Blood coagulation analyzer

Abstract

The utility model discloses a blood coagulation analyzer which comprises a test block main body, the top surface of the test block main body is provided with a first reaction tank for placing a reaction cup, and the side surface of the test block main body is provided with a first light source tank, a second light source tank, a first receiving tank and a second receiving tank; the second emitting light source is mounted in the second light source groove; a first light beam emitted by the first emission light source and a second light beam emitted by the second emission light source have different wavelengths; the first circuit board is mounted in the first receiving groove and is used for receiving a first optical signal formed after the first light beam is acted by a sample in the reaction cup; the second circuit board is mounted in the second receiving groove and is used for receiving a second light signal formed after the second light beam is acted by a sample in the reaction cup. According to the technical scheme, two light sources with different wavelengths are arranged on the same test channel, the light sources with different wavelengths are selected for detection according to actual needs, multi-item detection is further achieved, and meanwhile the structure is simple, manufacturing is facilitated, and cost is saved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of modern medical technology, especially relates to a blood coagulation analyzer. BACKGROUND

[0002] Blood coagulation analyzer is the clinical necessary in-vitro detection equipment, mainly for the risk assessment of trauma operation and the diagnosis and prevention and treatment of cardiovascular and cerebrovascular diseases.

[0003] The commonly used detection method of blood coagulation analyzer has optical method, and the optical method is to determine the parameters of plasma according to the turbidity change in the plasma coagulation process, that is, to determine the parameters according to the absorbance change of the sample to be measured in the coagulation process. The optical method detection has the advantages of high sensitivity, simple instrument structure and easy automation.

[0004] However, the existing blood coagulation analyzer using optical method detection basically adopts single-channel single-light source mode, and the structure is complex. UTILITY MODEL CONTENT

[0005] Therefore, the utility model provides a blood coagulation analyzer, sets up two different wavelength light sources on the same test channel, and realizes the detection of multiple items, and the structure is simple and the cost is low.

[0006] In order to achieve the above purpose, the utility model provides the following technical scheme:

[0007] A blood coagulation analyzer, comprising:

[0008] A test block main body, a first reaction groove for placing a reaction cup is formed on the top surface of the test block main body, a first light source groove, a second light source groove, a first receiving groove and a second receiving groove are formed on the side surface of the test block main body, wherein the first light source groove, the second light source groove, the first receiving groove and the second receiving groove are all in communication with the first reaction groove;

[0009] A first emitting light source is installed in the first light source groove;

[0010] A second emitting light source is installed in the second light source groove;

[0011] The wavelength of the first light beam emitted by the first emitting light source is different from the wavelength of the second light beam emitted by the second emitting light source;

[0012] A first circuit board is installed in the first receiving groove for receiving the first optical signal formed after the first light beam is affected by the sample in the reaction cup;

[0013] A second circuit board is installed in the second receiving groove for receiving the second optical signal formed after the second light beam is affected by the sample in the reaction cup.

[0014] Preferably, the wavelength of the first light beam emitted by the first emitting light source is 405 nm, and the wavelength of the second light beam emitted by the second emitting light source is 660 nm.

[0015] Preferably, the upper part of the first emitting light source is sleeved in the first light source groove through a first lamp sleeve, and the lower part of the first emitting light source is installed in the first light source groove through the first O-ring.

[0016] Preferably, the emitting end of the first emitting light source is provided with a light transmission hole, and the light transmission hole is installed with a 405 nm filter.

[0017] Preferably, the material of the test block body is aluminum alloy 6061, and the surface thereof is subjected to black anodic oxidation treatment.

[0018] Preferably, the third emitting light source and the third circuit board are further included.

[0019] The top surface of the test block body is further provided with a third reaction groove for placing the reaction cup, and the side surface of the test block body is further provided with a third light source groove and a third receiving groove, both of which are in communication with the third reaction groove.

[0020] The third emitting light source is installed in the third light source groove.

[0021] The third circuit board is installed in the third receiving groove for receiving a third light signal formed by the third light beam emitted by the third emitting light source after being acted on by the sample in the reaction cup.

[0022] The wavelength of the third light beam emitted by the third emitting light source is 660 nm.

[0023] Preferably, the photovoltaic cell of the first circuit board is installed in the first receiving groove for receiving the first light signal.

[0024] The photovoltaic cell of the second circuit board is installed in the second receiving groove for receiving the second light signal.

[0025] The photovoltaic cell of the third circuit board is installed in the third receiving groove for receiving the third light signal.

[0026] Preferably, the axis of the first light source groove and the axis of the first receiving groove are collinear.

[0027] The axis of the second light source groove and the axis of the second receiving groove are collinear.

[0028] The axis of the third light source groove and the axis of the third receiving groove are collinear.

[0029] Preferably, the test block body is a polyhedron.

[0030] The first light source groove, the second light source groove, the third light source groove, the first receiving groove, the second receiving groove and the third receiving groove are respectively arranged on different sides of the test block body.

[0031] Preferably, the test block body further comprises a first tension spring and a second tension spring.

[0032] The top surface of the test block body is further provided with a first placing groove, which is communicated with the top of the first reaction groove, and the first tension spring is installed in the first placing groove and used to elastically press a side wall of the reaction cup in the radial direction so as to fix the reaction cup.

[0033] The top surface of the test block body is further provided with a second placing groove, which is communicated with the top of the third reaction groove, and the second tension spring is installed in the second placing groove and used to elastically press a side wall of the reaction cup in the radial direction so as to fix the reaction cup.

[0034] As can be seen from the above technical solution, the coagulation analyzer provided by the present application is provided with two light sources with different wavelengths on the same test channel, and different wavelengths of light sources can be selected for detection according to actual needs, so that multi-item detection can be realized, and the structure is simple, which is beneficial to manufacturing and cost saving. BRIEF DESCRIPTION OF DRAWINGS

[0035] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed to be used in the embodiments or prior art description will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative labor on the basis of these drawings.

[0036] Figure 1 The axial measurement structure schematic diagram of the coagulation analyzer provided by the embodiments of the present application;

[0037] Figure 2 The A-A perspective view of the coagulation analyzer provided by the embodiments of the present application; Figure 1

[0038] The meanings of various reference signs in the drawings are as follows:

[0039] ​1 is a test block main body, 11 is a first reaction tank, 12 is a first light source tank, 13 is a second light source tank, 14 is a first receiving tank, 15 is a second receiving tank, 16 is a first lamp sleeve, 17 is a first O-shaped ring, 18 is a 405nm filter, 19 is a third reaction tank, 110 is a third light source tank, 111 is a third receiving tank, 112 is a first placing tank, 113 is a second placing tank, and 114 is a photocell isolation ring.

[0040] 2 is a reaction cup; 3 is a first emitting light source; 4 is a second emitting light source; 5 is a first circuit board; 6 is a second circuit board; 7 is a third emitting light source; 8 is a third circuit board; 9 is a first tension spring; and 10 is a second tension spring. DETAILED DESCRIPTION

[0041] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0042] The coagulation analyzer provided in the embodiments of the utility model, as shown in Figure 1 and Figure 2 , comprises:

[0043] A test block main body 1 is provided with a first reaction tank 11 for placing a reaction cup 2 on the top surface, and a first light source tank 12, a second light source tank 13, a first receiving tank 14 and a second receiving tank 15 are arranged on the side surface, wherein the first light source tank 12, the second light source tank 13, the first receiving tank 14 and the second receiving tank 15 are all in communication with the first reaction tank 11, and the first light source tank 12, the second light source tank 13, the first receiving tank 14, the second receiving tank 15 and the first reaction tank 11 form a test channel;

[0044] A first emitting light source 3 is installed in the first light source tank 12;

[0045] A second emitting light source 4 is installed in the second light source tank 13;

[0046] The first light beam emitted by the first emitting light source 3 and the second light beam emitted by the second emitting light source 4 are different in wavelength;

[0047] A first circuit board 5 is installed in the first receiving tank 14 and used for receiving a first optical signal formed after the first light beam is affected by a sample in the reaction cup 2;

[0048] The second circuit board 6 is installed in the second receiving groove 15 and is used for receiving a second light signal formed by the second light beam after the sample in the reaction cup 2 is acted on.

[0049] In the technical solution, two light sources with different wavelengths are arranged on the same test channel, and different wavelengths of light sources are selected for detection according to actual needs, so that the detection efficiency is improved, and the needs of coagulation method, chromogenic substrate method and immunoturbidimetry detection items are met, and the structure is simple, which is beneficial to manufacturing and cost saving.

[0050] It should be noted that the basic principle of the above technical solution is that the light beam can penetrate the reaction cup 2, the sample to be measured and the reagent are placed in the reaction cup 2, the change of the optical characteristics of the reaction system in the process is continuously monitored, the signal change received on the circuit board before and after the reaction of the sample to be measured is processed, and the coagulation and anticoagulation, fibrinolysis and antifibrinolysis functions of the plasma are detected through a specific algorithm.

[0051] In an alternative implementation, the wavelength of the first light beam emitted by the first emitting light source 3 is 405 nm, and the wavelength of the second light beam emitted by the second emitting light source 4 is 660 nm. In the technical solution, different wavelengths can realize the detection of different items, wherein 405 nm is mainly used for chromogenic substrate method detection items, and 660 nm is mainly used for coagulation method and immunoturbidimetry detection items. As a preferred embodiment, the first emitting light source 3 and the second emitting light source 4 are both LED lamps.

[0052] The above technical solution is optimized as shown in Figures 1-2 In order to ensure the accuracy of the measurement and the stability of the test process, the upper part of the first emitting light source 3 is sleeved in the first light source groove 12 by the first lamp sleeve 16, and the lower part of the first emitting light source 3 is installed in the first light source groove by the first O-shaped ring 17. As a preferred embodiment, the upper part of the second emitting light source 4 is sleeved in the second light source groove 13 by the second lamp sleeve, and the lower part of the second emitting light source 4 is installed in the second light source groove 13 by the second O-shaped ring. In addition, the arrangement of the lamp sleeve can realize the detachable assembly of the emitting light source and the light source groove, so as to meet the replacement of different wavelength light sources.

[0053] The above technical solution is further optimized, and the emitting end of the first emitting light source 3 is provided with a light transmission hole, the light transmission hole is provided with a 405 nm filter 18, the 405 nm filter 18 allows light with a specific wavelength of 405 nm to pass through, blocks or reflects light with other wavelengths, reduces external light source interference, improves the purity of the light source, and reduces data acquisition errors.

[0054] In a possible embodiment, the material of the test block body 1 is aluminum alloy 6061, and the surface thereof is treated by black anodization, so that temperature changes can be effectively eliminated, and the accuracy of the coagulation analyzer can reach a higher level. It should be noted that the aluminum alloy has the characteristics of fast heat conduction speed and high heat conduction efficiency, and the test block can be preheated to 37°C during the test process. The aluminum alloy test block can effectively eliminate temperature changes, reduce the influence of external temperature on the LED, and avoid changes in the light intensity of the LED itself during the test process. At the same time, the surface of the aluminum alloy test block is treated by black anodization by taking advantage of the characteristics of black light absorption and low reflectivity, so as to reduce the interference of reflected light on the photovoltaic cells on the LED signal receiving circuit board, and improve the data acquisition accuracy during the test process.

[0055] In a possible embodiment, as shown in Figure 1 and Figure 2 , the third light source 7 and the third circuit board 8 are further included.

[0056] The top surface of the test block body 1 is further provided with a third reaction groove 19 for placing the reaction cup 2, and the side surface of the test block body 1 is further provided with a third light source groove 110 and a third receiving groove 111, both of which are in communication with the third reaction groove 19. The third light source groove 110, the third receiving groove 111, and the third reaction groove 19 constitute another test channel.

[0057] The third light source 7 is installed in the third light source groove 110.

[0058] The third circuit board 8 is installed in the third receiving groove 111, and is used for receiving the third light signal formed by the third light beam emitted by the third light source 7 after being affected by the sample in the reaction cup 2.

[0059] The wavelength of the third light beam emitted by the third light source 7 is 660 nm.

[0060] In the technical solution, three light sources with different wavelengths are provided to support the detection function of two test channels. One test channel uses two light sources with different wavelengths to support the detection of multiple coagulation items. The third light source 7 and the third circuit board 8 can be used to simultaneously test multiple items, which is beneficial to improve the test efficiency.

[0061] The above technical solution is optimized, and the photovoltaic cell of the first circuit board 5 is installed in the first receiving groove 14, and is used for receiving the first light signal.

[0062] The photovoltaic cell of the second circuit board 6 is installed in the second receiving groove 15, and is used for receiving the second light signal.

[0063] The photovoltaic cell of the third circuit board 8 is installed in the third receiving groove 111, and is used for receiving the third light signal.

[0064] In the above technical solution, the photocell is an element capable of generating electromotive force under the irradiation of light, and the photocell is a process product, which is conducive to reducing the price of the blood coagulation analyzer. It should be noted that the photocell converts the received signal through a specific algorithm to detect the coagulation and anticoagulation, fibrinolysis and antifibrinolysis functions of the blood plasma. As preferred, the photocell is installed in the receiving groove through the photocell spacer ring 114.

[0065] Optimize the above technical solution, in order to ensure the smoothness of the light beam, the axis of the first light source groove 12 and the axis of the first receiving groove 14 are collinear;

[0066] The axis of the second light source groove 13 and the axis of the second receiving groove 15 are collinear;

[0067] The axis of the third light source groove 110 and the axis of the third receiving groove 111 are collinear.

[0068] In the above technical solution, the arrangement makes the detection structure of the blood coagulation analyzer more reasonable.

[0069] Optimize the above technical solution, the test block body 1 is a polyhedron;

[0070] The first light source groove 12, the second light source groove 13, the third light source groove 110, the first receiving groove 14, the second receiving groove 15 and the third receiving groove 111 are respectively opened on different side surfaces of the test block body 1. In the above technical solution, the polyhedron is arranged to open different grooves on different side surfaces, so that the structure of the blood coagulation analyzer is arranged reasonably and simply.

[0071] Optimize the above technical solution, further comprising: a first tension spring 9 and a second tension spring 10;

[0072] The test block body 1 top surface is also provided with a first placing groove 112, which is communicated with the top of the first reaction groove 11. After the first tension spring 9 is installed in the first placing groove 112, it is used to elastically compress the side wall of a reaction cup 2 along the radial direction, so as to fix the reaction cup 2.

[0073] The test block body 1 top surface is also provided with a second placing groove 113, which is communicated with the top of the third reaction groove 19. After the second tension spring 10 is installed in the second placing groove 113, it is used to elastically compress the side wall of another reaction cup 2 along the radial direction, so as to fix the reaction cup 2.

[0074] In the above technical solution, the reaction cup 2 is fixed by the tension spring, which effectively prevents the influence of mechanical vibration and other factors on the measurement, so as to improve the detection accuracy.

[0075] In an embodiment, the test block body 1 is provided with a wire slot, which facilitates the wiring and fixing of the circuit wire harness and reduces the length of the data acquisition wire harness, thereby reducing the interference of the external environment during data acquisition.

[0076] The technical features mentioned above, the technical features to be mentioned below, and the technical features shown in the drawings alone can be combined with each other arbitrarily, as long as the combined technical features are not contradictory to each other. All feasible combinations of features are explicitly described herein. Any one of the multiple sub-features included in the same sentence can be applied independently, and does not have to be applied together with other sub-features.

[0077] The present solution will be further described below in combination with specific embodiments:

[0078] Advantages of the present technical solution:

[0079] Firstly, the coagulation analyzer can cover the detection items of the coagulation optical method, and one test channel can meet the light source used for the coagulation detection items. The coagulation analyzer has simple structure, high integration, fast detection speed, low price, and can meet the application of various coagulation test systems.

[0080] Secondly, the coagulation analyzer uses 405nm and 660nm light sources, both of which are LED cold light sources. The LED cold light sources have long service life, low power consumption, fast response speed, compact structure, no heating phenomenon, and better reliability.

[0081] Thirdly, the coagulation analyzer can switch the light source during use, and can detect the sample at the same time, thereby improving the detection speed and accuracy and the detection efficiency.

[0082] Fourthly, the coagulation analyzer is designed with a stop structure (i.e. a tension spring), which can prevent the change of the test result value caused by vibration during the test process after the reaction cup is put in, and improve the accuracy of the test result and the stability of the test process.

[0083] The embodiments in the specification are described in a progressive manner, and each embodiment focuses on the difference from other embodiments. The same or similar parts of each embodiment can be referred to each other.

[0084] The above description of the disclosed embodiments enables a person skilled in the art to implement or use the present application. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application should not be limited to the embodiments shown herein, but should be consistent with the widest scope of principles and novel features disclosed herein.

Claims

1. A coagulation analyzer, characterized by, The utility model relates to a test block, which comprises: a test block body (1) having a first reaction groove (11) on the top surface for placing a reaction cup (2), a first light source groove (12), a second light source groove (13), a first receiving groove (14) and a second receiving groove (15) on the side surface, wherein the first light source groove (12), the second light source groove (13), the first receiving groove (14) and the second receiving groove (15) are all in communication with the first reaction groove (11); a first emitting light source (3) installed in the first light source groove (12); a second emitting light source (4) installed in the second light source groove (13); the first light beam emitted by the first emitting light source (3) and the second light beam emitted by the second emitting light source (4) have different wavelengths; a first circuit board (5) installed in the first receiving groove (14) for receiving a first light signal formed by the first light beam after the action of a sample in the reaction cup (2); a second circuit board (6) installed in the second receiving groove (15) for receiving a second light signal formed by the second light beam after the action of the sample in the reaction cup (2).

2. The coagulation analyzer of claim 1, wherein, The wavelength of the first light beam emitted by the first emitting light source (3) is 405 nm, and the wavelength of the second light beam emitted by the second emitting light source (4) is 660 nm.

3. The coagulation analyzer of claim 2, wherein, The upper part of the first emitting light source (3) is sleeved in the first light source groove (12) through a first lamp sleeve (16), and the lower part of the first emitting light source (3) is installed in the first light source groove (12) through a first O-shaped ring (17).

4. The coagulation analyzer of claim 3, wherein, The emitting end of the first emitting light source (3) is provided with a light transmission hole, and the light transmission hole is installed with a 405 nm filter (18).

5. The coagulation analyzer of claim 1, wherein, The material of the test block body (1) is aluminum alloy 6061, and the surface thereof is subjected to black anodic oxidation treatment.

6. The coagulation analyzer according to any one of claims 2 to 5, characterized in that Further comprising: a third emitting light source (7) and a third circuit board (8); the top surface of the test block body (1) is further provided with a third reaction groove (19) for placing the reaction cup (2), and the side surface of the test block body (1) is further provided with a third light source groove (110) and a third receiving groove (111), wherein the third light source groove (110) and the third receiving groove (111) are both in communication with the third reaction groove (19); the third emitting light source (7) is installed in the third light source groove (110); the third circuit board (8) is installed in the third receiving groove (111) for receiving a third light signal formed by a third light beam emitted by the third emitting light source (7) after the action of the sample in the reaction cup (2); the wavelength of the third light beam emitted by the third emitting light source (7) is 660 nm.

7. The coagulation analyzer of claim 6, wherein, The photovoltaic cell of the first circuit board (5) is installed in the first receiving groove (14) for receiving the first light signal; the photovoltaic cell of the second circuit board (6) is installed in the second receiving groove (15) for receiving the second light signal; the photovoltaic cell of the third circuit board (8) is installed in the third receiving groove (111) for receiving the third light signal.

8. The coagulation analyzer of claim 6, wherein, The axis of the first light source groove (12) and the axis of the first receiving groove (14) are collinear; The axis of the second light source groove (13) and the axis of the second receiving groove (15) are collinear; The axis of the third light source groove (110) and the axis of the third receiving groove (111) are collinear.

9. The coagulation analyzer of claim 6, wherein, The test block body (1) is a polyhedron; The first light source groove (12), the second light source groove (13), the third light source groove (110), the first receiving groove (14), the second receiving groove (15) and the third receiving groove (111) are respectively arranged on different side faces of the test block body (1).

10. The coagulation analyzer of claim 6, wherein, Further comprising: A first tension spring (9) and a second tension spring (10); The top surface of the test block body (1) is further provided with a first placement groove (112), which is communicated with the top of the first reaction groove (11). The first tension spring (9) is installed in the first placement groove (112) and is used to elastically compress the side wall of one reaction cup (2) in the radial direction, so as to fix the reaction cup (2); The top surface of the test block body (1) is further provided with a second placement groove (113), which is communicated with the top of the third reaction groove (19). The second tension spring (10) is installed in the second placement groove (113) and is used to elastically compress the side wall of another reaction cup (2) in the radial direction, so as to fix the reaction cup (2).

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