Liquid sucking and injecting mechanism

Abstract

The utility model relates to the field of liquid-based cell pelleters, in particular to a liquid suction and injection mechanism, which is provided with at least two mounting positions and a mounting part, at least one mounting position is provided with a mounting groove, the mounting part is provided with a liquid suction and injection needle kit, the tail end of the liquid suction and injection needle kit is provided with a liquid suction and injection port, and the mounting part is arranged in the mounting groove and can be adjusted in the mounting groove. Adjustment comprises horizontal movement and angle adjustment, and the angle adjustment enables the liquid suction and injection openings of the liquid suction and injection needle suites on the multiple installation positions to be located on the same straight line. The structure of the mounting groove is adopted, the mounting piece arranged in the mounting groove can be freely adjusted in the mounting groove through the adjusting piece, the mounting angle of the liquid suction and injection mechanism can be conveniently adjusted, the liquid suction and injection openings of the liquid suction and injection pipe are located on the same straight line, and waste liquid can be conveniently and completely sucked; meanwhile, the position of each liquid suction and injection mechanism can be conveniently adjusted to be matched with the position of the disposable pipette tip, and the insertion success rate of the disposable pipette tip is increased.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of liquid-based cell smearing machine, concretely relates to a suction and injection mechanism. BACKGROUND

[0002] The existing multi-channel liquid-based cell smearing machine has 2-4 sets of suction and injection needle sets, and can simultaneously process 2-4 glass slides.

[0003] In order to smoothly insert and transfer the disposable pipette tip for the specimen, the suction and injection needle sets need to be arranged in parallel, so that the distance between them corresponds to the disposable pipette tip.

[0004] In order to prevent the liquid from directly impacting the cell layer on the glass slide when injecting the liquid, and to prevent the suction and injection port of the suction and injection needle set from touching the cell layer on the glass slide at the bottom of the liquid surface when sucking the liquid, the suction and injection port of the suction and injection needle set needs to be curved.

[0005] In order to completely suck the liquid, the method adopted is to use the suction and injection port to contact the inner wall of the container, and to tilt the container so that the lowest point of the liquid is on the intersection line of the container side wall and the ground. When sucking the liquid, each suction and injection needle set moves downward to suck the waste liquid, and continues to move downward as the liquid level decreases, until the suction and injection port moves to the lowest point of the liquid, thereby completely sucking the liquid to the maximum extent. Therefore, it is necessary to adjust each suction and injection port so that they are on the same straight line.

[0006] The existing technology has the following problems: 1. Due to the machining precision problem, the distance between the assembled suction and injection needle sets and the distance between the disposable pipette tips have deviations, and the suction and injection needle sets are fixedly installed on the suction and injection mechanism, so it is difficult to adjust the distance between the suction and injection needle sets, which leads to the fact that when the disposable pipette tip is inserted into the suction and injection mechanism, some suction and injection needle sets correspond to the disposable pipette tip, while the other suction and injection needle sets deviate from the position of the disposable pipette tip, resulting in the failure of the insertion of the disposable pipette tip; 2. Since the suction and injection needle sets are directly installed on the suction and injection mechanism, the position adjustment of the suction and injection ports of each suction and injection mechanism can only be made by bending the suction and injection pipe after installation, and the angle of the bending adjustment is limited, so the suction and injection ports cannot be on the same straight line, which leads to the fact that when sucking the liquid, some suction and injection ports cannot completely reach the lowest point of the liquid, resulting in the incomplete sucking of the liquid of some specimens.

[0007] Therefore, there is an urgent need for a suction and injection mechanism that is easy to install, to solve the problems of the failure of the insertion of the disposable pipette tip and the incomplete sucking of the waste liquid. SUMMARY

[0008] The utility model provides a kind of full-automatic liquid-based cell smearing machine, to solve the problem of the failure of the insertion of the disposable pipette tip and the incomplete sucking of the waste liquid in the related art.

[0009] In order to achieve the above object, the utility model provides a kind of suction and injection mechanism, with at least two installation sites, at least one installation site has installation groove, further including mounting piece, mounting piece is provided with suction and injection needle kit, suction and injection needle kit end has suction and injection port, mounting piece is placed in installation groove, and can be adjusted in installation groove, adjustment includes horizontal movement and angle adjustment, the angle adjustment makes the suction and injection port of suction and injection needle kit on multiple installation sites on the same straight line.

[0010] Further, a kind of suction and injection mechanism, with at least three installation sites, at least two installation sites have installation groove, further including mounting piece, mounting piece is provided with suction and injection needle kit, suction and injection needle kit end has suction and injection port, mounting piece is placed in installation groove, and can be adjusted in installation groove, adjustment includes horizontal movement and angle adjustment, the angle adjustment makes the suction and injection port of suction and injection needle kit on multiple installation sites on the same straight line.

[0011] Further, installation groove is the structure of recess on installation site, shape is matched with mounting piece, installation groove width is greater than mounting piece, the bottom of installation groove has baffle, the baffle is fixedly arranged on the bottom surface of installation site.

[0012] Further, the adjustment is realized by adjusting piece, adjusting piece includes oval through-hole arranged on installation groove and first threaded hole arranged on mounting piece, and the installation positions of the oval through-hole and the first threaded hole correspond.

[0013] Further, suction and injection port is curvedly arranged.

[0014] Further, adjusting piece further includes jackscrew, jackscrew is arranged on mounting piece, and jackscrew is in contact with suction and injection needle kit arranged on mounting piece.

[0015] Further, suction and injection needle kit includes positioning block, positioning hole is arranged on positioning block, mobile column is movably arranged in positioning hole, mobile column extends out of positioning hole at both ends, and the both ends are fixedly connected with mounting piece, at least one end of the both ends is provided with elastic element, and elastic element is in compression state.

[0016] Further, further include mobile column pressing plate, mobile column pressing plate has mounting hole on both sides, mounting piece has threaded hole, and threaded hole and mounting hole are matched.

[0017] Further, mounting piece has positioning slot, and the size of positioning slot is matched with positioning block, for limiting positioning block.

[0018] Further, second jackscrew is symmetrically arranged on the surface of mounting piece in contact with suction and injection needle kit, and the second jackscrew is ball head elastic jackscrew.

[0019] The utility model has the advantages that:

[0020] By adopting the structure of the installation groove, the installation piece placed in the installation groove can be adjusted arbitrarily in the installation groove through the adjusting piece, the installation angle of the liquid suction and injection mechanism is adjusted conveniently, the liquid suction and injection ports of the liquid suction and injection pipes are on a straight line, the waste liquid is conveniently sucked up, and meanwhile, the matching of the positions of the liquid suction and injection mechanisms and the position of the disposable pipette tip is conveniently adjusted, and the success rate of the insertion of the disposable pipette tip is improved. BRIEF DESCRIPTION OF DRAWINGS

[0021] In order to more clearly illustrate the technical schemes of the embodiments of the present application, the drawings needed to be used in the description of the embodiments of the present application will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor on the basis of the drawings.

[0022] Figure 1 It is a structural schematic diagram of the liquid suction and injection mechanism of the present application.

[0023] Figure 2 It is a partial enlarged view of the liquid suction and injection mechanism of the present application.

[0024] Figure 3 It is a structural schematic diagram of the installation position and installation groove of the present application.

[0025] Figure 4 It is a structural schematic diagram of the installation piece of the present application.

[0026] Figure 5 It is an exploded view of the liquid suction and injection mechanism of the present application.

[0027] Figure 6 It is a structural schematic diagram of the moving column pressing plate of the present application.

[0028] Figure 7 It is a back view of the liquid suction and injection mechanism of the present application.

[0029] Among them:

[0030] 1, liquid suction and injection mechanism; 2, installation position; 3, installation piece; 4, liquid suction and injection needle set; 5, liquid suction and injection port; 6, installation groove; 7, baffle; 8, oval through hole; 9, first threaded hole; 10, first jackscrew; 11, positioning block; 12, positioning hole; 13, moving column; 14, elastic piece; 15, moving column pressing plate; 16, installation hole; 17, positioning groove; 18 second jackscrew; 19, second threaded hole. DETAILED DESCRIPTION

[0031] With reference to the drawings of the embodiments of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described. Obviously, the described embodiments are some but not all of the embodiments of the present application. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative efforts fall within the scope of the present application.

[0032] In one aspect, as shown in Figures 1-5 and Figure 7 The present application provides a kind of suction and injection mechanism 1, with at least two installation sites 2, at least one installation site 2 has installation groove 6, further comprising mounting 3, mounting 3 is provided with suction and injection needle sleeve 4, suction and injection needle sleeve 4 end has suction and injection port 5, mounting 3 is placed in installation groove 6, and can be adjusted in installation groove 6, adjustment includes horizontal movement and angle adjustment, the angle adjustment makes the suction and injection port 5 of multiple installation sites 2 on suction and injection needle sleeve 4 on the same straight line.

[0033] It can be understood that suction and injection mechanism 1 is used to plug disposable pipette head and injection and suction, the horizontal distance between the suction and injection port 5 on each suction and injection needle sleeve 4 must be adapted to the horizontal distance of disposable pipette head, and the suction and injection port 5 on each suction and injection needle sleeve 4 must also be on a straight line, so that effective suction operation can be carried out at the same time.

[0034] The suction and injection mechanism 1 provided by the present embodiment can be directly installed on the installation site 2, or can be installed in the installation groove 6 through the mounting 3.

[0035] It can be understood that the suction and injection needle sleeve 4 installed on the installation site 2 does not perform position and angle adjustment. The suction and injection needle sleeve 4 installed in the installation groove 6 can be adjusted in position and angle through the horizontal movement and angle adjustment of the mounting 3 in the installation groove 6.

[0036] Specifically, the mounting 3 installed in the installation groove 6 can move horizontally in the installation groove 6, so as to adjust the distance between the suction and injection needle sleeve 4 on the mounting 3 and the adjacent suction and injection needle sleeve 4, so that the horizontal distance between the suction and injection ports 5 meets the requirement of plugging the disposable pipette head. The mounting 3 installed in the installation groove 6 can also be adjusted in angle in the installation groove 6, so as to adjust the angle of the suction and injection needle sleeve 4 on the mounting 3, so that the suction and injection port 5 on the suction and injection needle sleeve 4 is on a straight line with other suction and injection ports 5, meeting the suction and injection requirement. The horizontal movement and angle adjustment of the present embodiment are not limited by machining precision, and do not need to change the physical bending degree of the suction and injection needle sleeve 4, which is simple and flexible to operate.

[0037] Further, as shown in Figures 1-5 andFigure 7 As shown in the drawings, a kind of suction and injection mechanism 1, with at least three installation sites 2, at least two installation sites 3 have installation slot 6, further comprising mounting piece 3, mounting piece 3 is provided with suction and injection needle sleeve 4, suction and injection needle sleeve 4 end has suction and injection port 5, mounting piece 3 is placed in installation slot 6, and can be adjusted in installation slot 6, adjustment includes horizontal movement and angle adjustment, the angle adjustment makes the suction and injection port 5 of multiple installation sites 2 on suction and injection needle sleeve 4 be on the same straight line.

[0038] It can be understood that the suction and injection needle sleeve 4 installed in the installation site 2 does not carry out position and angle adjustment.And the suction and injection needle sleeve 4 installed in the installation slot 6 through the mounting piece 3 can be adjusted in position and angle by the horizontal movement and angle adjustment of the mounting piece 3 in the installation slot 6.

[0039] With the suction and injection needle sleeve 4 directly installed in the installation site 2 as reference, the horizontal position and angle of the two mounting pieces 3 installed in the installation slot 6 are adjusted to meet the requirements of the horizontal distance and the angle consistent with the suction and injection needle sleeve 4 directly installed in the installation site 2, that is, to make each suction and injection port 5 on the same straight line.

[0040] Further, as shown in the drawings, Figure 3 And Figure 7 The installation slot 6 is a recessed structure on the installation site 2, and the shape matches the mounting piece 3, the installation slot 6 is wider than the mounting piece 3, and the bottom of the installation slot 6 has a baffle 7, which is fixedly arranged on the bottom surface of the installation site 2.

[0041] It can be understood that the mounting piece 3 is movably placed in the installation slot 6, the installation slot 6 is a recessed structure on the installation site 2, and the shape matches the mounting piece 3, the installation slot 6 is wider than the mounting piece 3, that is, the installation slot 6 can provide a certain activity space for the mounting piece 3 to realize the adjustment function of the mounting piece 3, meet the requirements of the space arrangement of the suction and injection needle sleeve 4 on different mounting pieces 3, that is, by setting the installation slot 6 wider than the mounting piece 3, the horizontal movement of the mounting piece 3 in the installation slot 6 can be realized, and then the distance of different suction and injection needle sleeves 4 in the horizontal direction is adjusted; through the small-angle change of the mounting piece 3 in the installation slot 6 in the vertical direction, the angle adjustment of the suction and injection needle sleeve 4 can be realized, so that each suction and injection port 5 is on the same straight line. The bottom of the installation slot 6 has a baffle 7, which plays a blocking role for the mounting piece 3, so that the mounting piece 3 can be stably placed in the installation slot 6.

[0042] Further, as shown in the drawings, Figures 1-5 The adjustment is realized by adjusting piece, and the adjusting piece includes an oval through hole 8 arranged on the installation slot 6 and a first threaded hole 9 arranged on the mounting piece 3, and the installation positions of the oval through hole 8 and the first threaded hole 9 correspond.

[0043] Specifically, by horizontal displacement of the mounting member 3 in the mounting groove 6, the suction and injection needle sleeve 4 is displaced horizontally with the mounting member 3, so that the distance between the suction and injection needle sleeves 4 can be adjusted according to the distance between the disposable pipette tips, and the suction and injection needle sleeve 4 can be adapted to the distance of the disposable pipette tips, thereby reducing the failure rate of inserting the disposable pipette tips. When the suction and injection needle sleeve 4 is horizontally displaced, the first threaded hole 9 thereon is always within the range of the oval through hole 8, and when the suction and injection needle sleeve 4 is moved to a position meeting the horizontal distance requirement, a screw is screwed into the first threaded hole 9 of the mounting member 3 through the oval through hole 8, thereby fixing the suction and injection needle sleeve 4 in the mounting groove 6.

[0044] Further, as shown in Figure 1 and Figure 5 , the suction and injection port 5 is curvedly arranged.

[0045] Further, as shown in Figure 5 and Figure 7 , the adjusting member further comprises a first jackscrew 10, which is arranged on the mounting member 3 and in contact with the suction and injection needle sleeve 4 arranged on the mounting member 3.

[0046] Specifically, after the suction and injection needle sleeve 4 is arranged on the mounting member 3 and in contact with the first jackscrew 10, the height of the first jackscrew 10 can be adjusted to change the inclination angle of the suction and injection needle sleeve 4 in the vertical direction, thereby changing the position of the suction and injection port 5, and the height of different first jackscrews 10 can be adjusted to make the suction and injection ports 5 of different suction and injection needle sleeves 4 on the same straight line. When sucking, each suction and injection port 5 can touch the inner wall of the container at the same time, and the container can be inclined at the same angle, which is beneficial to sucking the waste liquid completely. It can be understood that if the suction and injection ports 5 are not on the same straight line, some containers will be inclined to the limit position, and some containers will not touch the suction and injection port 5, resulting in that the lowest point of the liquid surface is not on the intersection line of the bottom surface and the side surface, but on the entire bottom surface, and finally leading to incomplete sucking.

[0047] Further, as shown in Figure 1 and Figure 5 , the suction and injection needle sleeve 4 comprises a positioning block 11, the positioning block 11 is provided with a through positioning hole 12, a movable column 13 is movably arranged in the positioning hole 12, the movable column 13 extends out of the positioning hole 12 at both ends, and the two ends are fixedly connected with the mounting member 3, at least one end of the two ends is provided with an elastic member 14, and the elastic member 14 is in a compressed state.

[0048] The purpose of such arrangement is to enable the plurality of suction and injection needle sleeves 4 to adapt to the insertion of disposable pipette tips with different inner diameters.

[0049] Specifically, the positioning block 11 of the suction and injection needle set 4 is placed on the mounting member 3, the moving column 13 is fixed on the mounting member at both ends of the positioning hole 12, and the elastic member 14 is in a compressed state due to the resistance of the mounting member and the positioning block. After the suction and injection needle set 4 is subjected to pressure, relative displacement can be generated on the mounting member 3 due to the presence of the elastic member 14. After the external force disappears, the suction and injection needle set 4 returns to the original position under the action of the elastic member 14.

[0050] When the disposable pipette tip is inserted, the suction and injection mechanism 1 is driven by the mechanical arm to move downward. The disposable pipette tip with a small inner diameter or a high horizontal position is first inserted into the sleeve. The suction and injection mechanism 1 continues to move downward. The elastic member 14 of the suction and injection needle set 4 that first inserts the disposable pipette tip is compressed under the pressure of the disposable pipette tip, and the suction and injection needle set 4 and the sleeve above it are displaced upward. The other suction and injection needle sets 4 can continue to insert the disposable pipette tip by moving downward. After all the suction and injection needle sets 4 complete the insertion of the disposable pipette tip, the suction and injection mechanism 1 is driven by the mechanical arm to move upward and take away the disposable pipette tip.

[0051] If the elastic member 14 is not provided, the disposable pipette tip with a small inner diameter will generate a rigid pressure on the suction and injection mechanism 1 after being inserted, which will hinder the further downward movement of the suction and injection mechanism 1, and the disposable pipette tip with a large inner diameter will not be inserted.

[0052] Therefore, by providing the elastic member 14, the insertion failure of the disposable pipette tip with a large inner diameter can be avoided.

[0053] Further, as shown in Figure 5 and Figure 6 , it further comprises a moving column pressing plate 15, the moving column pressing plate 15 has mounting holes 16 on both sides, the mounting member 3 has second threaded holes 19, and the second threaded holes 19 are matched with the mounting holes 16.

[0054] The moving column pressing plate 15 is used to install the moving column 13 on the mounting member 3.

[0055] Specifically, the moving column 13 is placed between the second threaded holes 19, the moving column pressing plate 15 is placed on the moving column 13, and the mounting holes 16 of the moving column pressing plate 15 and the second threaded holes 19 are fixed by screws, thereby fixing the suction and injection needle set 4 on the mounting member 3.

[0056] Further, as shown in Figure 5 , the mounting member 3 has a positioning groove 17, the size of the positioning groove 17 is matched with the positioning block 11, and the positioning groove 17 is used to limit the positioning block 11.

[0057] It can be understood that by providing the positioning groove 17, the suction and injection needle set 4 can be conveniently and stably installed on the mounting member 3, and space is saved.

[0058] Further, as shown in Figure 5 and Figure 7 The second top pin 18 is symmetrically arranged on the surface of the mounting member 3 which contacts with the infusion needle cover set 4, and the second top pin 18 is a ball head elastic top pin.

[0059] After the positioning block 11 of the infusion needle cover set 4 is embedded into the positioning groove 17 of the mounting member 3, the two sides of the infusion needle cover set 4 contact the side surface of the mounting member 3 and contact the ball head elastic top pin of the side surface of the mounting member 3. When the infusion needle cover set 4 moves up and down, the two sides of the infusion needle cover set 4 do not directly rub against the side surface of the mounting member 3, but slide on the ball head of the ball head elastic top pin, which reduces the friction and makes the movement of the infusion needle cover set 4 more smooth.

[0060] On the other hand, a method for adjusting the infusion needle cover set 4 is also provided, which comprises the following steps:

[0061] S1, horizontal movement, the horizontal movement of the infusion needle cover set 4 is realized by adjusting the horizontal position of the mounting member 3 in the mounting groove 6;

[0062] S2, angle adjustment, the angle adjustment of the infusion needle cover set 4 is realized by adjusting the height of the top pin.

[0063] It should be noted that in this document, the terms "comprising", "including", or any other variant thereof are intended to cover non-exclusive inclusions, so that processes, methods, articles or devices including a series of elements not only include those elements, but also include other elements not explicitly listed, or include elements inherent to such processes, methods, articles or devices. Without more limitations, the element defined by the statement "including a" does not exclude the presence of another identical element in the process, method, article or device including the element.

[0064] The embodiments of the present application are described above in combination with the drawings, but the present application is not limited to the above specific embodiments, and the above specific embodiments are only illustrative, not restrictive. Those skilled in the art can make many forms under the inspiration of the present application without departing from the purpose of the present application and the scope protected by the claims, and all of them belong to the protection of the present application.

Claims

1. A kind of suction and injection mechanism, with at least two installation sites, it is characterized in being, At least one installation site has installation slot; Further comprising mounting piece, mounting piece is provided with suction and injection needle kit, and suction and injection needle kit end has suction and injection port; Mounting piece is placed in installation slot, and can be adjusted in installation slot, adjustment includes horizontal movement and angle adjustment, the angle adjustment makes the suction and injection port of suction and injection needle kit on multiple installation sites be on the same straight line.

2. A kind of suction and injection mechanism, with at least three installation sites, it is characterized in being, At least two installation sites have installation slot; Further comprising mounting piece, mounting piece is provided with suction and injection needle kit, and suction and injection needle kit end has suction and injection port; Mounting piece is placed in installation slot, and can be adjusted in installation slot, adjustment includes horizontal movement and angle adjustment, the angle adjustment makes the suction and injection port of suction and injection needle kit on multiple installation sites be on the same straight line.

3. The liquid absorbing and injecting mechanism according to any one of claims 1-2, wherein Installation slot is the recessed structure on installation site, shape is matched with mounting piece, installation slot width is greater than mounting piece, and the bottom of installation slot has baffle, the baffle is fixedly arranged on the bottom surface of installation site.

4. The liquid absorbing and injecting mechanism according to any one of claims 1 to 2, characterized by The adjustment is realized by adjusting piece, adjusting piece includes the elliptical through-hole arranged on installation slot and the first threaded hole arranged on mounting piece, and the installation position of the elliptical through-hole and the first threaded hole corresponds.

5. The liquid absorbing and injecting mechanism according to any one of claims 1 to 2, wherein Suction and injection port is curvedly arranged.

6. The liquid intake mechanism of claim 5, wherein Adjusting piece further includes first top pin, and first top pin is arranged on mounting piece, and first top pin is in contact with suction and injection needle kit arranged on mounting piece.

7. The liquid intake mechanism of claim 6, wherein Suction and injection needle kit includes positioning block, and positioning hole is arranged in positioning block, and mobile column is movably arranged in positioning hole, and mobile column two ends extend out of positioning hole, and the two ends are fixedly connected with mounting piece, and at least one end of the two ends is provided with elastic element, and elastic element is in compression state.

8. The liquid intake mechanism of claim 7, wherein, Further comprising mobile column pressing plate, and mobile column pressing plate two sides have mounting hole, and mounting piece has second threaded hole, and second threaded hole is matched with mounting hole.

9. The liquid intake mechanism of claim 8, wherein, Mounting piece has positioning slot, and the size of positioning slot is matched with positioning block, for limiting positioning block.

10. The liquid absorbing and injecting mechanism according to claim 9, wherein The surface of mounting piece in contact with suction and injection needle kit is symmetrically provided with second top pin, and the second top pin is ball head elastic top pin.

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