Temperature control type high-speed pulverizer for preparing Pinefibrate raw material medicine
By employing inert gas cooling and air circulation design in a temperature-controlled high-speed pulverizer, the problem of heat affecting drug properties during pulverization is solved, ensuring drug quality and stable operation.
Patent Information
- Application Number
- CN202520004821.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-02
- Publication Date
- 2026-02-17
- Estimated Expiration
- 2035-01-02
AI Technical Summary
During the pulverization of pemafibrate raw material, the heat generated by friction affects the drug's properties, leading to a decline in the quality of the finished drug.
A temperature-controlled high-speed pulverizer is used, which employs inert gas cooling and recovery components to cool the inert gas and accelerate air circulation with a fan, preventing excessive temperature and ensuring drug quality.
Effective temperature control during the pulverization process ensures drug quality, prevents high temperatures from affecting drug properties, and enables normal operation and powder collection.
Smart Images
Figure CN223915588U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the technical field of raw material medicine preparation, especially to a temperature control type high-speed pulverizer for preparing pemafibrate raw material medicine. BACKGROUND
[0002] When preparing pemafibrate medicine, the raw material needs to be pulverized, but in the process of pulverization, the raw material will continuously rub against the pulverizing blade, thereby generating a large amount of heat in the process of pulverization, which will affect the medicinal properties when the temperature reaches a certain degree, and finally may affect the quality of the finished medicine. UTILITY MODEL CONTENTS
[0003] The utility model aims at solving the problem that the raw material of medicinal materials continuously rubs against the pulverizing blade in the process of pulverization of the existing pulverizer, thereby generating a large amount of heat in the process of pulverization, which will affect the medicinal properties when the temperature reaches a certain degree, and finally may affect the quality of the finished medicine, and provides a temperature control type high-speed pulverizer for preparing pemafibrate raw material medicine.
[0004] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a temperature control type high-speed pulverizer for preparing pemafibrate raw material medicine, which comprises a pulverizing assembly, a cooling assembly is installed on one side of the lower end of the pulverizing assembly, and a recycling assembly is arranged on the upper end of the pulverizing assembly, the pulverizing assembly comprises a pulverizing tank, a feed hopper is fixedly connected to the lower bottom surface of the pulverizing tank, an installation plate is fixedly connected to the inner wall of the feed hopper, a grinding disc A is fixedly connected to the upper surface of the installation plate, a filter frame is arranged above the grinding disc A and is fixedly installed in the pulverizing tank, a motor is fixedly connected to the upper surface of the pulverizing tank, a stirring shaft is fixedly connected to the output end of the motor, the lower end of the stirring shaft penetrates through the pulverizing tank and extends into the interior thereof, the lower end of the stirring shaft movably penetrates through the filter frame and extends to the lower side thereof, pulverizing blades are fixedly connected to the outer surface of the stirring shaft, the pulverizing blades are arranged above the filter frame, the cooling assembly comprises an inert gas bottle body, and the inert gas bottle body is arranged on one side of the feed hopper.
[0005] Preferably, the recycling assembly comprises a recycling pipe, one end of the recycling pipe is communicated with the pulverizing tank, the other end of the recycling pipe is communicated with a recycling box, the recycling box is installed on the upper surface of the pulverizing tank, a box cover is rotatably connected to the upper end of the recycling box, a fan is fixedly connected to the inner wall of the recycling box, a filter screen is arranged on one side of the fan and in the interior of the recycling box.
[0006] The rate of air circulation in the interior of the pulverizing tank is accelerated, thereby cooling the interior thereof, and avoiding that the temperature is too high during accidental pulverization, thereby affecting the final quality of the medicine.
[0007] Preferably, the lower bottom surface of the feed hopper is fixedly connected with supporting legs, four groups of supporting legs are arranged, and a reinforcing rod is fixedly connected between every two groups of supporting legs, and a base plate is fixedly connected to the lower end of the supporting leg.
[0008] Support the whole device while increasing its stability, so that the whole device can run normally.
[0009] Preferably, the lower hopper bottom surface is provided with a discharge pipe, and the discharge pipe is provided with a valve.
[0010] For guiding the finished medicine powder, so as to facilitate its discharge from the hopper.
[0011] Preferably, the lower end of the stirring shaft is fixedly connected with a grinding disc B, and a plurality of discharge holes are formed in the grinding disc B.
[0012] For grinding the crushed medicine raw materials.
[0013] Preferably, the lower end of the stirring shaft is fixedly connected with a sweeping plate, and the filter frame corresponds to the sweeping plate.
[0014] For cleaning the crushed medicine debris, so that it can conveniently fall through the filter frame onto the grinding disc B.
[0015] Compared with the prior art, the utility model has the advantages of:
[0016] 1. The utility model discloses a temperature control type high-speed pulverizer for preparing pemafibrate raw medicine, which is characterized in that: a cooling assembly is arranged, after the inert gas bottle body is installed on the hopper, when the medicine raw materials are crushed, the inert gas in the inert gas bottle body is introduced into the hopper, and then the low-temperature inert gas is used for cooling the inside of the crushing tank, so that the quality of the medicine is prevented from being affected by the temperature generated during crushing.
[0017] 2. The utility model discloses a temperature control type high-speed pulverizer for preparing pemafibrate raw medicine, which is characterized in that: a recycling assembly is arranged, air circulation in the crushing tank is accelerated by the suction force generated by the fan, so that the inside of the crushing tank is cooled, the temperature fluctuation in the inside of the crushing tank is not large, and the medicine powder in the air is collected through the filter screen, so that the whole device can run normally. DETAILED DESCRIPTION
[0018] Figure 1 It is a whole structure schematic view of the utility model;
[0019] Figure 2 It is a whole structure schematic view of the utility model pulverizing assembly;
[0020] Figure 3 It is a cross-sectional view of the utility model pulverizing assembly;
[0021] Figure 4 It is a cross-sectional view of the utility model recycling assembly;
[0022] Figure 5 It is partial integral structure diagram of the pulverizing assembly of the utility model;
[0023] Legend:
[0024] 1, pulverizing assembly;11, pulverizing jar;12, hopper;121, supporting leg;122, reinforcing rod;123, pad;13, discharge pipe;131, valve;14, mounting plate;15, grinding disc A;16, filter frame;17, motor;18, stirring shaft;181, grinding disc B;182, discharging hole;183, sweeping plate;19, pulverizing blade;2, cooling assembly;21, inert gas bottle body;3, recycling assembly;31, recycling pipe;32, recycling box;33, box cover;34, fan;35, filter screen. DETAILED DESCRIPTION
[0025] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.
[0026] In the description of the utility model, it should be explained that the directions or position relations indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and the like are the directions or position relations shown in the drawings, which are only for the convenience of describing the utility model and simplifying the description, and are not intended to indicate or imply that the devices or elements referred to must have a particular direction, be constructed and operated in a particular direction, and therefore cannot be understood as a limitation on the utility model;The terms "first", "second", "third" are only for the purpose of description, and cannot be understood as indicating or implying relative importance, in addition, unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connection" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected;It can be mechanical connection, or electrical connection;It can be directly connected, or indirectly connected through an intermediate medium, or the communication between two elements. For those skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.
[0027] Reference Figures 1-5The utility model provides a kind of embodiment of the utility model: a kind of warm control formula high-speed pulverizer of pemetrexed raw material preparation, including pulverization subassembly 1, and the lower end one side of pulverization subassembly 1 is equipped with cooling assembly 2, and the upper end of pulverization subassembly 1 is provided with recycling component 3, and pulverization subassembly 1 includes pulverizing tank 11, and the upper end of pulverizing tank 11 is provided with feeding opening, to facilitate the pemetrexed raw material into pulverizing tank 11 subsequent operation, and the lower bottom of pulverizing tank 11 is fixedly connected with hopper 12, and the pemetrexed of processing completion is conveniently discharged and is collected, and the inner wall of hopper 12 is fixedly connected with mounting plate 14, and the upper surface of mounting plate 14 is fixedly connected with grinding disc A 15, and grinding disc B 181 is cooperated to carry out grinding operation to the pemetrexed raw material after being pulverized, and the upper side of grinding disc A 15 is equipped with filter frame 16, and the pemetrexed raw material after being pulverized is filtered, so that the qualified pulverization falls on grinding disc B 181 to facilitate subsequent operation, and filter frame 16 is fixedly installed in pulverizing tank 11.
[0028] The upper surface of pulverizing tank 11 is fixedly connected with motor 17, and the output end of motor 17 is fixedly connected with stirring shaft 18, and the stirring shaft 18 is rotated by motor 17, so that it can normally work, and the lower end of stirring shaft 18 penetrates through pulverizing tank 11 and extends to its inside, and the lower end of stirring shaft 18 movably penetrates through filter frame 16 and extends to its lower side, and the outer surface of stirring shaft 18 is fixedly connected with pulverizing blade 19, to carry out pulverization operation to the pemetrexed raw material, and the pulverizing blade 19 is arranged above filter frame 16, and cooling assembly 2 includes inert gas bottle body 21, and inert gas bottle body 21 is arranged on one side of hopper 12, and low-temperature inert gas is introduced into hopper 12, and then rises to carry out cooling operation to pulverizing tank 11, to ensure that the inside of pulverizing tank 11 will not be affected by the temperature that is too high to influence the quality of medicinal materials finally.
[0029] Recycling component 3 includes recovery pipe 31, and one end of recovery pipe 31 is communicated with pulverizing tank 11, and the other end of recovery pipe 31 is communicated with recovery tank 32, and recovery tank 32 is installed on the upper surface of pulverizing tank 11, and box cover 33 is rotatably connected to the upper end of recovery tank 32, and fan 34 is fixedly connected to the inner wall of recovery tank 32, and filter screen 35 is arranged on one side of fan 34, and filter screen 35 is arranged in the inside of recovery tank 32, and suction force is generated by fan 34, and then the flow rate of air in the inside of pulverizing tank 11 is accelerated, so that low-temperature inert gas carries the heat generated during pulverization, to ensure the quality of medicinal material raw materials, and filter screen 35 is used to filter and recover medicinal powder.
[0030] The lower bottom surface of the feeding hopper 12 is fixedly connected with supporting legs 121, four groups of supporting legs 121 are arranged, and a reinforcing rod 122 is fixedly connected between every two groups of supporting legs 121, the lower end of the supporting leg 121 is fixedly connected with a pad plate 123, the whole device can work normally, the lower bottom surface of the feeding hopper 12 is provided with a discharge pipe 13, the discharge pipe 13 is provided with a valve 131, the medicinal material powder in the feeding hopper 12 is guided to work, so that the processed medicinal material powder is conveniently collected, the lower end of the stirring shaft 18 is fixedly connected with a grinding disc B 181, a plurality of feeding holes 182 are formed in the grinding disc B 181, the crushed medicinal material raw materials can fall on the grinding disc A 15, the grinding disc A 15 is matched with the grinding disc B 181, the crushed medicinal material is ground, and the diameter of the grinding disc B 181 is consistent with the inner diameter of the crushing tank 11, so that the crushed medicinal material cannot directly fall into the feeding hopper 12 and is not aligned for grinding work, the lower end of the stirring shaft 18 is fixedly connected with a sweeping plate 183, the filter frame 16 corresponds to the sweeping plate 183, and the medicinal material raw materials falling on the filter frame 16 are swept to work, so that they can quickly pass through the filter frame 16.
[0031] Working principle: first, before the pemafibrate raw material crushing operation, the inert gas bottle body 21 filled with low-temperature inert gas is installed on the feeding hopper 12, the low-temperature inert gas is introduced into the feeding hopper 12, then the pemafibrate raw material to be processed is added to the crushing tank 11, and the motor 17 is started to drive the stirring shaft 18 to rotate, so that the crushing blade 19 crushes the pemafibrate raw material, the crushed pemafibrate raw material falls on the filter frame 16, the qualified crushed pieces fall on the grinding disc B 181 through the filter frame 16, then fall between the grinding disc B 181 and the grinding disc A 15 through the feeding hole 182, and are ground by the grinding disc B 181 and the grinding disc A 15.
[0032] In this process, the fan 34 also operates to generate suction, accelerates the flow rate of air in the crushing tank 11, so that the inert gas carries away the heat generated during grinding and crushing, ensures that the whole device can normally work, and under the action of the filter screen 35, the powder of the pemafibrate raw material in the air can also be filtered, which is convenient for collecting later, and finally the processed pemafibrate raw material powder is collected.
[0033] Finally, it should be noted that: the above only describes the preferred embodiments of the present application, and is not intended to limit the present application, although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part of the technical features, any modification, equivalent replacement, improvement, etc. within the spirit and principles of the present application shall be included in the protection scope of the present application.
Claims
1. A temperature-controlled high-speed pulverizer for preparing pemafibrate raw material, comprising a pulverizing component (1), a cooling component (2) installed on one side of the lower end of the pulverizing component (1), and a recovery component (3) provided on the upper end of the pulverizing component (1), characterized in that: The crushing assembly (1) includes a crushing tank (11), a feeding hopper (12) is fixedly connected to the bottom surface of the crushing tank (11), an mounting plate (14) is fixedly connected to the inner wall of the feeding hopper (12), a grinding disc A (15) is fixedly connected to the upper surface of the mounting plate (14), a filter frame (16) is provided above the grinding disc A (15), the filter frame (16) is fixedly installed inside the crushing tank (11), and a motor (17) is fixedly connected to the upper surface of the crushing tank (11). 17) An agitator shaft (18) is fixedly connected to the output end. The lower end of the agitator shaft (18) extends through the pulverizing tank (11) and into it. The lower end of the agitator shaft (18) extends through the filter frame (16) and into its lower side. A pulverizing blade (19) is fixedly connected to the outer surface of the agitator shaft (18). The pulverizing blade (19) is located above the filter frame (16). The cooling component (2) includes an inert gas bottle body (21). The inert gas bottle body (21) is located on one side of the feed hopper (12).
2. The temperature-controlled high-speed pulverizer for preparing pemafibrate active pharmaceutical ingredient according to claim 1, characterized in that: The recycling component (3) includes a recycling pipe (31), one end of which is connected to the crushing tank (11), and the other end of which is connected to the recycling box (32). The recycling box (32) is installed on the upper surface of the crushing tank (11). A box cover (33) is rotatably connected to the upper end of the recycling box (32). A fan (34) is fixedly connected to the inner wall of the recycling box (32). A filter screen (35) is provided on one side of the fan (34). The filter screen (35) is located inside the recycling box (32).
3. The temperature-controlled high-speed pulverizer for preparing pemafibrate active pharmaceutical ingredient according to claim 1, characterized in that: The bottom surface of the hopper (12) is fixedly connected to a support leg (121). There are four sets of support legs (121), and a reinforcing rod (122) is fixedly connected between every two sets of support legs (121). A pad (123) is fixedly connected to the lower end of the support leg (121).
4. The temperature-controlled high-speed pulverizer for preparing pemafibrate active pharmaceutical ingredient according to claim 1, characterized in that: A discharge pipe (13) is installed on the bottom surface of the hopper (12), and a valve (131) is installed on the discharge pipe (13).
5. The temperature-controlled high-speed pulverizer for preparing pemafibrate active pharmaceutical ingredient according to claim 1, characterized in that: The lower end of the stirring shaft (18) is fixedly connected to a grinding disc B (181), and multiple sets of feeding holes (182) are opened on the grinding disc B (181). The grinding disc A (15) is matched with the grinding disc B (181).
6. The temperature-controlled high-speed pulverizer for preparing pemafibrate active pharmaceutical ingredient according to claim 1, characterized in that: A sweeping plate (183) is fixedly connected to the lower end of the stirring shaft (18), and the filter frame (16) corresponds to the sweeping plate (183).