Disassembling and assembling structure based on tumor fluorescence labeling probe

Abstract

The utility model relates to the field of biomedical engineering, and discloses a dismounting structure based on a tumor fluorescence labeling probe, which comprises a bottom plate and a connecting rod, the front side of the connecting rod is fixedly connected with a support shell, the inside of the support shell is fixedly connected with a cylindrical shell, the inside of the cylindrical shell is slidably connected with a sliding rod, and the sliding rod is fixedly connected with the bottom plate. The outer part of the sliding rod is fixedly connected with an elastic assembly, the outer part of the sliding rod is fixedly connected with a sliding column, the outer part of the sliding column is slidably connected with a fixed cylinder, the inner part of the fixed cylinder is slidably connected with a sphere, and the bottom of the supporting shell is fixedly connected with a probe main body. According to the utility model, the sealing box is in a sealing state when the probe main body is not poked in, so that the interior of the sealing box cannot be polluted, and different fluorescence labeling probes can be quickly replaced according to requirements in the clinical diagnosis and experiment processes, so as to adapt to different tumor types, markers and experiment requirements of people.

Description

Technical Field

[0001] This invention relates to the field of biomedical engineering, and in particular to a disassembly and assembly structure based on tumor fluorescently labeled probes. Background Technology

[0002] Fluorescently labeled probes can be used for targeted imaging of tumor cells, helping doctors detect tumors at an early stage when examining specimens. These probes can enhance the fluorescence signal at the tumor site by binding to specific molecules on the surface of tumor cells, and specifically identify cancer cells and tumor blood vessels in the tumor microenvironment, thereby improving the accuracy and sensitivity of imaging.

[0003] The assembly and disassembly structure of tumor fluorescently labeled probes includes a probe body, a sliding rod, a spring, a sphere, etc. Tumor fluorescently labeled probes are molecular probes used for early diagnosis, localization, and treatment monitoring of tumors. Through specific fluorescent labeling technology, fluorescent molecules and fluorescent dyes are bound to molecules that target tumor cells and tumor tissues, enabling tumor sites to be detected by fluorescence microscopes and imaging systems.

[0004] In existing technologies, some fluorescently labeled probes adopt a fixed design, and each probe replacement requires a complex disassembly process. It requires precise operation and special tools to successfully remove the probe, which results in operators needing a long time to replace the probe, and may even damage the probe and the device itself due to improper operation, affecting the long-term stability and reliability of the device. To address these issues, a disassembly and assembly structure based on tumor fluorescently labeled probes is proposed. Utility Model Content

[0005] The present invention proposes a disassembly and assembly structure based on tumor fluorescently labeled probes, which aims to improve the problem that some existing devices cannot disassemble and assemble probes.

[0006] To achieve the above objectives, the present invention provides the following technical solution:

[0007] The assembly / disassembly structure of the tumor fluorescent labeling probe includes a base plate and a connecting rod. A supporting shell is fixedly connected to the front side of the connecting rod. A cylindrical shell is fixedly connected inside the supporting shell. A sliding rod is slidably connected inside the cylindrical shell. An elastic component is fixedly connected to the outside of the sliding rod. A sliding column is fixedly connected to the outside of the sliding column. A fixed cylinder is slidably connected to the outside of the fixed cylinder. A sphere is slidably connected inside the fixed cylinder. The probe body is fixedly connected to the bottom of the supporting shell. A fluorescent liquid output end is fixedly connected inside the probe body. A sealing box is fixedly connected to the top of the base plate.

[0008] As a further description of the above technical solution:

[0009] The elastic component includes a spring, the outer side of which is fixedly connected to the inside of the cylindrical housing, and the inner side of which is fixedly connected to the outer side of the sliding rod.

[0010] As a further description of the above technical solution:

[0011] A placement platform is fixedly connected to the top of the base plate. A left-right sliding assembly is threadedly connected to the inside of the placement platform. A horizontal sliding block is fixedly connected to the left-right sliding assembly. An up-down sliding assembly is threadedly connected to the inside of the horizontal sliding block. A vertical sliding block is fixedly connected to the up-down sliding assembly.

[0012] As a further description of the above technical solution:

[0013] The left and right sliding assembly includes a lead screw and a connecting block. The external thread of the lead screw is connected to the inside of the placement platform, and the internal thread of the connecting block is connected to the outside of the lead screw.

[0014] As a further description of the above technical solution:

[0015] The up-and-down sliding assembly includes a second lead screw and a second connecting block. The external thread of the second lead screw is connected to the inside of the transverse sliding block, and the internal thread of the second connecting block is connected to the outside of the second lead screw.

[0016] As a further description of the above technical solution:

[0017] A replacement probe placement box is fixedly connected to the top of the base plate. A collection box is fixedly connected to the replacement probe placement box on the side away from the sealing box. A flip cover is rotatably connected to the top of the collection box.

[0018] As a further description of the above technical solution:

[0019] The sliding rod is slidably connected to the outside of the fixed cylinder inside, and the fixed cylinder is fixedly connected to the outside of the probe body inside.

[0020] As a further description of the above technical solution:

[0021] The outer side of the sphere is slidably connected to the inside of the probe body, and the outer side of the sliding column is slidably connected to the inner side of the sphere.

[0022] This utility model has the following beneficial effects:

[0023] 1. In this utility model, pulling the sliding rod upward causes the sliding column outside the sliding rod to slide and squeeze out the sphere inside the fixed cylinder to fix the probe body. If disassembly is required, the operation can be reversed, which saves a lot of operation time. The sealing box is in a sealed state when the probe body is not inserted, which will not cause contamination inside. In clinical diagnosis and experimentation, different fluorescently labeled probes can be quickly replaced as needed to adapt to different tumor types, markers and experimental requirements.

[0024] 2. In this utility model, when replacing and disassembling the probe body, pick up the replacement probe placement box, align the collection box on the side of the replacement probe placement box with the probe body, and collect the used probe body. The flip cover can be opened to take out the probe for disinfection and recycling. Then, align the probe placed on the replacement probe placement box with the sliding rod to replace it. The centralized collection device can help to recycle these probes and reprocess them, reduce material waste, and save costs. Attached Figure Description

[0025] Figure 1 This is a perspective view of the disassembly and assembly structure of the tumor fluorescently labeled probe proposed in this utility model;

[0026] Figure 2 This is a schematic diagram of the placement stage of the disassembly and assembly structure based on the tumor fluorescently labeled probe proposed in this utility model;

[0027] Figure 3 for Figure 2 Enlarged view of point A in the middle;

[0028] Figure 4 This is a schematic diagram of the replacement probe placement box of the disassembly and assembly structure based on tumor fluorescently labeled probes proposed in this utility model;

[0029] Figure 5 for Figure 4 Enlarged view of point B in the middle.

[0030] Legend:

[0031] 1. Base plate; 2. Placement stage; 3. Lead screw one; 4. Connecting block one; 5. Horizontal sliding block; 6. Lead screw two; 7. Connecting block two; 8. Vertical sliding block; 9. Connecting rod; 10. Support shell; 11. Cylindrical shell; 12. Sliding rod; 13. Spring; 14. Sliding column; 15. Fixed cylinder; 16. Sphere; 17. Probe body; 18. Fluorescent liquid output end; 19. Sealing box; 20. Replacement probe placement box; 21. Collection box; 22. Flip cover. Detailed Implementation

[0032] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0033] Reference Figure 1 , Figure 2 , Figure 3 This utility model provides an embodiment of a disassembly and assembly structure based on a tumor fluorescently labeled probe, including a base plate 1, which serves as the supporting foundation for the entire device; a connecting rod 9, which connects a supporting shell 10 and a vertical sliding block 8; the supporting shell 10 is fixedly connected to the front side of the connecting rod 9; a cylindrical shell 11 is installed inside the supporting shell 10; both the supporting shell 10 and the connecting rod 9 provide support; the cylindrical shell 11 is fixedly connected inside the supporting shell 10, and the cylindrical shell 11 accommodates an internal sliding rod 12 for sliding within it; the internal sliding connection of the cylindrical shell 11... A sliding rod 12 is connected to the outside of the cylindrical shell 11. The sliding rod 12 slides inside the cylindrical shell 11, causing the externally connected sliding column 14 to slide together. An elastic component is fixedly connected to the outside of the sliding rod 12. The elastic component includes a spring 13. The outside of the spring 13 is fixedly connected to the inside of the cylindrical shell 11, and the inside of the spring 13 is fixedly connected to the outside of the sliding rod 12. The function of the spring 13 is to provide a certain elastic force to drive the sliding rod 12 to reset. The external of the sliding rod 12 is fixedly connected to the sliding column 14. The sliding column 14 slides up and down under the action of the sliding rod 12 to fix and disassemble the probe body 17.

[0034] A fixed cylinder 15 is slidably connected to the outside of the sliding column 14. The fixed cylinder 15 is fixedly connected to the top cylindrical outer shell 11, both accommodating the sliding rod 12 and the sliding column 14 to slide inside. Spherical spheres 16 slide on both sides inside the fixed cylinder 15. The spheres 16 are slidably connected inside the fixed cylinder 15. Under the sliding pressure of the sliding column 14, the spheres 16 slide outwards and inwards to fix and disassemble the probe body 17. The probe body 17 is fixedly connected to the bottom of the supporting outer shell 10. The probe body 17 is the core component of the device, responsible for the tumor fluorescence labeling operation. A fluorescent liquid infusion is fixedly connected inside the probe body 17. The fluorescent liquid output end 18 is responsible for delivering the fluorescent liquid and labeled liquid into the probe body 17 and then into the corresponding sample. The fluorescent liquid output end 18 is fixedly connected inside the probe body 17. The fluorescent liquid output end 18 is responsible for delivering the labeled fluorescent liquid into the probe body 17 for the detection of tumor tissue. A sealing box 19 is fixedly connected to the top of the base plate 1. The sealing box 19 is made of rubber. When the probe body 17 is inserted into the interior, it wraps around the probe body 17 to seal it. When the probe is not inserted, it is in a sealed state to protect the internal specimen from external contamination and damage and to prevent dust and moisture from entering.

[0035] Reference Figure 2 , Figure 4 , Figure 5 A placement platform 2 is fixedly connected to the top of the base plate 1. The placement platform 2 is used to place the vertical sliding assembly and the horizontal sliding assembly. The horizontal sliding assembly is internally threaded to the placement platform 2. The horizontal sliding assembly includes a lead screw 3 and a connecting block 4. The lead screw 3 is externally threaded to the inside of the placement platform 2. The lead screw 3 drives the externally connected connecting block 4 to slide left and right on its exterior. The internal thread of the connecting block 4 is externally threaded to the lead screw 3. The left and right sliding of the connecting block 4, under the left and right rotation of the lead screw 3, drives the connecting probe on the front side of the front horizontal sliding block 5 to adjust left and right. The horizontal sliding assembly is fixedly... A horizontal sliding block 5 is fixedly connected to the probe body 17. The horizontal sliding block 5 connects the left and right sliding components and the probe body 17. The internal thread of the horizontal sliding block 5 is connected to the vertical sliding component. The vertical sliding component is used to drive the probe body 17 connected to the front side to adjust its vertical height. The vertical sliding component includes a lead screw 6 and a connecting block 7. The external thread of the lead screw 6 is connected to the inside of the horizontal sliding block 5. Tightening the lead screw 6 drives the probe body 17 in front of the external connecting block 7 to slide up and down. The internal thread of the connecting block 7 is connected to the outside of the lead screw 6. The connecting block 7 slides up and down under the rotation of the lead screw.

[0036] The vertical sliding assembly is fixedly connected to a vertical sliding block 8. The vertical sliding block 8 outputs the power of the screw 6 to drive the probe body 17 to slide up and down to mark the specimen. Manually adjusting the angle of the probe body 17 can easily cause shaking and misoperation. The left and right sliding assembly and the vertical sliding assembly can stably adjust the probe body 17. The top of the base plate 1 is fixedly connected to a replacement probe placement box 20. The replacement probe placement box 20 is used to store and replace probes. The replacement probe placement box 20 is fixedly connected to a collection box 21 on the side away from the sealing box 19. The collection box 21 is used to collect the used probe body 17 that needs to be disinfected. The top of the collection box 21 is rotatably connected to a flip cover 22. The flip cover 22 is used to open the collection box 21, take out the used probe inside, disinfect it, and reuse it. The outside of the sliding rod 12 is slidably connected to the inside of the fixed cylinder 15. The outside of the fixed cylinder 15 is fixedly connected to the inside of the probe body 17. The outside of the sphere 16 is slidably connected to the inside of the probe body 17. The outside of the sliding column 14 is slidably connected to the inside of the sphere 16.

[0037] Working principle: The base plate 1 is placed on a stable surface as the supporting foundation of the entire device. The supporting shell 10 is connected to the vertical sliding block 8 through the connecting rod 9 to form a supporting structure. The operator can control the inward and outward sliding of the sphere 16 inside the fixed cylinder 15 by adjusting the up and down movement of the sliding column 14 outside the sliding rod 12, thereby realizing the fixing and disassembly of the probe body 17. The sliding rod 12 is externally connected to a spring 13. The spring 13 inside the cylindrical shell 11 provides elastic force to drive the sliding rod 12 to reset, ensuring that the device returns to its initial state after each installation and disassembly. When performing tumor fluorescent labeling, the probe body 17 delivers the fluorescent liquid to the sample through the fluorescent liquid output end 18. The rubber material of the sealing box 19 ensures the sealing around the probe body 17 to prevent external contamination. The operator can adjust the left and right and up and down positions of the probe body 17 through the left and right sliding components and the up and down sliding components in the placement platform 2 to ensure that the probe is accurately positioned on the sample. The left and right sliding components and the up and down sliding components drive the horizontal sliding block 5 and the vertical sliding block 8 connected to the top of the connecting block 4 and the front side of the connecting block 7 by rotating the lead screw 1 3 and the lead screw 2 6, respectively realizing the left and right and up and down movement of the probe body 17, providing a stable adjustment method and reducing shaking and misoperation caused by manual adjustment.

[0038] After use, when disassembling the probe, place the collection box 21 at the bottom and pull down the sliding rod 12 to disassemble and collect it. When replacing the new probe body 17, align the replacement probe placement box 20 with the sphere 16 and pull up the sliding rod 12 to fix the new probe. The used probe will be collected in the collection box 21 when replacing the probe body 17, and will be used again after cleaning and disinfection. The flip cover 22 makes it easy for operators to take out the used probe, ensuring the hygiene and safety of the equipment.

[0039] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A dismountable structure based on tumor fluorescent labeling probe, comprising a base plate (1), a connecting rod (9), characterized in that: The front side of the connecting rod (9) is fixedly connected with a support shell (10), the inside of the support shell (10) is fixedly connected with a cylindrical shell (11), the inside of the cylindrical shell (11) is slidably connected with a sliding rod (12), the outside of the sliding rod (12) is fixedly connected with an elastic component, the outside of the sliding rod (12) is fixedly connected with a sliding column (14), the outside of the sliding column (14) is slidably connected with a fixed cylinder (15), the inside of the fixed cylinder (15) is slidably connected with a spherical body (16), the bottom of the support shell (10) is fixedly connected with a probe main body (17), the inside of the probe main body (17) is fixedly connected with a fluorescent liquid output end (18), the top of the bottom plate (1) is fixedly connected with a sealed box (19).

2. The tumor fluorescence labeling probe based disassembly structure according to claim 1, characterized in that: The elastic component comprises a spring (13), the outside of the spring (13) is fixedly connected in the inside of the cylindrical shell (11), and the inside of the spring (13) is fixedly connected to the outside of the sliding rod (12).

3. The tumor fluorescence labeling probe based disassembly structure according to claim 1, characterized in that: The top of the bottom plate (1) is fixedly connected with a placing table (2), the inside of the placing table (2) is threadedly connected with a left-right sliding assembly, the left-right sliding assembly is fixedly connected with a transverse sliding block (5), the inside of the transverse sliding block (5) is threadedly connected with an up-down sliding assembly, and the up-down sliding assembly is fixedly connected with a vertical sliding block (8).

4. The tumor fluorescence labeling probe based disassembly structure according to claim 3, characterized in that: The left-right sliding assembly comprises a lead screw (3) and a connecting block (4), the outside of the lead screw (3) is threadedly connected in the inside of the placing table (2), and the inside of the connecting block (4) is threadedly connected to the outside of the lead screw (3).

5. The tumor fluorescence labeling probe based disassembly structure according to claim 3, characterized in that: The up-down sliding assembly comprises a lead screw (6) and a connecting block (7), the outside of the lead screw (6) is threadedly connected in the inside of the transverse sliding block (5), and the inside of the connecting block (7) is threadedly connected to the outside of the lead screw (6).

6. The tumor fluorescence labeling probe based disassembly structure according to claim 1, characterized in that: The top of the bottom plate (1) is fixedly connected with a probe replacement placing box (20), the probe replacement placing box (20) is fixedly connected with a collection box (21) away from the sealed box (19), and the top of the collection box (21) is rotatably connected with a flip cover (22).

7. The tumor fluorescence labeling probe based disassembly structure according to claim 1, characterized in that: The outside of the sliding rod (12) is slidably connected in the inside of the fixed cylinder (15), and the outside of the fixed cylinder (15) is fixedly connected in the inside of the probe main body (17).

8. The tumor fluorescence labeling probe based disassembly structure according to claim 1, characterized in that: The outside of the spherical body (16) is slidably connected in the inside of the probe main body (17), and the outside of the sliding column (14) is slidably connected to the inside of the spherical body (16).

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