Collagen raw material cobalt 60 irradiation sterilization box
By designing a cobalt-60 irradiation sterilization chamber for collagen raw materials, and utilizing the lining and freezing chamber structure, the problem of instability of collagen raw materials under low temperature conditions was solved, achieving stability and cost-effectiveness in low-temperature irradiation sterilization.
Patent Information
- Application Number
- CN202520247275.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-17
- Publication Date
- 2026-02-13
- Estimated Expiration
- 2035-02-17
AI Technical Summary
In existing technologies, collagen raw materials are unstable when placed at low temperatures, leading to unstable product quality during irradiation sterilization. Furthermore, high-temperature sterilization can damage the collagen structure, and existing methods suffer from high costs or difficulties in reconstitution.
A cobalt-60 irradiation sterilization box for collagen raw materials was designed, comprising an internal hollow insulated box and an inner box. The inner box consists of upper and lower linings with grooves for placing collagen raw material bottles. The external freezing chamber is used to place dry ice to ensure a low temperature. The inner box is fixed by slots and anti-slip posts to prevent shaking.
It effectively maintains the low temperature of collagen raw materials during transportation and irradiation, reduces vibration, ensures the stability of irradiation dose, avoids collagen deterioration, and reduces production costs.
Smart Images

Figure CN223900195U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model belongs to collagen storage device technical field, more specifically, relate to a collagen raw material cobalt 60 irradiation sterilization box. BACKGROUND
[0002] Sterilization by irradiation can directly irradiate packaging raw materials, semi-finished products and finished products at room temperature through electron beams without unpacking, effectively and comprehensively kill different types of microorganisms by flexibly adjusting the sterilization dose, and is convenient, fast, comprehensive and thorough. This technology is also called physical cold processing disinfection and sterilization, has little adverse reaction on products, is especially suitable for edible products that cannot use high temperature and high pressure or chemical sterilization, and provides strong technical support for food, cosmetics and daily necessities industries that need external disinfection and sterilization. The device is a collagen raw material irradiation sterilization box.
[0003] Collagen is the most important component of extracellular matrix and has unique physiological activity. It can participate in cell migration, differentiation and proliferation, give bone tendons, cartilage and skin certain mechanical strength, and has wide application in medical and health fields such as burns, wounds, corneal diseases, beauty, hard tissue repair and wound hemostasis due to its weak antigenicity and good biocompatibility. The triple helix structure of collagen protein is not resistant to high temperature, and high temperature will cause irreversible damage to the structure of collagen protein. Conventional high-temperature sterilization technology cannot meet the sterilization needs of collagen protein. There are two main processes for preparing sterile collagen at present. One is to add irradiation protectant in the collagen solution (CN115611978B), and the other is to freeze-dry collagen protein into powder at low temperature and then perform low-temperature irradiation sterilization (CN118141975A). The former adds irradiation protectant in collagen, which will have certain impact on the subsequent application of collagen. Removing the irradiation protectant will increase the production process and cost. The latter can not add irradiation protectant, but the subsequent collagen resolubilization is difficult, and there is a certain risk of contamination during the resolubilization process. Since high temperature will cause irreversible damage to collagen, the better choice at present is to directly sterilize the collagen solution at low temperature. How to cold-transport and sterilize at low temperature is undoubtedly a headache for enterprises.
[0004] The collagen raw material cobalt 60 irradiation sterilization box is used for placing collagen raw material products, so that the cobalt 60 irradiation treatment can be stably carried out. However, when the collagen raw material is placed, the products are placed in disorder, the low-temperature state cannot be effectively maintained, and the low-temperature irradiation operation of the collagen raw material products in the later stage is not conducive. UTILITY MODEL CONTENTS
[0005] The main purpose of the utility model is to provide a collagen raw material cobalt 60 irradiation sterilization box to solve the problems in the background art.
[0006] According to the first aspect of the utility model, a kind of collagen raw material Co-60 irradiation sterilization box is provided, including the heat preservation box of inside hollow, the inside of the heat preservation box is fixedly provided with inner box, the middle part of the inner box is hollowly arranged, freezing cavity for placing dry ice is equipped between the outer wall of the inner box and the inner wall of the heat preservation box, the inner box includes upper lining and lower lining, the upper lining is arranged above the lower lining, the bottom of the lower lining is equipped with clamping groove, the inside bottom end of the heat preservation box is equipped with anti-skid column matched with the clamping groove.
[0007] In a specific embodiment of the utility model, the middle part of the upper lining and the lower lining is provided with two recesses for storing bottles filled with collagen raw materials.
[0008] In a specific embodiment of the utility model, the sum of the depths of the upper and lower recesses is equal to the width of the bottles filled with collagen raw materials.
[0009] In a specific embodiment of the utility model, the recesses are symmetrically arranged on the upper lining and the lower lining, respectively.
[0010] In a specific embodiment of the utility model, the bottom of the lower lining is provided with a plurality of through holes, and the through holes are respectively connected with the freezing cavity and the recesses.
[0011] In a specific embodiment of the utility model, the freezing cavity is arranged on the outer periphery of the inner box.
[0012] In a specific embodiment of the utility model, the upper lining and the lower lining are rectangular structures.
[0013] In a specific embodiment of the utility model, the top of the heat preservation box is provided with a heat preservation cover.
[0014] The above technical solution of the utility model has at least one of the following advantages or beneficial effects:
[0015] The upper and lower linings and the hollow area therein are arranged to facilitate the storage and placement of collagen raw materials. The clamping groove is inserted into the anti-skid column to reduce the vibration of collagen raw materials in the inner box during transportation due to collision. The freezing cavity is arranged to ensure that the collagen raw materials do not deteriorate during transportation and irradiation. BRIEF DESCRIPTION OF DRAWINGS
[0016] The utility model will be further described below in combination with the drawings and examples;
[0017] Figure 1 is a sectional view of the collagen raw material Co-60 irradiation sterilization box in an embodiment of the utility model;
[0018] Figure 2is a top view of the lower inner liner in an embodiment of the present utility model;
[0019] Figure 3 is a side view of the lower inner liner in an embodiment of the present utility model;
[0020] Figure 4 is a bottom view of the lower inner liner in an embodiment of the present utility model;
[0021] Figure 5 is a top view of the upper inner liner in an embodiment of the present utility model;
[0022] Figure 6 is a side view of the upper inner liner in an embodiment of the present utility model. DETAILED DESCRIPTION
[0023] The embodiments of the present utility model will be described in detail below, and examples of the embodiments are shown in the drawings, wherein the same or similar reference numerals represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are only used to explain the present utility model, and cannot be understood as a limitation on the present utility model.
[0024] In the description of the present utility model, it should be understood that the orientation description, such as the orientation or position relationship indicated by up, down, front, back, left, right, etc. is based on the orientation or position relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, and does not indicate or imply that the device or element indicated must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model.
[0025] In the description of the present utility model, the meaning of several is one or more, and the meaning of multiple is more than two, greater than, less than, more than, etc. are understood as not including the number, and above, below, etc. are understood as including the number. If it is described as first, second, it is only used for the purpose of distinguishing technical features, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features or implicitly indicating the sequence of indicated technical features.
[0026] In addition, the terms "first" and "second" are only used for the purpose of description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. Therefore, the features limited by "first" and "second" can explicitly or implicitly include one or more features.
[0027] In the description of the utility model, it is necessary to explain that, unless there is definite stipulation and limitation, the term "connection" should be understood broadly, for example, it can be fixed connection or movable connection, can be detachable connection or non detachable connection, or integrally connected, can be mechanical connection, can be electrical connection or can communicate with each other, can be directly connected, can be indirectly connected through intermediate medium, can be internal communication of two elements, indirect communication or interaction of two elements.
[0028] The following disclosure provides many different implementations or examples to implement different schemes of the utility model.
[0029] Referring to Figures 1 to 6 As shown in the figure, a collagen raw material Co-60 irradiation sterilization box is provided, which comprises an internal hollow heat preservation box 1, an inner box is fixedly arranged in the heat preservation box 1, the middle part of the inner box is hollowly arranged, a refrigeration cavity 4 for placing dry ice is arranged between the outer wall of the inner box and the inner wall of the heat preservation box 1, the inner box comprises an upper inner lining 2 and a lower inner lining 3, the upper inner lining 2 is arranged above the lower inner lining 3, the bottom of the lower inner lining 3 is provided with a clamping groove 6, and the inner bottom end of the heat preservation box 1 is provided with an anti-skid column 7 matched with the clamping groove 6.
[0030] In the embodiment, the inner box is fixedly arranged in the heat preservation box 1, the inner box comprises the upper inner lining 2 and the lower inner lining 3, the bottom corners of the lower inner lining 3 are provided with the clamping grooves 6, and the inner bottom corners of the heat preservation box 1 are also provided with the anti-skid columns 7 correspondingly, the clamping grooves 6 can be clamped into the anti-skid columns 7, so that the lower inner lining 3 is fixed, and the inner box can be prevented from shaking, preferably, the lower inner lining 3 can also be detached from the inner part of the heat preservation box 1, so as to facilitate the operation of the staff, the lower inner lining 3 and the upper inner lining 2 can be hingedly connected or buckled, so as to facilitate the staff to open and place the collagen raw material, the refrigeration cavity 4 is arranged between the outer walls of the upper inner lining 2 and the lower inner lining 3 and the inner wall of the heat preservation box 1, and a plurality of dry ice can be placed in the refrigeration cavity 4, so that the temperature in the heat preservation box 1 is reduced, and the collagen raw material is better stored.
[0031] In an embodiment of the utility model, the middle parts of the upper inner lining 2 and the lower inner lining 3 are provided with two recesses 5 for storing bottles filled with collagen raw material, further, the sum of the depths of the two recesses 5 above and below is equal to the width of the bottle filled with collagen raw material, the two recesses 5 on the upper inner lining 2 are arranged in correspondence with the two recesses 5 of the lower inner lining 3, the sum of the depths of the corresponding two recesses 5 above and below is equal to the width of the bottle filled with collagen raw material, the bottle filled with collagen raw material in the recess 5 cannot move, the stability of different batches of irradiation doses is maintained, preferably, the width of the recess 5 is equal to the width of the bottle, or a limiting sponge is arranged in the recess 5, so as to avoid the movement of the bottle during transportation.
[0032] In one embodiment of the utility model, the recesses 5 are symmetrically arranged on the upper inner liner 2 and the lower inner liner 3 respectively, the number of the recesses 5 on the upper inner liner 2 and the lower inner liner 3 is two respectively, and then two storage bottles filled with collagen raw materials can be stored at most.
[0033] In one embodiment of the utility model, the bottom of the lower inner liner 3 is provided with a plurality of through holes 8, the plurality of through holes 8 are respectively communicated with the refrigeration cavity 4 and the recess 5, a plurality of dry ice is placed in the refrigeration cavity 4, the temperature in the refrigeration cavity 4 is reduced, the cold air is transmitted into the recess 5 through the through holes 8, the temperature in the recess 5 is reduced, and the outer sides of the two inner liners are also reduced at the same time, so that the collagen raw materials can be kept in the frozen state and are not easy to be polluted.
[0034] Preferably, the side of the upper inner liner 2 away from the recess 5 is also provided with a hole, the hole is communicated with the recess 5 and the refrigeration cavity 4 of the upper inner liner 2, the cold air can be transmitted faster, and the collagen raw materials can be kept better.
[0035] In one embodiment of the utility model, the refrigeration cavity 4 is arranged on the outer periphery of the inner box, and is arranged around the outer periphery of the inner box, so that the dry ice can be evenly placed, the outer side of the inner box can be quickly cooled, and the temperature in the recess 5 is reduced.
[0036] In one embodiment of the utility model, the upper inner liner 2 and the lower inner liner 3 are in rectangular structure.
[0037] In one embodiment of the utility model, the top of the heat preservation box 1 is provided with a heat preservation cover 9, the heat preservation cover 9 and the heat preservation box 1 can be connected through a hinge or a buckle, and the purpose is to keep the temperature in the heat preservation box 1, preferably, after the heat preservation cover 9 is closed, the side of the heat preservation cover 9 close to the upper inner liner 2 is attached to the upper inner liner 2, so that the position of the inner box can be reinforced and is not easy to shake during transportation.
[0038] Working principle:
[0039] When using, firstly, the lower inner liner 3 is placed in the inside of the heat preservation box 1, the clamping groove 6 at the bottom of the lower inner liner 3 is clamped with the anti-skid column 7 in the inside of the heat preservation box 1, the lower inner liner 3 is prevented from shaking in the inside of the heat preservation box 1, several dry ice is placed in the freezing cavity 4 between the lower inner liner 3 and the heat preservation box 1 to reduce the temperature in the heat preservation box 1, then the product collagen raw material in the bottle after being pre-frozen is placed in the recess 5 in the lower inner liner 3, the size of the recess 5 is designed according to the size of the bottle body containing the collagen raw material, the depth of the recess 5 is half of the width of the bottle body, so that the bottle body filled with the collagen raw material in the recess 5 cannot move, the stability of the irradiation dose of different batches is kept, after the recess 5 is filled with the collagen raw material, the upper inner liner 2 is covered on the lower inner liner 3, the other half of the bottle body of the collagen raw material exposed is clamped with the recess 5 in the upper inner liner 2, the upper inner liner 2 and the lower inner liner 3 are kept together to play a fixing role, then the dry ice is filled in the freezing cavity 4, the heat preservation cover 9 is covered, the dry ice in the freezing cavity 4 can keep the collagen raw material in the recess 5 in the upper inner liner 2 and the lower inner liner 3 in a frozen state through the through hole 8.
[0040] Although the embodiments of the present application have been shown and described, those skilled in the art can understand that various changes, modifications, replacements and variations can be made to the embodiments without departing from the principles and purposes of the present application, the scope of the present application is defined by the claims and their equivalents.
Claims
1. A collagen raw material Co-60 irradiation sterilization box comprising a heat preservation box (1) with an internal hollow, characterized in that, The inner part of the heat preservation box (1) is fixedly provided with an inner box, the middle part of the inner box is provided with a hollow structure, a freezing cavity (4) for placing dry ice is arranged between the outer wall of the inner box and the inner wall of the heat preservation box (1), the inner box comprises an upper inner liner (2) and a lower inner liner (3), the upper inner liner (2) is arranged above the lower inner liner (3), the bottom of the lower inner liner (3) is provided with a clamping groove (6), and the inner bottom end of the heat preservation box (1) is provided with an anti-skid column (7) matched with the clamping groove (6).
2. Collagen raw material Co-60 irradiation sterilization box according to claim 1, characterized in that, The middle part of the upper inner liner (2) and the lower inner liner (3) is provided with two recesses (5) for storing bottles filled with collagen raw materials.
3. The collagen raw material Co-60 irradiation sterilization box according to claim 2, characterized in that, The sum of the depths of the two recesses (5) is equal to the width of the bottle filled with collagen raw materials.
4. The collagen raw material Co-60 irradiation sterilization box according to claim 2, characterized in that, The recesses (5) are symmetrically arranged on the upper inner liner (2) and the lower inner liner (3) respectively.
5. The collagen raw material Co-60 irradiation sterilization box according to claim 2, characterized in that, The bottom of the lower inner liner (3) is provided with a plurality of through holes (8), and the plurality of through holes (8) are respectively communicated with the freezing cavity (4) and the recess (5).
6. The collagen raw material Co-60 irradiation sterilization box according to claim 1, characterized in that, The freezing cavity (4) is arranged on the outer periphery of the inner box.
7. The collagen raw material Co-60 irradiation sterilization box according to claim 1, characterized in that, The upper inner liner (2) and the lower inner liner (3) are rectangular structures.
8. The collagen raw material Co-60 irradiation sterilization box according to claim 1, characterized in that, The top of the heat preservation box (1) is provided with a heat preservation cover (9).
Citation Information
Patent Citations
Use of an irradiant in the preparation of collagen products
CN115611978B
Preparation method and application of collagen freeze-dried powder
CN118141975A