Bubble removing device for pharmaceutical preparation

Abstract

The utility model discloses a bubble removal device for pharmaceutical preparations, which relates to the technical field of pharmaceutical preparations and comprises a negative pressure tank, an exhaust pipe is fixedly connected to one side of the top of the negative pressure tank, a stirring motor is fixedly connected to the top of the negative pressure tank through a support, and a driving magnet is fixedly connected to the output end of the stirring motor. A mounting frame is fixedly connected to the top of the inner side of the negative pressure tank, a driven magnet is rotatably connected to the interior of the mounting frame, and the driving magnet and the driven magnet are composed of magnets which are annularly distributed at equal intervals. According to the bubble removing device for the pharmaceutical preparation, the stirring motor is used for driving the driving magnet to rotate, and the driven magnet synchronously rotates through the magnetic coupling structure, so that the central rod and the stirring wings are driven to rotate and stir, and meanwhile, the bubble gathering and separating process is effectively accelerated by means of a negative pressure environment formed in the negative pressure tank; and bubbles on the surface and in the liquid are quickly discharged.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of pharmaceutical preparations, specifically to a bubble removal device for pharmaceutical preparations. BACKGROUND

[0002] In the process of pharmaceutical preparations, the removal of bubbles is an important link, because bubbles can affect the stability, uniformity and bioavailability of drugs. In the process of pharmaceutical preparations, bubbles are prone to cause more residues during removal.

[0003] In order to overcome the above defects, the prior art (publication number: CN208081931U) discloses a bubble remover applied to biopharmaceuticals, which comprises a pouring body, supporting legs, a connecting head, universal wheels, a cover plate, a fan, an exhaust pipe, a separation head, a discharge hole, a conveying pipe, an inner pipe and a liquid outlet pipe. By installing a spiral conveying pipe inside the pouring body, the connecting head is connected with the external liquid inlet pipe during work. After the liquid enters the inside of the conveying pipe, it is conveyed to the top of the separation head. The diameter of the separation head is larger than that of the conveying pipe. The pressure inside the liquid is reduced, and the bubbles are emitted. As the liquid is discharged from the discharge hole, the fan quickly extracts the discharged bubbles from the pouring body. The pouring body does not accumulate gas, and bubbles cannot re-enter the inside of the liquid. The working efficiency is high. When the liquid is conveyed inside the conveying pipe, it shuttles back and forth between the conveying pipe and the inner pipe. The bubbles inside the liquid are separated, the separation efficiency is improved, and the bubble removal is more complete.

[0004] Although the prior art can overcome the above-mentioned deficiencies, there are still other problems in its operation process. During the process of removing bubbles from pharmaceutical preparations, the liquid inside the device is not stirred, which can cause bubbles to remain inside. UTILITY MODEL CONTENTS

[0005] The utility model aims at providing a bubble removal device for pharmaceutical preparations to solve the problem of bubble residue inside the device during the process of removing bubbles from pharmaceutical preparations in the above background technology.

[0006] To achieve the above object, the utility model provides the following technical scheme: a bubble removal device for pharmaceutical preparations, comprising a negative pressure tank, a suction pipe is fixedly connected to one side of the top of the negative pressure tank, and a stirring motor is fixedly connected to the top of the negative pressure tank through a support;

[0007] A driving magnet is fixedly connected to the output end of the stirring motor, and a mounting bracket is fixedly connected to the top inside of the negative pressure tank. A driven magnet is rotatably connected to the inside of the mounting bracket, and the driving magnet and the driven magnet are composed of magnets distributed at equal intervals in a ring shape;

[0008] The negative pressure tank is internally provided with a stirring structure, and a vibration structure is arranged between the stirring structure and the negative pressure tank.

[0009] Preferably, the stirring motor and the air extraction device are connected to each other, the stirring motor is in communication with the inside of the negative pressure tank, and an air pressure gauge is arranged on the top of the stirring motor.

[0010] Preferably, a sealing plate is fixedly connected to the middle of the top of the negative pressure tank, the sealing plate is made of plastic, and the sealing plate is arranged between the driving magnet and the driven magnet.

[0011] Preferably, a driving rod is fixedly connected to the bottom of the driven magnet, induction blocks are arranged on the two sides of the negative pressure tank in an up-down distribution, guide pipes are arranged on the two sides of the negative pressure tank in an up-down distribution, an electric control valve is arranged in the middle of each guide pipe, and the induction blocks and the electric control valves are electrically connected to each other.

[0012] Preferably, the stirring structure comprises a central rod arranged in the inside of the negative pressure tank, the central rod is a hollow structure, and the central rod is slidably connected to the outside of the driving rod.

[0013] Preferably, a spring is fixedly connected to the top of the central rod, the spring is arranged between the mounting frame and the top of the central rod, the driving rod is arranged in the spring, ring-shaped stirring wings are slidably connected to the outside of the central rod in an equidistant distribution, and the stirring wings are arranged in an equidistant distribution on the outside of the central rod.

[0014] Preferably, the vibration structure comprises a mounting block fixedly connected to the middle of the inside of the negative pressure tank, a rotating block is rotatably connected to the inside of the rotating block, the rotating block is slidably connected to the inside of the central rod in an upward extending manner, a vibration gear ring is fixedly connected to the lower end of the outside of the central rod, a fixed gear ring is fixedly connected to the outside of the top of the mounting block, and the vibration gear ring and the fixed gear ring are meshed with each other.

[0015] Compared with the prior art, the utility model has the advantages that:

[0016] The device utilizes the stirring motor to drive the rotation of the driving magnet, the driven magnet is synchronously rotated through the magnetic coupling structure, the rotation movement of the central rod and the stirring wings is driven, the bubble gathering and separation process is effectively accelerated in the negative pressure environment formed in the negative pressure tank during stirring, and the bubbles on the surface and in the inside of the liquid are rapidly discharged.

[0017] The meshing action between the vibration gear ring and the fixed gear ring causes the central rod to periodically vibrate up and down, the vibration and the rotation disturbance of the stirring wings are combined, and the separation efficiency of the small bubbles in the liquid is further improved. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 It is a three-dimensional structure schematic view of the utility model.

[0019] Figure 2 It is the cross section structure schematic view of negative pressure tank of the utility model;

[0020] Figure 3 It is the cross section structure schematic view of negative pressure tank of the utility model Figure 2 It is the enlarged structure schematic view of A place in the middle;

[0021] Figure 4 It is the drive magnet structure schematic view of the utility model;

[0022] Figure 5 It is the cross section structure schematic view of center pole of the utility model;

[0023] Figure 6 It is the vibration tooth ring structure schematic view of the utility model.

[0024] In the drawing: 1, negative pressure tank;2, suction pipe;3, stirring motor;4, drive magnet;5, mounting frame;6, driven magnet;7, sealing plate;8, drive rod;9, induction block;10, flow guide pipe;11, electric control valve;12, center pole;13, spring;14, stirring wing;15, mounting block;16, rotating block;17, vibration tooth ring;18, fixed tooth ring. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0026] Embodiment one: please refer to Figure 1 - Figure 6The utility model provides following technical scheme: a kind of bubble removal device of pharmaceutical preparation, including negative pressure tank 1, negative pressure tank 1 top side is fixedly connected with suction pipe 2, and negative pressure tank 1 top is fixedly connected with stirring motor 3 by support;Stirring motor 3 output end is fixedly connected with drive magnet 4, and negative pressure tank 1 inside top is fixedly connected with mounting bracket 5, mounting bracket 5 is rotatably connected with driven magnet 6 inside, and drive magnet 4 and driven magnet 6 are made of magnet of annular equidistant distribution;Stirring structure is installed in negative pressure tank 1, and vibration structure is equipped between stirring structure and negative pressure tank 1;Stirring motor 3 and suction equipment are connected with each other, and stirring motor 3 is communicated with inside of negative pressure tank 1, and stirring motor 3 top is installed with barometer;Negative pressure tank 1 top middle is fixedly connected with sealing plate 7, and sealing plate 7 is equipped as plastic structure, and sealing plate 7 is located in the middle of drive magnet 4 and driven magnet 6;Driven magnet 6 bottom is fixedly connected with drive rod 8, and negative pressure tank 1 both sides are fixedly connected with the inductive block 9 of distribution up and down, negative pressure tank 1 both sides are installed with the flow guide pipe 10 of distribution up and down, and electric control valve 11 is installed in each flow guide pipe 10 middle, and inductive block 9 and electric control valve 11 are electrically connected with each other.

[0027] When operation starts, liquid is injected into the inside through the flow guide pipe 10 on the top of the negative pressure tank 1, when the liquid level rises and contacts the inductive block 9, the two electrodes form an electrical connection through the liquid, the inductive block 9 controls the electric control valve 11 to close the top flow guide pipe 10, so as to stop liquid injection and avoid excessive liquid filling, at the same time, the flow guide pipe 10 at the lower end of the negative pressure tank 1 is in a closed state to ensure that the whole system is sealed.

[0028] Subsequently, the stirring motor 3 is started, the drive magnet 4 at the output end thereof rotates, since the drive magnet 4 and the driven magnet 6 on the mounting bracket 5 inside the negative pressure tank 1 form a magnetic coupling state through the annular equidistant distribution of magnets, the rotation of the drive magnet 4 drives the driven magnet 6 to rotate synchronously, so that the drive rod 8 installed at the bottom of the driven magnet 6 starts to rotate, the rotation of the drive rod 8 is further transmitted to the center rod 12, thereby driving the stirring wings 14 on the outside of the center rod 12 to rotate around the center rod 12, and the liquid in the negative pressure tank 1 is effectively stirred, at the same time, the suction pipe 2 is connected to the external suction equipment, after starting suction, a negative pressure environment is formed in the negative pressure tank 1, under the dual action of stirring and negative pressure, the bubbles on the surface and in the inside of the liquid are quickly separated and gathered, and are discharged through the negative pressure, so as to realize a high-efficiency bubble removal effect.

[0029] When the bubble removal is completed, the control system opens the electric control valve 11 at the lower end of the negative pressure tank 1, at this time, the lower end flow guide pipe 10 is in an open state, the treated liquid is discharged from the negative pressure tank 1, at the same time, air is injected in reverse through the air suction pipe 2, so that the pressure in the negative pressure tank 1 returns to the normal state, when the liquid level is lower than the sensing area of the sensing block 9, the electric control valve 11 will close the flow guide pipe 10 again, and new liquid is injected through the top flow guide pipe 10 to start the next bubble removal operation.

[0030] In the embodiment one, the stirring structure and the vibration structure are further disclosed, and the specific structure is as follows: the stirring structure comprises a center rod 12 installed in the negative pressure tank 1, and the center rod 12 is a hollow structure and is slidably connected to the outside of the driving rod 8; the spring 13 is fixedly connected to the top of the center rod 12, and the spring 13 is located between the mounting bracket 5 and the top of the center rod 12, and the driving rod 8 is located in the spring 13; the stirring wings 14 are slidably connected to the outside of the center rod 12 in a ring shape and equidistantly distributed, and the stirring wings 14 are equidistantly distributed on the outside of the center rod 12; the vibration structure comprises a mounting block 15 fixedly connected to the middle of the inside of the negative pressure tank 1, and the rotating block 16 is rotatably connected to the inside of the rotating block 16, and the rotating block 16 is slidably connected to the inside of the center rod 12 in a middle upward extending manner; the vibration gear ring 17 is fixedly connected to the outside of the lower end of the center rod 12, and the fixed gear ring 18 is fixedly connected to the outside of the top of the mounting block 15, and the vibration gear ring 17 and the fixed gear ring 18 are meshed with each other.

[0031] The stirring structure comprises a center rod 12 installed in the negative pressure tank 1, and the center rod is a hollow structure and is slidably connected to the outside of the driving rod 8, in the stirring process, the driven magnet 6 drives the driving rod 8 to rotate, at the same time, the driving rod 8 drives the center rod 12 to rotate in a coaxial manner through the sliding connection, the rotation of the center rod 12 is transmitted to the liquid through the stirring wings 14 uniformly distributed on the outside, so that the liquid is fully stirred.

[0032] The vibration gear ring 17 is fixedly installed on the outside of the lower end of the center rod 12, and the fixed gear ring 18 is fixedly connected to the top of the mounting block 15 in the middle of the negative pressure tank 1, when the center rod 12 rotates, the vibration gear ring 17 and the fixed gear ring 18 are meshed with each other, due to the design of the triangular inclined surface structure of the gear surface, during the rotation and contact of the two, periodic approaching and moving away from each other is generated, the mechanical action makes the vibration gear ring 17 drive the center rod 12 to vibrate up and down, at the same time, the spring 13 connected to the top of the center rod 12 is periodically compressed and released in the vibration process, so that the vibration is more stable and has a certain flexibility.

[0033] Under the vibration, the stirring wings 14 connected outside the central rod 12 not only rotate around the central axis, but also vibrate with the central rod 12, and at the same time, the stirring wings 14 produce a vortex-like disturbance effect on the liquid, the double action makes the micro-bubbles in the liquid gather and break faster, in addition, the vibration can promote the separation process of the liquid and the gas, and accelerate the bubbles to escape from the liquid, thereby significantly improving the bubble removal efficiency and the overall operation effect.

[0034] After the operation is completed, the treated liquid is still discharged by opening the lower end electric control valve 11, and at the same time, the new liquid is supplemented, so as to form a circulating work process.

[0035] In the description of the utility model, it needs to be explained that, unless there is definite provision and limitation, the terms "connected" and "connected" should be understood broadly, for example, it can be fixed connection, or detachable connection, or integral connection, it can be mechanical connection, or electrical connection, it can be direct connection, or indirect connection through intermediate medium. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0036] Although the utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, the technical solutions recorded in the foregoing embodiments can be modified, or part of the technical features can be replaced, any modification, equivalent replacement, improvement, etc. within the spirit and principles of the utility model should be included in the protection scope of the utility model.

Claims

1. A bubble removal device for pharmaceutical preparations, comprising a negative pressure tank (1), one side of the top of the negative pressure tank (1) is fixedly connected with an air extraction pipe (2), and the top of the negative pressure tank (1) is fixedly connected with a stirring motor (3) through a support; characterized in that The output end of the stirring motor (3) is fixedly connected with a driving magnet (4), and the inside top of the negative pressure tank (1) is fixedly connected with a mounting bracket (5), the inside of the mounting bracket (5) is rotatably connected with a driven magnet (6), and the driving magnet (4) and the driven magnet (6) are composed of magnets arranged in a ring shape at equal intervals; The inside of the negative pressure tank (1) is provided with a stirring structure, and the stirring structure and the negative pressure tank (1) are provided with a vibration structure.

2. The apparatus for removing bubbles from a pharmaceutical preparation according to claim 1, characterized by: The stirring motor (3) and the air extraction equipment are connected with each other, the inside of the stirring motor (3) communicates with the inside of the negative pressure tank (1), and the top of the stirring motor (3) is provided with an air pressure gauge.

3. The apparatus for removing bubbles from a pharmaceutical preparation according to claim 1, wherein: The middle of the top of the negative pressure tank (1) is fixedly connected with a sealing plate (7), the sealing plate (7) is made of plastic structure, and the sealing plate (7) is located between the driving magnet (4) and the driven magnet (6).

4. The apparatus for removing bubbles from a pharmaceutical preparation according to claim 1, wherein: The bottom of the driven magnet (6) is fixedly connected with a driving rod (8), and the two sides of the negative pressure tank (1) are fixedly connected with induction blocks (9) arranged in an up-down manner, the two sides of the negative pressure tank (1) are provided with guide pipes (10) arranged in an up-down manner, the middle of each guide pipe (10) is provided with an electric control valve (11), and the induction blocks (9) and the electric control valves (11) are electrically connected with each other.

5. The apparatus for removing bubbles from a pharmaceutical preparation according to claim 1, wherein: The stirring structure comprises a center rod (12) mounted in the inside of the negative pressure tank (1), the center rod (12) is provided with a hollow structure, and the center rod (12) is slidably connected to the outside of the driving rod (8) in the inside.

6. A bubble removal device for a pharmaceutical preparation according to claim 5, characterized in that: The top of the center rod (12) is fixedly connected with a spring (13), the spring (13) is located between the mounting bracket (5) and the top of the center rod (12), and the driving rod (8) is located in the inside of the spring (13), the outside of the center rod (12) is slidably connected with stirring wings (14) arranged in a ring shape at equal intervals, and the stirring wings (14) are arranged at equal intervals on the outside of the center rod (12) in an up-down manner.

7. The apparatus for removing bubbles from a pharmaceutical preparation according to claim 1, wherein: The vibration structure comprises a mounting block (15) fixedly connected to the inside of the negative pressure tank (1), a rotating block (16) rotatably connected in the inside of the rotating block (16), and the rotating block (16) extends upwardly in the inside of the center rod (12), the lower end of the center rod (12) is fixedly connected with a vibration gear ring (17), the top of the mounting block (15) is fixedly connected with a fixed gear ring (18) on the outside, and the vibration gear ring (17) and the fixed gear ring (18) are engaged with each other.

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