Cell culture pore plate capable of being disassembled and combined

Abstract

The utility model provides a detachable combined cell culture pore plate which comprises a base, the upper surface of the base is provided with a plurality of first placing grooves, the first placing grooves can be internally provided with combined unit cell holes, the combined unit cell holes comprise two-hole combined unit cell holes, four-hole combined unit cell holes and six-hole combined unit cell holes, and the first placing grooves and the second placing grooves are formed in the base. A second placement groove is further formed in the base, a drawer is slidably connected in the second placement groove, and a disinfection lamp which is located in the second placement groove and can move left and right is arranged above the drawer. Compared with the prior art, the cell culture pore plate has the following beneficial effects that the cell culture pore plate can be arranged into assembly cell pores with different specifications, so that the assembly cell pores with different specifications can be matched for use, the requirements of various experiment combinations can be met, and unnecessary waste is reduced; a handle is arranged on the side surface of the slide, so that a worker can conveniently take the slide; the disinfection lamp can be driven to move left and right through the driving cylinder.

Description

Technical Field

[0001] This utility model relates to the field of cell culture plate technology, and in particular to a detachable and combinable cell culture plate. Background Technology

[0002] With the development of biological sciences such as cell biology, molecular biology, and immunology, cell culture has become a common method in cell biology research. In vitro cell culture allows for targeted and selective control of the cell growth environment, making different types and sizes of cell culture plates particularly important. Currently, the most commonly used multi-well plates on the market are 6-well, 12-well, and 24-well plates. In actual cell culture work, researchers design positive controls, negative controls, and experimental groups according to their experimental protocols. For example, if a 24-well plate is required, but three groups are actually set up with replicates for each group, requiring a total of six wells, then 18 wells will be left unused. If these three groups of cells cannot be cultured simultaneously on the same plate, even more resources will be wasted. Some special experiments involve plate coating using slides. Currently, slides are made of glass, which is thin and fragile. They need to be removed with tweezers or other small tools; if sterilization is not thorough or if the slides come into contact with the skin, contamination can occur, affecting aseptic cell culture.

[0003] Existing cell culture plates cannot be disassembled and used individually, leading to excessive waste of consumables. Even if the remaining plates are processed and used for subsequent experiments, the risk of contamination will increase. Some special experiments require the use of slides, but the glass discs are small and thin, making them difficult to remove. Furthermore, existing cell culture plates do not have a sterilization component. Utility Model Content

[0004] In view of the shortcomings of the prior art described above, the purpose of this utility model is to provide a detachable and combinable cell culture plate to solve the problem that cell culture plates in the prior art cannot be disassembled and used independently, resulting in excessive waste of consumables.

[0005] To achieve the above and other related objectives, this utility model provides the following technical solution:

[0006] A detachable and combinable cell culture plate includes a base. The upper surface of the base has several first placement slots, each containing a cell well assembly. These cell well assemblies include 2-well, 4-well, and 6-well cell well assemblies. The base also has a second placement slot, within which a drawer is slidably connected. Above the drawer is a sterilization lamp located within the second placement slot and capable of left-right movement. This technical solution, by configuring the cell culture plate with cell well assemblies of different sizes, allows for the combined use of different sizes of cell well assemblies, addressing the needs of various experimental combinations and reducing unnecessary waste.

[0007] In one embodiment of the present invention, the upper surface of the base may be provided with a cover plate for covering the cell pores of the assembly, and the individual cell culture pores of the assembly may also be provided with a pore cover.

[0008] In one embodiment of the present invention, a plate connector is provided between two adjacent cell culture wells of the assembly cell well, and the assembly cell well is installed in the first placement groove via an attachment lug.

[0009] In one embodiment of the present invention, each cell culture well of the cell pores of the assembly may be provided with a climbing plate, and the climbing plate is provided with a handle for easy picking up. The climbing plate in this technical solution is provided with a handle, which makes it convenient for staff to pick up the climbing plate.

[0010] In one embodiment of the present invention, the drawer is provided with a plurality of partitions, which divide the drawer into a plurality of third placement slots for placing the cell pores of the assembly.

[0011] In one embodiment of the present invention, a drive cylinder for driving the disinfection lamp to move left and right is installed on the top side of the second placement slot, and the disinfection lamp is mounted on the drive cylinder by a mounting plate and is located above the third placement slot.

[0012] In one embodiment of the present invention, a sliding rod located on the side of the disinfection lamp is also installed on the top side of the second placement groove by means of a fixing block, and a sliding sleeve connected to the mounting plate is slidably connected to the surface of the sliding rod.

[0013] The above technical solution uses a drive cylinder to move the disinfection lamp left and right, and the sliding sleeve on the slide rod makes the movement of the disinfection lamp more stable, so that the disinfection lamp can disinfect the items in the drawer.

[0014] As described above, the detachable and combinable cell culture plate of this invention has the following beneficial effects:

[0015] This invention allows cell culture plates to be configured with cell wells of different specifications, enabling the use of various combinations of cell wells to meet the needs of different experimental setups and reduce unnecessary waste. A handle is provided on the side of the plate for easy handling by staff. A drive cylinder enables the sterilization lamp to move left and right, and the sliding sleeve on the slide rod ensures stable movement of the lamp. The sterilization lamp can sterilize items in drawers, facilitating its widespread adoption and use. Attached Figure Description

[0016] Figure 1 This is a top view schematic diagram of the detachable and combinable cell culture plate disclosed in the embodiments of this utility model;

[0017] Figure 2 This is a frontal perspective three-dimensional schematic diagram of the cell pores of the detachable and combinable cell culture plate disclosed in the embodiments of this utility model;

[0018] Figure 3 This is a frontal perspective three-dimensional schematic diagram of the detachable and combinable cell culture plate and handle disclosed in the embodiments of this utility model;

[0019] Figure 4 This is a right-side view of the base in the detachable and combinable cell culture plate disclosed in this embodiment of the present invention.

[0020] Figure 5 This is a top view of the drawer in the detachable and combinable cell culture plate disclosed in this embodiment of the present invention;

[0021] Figure 6 This is a bottom view of the drive cylinder and sterilization lamp in the detachable and combinable cell culture plate disclosed in this embodiment of the present invention.

[0022] Component designation explanation

[0023] 1. Base; 2. First placement slot; 3. Assembly cell hole; 301. Assembly cell hole with 2 holes; 302. Assembly cell hole with 4 holes; 303. Assembly cell hole with 6 holes; 4. Cover plate; 5. Orifice plate connector; 6. Attached ear; 7. Climbing plate; 8. Handle; 9. Second placement slot; 10. Drawer; 11. Partition; 12. Third placement slot; 13. Drive cylinder; 14. Mounting plate; 15. Disinfection lamp; 16. Fixing block; 17. Slide rod; 18. Slide sleeve. Detailed Implementation

[0024] The following specific embodiments illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification. It should be noted that, unless otherwise specified, the following embodiments and features can be combined with each other.

[0025] Please see Figure 1 This utility model provides a detachable and combinable cell culture plate, including a base 1. The upper surface of the base 1 is provided with a plurality of first placement slots 2. The first placement slots 2 can be provided with assembly cell wells 3. The assembly cell wells 3 include 2-well assembly cell wells 301, 4-well assembly cell wells 302 and 6-well assembly cell wells 303. By setting the cell culture plate with assembly cell wells 3 of different specifications, the assembly cell wells 3 of different specifications can be used in combination, which can solve the needs of various experimental combinations and reduce unnecessary waste.

[0026] exist Figures 1 to 3 In this embodiment, the upper surface of the base 1 may be provided with a cover plate 4 for covering the cell culture wells 3 of the assembly, and a cover may also be provided on each individual cell culture well of the cell culture wells 3 of the assembly. In this embodiment, the base 1 is composed of 24 horizontal and vertical partitions with a smooth transparent bottom plate. After the cover plate 4 is placed on it, it is in a sealed state. The notch at the upper left corner of the cover plate 4 is to facilitate the determination of the left and right positions of the cover plate 4 when placing it. In addition, one or more interconnected cover plates may be provided according to the specifications of the cell culture wells. A well plate connector 5 is provided between two adjacent cell culture wells of the cell culture wells 3 of the assembly, and the cell culture wells 3 of the assembly are installed in the first placement groove 2 through the lugs 6. Each cell culture well of the cell culture wells 3 of the assembly may be provided with a climbing plate 7. The climbing plate 7 is provided with a handle 8 for easy picking up the climbing plate 7. In this embodiment, the climbing plate 7 is made of polypropylene. By providing a handle 8 on the climbing plate 7, it is convenient for the staff to pick up the climbing plate 7.

[0027] exist Figures 4 to 6In the base 1, a second placement slot 9 is provided, and a drawer 10 is slidably connected within the second placement slot 9. The drawer 10 has several partitions 11, which divide the drawer 10 into several third placement slots 12 for placing the cell pores 3 of the assembly. Above the drawer 10 is a disinfection lamp 15 located within the second placement slot 9 and capable of moving left and right. A drive cylinder 13 is installed on the top side of the second placement slot 9 to drive the disinfection lamp 15 to move left and right. The drive cylinder 13 is a magnetic coupler rodless cylinder. The disinfection lamp 15 is mounted on the drive cylinder 13 via the mounting plate 14 and is located above the third placement slot 12. The top side of the second placement slot 9 is also mounted with a sliding rod 17 located on the side of the disinfection lamp 15 via a fixing block 16. The surface of the sliding rod 17 is slidably connected to a sliding sleeve 18 connected to the mounting plate 14. The drive cylinder 13 can drive the disinfection lamp 15 to move left and right. With the cooperation of the sliding sleeve 18 sliding on the sliding rod 17, the movement of the disinfection lamp 15 can be made more stable. The disinfection lamp 15 can disinfect the items in the drawer 10.

[0028] Specifically, when using the detachable and combinable cell culture plate, first remove the base 1, select the appropriate size of the combinable cell well 3, and then install the combinable cell well 3 on the base 1 through the lugs 6. Simply add cell suspension and appropriate culture medium to the required cell culture wells, and then place the climbing slide 7 and close the cover plate 4. After the experiment is completed, the combinable cell well 3 that needs to be sterilized can be placed in the third placement slot 12, and then the sterilization lamp 15 can be moved left and right under the drive of the drive cylinder 13, so as to sterilize the combinable cell well 3 in the drawer 10. In practical applications, because the sterilization lamp 15 can damage the cells when it is turned on, it cannot be used after cell inoculation. Therefore, the sterilization lamp 15 can be used to sterilize the equipment before inoculation.

[0029] More specifically, this invention can design 6-well, 12-well, and 24-well plates of different specifications based on existing culture plates. It can also design combined specifications (such as 2-well, 4-well, and 6-well plates integrated) as needed, with both even and even numbers of wells. Therefore, this invention is suitable for cell culture plates used in adherent and suspension cultures. It can be arbitrarily disassembled and combined for use, with appropriate accessories selected according to needs and experimental objectives, making it simple and convenient. Compared with existing technologies, this invention has a simple structure, is easy to operate, has low cost, can be mass-produced, has low loss, and can be used multiple times. It can be freely combined, with appropriate combinations of well plates selected according to the design. It is clean and hygienic, avoiding contamination. Different specifications of combined well molds can also be developed to produce disposable consumables, which are inexpensive, easy to operate, save reagents, consumables, and culture media, are convenient to handle, and promote cell growth.

[0030] In summary, this invention enables cell culture plates to be configured with cell wells 3 of different specifications, allowing for the combined use of cell wells 3 of different specifications, thus meeting the needs of various experimental combinations and reducing unnecessary waste. Furthermore, a handle 8 is provided on the side of the slide 7, making it easy for staff to pick up and use the slide 7. The drive cylinder 13 can move the sterilization lamp 15 left and right, and the sliding sleeve 18, in conjunction with the sliding rod 17, ensures more stable movement of the sterilization lamp 15. The sterilization lamp 15 can sterilize items in the drawer 10, facilitating its promotion and use.

[0031] The above embodiments are merely illustrative of the principles and effects of this utility model and are not intended to limit this utility model. All equivalent modifications or alterations made by those skilled in the art without departing from the spirit and technical concept disclosed in this utility model should still be covered by the claims of this utility model.

Claims

1. A detachable and combinable cell culture plate, comprising a base (1), characterized in that: The upper surface of the base (1) is provided with a plurality of first placement slots (2), and the first placement slots (2) may be provided with assembly cell pores (3). The assembly cell pores (3) include 2-hole assembly cell pores (301), 4-hole assembly cell pores (302) and 6-hole assembly cell pores (303). A well plate connector (5) is provided between two adjacent cell culture wells of the assembly cell pores (3), and the assembly cell pores (3) are installed in the first placement slots (2) by means of lugs (6). Each cell culture well of the assembly cell pores (3) may be provided with a climbing plate (7), and the climbing plate (7) is provided with a handle (8) for easy picking up the climbing plate (7). The base (1) is also provided with a second placement slot (9), and a drawer (10) is slidably connected in the second placement slot (9). Above the drawer (10) is a disinfection lamp (15) located in the second placement slot (9) and capable of moving left and right.

2. The detachable and combinable cell culture plate according to claim 1, characterized in that: The upper surface of the base (1) may be provided with a cover plate (4) for covering the cell pores (3) of the assembly, and a pore cover may also be provided on the individual cell culture pores (3) of the assembly.

3. The detachable and combinable cell culture plate according to claim 1, characterized in that: The drawer (10) is provided with a plurality of partitions (11), which divide the drawer (10) into a plurality of third placement slots (12) for placing the assembly cell pores (3).

4. A detachable and combinable cell culture plate according to claim 3, characterized in that: The top side of the second placement slot (9) is equipped with a drive cylinder (13) for driving the disinfection lamp (15) to move left and right. The disinfection lamp (15) is mounted on the drive cylinder (13) via a mounting plate (14) and is located above the third placement slot (12).

5. A detachable and combinable cell culture plate according to claim 4, characterized in that: The top side of the second placement slot (9) is also equipped with a slide rod (17) located on the side of the disinfection lamp (15) via a fixing block (16), and the surface of the slide rod (17) is slidably connected to a sliding sleeve (18) connected to the mounting plate (14).

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