Chromatographic device

By using a lower plug connected to the column tube drive mechanism in the chromatography apparatus, the problem of easy plug damage is solved, a convenient and airtight connection is achieved, and maintenance costs are reduced.

CN223841838UActive Publication Date: 2026-01-27TRUKING INGENUITY BIOTECHNOLOGY (CHANGSHA) CO LTD
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Patent Information

Application Number
CN202520021439.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-03
Publication Date
2026-01-27
Estimated Expiration
2035-01-03

AI Technical Summary

Technical Problem

In existing chromatographic separation equipment, the screw connection between the plug and the column tube is prone to damage, resulting in high maintenance costs and poor sealing.

Method used

The lower plug is connected to or separated from the column tube via a second drive mechanism. The lower plug is driven by a pneumatic hydraulic pump and a hydraulic cylinder. Combined with a limit ring and a sealing ring, a connection method with good sealing performance and convenience is achieved.

Benefits of technology

It reduces maintenance costs, avoids contamination of the inside of the column tube due to damage to screw holes, and improves sealing performance and ease of operation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a chromatography device which comprises a support, a column tube, an upper chock plug and a lower chock plug are arranged on the support, the upper chock plug is connected with a first driving mechanism used for enabling the upper chock plug to ascend and descend in the column tube, the lower chock plug is connected with a second driving mechanism, and the second driving mechanism is used for driving the lower chock plug to be in butt joint with or separated from the column tube. The chromatographic device has the advantages that the lower chock plug is convenient to butt and separate, the maintenance cost is reduced, the sealing performance is good, and the like.
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Description

Technical Field

[0001] This utility model relates to the field of food and pharmaceutical packaging machinery and equipment technology, specifically to a chromatography device. Background Technology

[0002] Existing chromatographic separation equipment generally includes a column, an upper stopper inside the column, and a plug at the bottom of the column, secured by screws. During operation, material is added into the space between the upper stopper and the plug within the column. The upper stopper is then pressed down to solidify the material between the upper stopper and the plug. Finally, the plug is removed to retrieve the solidified material. In practical applications, due to the varying production process requirements of different products, issues such as high levels of impurities in raw materials and material contamination are frequently encountered, necessitating frequent disassembly and reassembly of the plug for cleaning or replacement. However, since the plug is connected to the column with screws, frequent disassembly and reassembly easily damages the screw holes and screws, increasing maintenance costs and potentially affecting the plug's sealing performance and contaminating the internal environment of the column. Utility Model Content

[0003] The technical problem to be solved by this utility model is to overcome the shortcomings of the prior art and provide a chromatography device that is easy to connect and separate the lower stopper head, reduces maintenance costs, and has good sealing performance.

[0004] To solve the above-mentioned technical problems, the present invention adopts the following technical solution:

[0005] A chromatography apparatus includes a support, on which a column tube, an upper stopper, and a lower stopper are mounted. The upper stopper is connected to a first drive mechanism for moving the upper stopper up and down within the column tube, and the lower stopper is connected to a second drive mechanism for driving the lower stopper to engage or disengage with the column tube.

[0006] As a further improvement to the above technical solution:

[0007] The maximum pressure resistance of the second drive mechanism is greater than that of the first drive mechanism.

[0008] The second drive mechanism includes a pneumatic hydraulic pump and a hydraulic cylinder. The hydraulic cylinder is equipped with a drive rod, which is connected to the lower plug.

[0009] The outer periphery of the column tube is provided with a limiting ring, the limiting ring is supported on the bracket, and a pressure ring is pressed on the bracket and fixed on the bracket.

[0010] The outer periphery of the column tube is provided with an annular groove, and the limiting ring is formed by two arc-shaped hoops fixedly connected together, with the two arc-shaped hoops held in the annular groove.

[0011] The outer periphery of the column tube is provided with a limiting ring, which is fixedly supported on the bracket.

[0012] The bottom of the column tube is provided with a tapered opening for sealing with the lower plug, and a sealing ring is provided on the periphery of the lower plug.

[0013] The support is provided with a translation mechanism, and the second drive mechanism is located on the translation mechanism.

[0014] The translation mechanism includes a translation seat that is translatably positioned and a translation drive for translating the translation seat, wherein the second drive mechanism is disposed on the translation seat.

[0015] The first driving mechanism includes a fixed base and a telescopic driving member. The fixed base is mounted on a bracket, and the telescopic driving member is mounted on the fixed base. The upper plug is connected to the driving end of the telescopic driving member.

[0016] Compared with the prior art, the advantages of this utility model are:

[0017] In this chromatographic apparatus, the lower stopper head is driven by a second driving mechanism to dock with or separate from the bottom end of the column tube 1. In contrast, the lower stopper head is connected to the column tube by screws. The docking and disassembly of the lower stopper head is convenient, eliminating the need for frequent disassembly and assembly of screws. It is unaffected by damage to screw holes and screws, thus avoiding contamination of the internal environment of the column tube due to damage to screw holes and screws, reducing maintenance costs. Furthermore, the lower stopper head docks with the column tube under the driving force of the second driving mechanism, ensuring good sealing. Attached Figure Description

[0018] Figure 1 This is a three-dimensional structural diagram of the chromatography apparatus of this utility model.

[0019] Figure 2 This is a cross-sectional structural schematic diagram of the chromatographic apparatus of this utility model.

[0020] Figure 3 yes Figure 2 A magnified structural diagram of point A in the middle.

[0021] Figure 4 yes Figure 2 A magnified structural diagram at point B in the middle.

[0022] The labels in the diagram represent:

[0023] 1. Column tube; 11. Limiting ring; 12. Pressure ring; 13. Ring groove; 2. Upper plug; 3. First drive mechanism; 31. Fixed seat; 32. Telescopic drive component; 4. Lower plug; 41. Sealing ring; 5. Bracket; 6. Second drive mechanism; 61. Pneumatic hydraulic pump; 62. Hydraulic cylinder; 621. Drive rod; 7. Conical opening; 8. Translation mechanism; 81. Translation seat; 82. Translation drive component. Detailed Implementation

[0024] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0025] In the description of this utility model, it should be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0026] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0027] In this utility model, unless otherwise explicitly specified and limited, the terms "assembly," "connection," "joining," and "fixing" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0028] Figures 1 to 4 An embodiment of the chromatography apparatus of this utility model is shown. The chromatography apparatus of this embodiment includes a support 5, on which a column tube 1, an upper stopper 2 and a lower stopper 4 are provided. The upper stopper 2 is connected to a first drive mechanism 3 for moving the upper stopper 2 up and down inside the column tube 1, and the lower stopper 4 is connected to a second drive mechanism 6 for driving the lower stopper 4 to engage or disengage with the column tube 1.

[0029] In this chromatographic apparatus, the lower stopper 4 is driven by the second driving mechanism 6 to dock with or separate from the bottom end of the column tube 1. It is connected to the column tube 1 by screws. The docking and disassembly of the lower stopper 4 is convenient, without the need for frequent disassembly and assembly of screws. It is not affected by damage to screw holes or screws, thus avoiding contamination of the internal environment of the column tube 1 due to damage to screw holes or screws, reducing maintenance costs. Furthermore, the lower stopper 4 docks with the column tube 1 under the driving force of the second driving mechanism 6, ensuring good sealing.

[0030] Furthermore, in this embodiment, the maximum pressure resistance of the second drive mechanism 6 is greater than that of the first drive mechanism 3. That is, during the pressing process, the downward pressure exerted by the first drive mechanism 3 on the upper stopper 2 is less than the upward thrust exerted by the second drive mechanism 6 on the upper stopper 2, preventing the lower stopper 4 from being pushed open during the pressing process.

[0031] Furthermore, in this embodiment, the second drive mechanism 6 includes a pneumatic hydraulic pump 61 and a hydraulic cylinder 62. The hydraulic cylinder 62 is equipped with a drive rod 621, which is connected to the lower plug head 4. When the pneumatic hydraulic pump 61 operates, it causes the drive rod 621 of the hydraulic cylinder 62 to extend and retract, thereby driving the lower plug head 4 to rise and fall to dock with and separate from the bottom of the column tube 1.

[0032] Generally, the hydraulic cylinder 62 needs to withstand a pressure of 25 MPa. Therefore, during the pressing process, the weight of the material between the upper stopper 2 and the lower stopper 4 can be ignored relative to the pressure resistance of the hydraulic cylinder 62.

[0033] During the pressing process, the material between the upper stopper 2 and the lower stopper 4 is generally kept in dynamic balance under the downward pressure of the upper stopper 2 and the upward thrust of the lower stopper 4. In this way, the support 5 is not subjected to additional pressing force, but only bears the weight of the device itself.

[0034] Furthermore, such as Figure 4 As shown, in this embodiment, a limiting ring 11 is provided on the outer periphery of the column tube 1. The limiting ring 11 is supported on the bracket 5, and a pressure ring 12 is pressed on the bracket 5 and fixed on the bracket 5. The limiting ring 11 is provided on the outer periphery of the column tube 1 and is pressed and fixed on the bracket 5 by the pressure ring 12, which makes it easy to assemble and disassemble.

[0035] Furthermore, in this embodiment, the outer periphery of the column tube 1 is provided with an annular groove 13, and the limiting ring 11 is formed by two arc-shaped hoops fixedly connected together, with the two arc-shaped hoops fitting within the annular groove 13. The limiting ring 11 is formed by two arc-shaped hoops fixedly connected together, such as by bolts, which facilitates replacement. In other embodiments, the outer periphery of the column tube 1 is provided with a limiting ring 11, and the limiting ring 11 is fixedly supported on the bracket 5. That is, the column tube 1 can be directly fixed to the bracket 5 by the limiting ring 11, or the limiting ring 11 can be fixed to the bracket 5 by screws.

[0036] Furthermore, such as Figure 3 As shown, in this embodiment, the bottom of the column tube 1 is provided with a conical opening 7 for sealing with the lower plug head 4, and a sealing ring 41 is provided on the periphery of the lower plug head 4. The conical opening 7 is conical, which facilitates docking and separation with the lower plug head 4. Correspondingly, the periphery of the lower plug head 4 can also be set to be conical, which facilitates mating with the conical opening 7. The sealing ring 41 on the periphery of the lower plug head 4 improves the sealing performance when mating with the conical opening 7.

[0037] Furthermore, such as Figure 2 As shown, in this embodiment, the support 5 is provided with a translation mechanism 8, and the second drive mechanism 6 is provided on the translation mechanism 8. In this way, when feeding material, the second drive mechanism 6 drives the lower plug 4 to descend and move out of the column tube 1, and then drives the translation mechanism 8 to move, opening up the space below the translation mechanism 8, so that the upper plug 2 can press down to discharge material.

[0038] Further, in this embodiment, the translation mechanism 8 includes a translation seat 81 that is translatably positioned and a translation drive 82 for translating the translation seat 81. The second drive mechanism 6 is disposed on the translation seat 81. The translation drive 82 drives the translation seat 81 to translate, thereby driving the second drive mechanism 6 and the lower plug head 4 to translate. Preferably, the translation drive 82 is a translation cylinder. More preferably, the bottom of the translation seat 81 is provided with a moving wheel, which is supported on the ground.

[0039] Furthermore, in this embodiment, the first driving mechanism 3 includes a fixed base 31 and a telescopic driving member 32. The fixed base 31 is disposed on the bracket 5, and the telescopic driving member 32 is disposed on the fixed base 31. The upper plug 2 is connected to the driving end of the telescopic driving member 32. The telescopic driving member 32 drives the upper plug 2 to move up and down. Preferably, the telescopic driving member 32 is a hydraulic telescopic cylinder.

[0040] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make many possible variations and modifications to the present invention, or modify it into equivalent embodiments, without departing from the scope of the present invention. Therefore, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention, without departing from the content of the present invention, should fall within the protection scope of the present invention.

Claims

1. A chromatographic apparatus, characterized in that: Includes a bracket (5), on which a column tube (1), an upper plug (2) and a lower plug (4) are provided. The upper plug (2) is connected to a first drive mechanism (3) for raising and lowering the upper plug (2) inside the column tube (1). The lower plug (4) is connected to a second drive mechanism (6), which is used to drive the lower plug (4) to dock or separate from the column tube (1).

2. The chromatographic apparatus according to claim 1, characterized in that: The maximum pressure resistance of the second drive mechanism (6) is greater than the maximum pressure resistance of the first drive mechanism (3).

3. The chromatographic apparatus according to claim 1, characterized in that: The second drive mechanism (6) includes a pneumatic hydraulic pump (61) and a hydraulic cylinder (62). The hydraulic cylinder (62) is provided with a drive rod (621), which is connected to the lower plug (4).

4. The chromatographic apparatus according to claim 1, characterized in that: The outer periphery of the column tube (1) is provided with a limiting ring (11), the limiting ring (11) is supported on the bracket (5), and a pressure ring (12) is pressed on the bracket (5), the pressure ring (12) is fixed on the bracket (5).

5. The chromatographic apparatus according to claim 4, characterized in that: The outer periphery of the column tube (1) is provided with an annular groove (13), and the limiting ring (11) is formed by two arc-shaped hoops fixedly connected, with the two arc-shaped hoops held in the annular groove (13).

6. The chromatographic apparatus according to claim 1, characterized in that: The outer periphery of the column tube (1) is provided with a limiting ring (11), which is fixedly supported on the bracket (5).

7. The chromatographic apparatus according to any one of claims 1 to 6, characterized in that: The bottom of the column tube (1) is provided with a tapered opening (7) for sealing with the lower plug (4), and a sealing ring (41) is provided on the periphery of the lower plug (4).

8. The chromatographic apparatus according to any one of claims 1 to 6, characterized in that: The bracket (5) is provided with a translation mechanism (8), and the second drive mechanism (6) is provided on the translation mechanism (8).

9. The chromatographic apparatus according to claim 8, characterized in that: The translation mechanism (8) includes a translation seat (81) for translation and a translation drive (82) for translating the translation seat (81), wherein the second drive mechanism (6) is disposed on the translation seat (81).

10. The chromatographic apparatus according to any one of claims 1 to 6, characterized in that: The first driving mechanism (3) includes a fixed seat (31) and a telescopic driving member (32). The fixed seat (31) is mounted on the bracket (5), and the telescopic driving member (32) is mounted on the fixed seat (31). The upper plug (2) is connected to the driving end of the telescopic driving member (32).