, and the plunger pump 2 simultaneously draws the liquid from the sample storage chamber 7 and the diluent storage chamber 8 into the mixing chamber 1 for mixing and dilution. During this process, the liquid flows in the mixing chamber 1, and when the flowing liquid comes into contact with the turbine 11, it drives the turbine 11 and the rotating shaft 10 to rotate. This causes the stirring rod 12 on the rotating shaft 10 to mix and stir the liquid, thereby achieving accurate and uniform mixing of the blood sample and the diluent. The volume of the blood sample and the diluent drawn is more accurate, the mixing operation is more convenient, and the entire mixing process is carried out in a closed space, so the blood pressure sample will not come into contact with the testing personnel, avoiding the safety threat that the blood sample may pose to the testing personnel, and greatly improving the convenience and safety of dilution and mixing.

[0022] Preferred, refer to Figure 2 and Figure 3 The blood inlet pipe 3, the diluent inlet pipe 4, and the outlet pipe 5 are all located at the bottom of the mixing chamber 1. The turbine 11 is located at the bottom of the rotating shaft 10. This structure ensures that the blood sample and the diluent come into contact with the turbine 11 as soon as they enter the mixing chamber 1, thereby ensuring that the rotating shaft 10 remains in a rotating state throughout the mixing process, thus continuously stirring the mixed liquid and further improving the uniformity of the mixing.

[0023] Preferably, the mixing chamber 1 is also connected to a cleaning pipeline 13, which is equipped with a pure water tank 14 and a control valve 6. This structure allows the plunger pump 2 to pump pure water from the pure water tank 14 into the device through the cleaning pipeline 13 before and after dilution, thereby cleaning each pipeline, avoiding contamination between samples, and further improving the accuracy of analysis and detection.

[0024] Preferably, the cleaning pipeline 13 is connected to the inlet of the plunger pump 2, and the control valve 6 is located between the pure water tank 14 and the plunger pump 2. This structure simplifies the complexity of the device. When the control valve 6 on the cleaning pipeline 13 is closed, the plunger pump 2 can be used to accurately draw blood samples and diluents. When cleaning, the control valve 6 can be opened to perform the cleaning operation of the entire device, making the opening and closing control of the cleaning device more convenient and the cleaning operation smoother and more thorough.

[0025] Preferably, the plunger pump 2 is equipped with a pressure sensor 15. The pressure sensor 15 can be any structure available on the market that can detect the pressure of the pipeline. Specifically, the pressure sensor 15 of the MIK-P300 series from Hangzhou Mico Sensor Technology Co., Ltd. can be used to detect the air pressure of the pipeline, thereby monitoring the overall sealing of the device and ensuring the accuracy of the volume of blood sample and diluent drawn.

[0026] Preferably, the control valve 6 is a pinch valve, which has a simple structure and low cost, and can accurately control the on / off state of the pipeline.

[0027] Working Principle: This invention features a plunger pump 2, a blood inlet pipe 3, a diluent inlet pipe 4, and an outlet pipe 5 connected to a mixing chamber 1. The blood inlet pipe 3 has a sample storage chamber 7, and the diluent inlet pipe 4 has a diluent storage chamber 8. The plunger pump 2 draws a specified volume of blood sample into the sample storage chamber 7 and a specified volume of diluent into the diluent storage chamber 8. Then, the blood sample in the sample storage chamber 7 and the diluent in the diluent storage chamber 8 are drawn into the mixing chamber 1 for mixing. The mixed liquid then enters the detection glass tube 9 through the outlet pipe 5, achieving rapid mixing of the blood sample and diluent. This results in more accurate volume measurement of the blood sample and diluent, significantly improving the convenience of blood dilution and mixing. The system ensures high accuracy and safety, and eliminates the need for personnel to come into contact with the blood sample during the mixing process, significantly improving operational safety and avoiding potential safety threats from blood pressure samples. A rotating shaft 10 is rotatably connected within the mixing chamber 1, and the shaft 10 is equipped with a turbine 11 and multiple stirring rods 12. This structure allows the rotating shaft 10 to rotate under the action of the turbine 11 as the blood sample and diluent enter the mixing chamber 1. This, in turn, causes the multiple stirring rods 12 on the shaft 10 to mix and stir the liquid, resulting in automatic and uniform mixing of the blood sample and diluent without the need for manual intervention. This greatly improves the uniformity of the mixing and further enhances the convenience of blood dilution mixing.

Claims

1. An on-line dilution device for blood analysis comprising a mixing chamber (1), characterized in that: The mixing cavity (1) is provided with a plunger pump (2), a blood inlet pipe (3), a diluent inlet pipe (4) and an outlet pipe (5) in communication, the blood inlet pipe (3), the diluent inlet pipe (4) and the outlet pipe (5) are each provided with a control valve (6), the blood inlet pipe (3) is provided with a sample temporary storage cavity (7), the diluent inlet pipe (4) is provided with a diluent temporary storage cavity (8), the outlet pipe (5) is provided with a detection glass tube (9), the mixing cavity (1) is rotatably connected with a rotating shaft (10), the rotating shaft (10) is provided with a turbine (11), and a plurality of stirring rods (12) are arranged on the rotating shaft (10).

2. The on-line dilution device for blood analysis according to claim 1, wherein: The blood inlet pipe (3), the diluent inlet pipe (4) and the outlet pipe (5) are located at the bottom of the mixing cavity (1), and the turbine (11) is arranged at the bottom of the rotating shaft (10).

3. The on-line dilution device for blood analysis according to claim 1, wherein: The mixing cavity (1) is further provided with a cleaning pipeline (13) in communication, the cleaning pipeline (13) is provided with a pure water tank (14), and the cleaning pipeline (13) is provided with a control valve (6).

4. The on-line dilution apparatus for blood analysis according to claim 3, wherein: The cleaning pipeline (13) is in communication with the water inlet of the plunger pump (2), and the control valve (6) is arranged between the pure water tank (14) and the plunger pump (2).

5. The on-line dilution apparatus for blood analysis according to claim 1, wherein: The plunger pump (2) is provided with a pressure sensor (15).

6. The on-line dilution apparatus for blood analysis according to claim 1, wherein: The control valve (6) is a pinch valve.

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