Membrane uncovering mechanism for membrane

Abstract

The utility model relates to the technical field of biochip manufacturing equipment, in particular to a membrane uncovering mechanism for a membrane, which comprises a working table, a sliding frame and a clamping jaw assembly, the working table is provided with a waste material port, the sliding frame is horizontally and slidably mounted on the working table through a sliding component, and the clamping jaw assembly is arranged on the working table. The clamping jaw assembly is installed on the sliding frame in a lifting mode through a lifting assembly, a clamping jaw used for uncovering a film is arranged below the clamping jaw assembly, and after the film is uncovered, the clamping jaw horizontally slides and moves to the waste material opening through the sliding frame to discard the PDMS layer. According to the film uncovering mechanism, through cooperation of the sliding assembly, the lifting assembly, the clamping jaw assembly and the like, automatic operation of the film uncovering process can be achieved, the film uncovering efficiency is improved, and damage to the substrate is avoided.

Description

Technical Field

[0001] This utility model relates to the field of biochip manufacturing equipment technology, specifically a membrane peeling mechanism for membranes. Background Technology

[0002] A biochip is a technological platform that immobilizes biomolecules (such as DNA, RNA, proteins, and cells) in the form of a microarray on a substrate (such as a glass slide, silicon wafer, or nylon membrane), enabling high-throughput, rapid, and parallel analysis of biological samples. The main techniques for immobilizing biomolecules on substrates include covalent bonding, microarray spotting, and in-situ synthesis. The principle of covalent bonding is that biomolecules form covalent bonds with active groups on the substrate (the substrate surface is pre-modified chemically to acquire specific active groups, such as amino or aldehyde groups) through chemical reactions, thereby stably immobilizing them on the substrate.

[0003] In the biochip manufacturing process, the covalent bonding process of biomolecules involves first aligning and bonding a PDMS layer with printed channels to a substrate (forming a film). Then, biomolecules are drawn through the channels of the PDMS layer using a suction method, thereby immobilizing the biomolecules onto the substrate. After the biomolecules are immobilized, the PDMS layer needs to be peeled off and discarded. The substrate then undergoes post-processing steps such as soaking, washing, drying, and fence bonding.

[0004] Currently, the overall fabrication process of biochips is mostly done manually. When peeling off the membrane, the membrane is held by hand and PDMS is peeled off and discarded with tweezers. This is inefficient and can easily contaminate the substrate. Moreover, the substrate is thin and brittle, and peeling off the membrane by hand can easily cause uneven stress on the substrate, leading to damage. Summary of the Invention

[0005] To address the aforementioned problems, this utility model provides a film-unwrapping mechanism for films, which enables automated film-unwrapping processes, improving unwrapping efficiency and product qualification rate. The technical solution adopted by this utility model is as follows:

[0006] A film peeling mechanism for diaphragms includes a worktable on which a diaphragm is placed, a slide, and a gripper assembly. The worktable is provided with a waste outlet. The slide is horizontally mounted on the worktable via a sliding assembly. The gripper assembly is vertically mounted on the slide via a lifting assembly. A gripper for peeling the diaphragm is provided below the gripper assembly. After peeling the diaphragm, the gripper slides horizontally along the slide to the waste outlet to discard the PDMS layer.

[0007] The above-mentioned membrane peeling mechanism has a placement platform on the worktable, on which the membrane is placed. A negative pressure component is provided below the worktable, and the negative pressure component is connected to the placement platform to adsorb or release the membrane.

[0008] The membrane peeling mechanism described above has a groove on the placement platform for storing the membrane, and a through hole in the groove to connect to the negative pressure component.

[0009] The above-mentioned film-removing mechanism includes a sliding assembly comprising a guide rail, a rack, a stepper motor, and a sliding limit switch for limiting the travel of the slide. The guide rail, rack, and sliding limit switch are respectively mounted on the worktable. The slide is slidably connected to the guide rail below. The stepper motor is mounted on the slide and its output shaft end is equipped with a gear that meshes with the rack.

[0010] The above-mentioned film peeling mechanism includes a lifting assembly comprising a linear lifting module and a lifting limit switch for limiting the stroke of the gripper assembly. The lifting limit switch and the linear lifting module are respectively installed on the front side of the carriage, and the gripper assembly is installed on the slide of the linear lifting module.

[0011] The beneficial effects of this utility model are as follows: the film peeling mechanism, through the cooperation of sliding components, lifting components, and gripper components, can realize the automated operation of the film peeling process, improve the film peeling efficiency, and avoid damage to the substrate. Attached Figure Description

[0012] Figure 1 and Figure 2 This is a schematic diagram of the overall structure of an embodiment of the present utility model;

[0013] Figure 3 This is a schematic diagram of the gripper peeling state according to an embodiment of the present invention;

[0014] Figure 4 This is a schematic diagram of the placement platform structure according to an embodiment of the present utility model.

[0015] In the diagram: 1 is the worktable, 2 is the guide rail, 3 is the rack, 4 is the stepper motor, 5 is the carriage, 6 is the linear lifting module, 7 is the gripper assembly, 8 is the gripper, 9 is the placement platform, 10 is the PDMS layer, 11 is the photoelectric limit switch I, 12 is the photoelectric limit switch II, 13 is the base, and 14 is the waste outlet. Detailed Implementation

[0016] The technical solution of this utility model will be described in detail below with reference to the accompanying drawings. The following embodiments are illustrative and intended to provide further explanation of this application. Unless otherwise specified, the electrical control system of this invention (such as various drive components, actuators, etc.) employs conventional technology, and all technical terms used have the same meaning as commonly understood by those skilled in the art to which this application pertains. It should be noted that the terminology used is only for describing specific embodiments and is not intended to limit the scope of this application.

[0017] This utility model relates to a membrane peeling mechanism for diaphragms, see reference. Figures 1 to 3The system includes a worktable 1 for holding a membrane sheet, a U-shaped carriage 5, and a gripper assembly 7. The membrane sheet includes an upper PDMS layer 10 and a lower substrate 13. The worktable 1 has a waste outlet 14. The carriage 5 is horizontally slidable on the worktable 1 via a sliding assembly. The gripper assembly 7 is vertically slidable on the carriage 5 via a lifting assembly. A gripper 8 for removing the membrane is located below the gripper assembly 7. After removing the membrane, the gripper 8 slides horizontally along the carriage 5 to the waste outlet 14 to discard the PDMS layer 10. Figure 3 As shown, the gripper assembly 7 can be a commercially available electric gripper or a pneumatic gripper. The gripping end of the gripper 8 is wedge-shaped, and the PDMS layer 10 is made of a soft rubber-like material. Therefore, when the gripper 8 retracts, it can accurately and quickly peel off and clamp the PDMS layer 10.

[0018] Furthermore, such as Figure 4 As shown, the workbench 1 is equipped with a placement platform 9, which has a groove for storing the membrane. A negative pressure assembly (a conventional installation structure and product, therefore not shown in the attached diagram) is installed below the workbench 1. The groove has a through hole to connect to the suction port of the negative pressure assembly, thus allowing the membrane to be adsorbed or released. When the membrane is peeled off, the negative pressure assembly activates to adsorb the substrate 13 of the membrane. The grippers 8 peel off the PDMS layer 10 and maintain the clamping state. The negative pressure assembly can be a commercially available vacuum generator, which has a compact structure, is easy to install, and provides uniform and stable adsorption force on the substrate 13.

[0019] Specifically, the sliding assembly includes a guide rail 2, a rack 3, a stepper motor 4, and a sliding limit switch for limiting the travel of the carriage 5. The guide rail 2, rack 3, and sliding limit switch are respectively mounted on the worktable 1. The carriage 5 is slidably connected to the guide rail 2 from below. The stepper motor 4 is mounted on the carriage 5, and its output shaft end is equipped with a gear that meshes with the rack 3. The sliding limit switch is a conventional photoelectric limit switch I11. Correspondingly, a photoelectric sensor is installed on the carriage 5. When the carriage 5 slides to the designated position and triggers the photoelectric limit switch I11, the stepper motor 4 reverses direction.

[0020] Specifically, the lifting assembly includes a linear lifting module 6 and a lifting limit switch for limiting the stroke of the gripper assembly 7 (limiting the minimum descent position to prevent the gripper 8 from colliding with the placement platform 9). The lifting limit switch and the linear lifting module 6 are respectively installed on the front side of the slide 5, and the gripper assembly 7 is installed on the slide of the linear lifting module 6. The lifting limit switch is a conventional photoelectric limit switch II12. Correspondingly, a photoelectric sensor is set on the slide of the linear lifting module 6 or the gripper assembly 7. When the gripper assembly 7 slides to the position and triggers the photoelectric limit switch II12, the linear lifting module 6 reverses its direction.

[0021] The above are merely preferred embodiments of this application. It should be noted that those skilled in the art can make various changes or improvements without departing from the principles of this application, and these changes or improvements should also be considered within the scope of protection of this application.

Claims

1. A membrane peeling mechanism, characterized in that: The device includes a worktable (1) on which the film is placed, a carriage (5) and a gripper assembly (7). The worktable (1) is provided with a waste port (14). The carriage (5) is horizontally mounted on the worktable (1) via a sliding assembly. The gripper assembly (7) is vertically mounted on the carriage (5) via a lifting assembly. A gripper (8) for peeling the film is provided below the gripper assembly (7). After peeling the film, the gripper (8) moves horizontally to the waste port (14) via the carriage (5) to discard the PDMS layer (10).

2. The membrane peeling mechanism according to claim 1, characterized in that: The workbench (1) is provided with a placement platform (9), and the membrane is placed on the placement platform (9). A negative pressure component is provided below the workbench (1), and the negative pressure component is connected to the placement platform (9) to adsorb or release the membrane.

3. The membrane peeling mechanism according to claim 2, characterized in that: The placement platform (9) is provided with a groove for storing the diaphragm, and the groove is provided with a through hole to connect to the negative pressure component.

4. The membrane peeling mechanism according to claim 1, characterized in that: The sliding assembly includes a guide rail (2), a rack (3), a stepper motor (4), and a sliding limit switch for limiting the travel of the carriage (5). The guide rail (2), rack (3), and sliding limit switch are respectively mounted on the worktable (1). The carriage (5) is slidably connected to the guide rail (2) below. The stepper motor (4) is mounted on the carriage (5), and its output shaft end is equipped with a gear that meshes with the rack (3).

5. The membrane peeling mechanism according to claim 1, characterized in that: The lifting assembly includes a linear lifting module (6) and a lifting limit switch for limiting the travel of the gripper assembly (7). The lifting limit switch and the linear lifting module (6) are respectively installed on the front side of the slide (5), and the gripper assembly (7) is installed on the slide of the linear lifting module (6).

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