Filtering and drying device for preparing vincristine sulfate

By designing a filtration and drying device with components such as a vacuum pump and a stirring rod, the problem of separating the desiccant from the drug in the preparation of vincristine sulfate was solved, enabling the reuse of the desiccant and reducing production costs.

CN223856052UActive Publication Date: 2026-01-30JIANGSU QINFEN PHARMA
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Patent Information

Application Number
CN202520292122.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-24
Publication Date
2026-01-30
Estimated Expiration
2035-02-24

AI Technical Summary

Technical Problem

In the current process of preparing vincristine sulfate, it is not easy to separate the granular or liquid desiccant from the drug, which leads to increased production costs and filtration difficulties.

Method used

The filtration and drying device, consisting of components such as a vacuum pump, exhaust pipe, filter plate, diaphragm pump, and stirring rod, achieves the separation and reuse of desiccant and vincristine sulfate through vacuum drying and stirring.

Benefits of technology

This method achieves effective separation of the desiccant and vincristine sulfate, reduces production costs, and improves drying efficiency and desiccant utilization.

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Abstract

The utility model relates to the technical field of vincristine sulfate drying and filtering, and particularly discloses a filtering and drying device for vincristine sulfate preparation, which comprises a base, two pairs of supporting columns are fixedly connected to the upper surface of the base, a kettle tank is fixedly connected to one side wall of each supporting column, connecting blocks are fixedly connected to the periphery of the kettle tank, and fixing bolts are in threaded connection with the interiors of the connecting blocks. The upper surface of the kettle tank is movably connected with a top plate, the upper surface of the top plate is fixedly connected with a vacuum pump, one side wall of the vacuum pump is fixedly connected with an exhaust pipe, the other side of the vacuum pump is fixedly connected with an exhaust port, one side wall of the kettle tank is fixedly connected with a first discharge port, and the other side wall of the kettle tank is fixedly connected with a second discharge port. According to the vincristine sulfate drying device, through the arrangement of the vacuum pump, the exhaust pipe and the exhaust port, gas in the kettle tank can be pumped out, so that vincristine sulfate is dried through cold air, and through the cooperation of the diaphragm pump, the conveying pipe and the circulating pipe, a drying agent discharged from a filter plate can be recycled and can be fed into the kettle tank again.
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Description

TECHNICAL FIELD

[0001] The utility model relates to sulphuric acid vinblastine drying filter technical field, concretely is a kind of filter drying device for sulphuric acid vinblastine preparation. BACKGROUND

[0002] Sulphuric acid vinblastine, western medicine name. Common preparation is injection etc. It is used for acute leukemia, especially children's acute leukemia, and the curative effect of acute lymphocytic leukemia is remarkable;Malignant lymphoma;Germ cell tumor;Small cell lung cancer, Ewing's sarcoma, nephroblastoma, neuroblastoma;Breast cancer, chronic lymphocytic leukemia, digestive tract cancer, melanoma and multiple myeloma etc.

[0003] But the natural air drying of existing sulphuric acid vinblastine, intermediate will mix and mix granular or liquid desiccant, and granular or liquid desiccant discharge will bring sulphuric acid vinblastine, increase production cost, and it is not easy to filter for granular desiccant and sulphuric acid vinblastine, to lead to granular desiccant and sulphuric acid vinblastine discharge together. INVENTION CONTENTS

[0004] In view of the deficiencies of prior art, the utility model provides a kind of filter drying device for sulphuric acid vinblastine preparation, solve the problem that sulphuric acid vinblastine is not easy to separate with granular and liquid desiccant by natural air drying.

[0005] To realize above-mentioned purpose, the utility model is realized by following technical scheme: a kind of filter drying device for sulphuric acid vinblastine preparation, including base, the upper surface of the base is fixedly connected with two pairs of support column, the side wall of the support column is fixedly connected with kettle, the periphery of the kettle is fixedly connected with connecting block, the inside of the connecting block is threadedly connected with fixed bolt, the upper surface of the kettle is movably connected with top plate, the upper surface of the top plate is fixedly connected with vacuum pump, the side wall of the vacuum pump is fixedly connected with exhaust pipe, the other side of the vacuum pump is fixedly connected with exhaust port, the side wall of the kettle is fixedly connected with first discharge port, the other side wall of the kettle is fixedly connected with second discharge port, the upper surface of the base is provided with drive mechanism, the inside of the kettle is fixedly connected with filter plate.

[0006] Preferably, the drive mechanism includes a servo motor, the servo motor is located on the upper surface of the base, the side wall of the servo motor is rotatably connected with a rotating shaft, the outer wall of the rotating shaft is rotatably connected with a first meshing gear.

[0007] Preferably, the side wall of the first meshing gear is meshed with a second meshing gear, the inside of the second meshing gear is rotatably connected with a rotating shaft, the upper surface of the rotating shaft is provided with a filtering mechanism.

[0008] Preferably, the filtering mechanism comprises a rotating plate, a position of the rotating plate is provided with an outer wall of a rotating shaft, four groups of stirring rods are rotationally connected to the outer wall of the rotating shaft, and a blower is rotationally connected to the top end of the rotating shaft.

[0009] Preferably, one side wall of the kettle is fixedly connected with a feeding port, one side wall of the kettle is fixedly connected with a diaphragm pump, one side wall of the diaphragm pump is fixedly connected with a conveying pipe, the conveying pipe is arranged on the upper side of the filter plate, one side wall of the diaphragm pump is fixedly connected with a circulating pipe, and the circulating pipe is arranged on the lower side of the filter plate.

[0010] Beneficial effects

[0011] The utility model provides a filter drying device for vinblastine sulfate preparation, which has the following beneficial effects compared with the prior art:

[0012] (1) The vacuum pump, exhaust pipe and exhaust port are arranged to extract the gas in the kettle, so that the vinblastine sulfate is dried by cold air. The diaphragm pump, conveying pipe and circulating pipe are cooperated to recycle the drying agent falling from the filter plate, so that the drying agent can be sent into the kettle again. The first discharge port and the second discharge port are arranged to separate and discharge the drying agent and the vinblastine sulfate. The filter plate is arranged to separate the vinblastine sulfate and the drying agent. The vinblastine sulfate stays on the drying plate. The blower and the stirring rod are used to air-cool and dry the vinblastine sulfate. The stirring rod stirs the vinblastine sulfate, so that the vinblastine sulfate below can also contact the cold air. The blower blows the cold air to the upper surface of the vinblastine sulfate, so as to air-cool the vinblastine sulfate. The rotating plate is arranged to stir the drying agent, so that the drying agent is sent into the circulating pipe and then sent into the filter plate again by the diaphragm pump. BRIEF DESCRIPTION OF DRAWINGS

[0013] Fig. 1 FIG. 1 is a schematic view of the structure of the filter drying device for vinblastine sulfate preparation according to an embodiment of the present application;

[0014] Fig. 2 FIG. 2 is a schematic view of the driving and filtering mechanism structure according to an embodiment of the present application;

[0015] Fig. 3 FIG. 3 is a schematic view of the stirring and conveying mechanism structure according to an embodiment of the present application.

[0016] In the figure: 1, base; 2, support column; 3, kettle; 4, connecting block; 5, fixed bolt; 6, top plate; 7, vacuum pump; 8, exhaust pipe; 9, exhaust port; 10, first discharge port; 11, second discharge port; 12, servo motor; 13, rotating shaft; 14, first meshing gear; 15, second meshing gear; 16, rotating shaft; 17, rotating plate; 18, filter plate; 19, stirring rod; 20, blower; 21, feed inlet; 22, diaphragm pump; 23, transport pipe; 24, circulation pipe. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0018] Embodiment 1

[0019] Please refer to Figs. 1-3 As shown in the figure, the embodiment proposes a filtering and drying device for preparing vinblastine sulfate, which comprises a base 1, the upper surface of the base 1 is fixedly connected with two pairs of support columns 2, one side wall of the support column 2 is fixedly connected with a kettle 3, the four around of the kettle 3 is fixedly connected with a connecting block 4, the inside of the connecting block 4 is threadedly connected with a fixed bolt 5, the upper surface of the kettle 3 is movably connected with a top plate 6, the upper surface of the top plate 6 is fixedly connected with a vacuum pump 7, one side wall of the vacuum pump 7 is fixedly connected with an exhaust pipe 8, the other side of the vacuum pump 7 is fixedly connected with an exhaust port 9, one side wall of the kettle 3 is fixedly connected with a first discharge port 10, the other side wall of the kettle 3 is fixedly connected with a second discharge port 11, the upper surface of the base 1 is provided with a driving mechanism, the inside of the kettle 3 is fixedly connected with a filter plate 18, since the support column 2 can support the kettle 3, the connecting block 4 and the fixed bolt 5 can close or separate the top plate 6 and the kettle 3, and the vacuum pump 7, the exhaust pipe 8 and the exhaust port 9 can exhaust the gas in the kettle 3, so that the vinblastine sulfate is dried by cold air, and the first discharge port 10 and the second discharge port 11 can separate and discharge the drying agent and the vinblastine sulfate.

[0020] Preferably, the driving mechanism comprises a servo motor 12, the position of the servo motor 12 is arranged on the upper surface of the base 1, one side wall of the servo motor 12 is rotatably connected with a rotating shaft 13, the outer wall of the rotating shaft 13 is rotatably connected with a first meshing gear 14, since the servo motor 12 and the rotating shaft 13 are adopted, the first meshing gear 14 can be rotated, so as to drive the second meshing gear 15 to mesh transmission.

[0021] Preferably, one side wall of the first meshing gear 14 is meshingly connected with the second meshing gear 15, the inside of the second meshing gear 15 is rotationally connected with the rotating shaft 16, the upper surface of the rotating shaft 16 is provided with the filtering mechanism, and the second meshing gear 15 and the rotating shaft 16 can drive the rotating plate 17 and the stirring rod 19 to rotate.

[0022] Preferably, the filtering mechanism comprises the rotating plate 17, the position of the rotating plate 17 is arranged on the outer wall of the rotating shaft 16, the outer wall of the rotating shaft 16 is rotationally connected with four groups of the stirring rod 19, the outer wall of the top end of the rotating shaft 16 is rotationally connected with the air blower 20, the rotating plate 17 can send the drying agent to one side of the circulating pipe 24, so that the drying agent is sent to the upper side of the filter plate 18 by the diaphragm pump 22, and the drying agent is mixed with the new vinblastine sulfate again.

[0023] Preferably, one side wall of the kettle 3 is fixedly connected with the feeding port 21, one side wall of the kettle 3 is fixedly connected with the diaphragm pump 22, one side wall of the diaphragm pump 22 is fixedly connected with the conveying pipe 23, the conveying pipe 23 is arranged on the upper side of the filter plate 18, one side wall of the diaphragm pump 22 is fixedly connected with the circulating pipe 24, and the circulating pipe 24 is arranged on the lower side of the filter plate 18, the diaphragm pump 22, the conveying pipe 23 and the circulating pipe 24 can make the drying agent falling from the filter plate 18 to be sent to the upper side of the filter plate 18, so that the drying agent is mixed with the vinblastine sulfate again, and the drying agent absorbs the moisture in the vinblastine sulfate.

[0024] In use, the vinblastine sulfate and the drying agent are sent into the feeding port 21 by the staff, then the servo motor 12 is started to drive the rotating shaft 13, so that the rotating shaft 13 drives the first meshing gear 14 and the second meshing gear 15 to rotate, the vinblastine sulfate and the drying agent are left on the filter plate 18, the drying agent absorbs the moisture contained in the vinblastine sulfate and then falls from the filter plate 18 to the bottom end in the kettle 3, the rotating shaft 16 rotates to drive the stirring rod 19 and the rotating plate 17 to rotate respectively, the rotating plate 17 sends the drying agent to one side of the first discharge port 10 or the circulating pipe 24, so that the drying agent is discharged from the first discharge port 10 or sent into the circulating pipe 24, the stirring rod 19 fully mixes the drying agent and the vinblastine sulfate, the vacuum pump 7 uses the exhaust pipe 8 to discharge the cavity in the kettle 3 from the exhaust port 9, and the diaphragm pump 22 uses the circulating pipe 24 to send the drying agent from the lower side of the filter plate 18 to the upper side of the filter plate 18, so that the drying agent absorbs the moisture from the new vinblastine sulfate.

[0025] The preferred embodiments disclosed above are only used to help describe the utility model. The preferred embodiments do not describe all the details and do not limit the utility model to the specific implementation. Obviously, according to the content of the specification, many modifications and changes can be made. The specification selects and specifically describes these embodiments in order to better explain the principle and practical application of the utility model, so that the person skilled in the art can well understand and utilize the utility model. The utility model is limited by the claims and the whole scope and equivalents thereof.

Claims

1. A filter-drying apparatus for preparing vincristine sulfate, characterized by: The utility model provides a kind of vacuum filtration device, including base (1), the upper surface of base (1) is fixedly connected with two pairs of support column (2), one side wall of support column (2) is fixedly connected with kettle (3), and the periphery of kettle (3) is fixedly connected with connecting block (4), the inside of connecting block (4) is threadedly connected with fixed bolt (5), the upper surface of kettle (3) is movably connected with top plate (6), the upper surface of top plate (6) is fixedly connected with vacuum pump (7), one side wall of vacuum pump (7) is fixedly connected with exhaust pipe (8), the other side of vacuum pump (7) is fixedly connected with exhaust port (9), one side wall of kettle (3) is fixedly connected with first discharge port (10), the other side wall of kettle (3) is fixedly connected with second discharge port (11), the upper surface of base (1) is provided with driving mechanism, and the inside of kettle (3) is fixedly connected with filter plate (18).

2. A filtering and drying device for the preparation of vinblastine sulfate according to claim 1, characterized in that: The driving mechanism includes servo motor (12), the position of servo motor (12) is arranged on the upper surface of base (1), one side wall of servo motor (12) is rotatably connected with rotating shaft (13), and the outer wall of rotating shaft (13) is rotatably connected with first meshing gear (14).

3. A filtering and drying device for the preparation of vinblastine sulfate according to claim 2, characterized in that: The side wall of first meshing gear (14) is meshed with second meshing gear (15), the inside of second meshing gear (15) is rotatably connected with rotating shaft (16), and the upper surface of rotating shaft (16) is provided with filtering mechanism.

4. A filtering and drying device for the preparation of vinblastine sulfate according to claim 3, characterized in that: The filtering mechanism includes rotating plate (17), the position of rotating plate (17) is arranged on the outer wall of rotating shaft (16), the outer wall of rotating shaft (16) is rotatably connected with four groups of stirring rod (19), and the outer wall of the top end of rotating shaft (16) is rotatably connected with blower (20).

5. A filtering and drying device for the preparation of vinblastine sulfate according to claim 1, characterized in that: One side wall of kettle (3) is fixedly connected with feed inlet (21), one side wall of kettle (3) is fixedly connected with diaphragm pump (22), one side wall of diaphragm pump (22) is fixedly connected with transport pipe (23), and transport pipe (23) is arranged on the upside of filter plate (18), one side wall of diaphragm pump (22) is fixedly connected with circulation pipe (24), and circulation pipe (24) is arranged on the downside of filter plate (18).