Pipeline unfreezing device of medicine freeze dryer
By designing a thawing device for pharmaceutical freeze dryer pipes, which utilizes alternating current to generate eddy current for heating and thawing, the problem of frost and ice blockage in freeze dryer pipes and valves was solved, achieving a fast, safe, and energy-saving thawing effect.
Patent Information
- Application Number
- CN202423280960.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-30
- Publication Date
- 2026-01-30
- Estimated Expiration
- 2034-12-30
AI Technical Summary
Freeze dryer pipes and valves frost and ice blockage under high temperature and pressure, leading to expansion valve blockage, overheating or high pressure tripping, dirt blockage, ice blockage, and broken temperature-sensing capillary tubes, which are difficult to effectively defrost with existing technology.
A thawing device for pharmaceutical freeze dryer pipes was designed, comprising a circuit system consisting of a current detection module, a voltage detection module, an AC filter module, and a bridge rectifier module. The device generates a magnetic field through alternating current to heat the pipes by eddy currents, and then thaws the pipes by utilizing the Joule heating effect of the eddy currents.
It achieves rapid heating and defrosting, is energy-saving and environmentally friendly, highly multifunctional, safe, easy to operate, easy to communicate with other devices, has online precise temperature control, is explosion-proof and safe, and produces clean emissions.
Smart Images

Figure CN223859251U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the field of medical technology, especially a medical freeze-drying machine pipeline thawing device. BACKGROUND
[0002] Freeze drying is a technology that uses the principle of sublimation to dry, which is a process of rapidly freezing the material to be dried at low temperature, and then allowing the frozen water molecules to sublimate into water vapor in a suitable vacuum environment, so it has been widely used in the pharmaceutical field. However, under the action of high temperature and high pressure of the air compressor, the refrigerant changes from liquid to gas, so the water enters the narrow and long capillary tube along with the refrigerant circulation. When the filter is saturated with water, it cannot filter out the water, and when the temperature at the outlet of the capillary tube reaches 0℃, the water is separated from the refrigerant and forms frost and ice, causing ice blockage and preventing gas from being discharged. The expansion valve is often blocked, the outlet of the expansion valve is frozen and frosted, the high-pressure pipe is hot or the high-pressure machine is jumping, the dirty blockage, ice blockage, and temperature sensing capillary tube is broken: the drying filter is blocked and the compressor fails (there is a significant temperature difference between the inlet and outlet of the drying filter, or condensation occurs at the outlet of the filter). In order to solve the problem of frost and ice formation in the freeze-drying machine pipeline and valve, a freeze-drying machine pipeline and valve thawing device is developed. SUMMARY
[0003] The utility model provides a medical freeze-drying machine pipeline thawing device to solve the problems mentioned in the prior art.
[0004] In order to achieve the above-mentioned purpose, the utility model provides the following technical scheme:
[0005] A medical freeze-drying machine pipeline thawing device, comprising a current detection module, a voltage detection module, an AC filter module, an AC input module, a bridge rectifier module, a DC filter module, an operation display circuit, a power-on control module, a main control chip, a fan drive circuit, a synchronous circuit, a back pressure protection circuit, a surge protection circuit, a power drive circuit, an IGBT temperature detection module, a load detection module and a heating coil temperature circuit, the AC input module is connected to the AC filter module, the AC filter module is also connected to the bridge rectifier module and the current detection module respectively, the current detection module is also connected to the main control chip, the main control chip is also connected to the power-on control module, the fan drive circuit, the operation display circuit, the IGBT temperature detection module, the power drive circuit, the load detection module and the heating coil temperature circuit, the bridge rectifier module is also connected to the DC filter module, the DC filter module is also connected to the synchronous circuit, the back pressure protection circuit and the surge protection circuit respectively, and the power drive circuit is also connected to the synchronous circuit, the back pressure protection circuit and the surge protection circuit respectively.
[0006] As a further technical scheme of the utility model: the alternating current input module is 220V alternating current, the alternating current filter module includes filter capacitor C1, fuse FUSE1 and voltage-dependent resistor, the bridge rectifier module includes bridge rectifier BRIDGE2.
[0007] As a further technical scheme of the utility model: the main control chip includes chip IC1, and the model number of chip IC1 is S3F9454.
[0008] As a further technical scheme of the utility model: the surge protection circuit is constituted by resistance R203-R207, resistance R213-R218, capacitor C201-C207, diode D204, diode D206 and chip U3B, the model number of chip U3B is LM339, the reverse voltage protection circuit is composed of resistance R409, resistance R411, capacitor C406 and chip U3A, and the model number of chip U3A is LM339.
[0009] As a further technical scheme of the utility model: the synchronous circuit includes resistance R401, resistance R404-R408, resistance R416, resistance R417, capacitor C400-C402 and chip U3C.
[0010] As a further technical scheme of the utility model: the operation display circuit includes resistance R04-R09, switch SW1-SW6, indicating lamp LED1-LED6, resistance R10-R12 and interface CN1.
[0011] As a further technical scheme of the utility model: the IGBT temperature detection module includes thermistor RT2 and capacitor C512, the heating wire coil temperature circuit includes heating wire coil surface temperature circuit and heating wire coil temperature measurement circuit, the heating wire coil surface temperature circuit includes thermistor A01, resistance R506 and interface CON3, and the heating wire coil temperature measurement circuit includes thermistor RT1 and interface CN1.
[0012] As a further technical scheme of the utility model: the voltage detection module includes capacitor C200, resistance R220, resistance R221, resistance R202, resistance R222 and resistance R223, and the current detection module is constituted by current detection sampling transformer CT1, resistance R100, capacitor C100, capacitor C101, diode D100-D103, slide rheostat VR1 and resistance R101.
[0013] As a further technical scheme of the utility model: the fan driving circuit includes triode Q501, resistance R509, capacitor C515, fan and interface CN2.
[0014] As a further technical scheme of the utility model: the power drive circuit includes chip U3D, triode Q300, triode Q301, resistance R300-R303 and diode D300, the model of chip U3D is LM339, the power drive circuit is connected with main oscillation loop, and the main oscillation loop includes capacitor C4, IGBT1 and inductor L1.
[0015] In the above technical scheme, the utility model provides technical effect and advantage:
[0016] 1, heating speed is fast - can make the temperature of electric heating disc in 15 seconds to 100 degrees, and the speed is far faster than other devices.
[0017] 2, energy saving and environmental protection - no open fire, wire reel self-heating, reduces heat transfer loss, so its thermal efficiency can reach 80% to 92% or more, and no waste gas emission, no noise. Adopt prefabricated porcelain stainless steel pipeline can be online real-time to the thawing pipeline that needs to be thawed and control the heating.
[0018] 3, multi-functionality - can select appropriate options such as "water pipeline", "oil pipeline", "liquid gas pipeline" according to thawing medium. Temperature and heating time can be adjusted arbitrarily.
[0019] 4, easy to clean - no fuel residue and waste gas pollution.
[0020] 5, high explosion-proof safety - unlike other devices, it is not easy to produce gas and liquid leakage, and no open flame, safety is obviously superior to other devices, and can work reliably in explosive environment. In particular, it is provided with multiple safety protection measures, including furnace body inclination power off, over-time power off, over-current, over-voltage, under-voltage protection, improper use automatic stop and the like.
[0021] 6, convenient to use - the "one-key operation" indication of the device is very humanized, easy to operate, and the furnace body itself is only a few kilograms, so it is not a problem to take it anywhere, as long as there is power supply.
[0022] 7, easy to communicate with the control system of other equipment - the device can be associated with the control system of other equipment.
[0023] 8, online accurate temperature control - prefabricated porcelain stainless steel pipeline can be used to control the temperature of the thawing pipeline and valve. BRIEF DESCRIPTION OF DRAWINGS
[0024] Figure 1 It is the principle schematic view of the utility model.
[0025] Figure 2 is a schematic view of a prefabricated stainless steel ceramic pipeline connection.
[0026] Figure 3 is a schematic view of a prefabricated stainless steel ceramic pipeline section.
[0027] Figure 4 is an electrical schematic diagram of the present application.
[0028] Figure 5 is a circuit flow diagram of the present application.
[0029] Figure 6 is a detailed circuit diagram of the present application.
[0030] In the figure: 1-flange, 2-ceramic resistance winding, 3-ceramic resistance, 4-seamless stainless steel pipe, 5-aeronautical plug, 6-prefabricated stainless steel ceramic pipeline, 7-outgoing line one, 8-outgoing line two, 9-frosting pipeline, 10-soft body inductance electric heating disc. DETAILED DESCRIPTION
[0031] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative work fall within the scope of the present application.
[0032] It should be noted that the terms "vertical", "horizontal", "up", "down", "left", "right" and similar expressions used herein are only for the purpose of illustration, and do not represent the only implementation.
[0033] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present application belongs; the terms used in the specification of the present application are only for the purpose of describing specific embodiments, and are not intended to limit the present application; the term "and / or" used herein includes any and all combinations of one or more related listed items.
[0034] Example 1: as Figures 1-3As shown, the physical principle of the thawing device is to use electromagnetic induction phenomenon, that is, to use alternating current through the coil to generate alternating magnetic field with changing direction. The internal of the conductor in the alternating magnetic field will appear eddy current (the reason can refer to Faraday's law of electromagnetic induction), which is caused by the eddy electric field pushing the movement of the carrier in the conductor. The Joule heating effect of the eddy current makes the conductor warm, thereby realizing thawing of the freeze-drying machine pipeline valve. The device mainly consists of a freeze-drying machine pipeline valve thawing controller (explosion-proof type) and a soft inductive electric heating disc (explosion-proof type) / ceramic stainless steel pipeline (optional). The alternating current passes through the soft inductive electric heating disc or the ceramic stainless steel pipeline to generate a magnetic field. When the magnetic lines of force in the magnetic field pass through the pipeline, eddy current is generated to make the pipeline heat rapidly, thereby achieving the purpose of thawing the frozen pipeline.
[0035] Example 2: on the basis of example 1, as shown in the design, the circuit part is composed of rectifier filter, low-voltage power supply circuit, control circuit (CPU), PWM pulse driving circuit, surge and reverse voltage protection circuit, temperature and load detection loop, soft body inductive electric heating disc. Figure 4
[0036] 220V AC voltage is input into the device and divided into two paths. One path is output to the rectifier filter circuit after being reduced by a step-down transformer to become low-voltage DC for power supply of the control circuit. The other path is output +300V high voltage after 220V AC passes through a bridge rectifier stack, and then LC filtering provides working voltage for the "soft inductive electric heating disc". The current flowing through the "soft inductive electric heating disc" is controlled by the IGBT tube (gate-controlled tube). When the IGBT tube (gate-controlled tube) receives the PWM pulse driving signal output by the CPU, the IGBT tube (gate-controlled tube) is turned on / off to form a switching oscillation state, and then a high-frequency oscillation current is formed in the furnace disc coil. The capacitor C and the furnace disc coil are connected in parallel to form a resonance circuit, so that the amplitude of LC oscillation is very strong, with a peak value of 1000V.
[0037] The surge and reverse voltage protection circuit is used to prevent the surge voltage and the IGBT reverse peak voltage from being too high to protect the IGBT switch tube.
[0038] The load sensing loop (current detection loop) converts the working current of the IGBT into a voltage signal and adds it to the CPU. After the CPU processes the voltage, the amplitude of the IGBT signal is controlled, thereby automatically adjusting the working current of the IGBT tube.
[0039] The temperature sensing loop includes IGBT temperature detection (to prevent the temperature of the IGBT from being too high) and "soft inductive electric heating disc" temperature detection (to prevent the temperature of the electric heating disc from being too high).
[0040] The working principle is as follows:
[0041] As shown in Figures 5-6 The design mainly includes: main oscillation circuit, IGBT drive circuit, drive square wave pulse forming circuit, sawtooth square wave pulse forming circuit, synchronous pulse forming circuit, power-on delay protection circuit and switching circuit, surge protection circuit, reverse voltage protection circuit, current detection circuit, input voltage detection circuit, coil temperature, load temperature, IGBT tube temperature detection circuit, cooling fan drive circuit, switching power supply part.
[0042] I. Main oscillation circuit: composed of IGBT1, C4, OUT1 and OUT2 linked coil. Its role is to form a changing oscillation current in the coil. When the G pole of IGBT has a driving voltage, IGBT1 is saturated and turned on, forming a path from 300V-coil-D pole-S pole, allowing the heating coil to store electrical energy; when the G pole of IGBT has no driving voltage, IGBT is completely cut off, and the electrical energy on the hot coil is charged to C4 from OUT2-C4 right-C4 left-OUT1-coil-OUT2; when the voltage of C4 is charged to the highest, the voltage on C4 is discharged through C4 right-OUT2-coil-OUT1-C4 left path. When the voltage on C4 is discharged to the lowest, a driving voltage will come through the control circuit to the G pole, making IGBT conduct again. Thus, a changing oscillation current is formed in the coil.
[0043] II. IGBT drive circuit: composed of Q300, Q301, R300-R303, D300. When the right square wave pulse of point B arrives, Q301 is turned on and Q300 is cut off, and a positive driving voltage of about 17V is injected into the G pole of IGBT through the path 18V-Q301 C pole-Q301 E pole-R302-D point-R301-G point-IGBT G pole-IGBT S pole-ground, making IGBT saturated and turned on; when the right negative square wave pulse of point B arrives, Q301 is cut off and Q300 is turned on, and D point loses voltage, making the injected voltage of IGBT G pole disappear and IGBT quickly cut off. The role of R303 is to provide a bias voltage for point B, so that Q300 and Q301 can quickly turn on and off. R302 and R301 are current limiting resistors, and the resistance values of these two resistors, especially R301, are different according to the power. R300 is designed to prevent the input driving voltage from being too high, and its two ends can also be connected in parallel with a 15V-18V zener diode, which has the same effect.
[0044] III. The driving square wave pulse forming circuit: by U3D 10, 11, 13 feet, its role is to form a square wave pulse for driving the tube. From the 10 feet sent after the sawtooth wave pulse and PWM signal from the 11 feet shaping, from the 13 feet output to get close to the square wave pulse signal, for driving tube, its 11 feet signal is from the CPU PWM output terminal through R414, R410.
[0045] IV. The sawtooth square wave pulse forming circuit; by R418, R412, C403, D400, its working frequency is subject to the CPU sent to the probe pulse tracking, also subject to U3C 14 feet output of the synchronous detection pulse control and square correction, after the CPU detects that correct, then from the CPU output corresponding PWM pulse.
[0046] V. Synchronization pulse forming circuit; by R401, R404-R408, R416, R417, C400-C402, U3C 8, 9, 14 feet, its role is to output synchronization detection signal. Normal 9 feet DC voltage is higher than the 8 feet voltage, 14 feet output high level, because 9 feet work in the DC voltage plus a changing voltage (from the current on the IGBT tube), 14 feet output high level is superimposed by a changing voltage, this high level voltage to the rear of the sawtooth wave forming oscillation circuit for waveform correction, output switching square wave pulse. Finally to control the IGBT tube working switch synchronization.
[0047] VI. Power on delay protection circuit: it is composed of Q201, R209, R210, R209, D205, Q200, R214, R208, R211, R212, its role is to plug in the power moment and shutdown can make IGBT reliable stop. When plugged in, by 300v through R209, R210, D205 to Q201 inject a high level, Q201 turn on, drive the tube B voltage through Q201 C, E short to ground, so that IGBT tube cut-off, at the same time, due to 5v form, CPU output low level, through R208 to Q200 B pole voltage is low, Q200 cut-off, Q201 saturation conduction, also to make IGBT cut-off purpose. When starting, CPU output start high level to point A, through R208 to Q200 B pole, make Q200 conduct, because R214 resistance is small, Q201 B pole voltage is pulled down to the conduction level, Q201 cut-off, its task is given to the detection circuit and power control circuit. If the detection circuit is normal, IGBT works, if not, the CPU output shutdown instruction (low level), Q201 is turned on again to achieve the purpose of protection.
[0048] Seven, surge protection circuit: by R203-R207, R213-R218, C201-C207, D204, D206, U3B's 6, 7, 1 foot constitutes. Normal, 300V through R203, R204, D204, R206, R218 to 6 foot voltage than 7 foot voltage is low, 1 foot output high level, at this time D206 cut-off, CPU output power-on signal is not affected, the system is normal operation. When the power surge voltage breakdown, 300V through R203, R204, D204, R206, R218 to 6 foot voltage will rise, 6 foot voltage is higher than the 7 foot reference voltage, 1 foot output low level, at this time D206 conduction, the CPU output high level to the site, so that R208, R211 voltage after the voltage to Q200 is lower than the conduction voltage, Q200 cut Q201 saturation conduction, cut off the IGBT drive pole, so that the IGBT tube cut-off.
[0049] Eight, reverse voltage protection circuit (anti-peak voltage protection circuit): it is composed of IGBT D pole sampling circuit pole U3A's 4, 5, 2 feet. Its function is to prevent IGBT tube due to high reverse peak voltage breakdown. Normal, by synchronous sampling circuit to 4 foot voltage than 5 foot voltage is low, 2 foot output high level, at this time to U3D's 11 foot sent PWM pulse voltage has no effect. When the current is too large or for some reason the reverse peak voltage increases, when 4 foot to obtain the pulse is higher than the 5 foot voltage, 2 foot output low level, through R411 will U3D's 11 foot sent PWM pulse voltage amplitude decreases, so that its device output power is reduced, to protect the IGBT purpose.
[0050] Nine, current detection circuit: it is composed of current detection sampling transformer CT1, R100, D100-D103, VR1, R101. Its main function is to convert the IGBT working current into voltage signal to the CPU, through the CPU to deal with this voltage after the control PWM signal amplitude, so as to automatically adjust the IGBT tube working current. CT I primary alternating current flowing through the secondary induced a variable voltage, this voltage through R100 amplitude after D100-D103 rectification, in VR1 after R101 again voltage division to the CPU's current detection terminal, CPU through the voltage detected with the set voltage comparison, to automatically control the output size of PWM signal, to automatically control the IGBT tube working current purpose.
[0051] X. Input voltage detection circuit: mainly composed of R200, R201, R220, R221, R202, C200, which is to detect the size of the input voltage to achieve the overvoltage and undervoltage protection of the mains. The mains voltage is rectified by a diode and then reaches a large pulse DC pulse through R200, R201, R220, R221, and then through R202 voltage division, C200 filtering to get the DC sampling voltage, input to the voltage detection VIN terminal of the CPU. This voltage is compared with the voltage set in the CPU, and if the voltage is higher or lower than the set voltage value, the CPU considers that the input voltage is too high or too low, and the CPU terminal outputs the shutdown instruction to force the IGBT tube to stop working.
[0052] XI. Wire coil temperature, load temperature, IGBT tube temperature detection circuit: for measuring wire coil temperature, load temperature, IGBT tube temperature, which is to convert the working temperature into a voltage signal by using the characteristics of negative temperature coefficient thermistor, and add it to the detection terminal of the CPU. When the voltage exceeds the set value, the shutdown instruction is output through the CPU control terminal, and the IGBT tube stops working.
[0053] XII. Cooling fan driving circuit: normally, the FAN terminal of the CPU outputs high level, which is added to the B pole of Q501 through R506 and R509, Q501 is saturated and conducts, and the 18V voltage of VCC is added to both ends of the cooling fan, and the fan rotates normally to cool the IGBT tube. When the FAN terminal of the CPU outputs low level 0V, Q501 is cut off through R506 and R509, and the potential of both ends of the fan is the same, without voltage drop, and the fan stops.
[0054] XIII. Switching power supply part: the switching power supply part is composed of power management chip TH202, transformer T500, voltage stabilizing tube Q500 and its peripheral circuit, which provides two power supplies, VCC (18v) and 5V), to provide working power and signal control for the CPU and other ICs.
[0055] It is apparent to those skilled in the art that the present application is not limited to the details of the foregoing exemplary embodiments, and that the present application can be implemented in other concrete forms without departing from the spirit or essential characteristics of the present application. Therefore, the embodiments should be considered in all respects as illustrative and not restrictive, the scope of the present application being defined by the appended claims rather than the foregoing description, and it is intended to encompass all changes and modifications that fall within the meaning and scope of equivalents of the claims.
[0056] Furthermore, it should be understood that although the description is made according to the embodiments, not every embodiment contains only one independent technical solution, and the description is made in this way only for the sake of clarity, and the person skilled in the art should understand the description as a whole, and the technical solutions in each embodiment have been properly combined to form other embodiments which are easily understood by the person skilled in the art.
Claims
1. A medical freeze-drying machine pipeline thawing device, comprising a current detection module, a voltage detection module, an alternating current filtering module, an alternating current input module, a bridge rectifier module, a direct current filtering module, an operation display circuit, a start-up control module, a main control chip, a fan driving circuit, a synchronization circuit, a back pressure protection circuit, a surge protection circuit, a power driving circuit, an IGBT temperature detection module, a load detection module and a heating wire disc temperature circuit, characterized in that, The AC input module is connected with an AC filter module, the AC filter module is further connected with a bridge rectifier module and a current detection module, the current detection module is further connected with a master control chip, the master control chip is further connected with a start control module, a fan driving circuit, an operation display circuit, an IGBT temperature detection module, a power driving circuit, a load detection module and a heating wire disc temperature circuit, the bridge rectifier module is further connected with a DC filter module, the DC filter module is further connected with a synchronization circuit, a reverse voltage protection circuit and a surge protection circuit, and the power driving circuit is further connected with the synchronization circuit, the reverse voltage protection circuit and the surge protection circuit.
2. The medical ly freeze-dried tube thawing device according to claim 1, characterized in that: The AC input module is 220V AC, the AC filter module comprises a filter capacitor C1, a fuse FUSE1 and a voltage-dependent resistor, and the bridge rectifier module comprises a bridge rectifier BRIDGE2.
3. The medical ly freeze-dried tube thawing device according to claim 1, characterized in that: The master control chip comprises a chip IC1, and the model of the chip IC1 is S3F9454.
4. The medical ly freeze-dried product pipe thawing device according to claim 1, characterized in that: The surge protection circuit is composed of resistors R203-R207, resistors R213-R218, capacitors C201-C207, a diode D204, a diode D206 and a chip U3B, the model of the chip U3B is LM339, the reverse voltage protection circuit is composed of a resistor R409, a resistor R411, a capacitor C406 and a chip U3A, and the model of the chip U3A is LM339.
5. The medical ly freeze-dried tube thawing apparatus according to claim 1, wherein: The synchronization circuit comprises resistors R401, R404-R408, a resistor R416, a resistor R417, capacitors C400-C402 and a chip U3C.
6. The medical ly freeze-dried tube thawing apparatus according to claim 1, wherein: The operation display circuit comprises resistors R04-R09, switches SW1-SW6, indicator lamps LED1-LED6, resistors R10-R12 and an interface CN1.
7. The medical ly freeze-dried tube thawing apparatus according to claim 1, wherein: The IGBT temperature detection module comprises a thermistor RT2 and a capacitor C512, the heating wire disc temperature circuit comprises a heating wire disc surface temperature circuit and a heating wire disc temperature measurement circuit, the heating wire disc surface temperature circuit comprises a thermistor A01, a resistor R506 and an interface CON3, and the heating wire disc temperature measurement circuit comprises a thermistor RT1 and an interface CN1.
8. The medical ly freeze-dried tube thawing apparatus according to claim 1, wherein: The voltage detection module comprises a capacitor C200, a resistor R220, a resistor R221, a resistor R202, a resistor R222 and a resistor R223, and the current detection module is composed of a current detection sampling transformer CT1, a resistor R100, a capacitor C100, a capacitor C101, diodes D100-D103, a slide rheostat VR1 and a resistor R101.
9. The medical ly freeze-dried tube thawing apparatus according to claim 1, wherein: The fan driving circuit comprises a triode Q501, a resistor R509, a capacitor C515, a fan and an interface CN2.
10. The medical ly freeze-dried tube thawing apparatus according to claim 1, wherein: The power driving circuit comprises a chip U3D, triodes Q300 and Q301, resistors R300-R303 and a diode D300, the model of the chip U3D is LM339, the power driving circuit is connected with a master oscillation circuit, and the master oscillation circuit comprises a capacitor C4, an IGBT1 and an inductor L1.