Decellularization device for tendon repair material

By using a decellularization device for tendon repair materials, a rotating block drives an interactive container to rotate rapidly, solving the problems of cell damage and excessive time consumption in existing technologies and achieving a highly efficient decellularization process.

CN223906828UActive Publication Date: 2026-02-13BEIJING KEJIAN BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202520053987.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-10
Publication Date
2026-02-13
Estimated Expiration
2035-01-10

AI Technical Summary

Technical Problem

Existing technologies for preparing decellularized tendon materials suffer from low decellularization efficiency due to internal stirring damaging cells and excessively long shaking time.

Method used

A decellularization device for tendon repair materials is used. A moving limiting plate squeezes and confines the interactive container to a rotating block. The rotating block drives the interactive container to rotate rapidly, allowing the tendon to come into full contact with the decellularization solution.

Benefits of technology

It improves the efficiency of decellularization, enables rapid contact between the tendon and the decellularization solution, reduces cell damage, and shortens the preparation time.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a tendon repair material decellularization device which comprises a fixed top plate, the lower surface of the fixed top plate is fixedly connected with a supporting rod, the lower surface of the supporting rod is fixedly connected with a bottom plate, the upper surface of the bottom plate is fixedly connected with a protection box body, a rotating round block is arranged in the protection box body, and the rotating round block is fixedly connected with the bottom plate. A circular block groove is formed in the upper surface of the rotating circular block, an interaction container is arranged on the surface of the circular block groove, a limiting circular plate is arranged over the rotating circular block, and an electric push rod is fixedly connected to the lower surface of the fixed top plate. Through the structure, the limiting circular plate, the rotating circular block and the interaction container are arranged, the limiting circular plate can be moved to extrude and limit the interaction container on the rotating circular block, and the rotating circular block is rotated to drive the interaction container to quickly rotate, so that tendon decellularization in the interaction container is in full contact with a decellularization solution, and the decellularization efficiency is effectively improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the field of biological material science and technology, and concretely relates to a tendon repair material decellularization device. BACKGROUND

[0002] The decellularized tendon material is a biological material that retains the mechanical structure unit and cell adhesion structure inherent to tendon / ligament ECM, but removes the cell components. The material has good mechanical properties and biocompatibility, and can be directly applied to ligament and tendon repair and reconstruction.

[0003] When decellularization is prepared, the decellularization solution is generally added to contact the tendon cells, and internal stirring or shaking is used to make the two contact each other, to drive the tendon cells to remove the cell components. Internal stirring will cause damage to the tendon cells, and separate shaking is time-consuming and not conducive to preparation, reducing the efficiency of decellularization. UTILITY MODEL CONTENT

[0004] The utility model discloses a tendon repair material decellularization device, which can move the limiting circular plate to extrude and restrict the interactive container on the rotating circular block, rotate the rotating circular block to drive the interactive container to rotate quickly, make the tendon in the interactive container fully contact with the decellularization solution, and effectively improve the efficiency of decellularization.

[0005] To achieve the above-mentioned purpose, a tendon repair material decellularization device is provided, which comprises a fixed top plate, a support rod is fixedly connected to the lower surface of the fixed top plate, a bottom plate is fixedly connected to the lower surface of the support rod, a protection box body is fixedly connected to the upper surface of the bottom plate, a rotating circular block is arranged in the protection box body, a circular block groove is arranged on the upper surface of the rotating circular block, an interactive container is arranged on the surface of the circular block groove, and a limiting circular plate is arranged directly above the rotating circular block. The protection box body is arranged to facilitate the protection of the internal structure, the rotating circular block is arranged to facilitate the driving rotation of the interactive container, and the circular block groove is arranged to facilitate the restriction of the interactive container on the rotating circular block.

[0006] According to the tendon repair material decellularization device, the lower surface of the fixed top plate is fixedly connected with an electric push rod, the moving end of the electric push rod is fixedly connected with a bearing, the surface of the limiting circular plate is provided with a through groove, and the surface of the through groove of the limiting circular plate is fixedly connected with the bearing. The electric push rod is arranged to facilitate the movement of the bearing and drive the movement of the limiting circular plate, and the bearing is arranged to facilitate the fixation of the limiting circular plate on the electric push rod and the rotation of the interactive container.

[0007] According to the tendon repair material decellularization device, the cylindrical surface of the rotating circular block is fixedly connected with a connecting circular ring, a box groove is formed in the inner side of the protection box body close to the upper surface, and the groove surface of the protection box body is rotationally connected with the connecting circular ring.

[0008] According to the tendon repair material decellularization device, the inner side of the protection box body is fixedly connected with a motor, the output end of the motor is fixedly connected with a connecting cylinder, and the cylindrical surface of the connecting cylinder is fixedly connected with the rotating circular block.

[0009] According to the tendon repair material decellularization device, the surface of the protection box body is fixedly connected with an air outlet circular pipe, the inside of the air outlet circular pipe is communicated with the inside of the protection box body, and the upper surface of the bottom plate is fixedly connected with an air pump.

[0010] According to the tendon repair material decellularization device, the surface of the protection box body is fixedly connected with an air inlet circular pipe, the inside of the air inlet circular pipe is communicated with the inside of the protection box body, and the inside of the air pump is communicated with the inside of the air inlet circular pipe.

[0011] According to the tendon repair material decellularization device, the number of the supporting rods is two, and the positions of the two supporting rods are located on the same vertical plane.

[0012] According to the tendon repair material decellularization device, the lower surface of the limiting circular plate is provided with a rubber circular pad, and the material of the interactive container is polypropylene.

[0013] The beneficial effects of the tendon repair material decellularization device are as follows: the limiting circular plate, the rotating circular block and the interactive container are arranged, the interactive container is pressed and limited on the rotating circular block by moving the limiting circular plate, the interactive container is rapidly rotated by rotating the rotating circular block, the tendon decellularization in the interactive container is fully contacted with the decellularization solution, and the decellularization efficiency is effectively improved.

[0014] The additional aspects and advantages of the present application will be partially given in the following description, partially will become obvious from the following description, or will be understood by the practice of the present application. BRIEF DESCRIPTION OF DRAWINGS

[0015] The utility model is further illustrated below in combination with the drawings and embodiments.

[0016] Fig. 1 It is a whole structure schematic view of the utility model of a tendon repair material acellular device.

[0017] Fig. 2 It is a lower structure schematic view of the utility model of a tendon repair material acellular device.

[0018] Fig. 3 It is a protection box internal structure schematic view of the utility model of a tendon repair material acellular device.

[0019] Fig. 4 It is a limit round plate upper structure schematic view of the utility model of a tendon repair material acellular device.

[0020] Legend:

[0021] 1, fixed top plate, 2, support rod, 3, interactive container, 4, protection box, 5, bottom plate, 6, outlet round pipe, 7, rotating round block, 8, connecting round ring, 9, box recess, 10, motor, 11, inlet round pipe, 12, air pump, 13, round block recess, 14, connecting cylinder, 15, limit round plate, 16, electric push rod, 17, bearing. Specific embodiments

[0022] This part will describe the specific embodiments of the utility model in detail, and the preferred embodiments of the utility model are shown in the drawings, and the drawings are used to supplement the description of the text part, so that people can intuitively and visually understand each technical feature and the overall technical scheme of the utility model, but it cannot be understood as the limitation of the protection scope of the utility model.

[0023] Referring to Figs. 1 to 4 , the utility model embodiment a tendon repair material acellular device, it includes fixed top plate 1, the lower surface fixed connection of fixed top plate 1 has support rod 2, the lower surface fixed connection of support rod 2 has bottom plate 5, the upper surface fixed connection of bottom plate 5 has protection box 4, the inside of protection box 4 is provided with rotating round block 7, the upper surface of rotating round block 7 is provided with round block recess 13, the surface of round block recess 13 is provided with interactive container 3, when using, put tendon material and acellular solvent into the inside of interactive container 3, the just above rotating round block 7 is provided with limit round plate 15.

[0024] The lower surface of the fixed top plate 1 is fixedly connected with an electric push rod 16, the moving end of the electric push rod 16 is fixedly connected with a bearing 17, the electric push rod 16 is started to push the bearing 17 to move up and down, the surface of the limiting circular plate 15 is provided with a through groove, the surface of the through groove of the limiting circular plate 15 is fixedly connected with the bearing 17, and the limiting circular plate 15 moves up and down along with the bearing 17.

[0025] The cylindrical surface of the rotating circular block 7 is fixedly connected with a connecting circular ring 8, the inner side of the protection box body 4 close to the upper surface is provided with a box body groove 9, the groove surface of the protection box body 4 is rotationally connected with the connecting circular ring 8, and the rotating circular block 7 rotates on the surface of the box body groove 9 under the limitation of the connecting circular ring 8.

[0026] The inner lower surface of the protection box body 4 is fixedly connected with a motor 10, the output end of the motor 10 is fixedly connected with a connecting cylinder 14, the cylindrical surface of the connecting cylinder 14 is fixedly connected with the rotating circular block 7, the motor 10 drives the connecting cylinder 14 to rotate, and drives the rotating circular block 7 to rotate.

[0027] The surface of the protection box body 4 is fixedly connected with an air outlet circular pipe 6, the hot gas flow in the protection box body 4 is led out to the outside through the air outlet circular pipe 6, the inside of the air outlet circular pipe 6 is communicated with the inside of the protection box body 4, and the upper surface of the bottom plate 5 is fixedly connected with an air pump 12.

[0028] The surface of the protection box body 4 is fixedly connected with an air inlet circular pipe 11, the inside of the air inlet circular pipe 11 is communicated with the inside of the protection box body 4, the inside of the air pump 12 is communicated with the inside of the air inlet circular pipe 11, and the air pump 12 provides cooling gas for the inside of the protection box body 4 through the air inlet circular pipe 11 to cool the motor 10.

[0029] The number of the supporting rods 2 is two, the positions of the two supporting rods 2 are located on the same vertical plane, the two supporting rods 2 support the two sides of the device respectively, the lower surface of the limiting circular plate 15 is provided with a rubber circular pad, the material of the interactive container 3 is polypropylene, and the rubber circular pad of the limiting circular plate 15 extrudes the upper part of the interactive container 3.

[0030] Working principle: before starting the device, the prepared tendon material and the decellularization solvent are placed in the interactive container 3, the interactive container 3 is placed on the round block groove 13, the electric push rod 16 is started to push the limiting round plate 15 to limit the interactive container 3 on the rotating round block 7, the motor 10 is started to drive the connecting cylinder 14 to rotate to drive the rotating round block 7 and the connecting ring 8 to rotate, the connecting ring 8 rotates on the surface of the box groove 9, the interactive container 3 rotates, the internal tendon material and the decellularization solvent of the interactive container 3 are in close contact, the limiting round plate 15 rotates under the limitation of the bearing 17, after reaching the set time, the motor 10 is stopped, the electric push rod 16 is pulled to remove the limitation of the interactive container 3, the interactive container 3 is removed, the separated tendon is treated, and the efficiency of the decellularization is improved.

[0031] The embodiments of the utility model are described in detail above in combination with the drawings, but the utility model is not limited to the above-mentioned embodiments, and various changes can be made within the knowledge range of ordinary skilled in the art without departing from the purpose of the utility model.

Claims

1. A decellularization device for tendon repair material comprising a fixed top plate (1), characterized in that, The lower surface of the fixed top plate (1) is fixedly connected with a supporting rod (2), the lower surface of the supporting rod (2) is fixedly connected with a bottom plate (5), the upper surface of the bottom plate (5) is fixedly connected with a protection box (4), the inside of the protection box (4) is provided with a rotating circular block (7), the upper surface of the rotating circular block (7) is provided with a circular block groove (13), the surface of the circular block groove (13) is provided with an interactive container (3), and the top of the rotating circular block (7) is provided with a limiting circular plate (15).

2. The acellular tendon repair material device of claim 1, wherein, The lower surface of the fixed top plate (1) is fixedly connected with an electric push rod (16), the moving end of the electric push rod (16) is fixedly connected with a bearing (17), the surface of the limiting circular plate (15) is provided with a through groove, and the through groove surface of the limiting circular plate (15) is fixedly connected with the bearing (17).

3. The acellular tendon repair material device of claim 1, wherein, The cylindrical surface of the rotating circular block (7) is fixedly connected with a connecting circular ring (8), the inside of the protection box (4) is provided with a box groove (9) close to the upper surface, and the groove surface of the protection box (4) is rotatably connected with the connecting circular ring (8).

4. The acellular tendon repair material device of claim 1, wherein, The inside lower surface of the protection box (4) is fixedly connected with a motor (10), the output end of the motor (10) is fixedly connected with a connecting cylinder (14), and the cylindrical surface of the connecting cylinder (14) is fixedly connected with the rotating circular block (7).

5. The acellular tendon repair material device of claim 1, wherein, The surface of the protection box (4) is fixedly connected with an air outlet circular pipe (6), the inside of the air outlet circular pipe (6) is communicated with the inside of the protection box (4), and the upper surface of the bottom plate (5) is fixedly connected with an air pump (12).

6. The acellular tendon repair material device of claim 5, wherein, The surface of the protection box (4) is fixedly connected with an air inlet circular pipe (11), the inside of the air inlet circular pipe (11) is communicated with the inside of the protection box (4), and the inside of the air pump (12) is communicated with the inside of the air inlet circular pipe (11).

7. The acellular tendon repair material device of claim 1, wherein, The number of the supporting rod (2) is two, and the positions of the two supporting rods (2) are located on the same vertical plane.

8. The acellular tendon repair material device of claim 1, wherein, The lower surface of the limiting circular plate (15) is provided with a rubber circular pad, and the material of the interactive container (3) is polypropylene.