Sample mixing device for biochemical immunity instrument

Abstract

The utility model discloses a sample mixing device for a biochemical immunity instrument, which comprises a mounting unit, a linear driving mechanism and a sample mixing mechanism, the linear driving mechanism and the sample mixing mechanism are arranged on the mounting unit, the sample mixing mechanism comprises a fixing structure, a mixing motor and an eccentric mixing assembly, and the fixing structure comprises a moving part driven by the linear driving mechanism. A motor base of the uniform mixing motor is fixedly connected to the moving part, the eccentric uniform mixing assembly comprises a uniform mixing base and a uniform mixing head used for containing a reaction cup, the uniform mixing head and the uniform mixing base are eccentrically arranged, and a motor shaft of the uniform mixing motor is fixedly connected with the lower portion of the uniform mixing base. According to the utility model, the linear driving mechanism is used for driving the sample mixing mechanism to linearly move back and forth, so that mixing and moving can be realized, the sample mixing efficiency is improved, the detection efficiency of a biochemical immunity instrument is further improved, and high-throughput detection is realized; according to the utility model, the blending motor is used as blending power, and the blending motor is fixedly connected with the blending seat, so that the eccentric movement of the blending head in the blending seat is effectively ensured, and the slipping phenomenon is avoided.

Description

Technical Field

[0001] This utility model relates to a biochemical immunoassay analyzer, and more particularly to a sample mixing device for a biochemical immunoassay analyzer. Background Technology

[0002] In immunoassay testing, sample and reagent pretreatment is typically required to ensure the components are fully mixed and blended to guarantee accurate results. Existing mixing devices are usually fixed-type, using a mechanical gripper to pick up reaction cups and place them in the device for mixing. After mixing, the gripper returns the cups to their designated positions. Each cup requires mixing and handling, resulting in low efficiency and failing to meet the high-throughput testing requirements of clinical biochemical and immunological assays. Therefore, designing a sample mixing device compatible with high-throughput biochemical and immunological instruments is crucial for improving the high-throughput capabilities of these instruments. Summary of the Invention

[0003] In view of this, the present invention proposes a sample mixing device for a biochemical immunoassay analyzer.

[0004] To achieve the above objectives, the present invention adopts the following technical solution:

[0005] The sample mixing device for a biochemical immunoassay analyzer described in this utility model includes an installation unit, a linear drive mechanism disposed on the installation unit, and a sample mixing mechanism driven by the linear drive mechanism. The sample mixing mechanism includes a fixed structure, a mixing motor, and an eccentric mixing assembly. The fixed structure includes a moving part driven by the linear drive mechanism. The motor base of the mixing motor is fixedly connected to the moving part. The eccentric mixing assembly includes a mixing seat and a mixing head for holding a reaction cup. The mixing head and the mixing seat are eccentrically arranged. The motor shaft of the mixing motor is fixedly connected to the lower part of the mixing seat.

[0006] The beneficial effects are: This utility model uses a linear drive mechanism to drive the sample mixing mechanism to move back and forth in a straight line, which can realize mixing and moving at the same time, improve the sample mixing efficiency, and thus improve the detection efficiency of the biochemical immunoassay analyzer, and realize high-throughput detection; This utility model uses a mixing motor as the mixing power, and the mixing motor and the mixing seat are fixedly connected, which effectively ensures the eccentric movement of the mixing head in the mixing seat and avoids slippage.

[0007] Preferably, the mounting unit includes a horizontally arranged first plate and a vertically arranged second plate on the first plate. The linear drive mechanism is fixedly connected to the first plate, and the moving part is connected to the second plate through a guide pair, so that the moving part moves back and forth in a straight line above the first plate, ensuring the straight back and forth movement of the sample mixing mechanism.

[0008] Preferably, the linear drive mechanism is any one of a belt drive mechanism, a lead screw motor, a cylinder, or an electric cylinder fixed to the first plate; the moving part is a vertically arranged moving plate, the lower part of which is connected to the linear power output end of the linear drive mechanism, so that the sample mixing mechanism moves back and forth in a straight line above the first plate, thereby achieving mixing while moving and improving the mixing effect.

[0009] Preferably, the linear drive mechanism is a belt drive mechanism, which includes a moving motor, a driving pulley, a driven pulley, and a synchronous belt. The lower part of the moving plate is fixedly connected to the synchronous belt via a clamping unit. In actual installation, the driving pulley and the driven pulley are spaced apart at both ends of the first plate, the synchronous belt is wound around the driving pulley and the driven pulley, the moving motor is connected to the driving pulley for transmission, and the synchronous belt can serve as a linear power output.

[0010] Preferably, the guide pair includes a slide rail mounted on the second plate and a slider that slides with the slide rail. The slider is fixed to the back of the moving part, and the slide rail is aligned with the length direction of the second plate. The beneficial effect is that this invention ensures the linear motion trajectory of the moving part through the slider and slide rail, avoiding deflection.

[0011] Preferably, the eccentric mixing assembly further includes a limiting unit for limiting the mixing head, the limiting unit including a limiting baffle disposed on the motor base and a limiting shaft disposed on the upper part of the limiting baffle, one end of the limiting shaft being fixedly connected to the mixing head.

[0012] Preferably, the limiting baffle is provided with a photoelectric switch for monitoring the original position of the mixing seat, and the mixing seat is provided with a trigger plate that cooperates with the photoelectric switch. In this invention, the photoelectric switch and the trigger plate cooperate to determine the initial position of the mixing seat.

[0013] Preferably, a position sensor is provided on the back of the moving part, and a sensing code tooth is provided on the second plate to cooperate with the position sensor. The sensing code tooth is located in the sensing groove of the position sensor. The position sensor and the sensing code tooth cooperate to determine the position of the sample mixing mechanism.

[0014] Compared with the prior art, this utility model uses a linear drive mechanism to drive the sample mixing mechanism to move back and forth in a straight line, which can realize mixing and moving at the same time, improve the sample mixing efficiency, and thus improve the detection efficiency of the biochemical immunoassay analyzer, and realize high-throughput detection. This utility model uses a mixing motor as the mixing power, and the mixing motor and the mixing seat are fixedly connected, which effectively ensures the eccentric movement of the mixing head in the mixing seat and avoids slippage. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model.

[0016] Figure 2 This is a schematic diagram of the present invention omitting the sample mixing mechanism.

[0017] Figure 3 This is a schematic diagram of the sample mixing mechanism described in this utility model.

[0018] Figure 4 This is a cross-sectional schematic diagram of the sample mixing mechanism described in this utility model.

[0019] Figure 5 This is a diagram showing the installation location of this utility model in a biochemical immunoassay analyzer. Detailed Implementation

[0020] The embodiments of this utility model will be described in detail below with reference to the accompanying drawings. These embodiments are implemented based on the technical solution of this utility model and provide detailed implementation methods and specific operation processes. However, the protection scope of this utility model is not limited to the following embodiments.

[0021] It should be noted that in the description of this utility model, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations.

[0022] In the description of this utility model, unless otherwise explicitly specified and limited, the terms "connected" and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0023] like Figure 1As shown, this utility model proposes a sample mixing device for a biochemical immunoassay analyzer, including an installation unit, a linear drive mechanism mounted on the installation unit, and a sample mixing mechanism driven by the linear drive mechanism. The sample mixing mechanism includes a fixed structure, a mixing motor 2, and an eccentric mixing assembly 3. The fixed structure includes a moving part (i.e., a vertically arranged moving plate 1.1) driven by the linear drive mechanism. The motor base 2a of the mixing motor 2 is fixedly connected to the moving plate 1.1. The eccentric mixing assembly 3 includes a mixing seat 3.1 and a mixing head 3.2 for holding a reaction cup. The mixing head 3.2 and the mixing seat 3.1 are eccentrically arranged. The motor shaft of the mixing motor 2 is fixedly connected to the lower part of the mixing seat 3.1. This invention utilizes a linear drive mechanism to drive the sample mixing mechanism to move back and forth in a linear motion. The mixing motor 2 drives the reaction cup inside the eccentric mixing assembly 3 to move eccentrically, achieving simultaneous mixing and movement, thereby improving the sample mixing efficiency and thus increasing the detection efficiency of the biochemical immunoassay analyzer, achieving high-throughput detection. In addition, the mixing motor 2 and the mixing seat 3.1 are fixedly connected, effectively ensuring the eccentric movement of the mixing head 3.2 inside the mixing seat 3.1 and avoiding slippage.

[0024] Combination Figure 1-2 It is understood that the installation unit includes a horizontally arranged first plate 4.1 and a vertically arranged second plate 4.2 on the first plate 4.1. A linear drive mechanism is fixedly connected to the first plate 4.1, and the moving part (i.e., the vertically arranged moving plate 1.1) is connected to the second plate 4.2 through a guide pair. The linear drive mechanism is a belt drive mechanism (of course, in actual installation, the linear drive mechanism can also be a linear power source such as a lead screw motor, cylinder, or electric cylinder fixedly connected to the first plate). It includes a moving motor 5.1, a driving pulley 5.2, a driven pulley 5.3, and a synchronous belt 5.4. The lower part of the moving plate 1.1 is fixedly connected to the synchronous belt 5.4 (i.e., the linear power output part) through a clamping unit. Among them, the driving pulley 5.2 and the driven pulley are spaced apart at both ends of the first plate 4.1, and the synchronous belt 5.4 is wound around the driving pulley 5.2 and the driven pulley. The moving motor 5.1 is connected to the driving pulley 5.2 and drives the moving plate 1.1 to move back and forth in a straight line through the synchronous belt 5.4, thereby realizing the straight back and forth movement of the sample mixing mechanism.

[0025] Combination Figure 1 It is understood that the installation unit also includes a column 4.3 and a horizontally arranged support plate 4.4, which can be installed on the frame of the biochemical immunoassay analyzer, thereby realizing the installation of this utility model on the biochemical immunoassay analyzer.

[0026] Combination Figure 2It is known that the clamping unit includes a first clamping plate 1.2 fixed to the lower part of the moving plate 1.1 and a second clamping plate fixed to the first clamping plate 1.2 (the second clamping plate and the first clamping plate are fixed together by bolts, and the synchronous belt 5.4 is located between the first clamping plate 1.2 and the second clamping plate). The first clamping plate 1.2 and the second clamping plate are used to realize the connection between the synchronous belt 5.4 and the moving plate 1.1, so as to ensure that the moving plate 1.1 moves synchronously during the movement of the synchronous belt 5.4.

[0027] Combination Figure 1-2 It can be seen that the guide pair includes a slide rail 5.5 mounted on the second plate 4.2 and a slider that slides with the slide rail 5.5. The slider is fixed to the back of the moving plate 1.1. The slide rail 5.5 is aligned with the length direction of the second plate 4.2. The slider and the slide rail 5.5 ensure the linear motion accuracy of the moving part and prevent the moving plate 1.1 from tilting up and down.

[0028] Combination Figure 3-4 It is understood that the eccentric mixing assembly 3 also includes a limiting unit for limiting the mixing head 3.2. The limiting unit includes a limiting baffle 3.3 disposed on the motor base 2a and a limiting shaft 3.4 disposed on the upper part of the limiting baffle 3.3. One end of the limiting shaft 3.4 is fixedly connected to the mixing head 3.2. The upper part of the mixing base 3.1 has an inclined mounting hole. The mixing head 3.2 is rotatably disposed in the mounting hole through a bearing 3.5. The mixing head 3.2 and the mounting hole are coaxially arranged. The motor shaft of the mixing motor 2 is coaxial with the mixing base 3.1. During operation, the mixing motor 2 provides power. Due to the eccentric design of the mixing head 3.2, the mixing head 3.2 makes conical motion around its axis under the combined action of the mixing motor 2 and the limiting shaft 3.4, thereby realizing the conical motion of the reaction cup.

[0029] Combination Figure 3-4 It is known that a photoelectric switch 3.6 for monitoring the original position of the mixing seat 3.1 is provided on the limiting baffle 3.3, and a trigger piece 3.7 that cooperates with the photoelectric switch 3.6 is provided on the mixing seat 3.1. The signal output terminal of the photoelectric switch 3.6 is connected to the control system of the biochemical immunoassay analyzer. When the trigger piece 3.7 passes the photoelectric switch, it triggers the photoelectric switch, determining the original position of the mixing seat 3.1. Each time mixing is started, the mixing seat is located at the original position, further ensuring the consistency of the mixing time of the reaction system in each reaction vessel.

[0030] Combination Figure 1 It is known that a position sensor is installed on the back of the moving plate 1.1, and a sensing code 6.1 that cooperates with the position sensor is installed on the second plate 4.2. The sensing code 6.1 is located in the sensing groove of the position sensor, and the signal output terminal of the position sensor is connected to the control system of the biochemical immunoassay analyzer. In actual operation, the position sensor can move synchronously with the moving plate 1.1. During the movement, the position sensor is triggered by the sensing code 6.1 to determine the Y-axis position of the sample mixing mechanism. Combined with... Figure 1 It is known that a primary position sensor 6.2 (preferably a photoelectric switch) is provided at one end of the second plate 4.2, and a metal piece 6.3 for triggering the primary position sensor is fixedly connected to the upper part of the moving plate 1.1. The signal output terminal of the primary position sensor 6.2 is connected to the control system of the biochemical immunoassay analyzer. When the moving plate 1.1 moves to the primary position, the metal piece 6.3 is located inside the primary position sensor 6.2 and triggers it, thus determining the primary position of the moving plate 1.1. The primary position sensor 6.2 and the position sensor together determine the specific position of the moving plate in the Y direction, and thus determine the specific position of the sample mixing mechanism.

[0031] This invention features a Y-axis mounting design on a biochemical immunoassay analyzer. It can be mounted Y-axis onto the analyzer's frame and is positioned between the sample loading mechanism F1 and the reagent loading mechanism F2. The analyzer also includes a reaction cup supply mechanism F3 and a reaction cup gripper mechanism that can move X-axis. See details below. Figure 5 During operation, the linear drive mechanism moves the sample mixing mechanism below the reaction cup gripper mechanism, which then places the reaction cup inside the mixing head 3.2. After receiving the reaction cup, the linear drive mechanism moves the sample mixing mechanism below the sample dispensing mechanism F1, which quantitatively adds the sample into the reaction cup F5. Then, it moves to the bottom of the reagent dispensing mechanism F2, which adds reagents into the reaction cup F5.

[0032] After the reagents are added, the mixing motor 2 is started. The mixing stepper motor drives the mixing seat 3.1 to rotate, which in turn drives the bottom of the reaction cup to perform eccentric tilting vortex oscillation mixing. While mixing, it moves to the reaction cup transfer station, realizing mixing and moving at the same time, improving the sample mixing efficiency, and thus improving the detection efficiency of the biochemical immunoassay analyzer.

[0033] Finally, it should be emphasized that the above description is merely a preferred embodiment of this utility model and is not intended to limit this utility model. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still make modifications to the technical solutions described in the foregoing embodiments without creative effort, or make equivalent substitutions for some of the technical features. Therefore, any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A sample mixing device for a biochemical immunoassay analyzer, comprising a mounting unit, a linear drive mechanism disposed on the mounting unit, and a sample mixing mechanism driven by the linear drive mechanism, characterized in that: The sample mixing mechanism includes a fixed structure, a mixing motor, and an eccentric mixing assembly. The fixed structure includes a moving part driven by the linear drive mechanism. The motor base of the mixing motor is fixedly connected to the moving part. The eccentric mixing assembly includes a mixing seat and a mixing head for holding a reaction cup. The mixing head and the mixing seat are eccentrically arranged. The motor shaft of the mixing motor is fixedly connected to the lower part of the mixing seat.

2. The sample mixing device for a biochemical immunoassay analyzer according to claim 1, characterized in that: The mounting unit includes a horizontally arranged first plate and a vertically arranged second plate on the first plate. The linear drive mechanism is fixedly connected to the first plate, and the moving part is connected to the second plate through a guide pair.

3. The sample mixing device for a biochemical immunoassay analyzer according to claim 2, characterized in that: The linear drive mechanism is any one of a belt drive mechanism, a lead screw motor, a pneumatic cylinder, or an electric cylinder that is fixed to the first plate; the moving part is a vertically arranged moving plate, the lower part of which is connected to the linear power output end of the linear drive mechanism, so that the sample mixing mechanism moves back and forth linearly above the first plate.

4. The sample mixing device for a biochemical immunoassay analyzer according to claim 3, characterized in that: The linear drive mechanism is a belt drive mechanism, which includes a moving motor, a driving pulley, a driven pulley, and a synchronous belt. The lower part of the moving plate is fixedly connected to the synchronous belt through a clamping unit.

5. The sample mixing device for a biochemical immunoassay analyzer according to claim 2, characterized in that: The guide pair includes a slide rail mounted on the second plate and a slider that slides with the slide rail. The slider is fixed to the back of the moving part, and the slide rail is aligned with the length direction of the second plate.

6. The sample mixing device for a biochemical immunoassay analyzer according to claim 1, characterized in that: The eccentric mixing assembly further includes a limiting unit for limiting the mixing head. The limiting unit includes a limiting baffle disposed on the motor base and a limiting shaft disposed on the upper part of the limiting baffle. One end of the limiting shaft is fixedly connected to the mixing head.

7. The sample mixing device for a biochemical immunoassay analyzer according to claim 6, characterized in that: The limiting baffle is provided with a photoelectric switch for monitoring the original position of the mixing seat, and the mixing seat is provided with a trigger piece that cooperates with the photoelectric switch.

8. The sample mixing device for a biochemical immunoassay analyzer according to claim 5, characterized in that: A position sensor is provided on the back of the moving part, and a sensing code tooth is provided on the second plate to cooperate with the position sensor. The sensing code tooth is located in the sensing groove of the position sensor.

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