Multi-modal immunohistochemical kit

Abstract

The utility model relates to the technical field of medical instruments, and particularly discloses a multi-modal immunohistochemical kit which comprises a storage box, a mounting block is mounted on the bottom surface of an inner cavity of the storage box, a turnover assembly is mounted between the mounting block and the storage box in a matched manner, a clamping assembly is mounted in the mounting block in a matched manner, and the turnover assembly is connected with the storage box. A plurality of placing grooves are uniformly formed in the top surface of the mounting block; according to the multi-mode immunohistochemical kit disclosed by the utility model, the overturning assemblies are arranged in the multi-mode immunohistochemical kit, and when the device is used, through mutual matching of structures in the assemblies, the second overturning plate can be protected when a test tube does not need to be overturned out by utilizing the first overturning plate, so that the first overturning plate and the second overturning plate are prevented from being mistakenly touched and overturned; and the effect of improving the safety of the device is achieved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of medical appliances, and particularly relates to a multi-modal immunohistochemical kit. BACKGROUND

[0002] The multi-modal immunohistochemical kit is an advanced tool for simultaneously detecting multiple biomarkers on the same tissue section, based on tyramide signal amplification technology (TSA), HRP catalyzing the addition of fluorescein substrate to the system, generating activated fluorescent substrate, covalently binding with tyrosine on the antigen, making the sample stably covalently bind with fluorescein, and then washing away the non-covalently bound antibody through heat repair, and then replacing another primary antibody and fluorescein substrate for the next round of incubation, so as to realize multiple labeling.

[0003] In the Chinese patent with publication number CN217779393U, an immunohistochemical kit is mentioned. When in use, the test tube is placed in the placing groove in the box body, and then the switch button is pressed to start the electric push rod. The electric push rod pushes the moving seat to move towards the cover plate, and at the same time, the connecting block is moved. At this time, the first sponge pad is pushed to move towards the second sponge pad by the movement of the connecting block, so that the first sponge pad and the second sponge pad are immediately recessed to form corresponding shapes according to the size of the test tube. The test tube in the placing groove can be clamped. This way can not only fix test tubes of different sizes, but also can avoid the test tube from shaking in the placing groove. When the reagent kit falls or collides, the first sponge pad and the second sponge pad can protect the test tube;

[0004] In the prior art, the pressing block can drive the fixed plate to flip, so as to quickly lift the test tube and take it out. However, the pressing block in the prior art is exposed to the outside. During use, the pressing block may be touched inadvertently, causing the fixed plate to flip accidentally, the test tube to be lifted quickly, and the liquid in the test tube to splash out, causing reagent waste and harm to surrounding personnel or equipment;

[0005] Therefore, the present scheme proposes a multi-modal immunohistochemical kit to solve the above problems. UTILITY MODEL CONTENTS

[0006] The utility model aims to provide a multi-modal immunohistochemical kit to solve the problem that the pressing block in the prior art is exposed to the outside, which may be touched inadvertently during use, causing the fixed plate to flip accidentally, the test tube to be lifted quickly, and the liquid in the test tube to splash out, causing reagent waste and harm to surrounding personnel or equipment.

[0007] In order to achieve the above object, the utility model provides the following technical scheme: a multimode immunohistochemical kit, including the storage box, the bottom surface of the storage box cavity is installed with the mounting block, the mounting block and the storage box are installed with the turnover assembly, the mounting block is installed with the clamping assembly, the top surface of the mounting block is evenly provided with a plurality of placing grooves;

[0008] The turnover assembly includes a second rotating shaft, a second rotating shaft is rotatably installed between the inner walls on the left and right sides of the placing groove, a turnover plate one is installed on the outer wall of the second rotating shaft, a turnover plate two is installed on the side wall of the turnover plate one, a groove is formed on the side of the turnover plate two away from the turnover plate one, a first rotating shaft is rotatably installed in the inner cavity of the groove, a turnover plate three is installed on the side wall of the first rotating shaft, a torsional spring one is sleeved on the first rotating shaft, one end of the torsional spring one is connected with the turnover plate two, the other end of the torsional spring one is connected with the turnover plate three, and a contact plate is installed on the side wall of the first rotating shaft.

[0009] Preferably, a plurality of through holes two are evenly formed in the side wall of the mounting block, a plurality of through holes one are evenly formed in the side wall of the storage box, the plurality of through holes two correspond to the plurality of through holes one, and the sizes of the plurality of through holes two are same as those of the plurality of through holes one.

[0010] Preferably, the turnover plate two is slidably installed in the through hole two, the turnover plate two is slidably installed in the through hole one, and elastic cloths are arranged on the top surface and the bottom surface of the turnover plate two.

[0011] Preferably, a support plate is installed on the bottom surface of the turnover plate one, a through groove is formed in the top surface of the turnover plate three, and a connecting piece is arranged in the through groove.

[0012] Preferably, the connecting piece includes a connecting rope, mounting rings are installed at the two ends of the connecting rope, and the mounting rings are clamped in the through groove.

[0013] Preferably, an installation groove is formed in the bottom surface of the through hole one, a positioning roller is installed on the side wall of the installation groove, and anti-skid lines are evenly arranged on the surface of the connecting piece.

[0014] Preferably, an installation ring is sleeved on the positioning roller.

[0015] Preferably, torsional springs two are sleeved on the outer walls of the second rotating shafts, one end of each torsional spring two is connected with the inner wall of the mounting block placing groove, and the other end of each torsional spring two is connected with the turnover plate one.

[0016] Compared with the prior art, the utility model has the advantages that:

[0017] 1. The utility model discloses a kind of multi-modal immunohistochemical kits, set up turnover assembly in a kind of, when using device by the cooperation between above-mentioned components structure, it is realized when not needing to utilize turnover plate one to turn out test tube, can protect turnover plate two, avoid turnover plate one and turnover plate two mistake touch turnover, reach the effect of improving the security of device, solve the problem that pressing block in prior art is exposed to outside, in the process of using, it can inadvertently touch pressing block, leading to fixed plate accidental turnover, test tube is quickly lifted, so as to cause liquid in test tube splash, cause reagent waste, and cause damage to surrounding personnel or equipment.

[0018] 2, the utility model discloses a kind of multi-modal immunohistochemical kits, set up turnover assembly, connecting piece and positioning roller in a kind, when using device by the cooperation between above-mentioned structure, it is realized after turnover turnover plate one, the position of turnover plate one can be limited, avoid turnover plate one to drive test tube reset, the problem that staff needs to repeatedly operate turnover plate one turnover, reach the effect of simplifying operation process, improve work efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 It is the perspective view of the utility model;

[0020] Figure 2 It is the explosion view of the utility model;

[0021] Figure 3 It is the structure diagram of turnover assembly of the utility model;

[0022] Figure 4 It is the schematic diagram of clamping assembly installation structure of the utility model;

[0023] Figure 5 It is the utility model Figure 2 Middle A enlarged structure diagram;

[0024] Figure 6 It is the utility model Figure 3 Middle B enlarged structure diagram;

[0025] Figure 7 It is the utility model Figure 3 Middle C enlarged structure diagram;

[0026] Figure 8 It is the section view of installation block of the utility model;

[0027] Figure 9 It is the structure diagram of connecting piece of the utility model.

[0028] In the figure: 1, storage box; 2, through hole one; 3, clamping assembly; 4, mounting block; 5, placing groove; 6, elastic cloth; 7, turnover assembly; 701, turnover plate one; 702, turnover plate two; 703, groove; 704, pivot one; 705, turnover plate three; 706, torsional spring one; 707, pivot two; 708, torsional spring two; 709, support plate; 710, through slot; 711, abutting plate; 8, through hole two; 9, mounting groove; 10, connecting piece; 101, connecting rope; 102, mounting ring; 11, positioning roller. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0030] Referring to Figure 1 Figure 9 The utility model provides a multimode immunohistochemical kit, including storage box 1, the installation block 4 is installed in the inner chamber bottom surface of storage box 1, and the turnover assembly 7 is installed between installation block 4 and storage box 1, and the clamping assembly 3 is installed in the installation block 4, and a plurality of placing grooves 5 are evenly arranged on the top surface of installation block 4,

[0031] The turnover assembly 7 includes pivot two 707, pivot two 707 is rotatably installed between the inner walls on the left and right sides of placing groove 5, pivot one 701 is installed on the outer wall of pivot two 707, turnover plate two 702 is installed on the side wall of pivot one 701, groove 703 is formed on the side, away from pivot one 701, of turnover plate two 702, pivot one 704 is rotatably installed in the inner chamber of groove 703, turnover plate three 705 is installed on the side wall of pivot one 704, torsional spring one 706 is sleeved on pivot one 704, one end of torsional spring one 706 is connected with turnover plate two 702, the other end of torsional spring one 706 is connected with turnover plate three 705, and abutting plate 711 is installed on the side wall of pivot one 704.

[0032] When the device normally stores the test tube, under the action of torsional spring one 706, turnover plate three 705 and abutting plate 711 will be perpendicular in the inside of through hole one 2, and turnover plate two 702 is also located in the inside of through hole one 2, avoiding the problem that turnover plate one 701 is turned over due to the mistaken touch of the staff.

[0033] In further embodiments, referring to Figures 1-3 ​The side walls of the mounting block 4 are uniformly provided with a plurality of through holes two 8, the side walls of the receiving box 1 are uniformly provided with a plurality of through holes one 2, the plurality of through holes two 8 correspond to the plurality of through holes one 2, and the sizes are the same;

[0034] The through hole two 8 is slidably provided with a turnover plate two 702, the through hole one 2 is slidably provided with the turnover plate two 702, the top surface and the bottom surface of the turnover plate two 702 are respectively provided with elastic cloth 6, and the sides away from the turnover plate two 702 of the two elastic cloths 6 are respectively connected with the top surface and the bottom surface of the through hole two 8;

[0035] The turnover plate two 702 can be turned over and slid in the through hole one 2 and the through hole two 8, which facilitates the turnover of the turnover plate one 701, and the provision of the elastic cloth 6 gives a layer of isolation between the inside and the outside of the receiving box 1, reducing the interaction between the inside and the outside of the device.

[0036] In further embodiments, with reference to Figure 1 - Figure 9 The bottom surface of the turnover plate one 701 is provided with a support plate 709, the top surface of the turnover plate three 705 is provided with a through slot 710, and the through slot 710 is provided with a connecting piece 10;

[0037] The connecting piece 10 includes a connecting rope 101, both ends of the connecting rope 101 are respectively provided with a mounting ring 102, and the mounting ring 102 is clamped in the through slot 710;

[0038] The bottom surface of the through hole one 2 is provided with a mounting slot 9, the side wall of the mounting slot 9 is provided with a positioning roller 11, and the surface of the connecting piece 10 is uniformly provided with anti-skid lines, which are used to increase the friction between the positioning roller and the mounting ring 102, avoid the falling of the mounting ring 102, and the mounting ring 102 is sleeved on the positioning roller 11;

[0039] When the turnover plate one 701 is turned over to take out the test tube, the mounting ring 102 is sleeved on the positioning roller 11, the two mounting rings 102 limit the positions of the turnover plate three 705 and the positioning roller 11 through the connecting rope 101, avoid the resetting of the turnover plate one 701, and realize the limitation of the position of the turnover plate one 701 after the turnover plate one 701 is turned over, avoiding the resetting of the test tube by the turnover plate one 701 and the repeated operation of the turnover plate one 701 by the staff.

[0040] In further embodiments, with reference to Figures 1-8 The outer walls of the shaft two 707 are respectively sleeved with torsional springs two 708, one end of the torsional spring two 708 is connected with the inner wall of the mounting block 4 placement slot 5, and the other end of the torsional spring two 708 is connected with the turnover plate one 701;

[0041] Wherein, after the test tube is taken out by the turnover plate one 701, the shaft two 707 and the turnover plate one 701 are driven to rotate and reset under the action of the torsion spring two 708, so that the convenience of the device is improved;

[0042] Meanwhile, the support plate 709 can assist the turnover plate one 701 to reset to the horizontal angle when the turnover plate one 701 resets, so that the automatic resetting effect of the turnover plate one 701 is realized.

[0043] The working principle of the utility model is as follows: when the device is used, the test tube is placed in the placing groove 5 and then positioned in the placing groove 5 by the clamping assembly 3;

[0044] When the test tube needs to be taken out from the placing groove 5, firstly, the clamping assembly 3 is started to release the positioning of the test tube by the clamping assembly 3, then the turnover torsion spring one 706 is pressed and the shaft one 704 is driven to rotate, with the rotation of the shaft one 704, the abutting plate 711 will abut against the turnover plate two 702, so that the turnover plate two 702 and the turnover plate one 701 are turned over, with the turnover of the turnover plate one 701, the test tube is pushed out by the turnover plate one 701;

[0045] Then the mounting ring 102 is sleeved on the positioning roller 11, the two mounting rings 102 limit the positions of the turnover plate three 705 and the positioning roller 11 through the connecting rope 101, so that the reset of the turnover plate one 701 is avoided, the position of the turnover plate one 701 is limited after the turnover plate one 701 is turned over, the problem that the turnover plate one 701 drives the test tube to reset is avoided, the staff needs to repeatedly operate the turnover plate one 701 to turn over, the operation process is simplified, and the working efficiency is improved.

[0046] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. A multi-modal immunohistochemistry kit comprising a housing (1), characterized in that, The bottom surface of the inner cavity of the storage box (1) is provided with a mounting block (4), the mounting block (4) and the storage box (1) are provided with a turnover assembly (7) in cooperation, the mounting block (4) is provided with a clamping assembly (3) in cooperation, and the top surface of the mounting block (4) is uniformly provided with a plurality of placing grooves (5). The turnover assembly (7) comprises a rotating shaft two (707), the rotating shaft two (707) is rotatably arranged between the inner walls of the left and right sides of the placing groove (5), the outer wall of the rotating shaft two (707) is provided with a turnover plate one (701), the side wall of the turnover plate one (701) is provided with a turnover plate two (702), the side, away from the turnover plate one (701), of the turnover plate two (702) is provided with a groove (703), the rotating shaft one (704) is rotatably arranged in the inner cavity of the groove (703), the side wall of the rotating shaft one (704) is provided with a turnover plate three (705), the rotating shaft one (704) is provided with a torsional spring one (706), one end of the torsional spring one (706) is connected with the turnover plate two (702), the other end of the torsional spring one (706) is connected with the turnover plate three (705), and the side wall of the rotating shaft one (704) is provided with a resisting plate (711).

2. The multi-modal immunohistochemistry kit of claim 1, wherein: The side wall of the mounting block (4) is uniformly provided with a plurality of through holes two (8), the side wall of the storage box (1) is uniformly provided with a plurality of through holes one (2), the plurality of through holes two (8) and the plurality of through holes one (2) correspond to each other and are of the same size.

3. The multi-modal immunohistochemistry kit of claim 2, wherein: The turnover plate two (702) is slidably arranged in the through hole two (8), the turnover plate two (702) is slidably arranged in the through hole one (2), the top surface and the bottom surface of the turnover plate two (702) are respectively provided with elastic cloth (6), and the top surface and the bottom surface of the through hole two (8) are respectively connected with the side, away from the turnover plate two (702), of the two elastic cloth (6).

4. The multi-modal immunohistochemistry kit of claim 3, wherein: The bottom surface of the turnover plate one (701) is provided with a supporting plate (709), the top surface of the turnover plate three (705) is provided with a through groove (710), and the through groove (710) is provided with a connecting piece (10).

5. The multi-modal immunohistochemistry kit of claim 4, wherein: The connecting piece (10) comprises a connecting rope (101), the two ends of the connecting rope (101) are respectively provided with a mounting ring (102), and the mounting ring (102) is clamped in the through groove (710).

6. The multi-modal immunohistochemistry kit of claim 5, wherein: The bottom surface of the through hole one (2) is provided with a mounting groove (9), the side wall of the mounting groove (9) is provided with a positioning roller (11), and the surface of the connecting piece (10) is uniformly provided with anti-skid lines.

7. The multi-modal immunohistochemistry kit of claim 6, wherein: The mounting ring (102) is sleeved on the positioning roller (11).

8. The multi-modal immunohistochemistry kit of claim 1, wherein: The outer walls of the rotating shaft two (707) are respectively sleeved with torsional springs two (708), one end of the torsional spring two (708) is connected with the inner wall of the placing groove (5) of the mounting block (4), and the other end of the torsional spring two (708) is connected with the turnover plate one (701).

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