Rapid replacing and fixing device for liquid chromatographic column

Abstract

The utility model discloses a liquid chromatographic column rapid replacing and fixing device which comprises a base and an adjusting assembly arranged at the upper end of the base, and the adjusting assembly is used for adjusting the height and the clamping position of a liquid chromatographic column. The device further comprises a clamping assembly arranged on one side of the adjusting assembly, the clamping assembly is used for ensuring stable clamping of liquid chromatographic columns with different calibers and types, and the base is in threaded connection with a leveling module. The utility model belongs to the technical field of experimental auxiliary equipment, and particularly relates to a quick replacing and fixing device for a liquid chromatographic column.

Description

TECHNICAL FIELD

[0001] The utility model belongs to experimental auxiliary equipment technical field especially, relate to a liquid chromatography column quick replacement and fixing device. BACKGROUND

[0002] Liquid chromatography is a separation and analysis technology widely used in chemical, biological, pharmaceutical and other fields, which can be used for separating and detecting various compounds in complex samples, and plays a key role in drug research and development, food safety detection, environmental monitoring and other work.

[0003] The traditional chromatography column replacement process usually needs to use multiple tools, and the operation steps are complicated, such as carefully unscrewing the connecting nut, disassembling the pipeline, etc. It also takes a long time for skilled operators, and may cause pipeline damage or leakage due to improper operation.

[0004] The conventional fixing method may not guarantee the accuracy and stability of the installation position of the chromatography column, and may cause the chromatography column to tilt, loosen and other situations, which may affect the separation effect and the accuracy of the analysis results, and may also cause the chromatography column to be damaged prematurely, increasing the maintenance cost of the instrument.

[0005] In the laboratory or production environment where the chromatography column needs to be frequently replaced, such as a drug research and development laboratory, different types of chromatography columns may need to be quickly switched according to different experimental requirements. The complex replacement and unstable fixing method may seriously reduce the work efficiency, increase the labor cost and time cost. INVENTION CONTENTS

[0006] In view of the above situation, in order to overcome the defects of the prior art that the replacement process of different types of liquid chromatography columns is complicated and cannot ensure the stability of the clamping of the chromatography column.

[0007] The utility model adopts the technical scheme as follows: a liquid chromatography column quick replacement and fixing device, including base, and adjusting assembly setting in the upper end of base, adjusting assembly is used for realizing the height and clamping position adjustment of liquid chromatography column, still including the clamping assembly setting in one side of adjusting assembly, clamping assembly is used for ensuring the stable clamping of different caliber and kind liquid chromatography column, the leveling module is connected with screw on the base.

[0008] Further, the adjusting assembly includes a positioning block, a slide rod, a sliding block one and a positioning pin, the positioning block is fixedly connected to the upper end of the base by a fixing pin, the slide rod is symmetrically fixed to the upper end of the positioning block along the central axis of the fixing block, the sliding block one is spaced apart and slidably arranged between the slide rods, the positioning pin is threadedly arranged at one end of the sliding block one, and the slide rod is fixedly connected with the fixing block at the upper end.

[0009] Further, the clamping assembly comprises a support block, a sliding block two, a double helix screw rod and a clamping frame, the support block is fixed between the sliding block one, one end of the support block is provided with a sliding groove, the sliding block two is symmetrically arranged in the sliding groove along the central axis of the support block, the double helix screw rod is arranged at both ends of the sliding groove, and the thread on the double helix screw rod is threadedly connected with the inner side of the through hole in the middle of the sliding block two.

[0010] Further, the leveling module is four groups, and the leveling module is symmetrically arranged along the central axis of the base, and the leveling module comprises an adjusting rod and a suction cup, the adjusting rod is threadedly connected to the base, and the suction cup is fixed to the lower end of the adjusting rod.

[0011] Further, the positioning block is provided with a reinforcing rib at both ends, the reinforcing rib is provided with a positioning hole one, and the base is provided with a positioning hole two in communication with the positioning hole one.

[0012] Further, the clamping frame is arc-shaped, and the inner side of the clamping frame is provided with a non-slip pad.

[0013] After the above structure is adopted, the beneficial effects of the present application are as follows:

[0014] (1) Through the linkage of the positioning block, the sliding rod, the sliding block one and the positioning bolt in the adjusting assembly, the height of the adjusting assembly and the sliding block one and the distance between the sliding block one can be adjusted to adapt to different specifications of the chromatographic column.

[0015] (2) Through the linkage of the support block, the sliding block two, the double helix screw rod and the clamping frame in the clamping assembly, the distance between the sliding block two can be adjusted, when the distance between the clamping frames reaches the appropriate position, the sliding block two is driven by the double helix screw rod to fix the clamping frame, so that the clamping frame closely fits the chromatographic column, and rapid clamping is realized. BRIEF DESCRIPTION OF DRAWINGS

[0016] The accompanying drawings are used to provide a further understanding of the present application, and constitute a part of the specification, and are used to explain the present application together with embodiments of the present application, and do not constitute a limitation on the present application.

[0017] Figure 1 It is a schematic diagram of the overall structure of the present application;

[0018] Figure 2 It is a schematic diagram of the overall structure of the present application; Figure 1 ;

[0019] Figure 3 It is a schematic diagram of the overall structure of the present application; Figure 2 ;

[0020] Figure 4 It is an explosion schematic diagram of the overall structure of the present application;

[0021] Figure 5 For the utility part structure amplification schematic diagram;

[0022] Figure 6 For Figure 3 A part of the enlarged view.

[0023] In the drawings: 1, base, 2, adjusting rod, 3, suction cup, 4, positioning block, 5, slide bar, 6, slide block one, 7, positioning bolt, 8, fixed block, 9, reinforcing rib, 10, positioning hole one, 11, positioning hole two, 12, support block, 13, slide block two, 14, double helix screw rod, 15, clamping frame, 16, non-slip pad. DETAILED DESCRIPTION

[0024] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the utility model.

[0025] It should be noted that, in this paper, relationship terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between the entities or operations. Moreover, the terms "include", "contain" or any other variants thereof are intended to cover non-exclusive inclusion, so that the process, method, article or equipment including a series of elements not only includes those elements, but also includes other elements not explicitly listed or inherent to such process, method, article or equipment.

[0026] As Figure 1 shown, a kind of liquid chromatographic column quick replacement and fixing device, it includes base 1, and the adjusting assembly of setting in the upper end of base 1, adjusting assembly is used to realize the height and clamping position adjustment of liquid chromatographic column;It further includes the clamping assembly of setting in the side of adjusting assembly, clamping assembly is used to ensure the stable clamping of different caliber and kind of liquid chromatographic column, and leveling module is screw-connected on base 1.

[0027] Wherein, leveling module is four groups, and leveling module is symmetrically arranged along the central axis of base 1, and leveling module includes adjusting rod 2 and suction cup 3, adjusting rod 2 is screw-connected on base 1, and suction cup 3 is fixedly connected to the lower end of adjusting rod 2, and the leveling of base 1 is realized by adjusting adjusting rod 2.

[0028] As Figures 2-3-4-5-6 as shown, the adjusting assembly comprises a positioning block 4, a slide bar 5, a sliding block one 6 and a positioning bolt 7, the positioning block 4 is fixedly connected to the upper end of the base 1 through a fixing bolt, the slide bar 5 is symmetrically fixed to the upper end of the positioning block 4 along the central axis of the fixed block 8, the sliding block one 6 is arranged between the slide bars 5 in a spaced sliding manner, the positioning bolt 7 is threadedly arranged at one end of the sliding block one 6, and the upper end of the slide bar 5 is fixedly connected with a fixed block 8.

[0029] Wherein, the positioning block 4 is symmetrically provided with a reinforcing rib 9 at both ends, the reinforcing rib 9 is provided with a positioning hole one 10, the base 1 is provided with a positioning hole two 11 in communication with the positioning hole one 10, and is made of high-strength, corrosion-resistant materials such as stainless steel or high-quality engineering plastics, the reinforcing rib 9 strengthens the stable connection between the positioning block 4 and the base 1, ensures the stable sliding of the sliding block one 6 on the slide bar 5, and adjusts the height of the sliding block one 6 and the spacing between the sliding block one 6 by arranging the sliding block in a spaced manner for different lengths of the chromatographic column, so as to adapt to chromatographic columns of different specifications.

[0030] As shown in Figures 4-5 , the clamping assembly comprises a supporting block 12, a sliding block two 13, a double helix screw rod 14 and a clamping frame, the supporting block 12 is fixedly connected between the sliding block one 6, the supporting block 12 is provided with a sliding groove at one end, the sliding block two 13 is arranged in the sliding groove in a symmetric manner along the central axis of the supporting block 12, the double helix screw rod 14 is arranged through both ends of the sliding groove, the thread on the double helix screw rod 14 is threadedly connected with the inner side of the through hole in the middle of the sliding block two 13, and the clamping frame is fixedly connected with the protruding end of the sliding block two 13.

[0031] Wherein, the clamping frame is arc-shaped, the inner side of the clamping frame is provided with an antiskid pad 16, the antiskid pad 16 ensures the clamping stability of the chromatographic column, the double helix screw rod 14 is adjusted to realize the opposite displacement of the sliding block two 13, the spacing between the adjusted sliding block two 13 is realized, when the spacing of the clamping frame reaches the appropriate position, the sliding block two 13 is driven by the double helix screw rod 14 to fix the clamping frame, so that the clamping frame closely fits the chromatographic column, and rapid clamping is realized.

[0032] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, the scope of the utility model is defined by the appended claims and their equivalents. In general, if those skilled in the art are inspired by it, without departing from the creative purpose of the utility model, similar structure modes and embodiments are not creatively designed, which should belong to the protection scope of the utility model.

Claims

1. A liquid chromatography column quick change and securement device, characterized by: It includes base (1), and the adjusting assembly arranged on the upper end of base (1), still include the clamping assembly arranged on the side of adjusting assembly, the base (1) is screw connected with leveling module on it; The adjusting assembly is connected through the linkage of positioning block (4), slide rod (5), slide block (6) and positioning bolt (7), for different length chromatographic column, the height of adjusting assembly and the interval between slide block (6) are adjusted, to adapt to different specifications of chromatographic column; The clamping assembly is connected through the linkage of supporting block (12), slide block (2) (13), double helix screw rod (14) and clamping frame (15), the interval between adjustable slide block (2) (13) can be adjusted, when the interval of clamping frame (15) reaches the appropriate position, slide block (2) (13) is driven by double helix screw rod (14) and clamping frame (15) is fixed, so that clamping frame (15) is tightly attached to chromatographic column, and quick clamping is realized.

2. The liquid chromatography column quick change and securement device of claim 1, wherein: The leveling module is four groups, and the leveling module is symmetrically arranged along the central axis of base (1), the leveling module includes adjusting rod (2) and suction cup (3), the adjusting rod (2) is screw connected on base (1), and the suction cup (3) is fixedly connected to the lower end of adjusting rod (2).

3. The device of claim 1, wherein: The adjusting assembly includes positioning block (4), slide rod (5), slide block (6) and positioning bolt (7), the positioning block (4) is fixedly connected to the upper end of base (1) through fixing bolt, the slide rod (5) is symmetrically fixedly connected to the upper end of positioning block (4) along the central axis of fixed block (8), the slide block (6) is spaced apart and slidably arranged between slide rod (5), and the positioning bolt (7) is screw threaded and arranged at one end of slide block (6), and the upper end of slide rod (5) is fixedly connected with fixed block (8).

4. The device according to claim 3, wherein: The positioning block (4) is symmetrically provided with reinforcing ribs (9) at both ends, the reinforcing ribs (9) are provided with positioning holes (10), and the base (1) is provided with positioning holes (11) in communication with the positioning holes (10).

5. The device of claim 4, wherein: The clamping assembly includes supporting block (12), slide block (2) (13), double helix screw rod (14) and clamping frame (15), the supporting block (12) is fixedly connected between slide block (6), one end of the supporting block (12) is provided with a sliding groove, the slide block (2) (13) is symmetrically arranged in the sliding groove along the central axis of the supporting block (12), the double helix screw rod (14) is arranged through both ends of the sliding groove, the threads on the double helix screw rod (14) are screw threaded and connected with the inner side of the through hole in the middle of the slide block (2) (13), and the clamping frame (15) is fixedly connected with the protruding end of the slide block (2) (13).

6. The device of claim 5, wherein: The clamping frame (15) is arc-shaped, and the inner side of the clamping frame (15) is provided with a non-slip pad (16).

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