NK cell amplification kit

Abstract

The utility model relates to the technical field of kits, in particular to an NK (Natural Killer) cell amplification kit, which comprises a kit body provided with a kit cover, and further comprises a partition plate arranged in the kit body and provided with a plurality of limiting holes for placing reagent bottles, and an amplification device arranged in the kit body, the side plate is mounted at the bottom end of the partition plate in a sliding manner; and the fixing block is fixedly installed at the bottom end of the partition plate, a sliding rod is installed in the fixing block in a sliding mode, and a limiting plate is fixedly installed on the sliding rod. When a reagent bottle is taken out, the two sides of the reagent box can be pressed, the side plates on the two sides are squeezed to move, the long rods are driven to move along with movement of the side plates, the long rods drive the abutting rods to be inserted into the inclined blocks in the sliding rods, the inclined blocks are squeezed to drive the sliding rods to move, and therefore the limiting plates are made to be far away from the reagent bottle; and therefore, the reagent bottle can be conveniently taken out.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of reagent box, especially NK cell expansion reagent box. BACKGROUND

[0002] NK cell, natural killer cell, is an important cell type in the human immune system. They belong to a kind of lymphocyte, mainly exist in blood, lymphoid tissue and certain organs. The main function of NK cell is to recognize and kill virus infected cells and some cancer cells. Unlike T cells, which need to recognize specific antigens in advance, NK cells can directly recognize and attack abnormal cells, so they are called "natural" killers.

[0003] And various NK cell activation special culture bottle, and various reagent bottle usually need to utilize reagent box to store transportation, existing part reagent box when storing reagent bottle, often is directly put reagent bottle into it, such as the disclosure no. CN205741066U, it includes box cover, box body and fixed seat, is provided with a plurality of reagent bottle insertion slots on the fixed seat, each reagent bottle is inserted in the corresponding reagent bottle insertion slot, can satisfy the need of various NK cell in vitro expansion experiment, the shockproof component sponge inside the box cover can effectively avoid the collision phenomenon of reagent bottle and box cover, it although solves the function of avoiding collision and limiting, but including the other part product in above patent, when limiting, utilize the sponge or spring to extrude limit, although it has played the better anti-shake and limiting function, but when using, if reagent bottle is taken out, because the tightness of extrusion, at this time, the staff needs to press reagent box with one hand, and takes out reagent bottle with one hand, and when taking out reagent bottle, because the friction is relatively large, it is easy to bring the partition of reagent box inside skew, and it is also easy to drive other reagent bottle deviation, to cause inconvenient to take out. UTILITARIAN CONTENT

[0004] The utility model aims at providing a kind of NK cell expansion reagent box, solve the problem that reagent bottle is not easy to take out when taking out reagent bottle due to the tight extrusion of sponge or spring.

[0005] To achieve the above object, the utility model adopts the following technical scheme:

[0006] The application relates to an NK cell expansion kit, which comprises a kit body, a box cover mounted on the kit body, a partition plate arranged in the kit body and provided with a plurality of limiting holes for placing reagent bottles, a side plate slidingly mounted at the bottom end of the partition plate, a fixing block fixedly mounted at the bottom end of the partition plate, a sliding rod slidingly mounted in the fixing block, a limiting plate fixedly mounted on the sliding rod, a limiting spring fixedly mounted between the limiting plate and the fixing block, a long rod fixedly mounted on the side plate, an abutting rod fixedly mounted on the long rod, and a through hole formed in the surface of the sliding rod and provided with an inclined block fixedly mounted on the inner wall of the through hole.

[0007] Preferably, the end, away from the sliding rod, of the limiting plate is provided with a chamfer.

[0008] Preferably, the limiting plate is arranged in an arc shape and is provided with a rubber pad on the surface.

[0009] Preferably, the abutting rod is in a concave shape.

[0010] Preferably, the end, away from the side plate, of the long rod is fixedly mounted with a square plate, the bottom end of the partition plate is fixedly mounted with a fixed plate, and a return spring is fixedly mounted between the square plate and the fixed plate.

[0011] Preferably, the kit further comprises a sliding plate arranged on the inner wall of the kit, the side wall of the partition plate is provided with a groove matched with the size of the sliding plate, the bottom end of the sliding plate is fixedly mounted with a bottom plate, the bottom end of the bottom plate is fixedly mounted with a connecting spring, the two ends of the bottom plate are fixedly mounted with inserting rods, a lengthening plate is fixedly mounted on the side plate, and an inserting hole is formed in the lengthening plate.

[0012] The application has at least the following beneficial effects:

[0013] When the reagent bottle is taken out, the two sides of the kit can be pressed, at the moment, the side plates on the two sides are pressed to move, the movement of the side plates drives the long rod to move, at the moment, the long rod drives the abutting rod to be inserted into the inclined block in the sliding rod, the inclined block is pressed to drive the sliding rod to move, the limiting plate is moved away from the reagent bottle, the pressing and limiting of the reagent bottle are released, and the reagent bottle is conveniently taken out. BRIEF DESCRIPTION OF DRAWINGS

[0014] In order to more clearly illustrate the technical scheme of the application, the following will briefly introduce the drawings needed in the embodiment description. Obviously, the drawings in the following description are some embodiments of the application, and other drawings can be obtained by those skilled in the art without creative labor.

[0015] Figure 1 It is a three-dimensional structure schematic view of the application.

[0016] Figure 2 For the utility model Figure 1 Part structure schematic view of bottom side;

[0017] Figure 3 For the utility model Figure 2 Part structure schematic view of bottom side;

[0018] Figure 4 For the utility part structure schematic view of sliding plate of the utility model;

[0019] Figure 5 For the utility part structure schematic view of limiting plate of the utility model;

[0020] Figure 6 For the utility model Figure 5 Structure schematic view of A place.

[0021] In the figure: 1, reagent box body;2, box cover;3, partition plate;41, sliding plate;42, bottom plate;43, plug rod;44, extension plate;45, convex plate;51, side plate;52, long rod;53, fixed block;54, sliding rod;55, inclined block;56, abutment rod;57, limiting plate;58, square plate;59, fixed plate. Specific implementation

[0022] Referring to Figures 1-6 As shown, the application provides a kind of technical scheme: a kind of NK cell expansion kit, including reagent box body 1, reagent box body 1 is installed with box cover 2, still include: partition plate 3, it is set in reagent box body 1, and a plurality of limiting holes are set in partition plate 3 to place reagent bottle;Side plate 51, it is slidably installed in the bottom end of partition plate 3;Wherein side plate 51 can also be used to support partition plate 3;Fixed block 53, it is fixedly installed in the bottom end of partition plate 3, sliding rod 54 is slidably installed in the inside of fixed block 53, limiting plate 57 is fixedly installed on sliding rod 54, and limiting plate 57 and fixed block 53 between fixedly installed limiting spring;Wherein limiting spring extrudes limiting plate 57, so that limiting plate 57 is extruded and positioned to the reagent bottle placed in limiting hole;

[0023] Long rod 52, it is fixedly installed on side plate 51, long rod 52 is fixedly installed with abutment rod 56, the surface of sliding rod 54 is provided with through hole, and the inner wall of through hole is fixedly installed with inclined block 55;

[0024] After the separator 3 is placed inside the reagent kit, it is supported by the side plate 51. The size of the separator 3 is adapted to the inner wall size of the reagent kit, ensuring that the separator 3 will not shift. The side plate 51 also supports the separator 3. The reagent bottle can be placed directly into the limiting hole of the separator 3. At this time, the limiting spring on the fixing block 53 will push the limiting plate 57 to squeeze the reagent bottle, thus limiting its movement and preventing it from shaking or colliding. When it is necessary to remove the reagent bottle, pressing the reagent kit body 1 will prevent it from being removed. Since the reagent kit body 1 is usually a cardboard box or... When using other plastic boxes, the reagent kit body 1 will have a certain elasticity and can be pressed. At this time, the side plate 51 will be pressed down. As the side plate 51 is pressed down and moves, the long rod 52 on the bottom of the side plate 51 will move. At this time, the long rod 52 will drive the abutment rod 56 to move, and the abutment rod 56 will abut against the inclined side of the inclined block 55. At this time, the inclined side will be pressed down and drive the slide rod 54 to move, thereby making the limiting plate 57 move away from the reagent bottle, thereby releasing the limitation on the reagent bottle, making it convenient for a single reagent bottle to be taken out, and the reagent kit and the separator plate 3 will not be moved when it is taken out.

[0025] Specifically, the end of the limiting plate 57 away from the slide bar 54 is provided with a chamfer;

[0026] This causes the reagent bottle to press against the chamfer above the limiting plate 57 when it is lowered from the limiting hole, thus moving the two limiting plates 57 apart to facilitate the lowering of the reagent bottle.

[0027] Specifically, the limiting plate 57 is arc-shaped; the arc shape allows for better fit to the reagent bottle, and the surface of the limiting plate 57 is provided with a rubber pad; the rubber pad increases friction to better limit the reagent bottle, and also has a certain degree of elasticity to protect the reagent bottle.

[0028] Specifically, the abutment rod 56 is concave in shape;

[0029] The abutment rod 56 is concave, which allows it to simultaneously abut against the inclined blocks 55 inside the two slide rods 54 when it moves, thus facilitating the simultaneous opening of the two limiting plates 57.

[0030] Specifically, a square plate 58 is fixedly installed at the end of the long rod 52 away from the side plate 51, a fixing plate 59 is fixedly installed at the bottom end of the partition plate 3, and a return spring is fixedly installed between the square plate 58 and the fixing plate 59.

[0031] When the side plate 51 is pressed, the side plate 51 will drive the long rod 52 and the square plate 58 to move, thereby squeezing the return spring. At this time, the return spring will be compressed until the side plate 51 is released. Then the return spring will push the side plate 51 to return to its original position.

[0032] Specifically, it also includes a slide plate 41, which is set on the inner wall of the reagent kit, and the side wall of the partition plate 3 is provided with a groove that matches the size of the slide plate 41. A base plate 42 is fixedly installed at the bottom end of the slide plate 41, a connecting spring is fixedly installed at the bottom end of the base plate 42, and plug rods 43 are fixedly installed at both ends of the base plate 42. An extension plate 44 is fixedly installed on the side plate 51, and an insertion hole is provided on the extension plate 44.

[0033] When the lid 2 is closed, the protrusion on the lid 2 will press the slide plate 41, causing the slide plate 41 to move downwards. As the slide plate 41 moves downwards, it will drive the base plate 42 and the insert rods 43 on both sides of the base plate 42 to move downwards. At this time, the insert rods 43 will be inserted into the insertion holes, thereby restricting the sliding of the two side plates 51 and preventing the side plates 51 from being squeezed and moving during transportation. When the lid 2 is opened, the connecting spring will bounce upwards, thereby pushing the slide plate 41 to rise. At this time, the slide plate 41 will drive the insert rods 43 to move out of the insertion holes, and the side plates 51 can move freely.

[0034] A protruding plate 45 is fixedly installed on the inner wall of the reagent kit body 1; the protruding plate 45 is used to abut against the connecting spring.

[0035] The inner bottom wall of the reagent kit body 1 can also be equipped with a tray, and the tray is provided with several sponge pads. The sponge pads on the tray can support and protect the bottom of the reagent bottle, and the side plate 51 can abut against the tray for support, and there are no sponge pads to obstruct its movement trajectory.

[0036] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. An NK cell expansion kit comprising a kit body (1) on which a lid (2) is mounted, characterized in that, Also include: The partition plate (3) is arranged in the kit body (1), and a plurality of limiting holes are arranged on the partition plate (3) to place reagent bottles; The side plate (51) is slidingly installed at the bottom end of the partition plate (3); The fixed block (53) is fixedly installed at the bottom end of the partition plate (3), the inner part of the fixed block (53) is slidingly installed with the slide rod (54), the slide rod (54) is fixedly installed with the limiting plate (57), and the limiting plate (57) and the fixed block (53) are fixedly installed with the limiting spring; The long rod (52) is fixedly installed on the side plate (51), the long rod (52) is fixedly installed with the abutting rod (56), the surface of the slide rod (54) is provided with a through hole, and the inner wall of the through hole is fixedly installed with the inclined block (55).

2. The NK cell expansion kit of claim 1, wherein, The end of the limiting plate (57) away from the slide rod (54) is provided with a chamfer.

3. The NK cell expansion kit of claim 1, wherein, The limiting plate (57) is arranged in an arc shape, and the surface of the limiting plate (57) is provided with a rubber pad.

4. The NK cell expansion kit of claim 1, wherein, The abutting rod (56) is concave.

5. The NK cell expansion kit of claim 1, wherein, The end of the long rod (52) away from the side plate (51) is fixedly installed with the square plate (58), the bottom end of the partition plate (3) is fixedly installed with the fixed plate (59), and the square plate (58) and the fixed plate (59) are fixedly installed with the reset spring.

6. The NK cell expansion kit of claim 1, wherein, The slide plate (41) is arranged on the inner wall of the kit, the side wall of the partition plate (3) is provided with a groove matched with the size of the slide plate (41), the bottom end of the slide plate (41) is fixedly installed with the bottom plate (42), the bottom end of the bottom plate (42) is fixedly installed with the connecting spring, the two ends of the bottom plate (42) are fixedly installed with the insertion rod (43), the side plate (51) is fixedly installed with the extension plate (44), and the extension plate (44) is provided with an insertion hole.

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