Sperm optimization device

Abstract

The utility model relates to the technical field of assisted reproduction medical instruments, in particular to a sperm optimization device, which comprises a screening tank, a sperm extraction tank, a sperm extraction tank, a sperm extraction tank, a sperm extraction tank, a sperm extraction tank, a sperm extraction tank and a sperm extraction tank, the L-shaped channel is arranged in the screening groove and is composed of a first channel section and a second channel section, the inlet end of the L-shaped channel is located in the storage groove, the outlet end of the L-shaped channel is located in the optimization groove, and a micro-filtration membrane is arranged on the L-shaped channel; the centrifugal impeller is installed in the optimization groove, and the centrifugal impeller can enable local water flow in the optimization groove to circularly flow in the direction from the outlet end of the second channel section to the micro-filtration membrane so as to apply resistance to sperms passing through the L-shaped channel; compared with the prior art, by further screening and optimizing the obtained sperms, the quality and activity of the sperms reaching the outlet end of the L-shaped channel can be effectively improved, and the sperms with more natural pregnancy vitality can be screened out.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of assisted reproductive medical instruments, especially to a sperm optimization device. BACKGROUND

[0002] The test-tube baby technology is one of the main methods for treating infertility at present, and is mainly aimed at women with difficult ovulation and men with oligospermia, and the patients with oligospermia show low sperm quantity, low sperm motility and impaired sperm function, so as to fail to naturally fertilize ovum cells.

[0003] At present, there are two kinds of conventional semen optimization treatment methods, i.e. the upstream method and the gradient centrifugation method. The gradient centrifugation is to separate sperm and seminal plasma and remove impurities, and to separate viable sperm and non-viable sperm. However, during the process of optimizing and screening sperm by the density gradient centrifugation method, there are also poor quality sperm, and therefore further improvement is needed on this basis. UTILITY MODEL CONTENT

[0004] To solve the technical problems in the background art, the utility model provides a sperm optimization device.

[0005] To achieve the above-mentioned purposes, the utility model provides the following technical scheme:

[0006] A sperm optimization device, characterized in that it comprises:

[0007] A screening groove composed of a storage groove and an optimization groove, and the storage groove and the optimization groove are separated by a partition plate;

[0008] An L-shaped channel provided in the screening groove and composed of a first channel segment and a second channel segment, the inlet end of the L-shaped channel is located in the storage groove, the outlet end of the L-shaped channel is located in the optimization groove, and a microfiltration membrane is provided on the L-shaped channel;

[0009] A centrifugal impeller installed in the optimization groove, which can make the local water flow in the optimization groove circulate from the outlet end of the second channel segment to the microfiltration membrane, so as to exert resistance on the sperm passing through the L-shaped channel.

[0010] Preferably, a plurality of baffles are sequentially arranged in the extension direction of the first channel segment to increase the travel distance of the sperm from the inlet end to the outlet end of the L-shaped channel.

[0011] Preferably, the microfiltration membrane is specifically a polyvinylidene fluoride microfiltration membrane and is located at the junction position of the first channel segment and the second channel segment.

[0012] Preferably, the second channel segment is inclined to the horizontal plane, and the second channel segment is inclined upward in the direction away from the microfiltration membrane.

[0013] Preferably, a heating wire is further included, and the heating wire is arranged inside the L-shaped channel to make the temperature decrease in sequence from the inlet end of the L-shaped channel to the outlet end of the L-shaped channel.

[0014] Preferably, the screening groove and the L-shaped channel are made of titanium alloy.

[0015] Preferably, the first channel segment and the second channel segment of the L-shaped channel are equal in length and are 10-15 mm in length.

[0016] Compared with the prior art, the sperm preferred device has the following beneficial effects:

[0017] Compared with the prior art, the sperm preferred device can effectively improve the quality and activity of the sperm reaching the outlet end of the L-shaped channel by further screening and optimizing the obtained sperm, and can screen out sperm with higher natural conception activity. BRIEF DESCRIPTION OF DRAWINGS

[0018] Fig. 1 FIG. 1 is a structural schematic view of a sperm preferred device according to the present application;

[0019] Fig. 2 FIG. 2 is a position structure view of a baffle in the sperm preferred device according to the present application;

[0020] Fig. 3 FIG. 3 is a side view of a second channel segment in the sperm preferred device according to the present application.

[0021] In the drawings: 1-screening groove, 11-storage groove, 12-preferred groove, 13-baffle, 2-L-shaped channel, 21-first channel segment, 22-baffle, 23-second channel segment, 3-microfiltration membrane, 4-centrifugal impeller. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0023] As shown in FIG. 1, the present embodiment provides a sperm preferred device, which comprises: Figs. 1-3

[0024] The screening groove 1 is composed of the storage groove 11 and the preferred groove 12, and the storage groove 11 and the preferred groove 12 are separated by the baffle 13.

[0025] ​L-shaped channel 2 is located in screening tank 1 and consists of first channel section 21 and second channel section 23. The inlet end of L-shaped channel 2 is located in storage tank 11, and the outlet end of L-shaped channel 2 is located in optimization tank 12. A microfiltration membrane 3 is provided on L-shaped channel 2.

[0026] Centrifugal impeller 4 is installed in the preferred tank 12. Centrifugal impeller 4 can make the local water flow in the preferred tank 12 circulate along the outlet end of the second channel section 23 to the microfiltration membrane 3, so as to apply resistance to the sperm passing through the L-shaped channel 2.

[0027] Overall, semen washing solution is added to the storage tank 11 of the screening tank 1. The sperm that has undergone gradient centrifugation is placed into the storage tank 11 and the countdown begins. At the same time, the centrifugal impeller 4 is started. The sperm with good motility enter from the inlet end of the L-shaped channel 2 and exit from the outlet end of the L-shaped channel 2 to reach the optimization tank 12. When the sperm reach the junction of the first channel section 21 and the second channel section 23, the rotation of the centrifugal impeller 4 enables the water flow in a local area of ​​the optimization tank 12 to circulate along the outlet end of the second channel section 23 to the microfiltration membrane 3. This applies resistance to the sperm in the second channel section 23, screening the sperm while ensuring the activity of the sperm that reach the outlet end of the L-shaped channel 2. The microfiltration membrane 3 ensures water circulation while preventing the sperm from being discharged from the L-shaped channel 2 with the water flow.

[0028] The countdown time is 12-18 minutes. The specific time can be set according to the actual situation or the results obtained beforehand. There is no limit here.

[0029] like Figs. 1-2 As shown, in this embodiment, a plurality of baffles 22 are also included. The plurality of baffles 22 are arranged sequentially in the extension direction of the first channel segment 21 to increase the travel distance of sperm from the inlet end to the outlet end of the L-shaped channel 2.

[0030] Specifically, it also includes multiple baffles 22. By sequentially setting multiple baffles 22 in the extension direction of the first channel segment 21, the travel distance of sperm in the first channel segment 21 can be increased. By increasing the travel distance of sperm, sperm motility can be more accurately distinguished, and sperm with greater natural fertilization potential can be selected.

[0031] like Figs. 1-2 As shown, in this embodiment, the microfiltration membrane 3 is specifically a polyvinylidene fluoride microfiltration membrane and is located at the junction of the first channel segment 21 and the second channel segment 23.

[0032] Specifically, the microfiltration membrane 3 is a polyvinylidene fluoride microfiltration membrane, which has good chemical stability and mechanical strength, can ensure the quality of sperm, and can avoid the rupture of the polyvinylidene fluoride microfiltration membrane caused by the flow of water flow. In addition, the protein adsorption rate of the polyvinylidene fluoride microfiltration membrane is low, which can ensure the quality and purity of the filtered product when filtering substances containing proteins, thereby ensuring the quality of sperm.

[0033] As shown in Figs. 2-3 , in the present embodiment, the second channel segment 23 is inclined to the horizontal plane, and the second channel segment 23 is inclined upward in the direction away from the microfiltration membrane 3.

[0034] Specifically, when the sperm flows to the outlet end in the second channel segment 23, the second channel segment 23 is inclined upward in the direction away from the microfiltration membrane 3 under the resistance of the circulating flow of water flow, which can further increase the resistance of the sperm in the second channel segment 23 during the flow to the outlet end, and can further distinguish the sperm motility and select sperm with higher natural conception motility.

[0035] As shown in Figs. 1-2 , in the present embodiment, a heating wire is further included, which is arranged inside the L-shaped channel 2 so that the temperature decreases in sequence from the inlet end of the L-shaped channel 2 to the outlet end of the L-shaped channel 2.

[0036] Specifically, during the process of sperm flowing from the inlet end of the L-shaped channel 2 to the outlet end of the L-shaped channel 2, the temperature decreases in sequence. According to the cold-seeking characteristics of sperm, sperm will flow from the area with higher temperature to the area with lower temperature, which can play a certain guiding role in the process of screening sperm activity.

[0037] As shown in Figs. 1-2 , in the present embodiment, the selection tank 1 and the L-shaped channel 2 are made of titanium alloy material.

[0038] Specifically, the selection tank 1 and the L-shaped channel 2 are made of titanium alloy material, which has good biocompatibility and can provide a relatively safe physical and chemical environment for sperm during sperm selection.

[0039] As shown in Figs. 1-2 , in the present embodiment, the length of the first channel segment 21 and the second channel segment 23 of the L-shaped channel 2 is equal and is 10-15 mm.

[0040] Specifically, the length of the first channel segment 21 and the second channel segment 23 is 10-15 mm, which can ensure enough time for sperm with different motilities to be distinguished, and improve the quality and accuracy of sperm selection.

[0041] Of course, the utility model is not limited to the details of the above exemplary embodiments for those skilled in the art, and also includes the same or similar structures that can be realized in other specific forms without departing from the spirit or basic characteristics of the utility model. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-limiting, the scope of the utility model is defined by the appended claims rather than the above description, therefore all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the utility model. Any reference signs in the claims should not be regarded as limiting the claims involved.

[0042] In addition, it should be understood that, although the present specification is described in terms of embodiments, not every embodiment contains only one independent technical solution, and the description of the specification is only for the sake of clarity, those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that those skilled in the art can understand.

[0043] The technical, shape, structure parts not described in detail in the utility model are well-known technologies.

Claims

1. A spermatozoa optimizing device, characterized in that, The application relates to a sperm screening device. The device comprises a screening tank (1) which is composed of a storage tank (11) and a preferred tank (12), and the storage tank (11) and the preferred tank (12) are separated by a partition (13); an L-shaped channel (2) which is arranged in the screening tank (1) and is composed of a first channel section (21) and a second channel section (23), the inlet end of the L-shaped channel (2) is located in the storage tank (11), the outlet end of the L-shaped channel (2) is located in the preferred tank (12), and a microfiltration membrane (3) is arranged on the L-shaped channel (2); and a centrifugal impeller (4) which is arranged in the preferred tank (12) and can make the local water flow in the preferred tank (12) realize circular flow from the outlet end of the second channel section (23) to the microfiltration membrane (3) so as to exert resistance on the sperm passing through the L-shaped channel (2). A plurality of baffles (22) are arranged in the extension direction of the first channel section (21) in sequence so as to increase the travel distance of the sperm from the inlet end to the outlet end of the L-shaped channel (2). The microfiltration membrane (3) is specifically a polyvinylidene fluoride microfiltration membrane and is located at the joint position of the first channel section (21) and the second channel section (23).

2. The sperm-preferential device according to claim 1, characterized in that The second channel section (23) is arranged to be inclined to the horizontal plane and is arranged to be inclined upward in the direction away from the microfiltration membrane (3).

3. The sperm-preferential device according to claim 2, characterized in that A heating wire is arranged in the L-shaped channel (2) so that the temperature decreases in sequence from the inlet end of the L-shaped channel (2) to the outlet end of the L-shaped channel (2).

4. The sperm, preferably device, according to claim 1 or 2, characterized in that, The screening tank (1) and the L-shaped channel (2) are made of titanium alloy.

5. The sperm-preferential device according to claim 1, characterized in that The lengths of the first channel section (21) and the second channel section (23) of the L-shaped channel (2) are equal and are 10-15 mm.

6. The sperm-preferential device according to claim 1, characterized by ​ 7. The sperm-preferential device according to claim 1, characterized by ​

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