Centrifugal mechanism of full-automatic liquid-based cell flaking and dyeing all-in-one machine

By combining a motor-driven sprocket transmission system with an ultrasonic transducer, the problem of traditional centrifugation mechanisms being unable to effectively clean the inner walls and bottoms of test tubes is solved, achieving a highly efficient cleaning effect and ensuring the accuracy of liquid-based cell preparation and staining.

CN223931619UActive Publication Date: 2026-02-24SHENZHEN RONGYI MEDICAL EQUIPMENT CO LTD
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Patent Information

Application Number
CN202520342208.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-28
Publication Date
2026-02-24
Estimated Expiration
2035-02-28

AI Technical Summary

Technical Problem

The centrifugation mechanism of traditional liquid-based cell preparation and staining machines cannot effectively remove stubborn stains and cell residues from the inner wall and bottom of test tubes, affecting the quality of subsequent liquid-based cell preparation and staining and leading to inaccurate test results.

Method used

The motor-driven sprocket transmission system rotates the cleaning rod, and the ultrasonic transducer generates high-frequency vibrations to form microbubbles to remove stubborn stains and cell residues, achieving highly efficient cleaning by combining physical cleaning methods.

Benefits of technology

It significantly improved the cleaning effect on the inner wall and bottom of the test tube, ensuring the accuracy of subsequent liquid-based cell preparation and staining operations, and improving the quality of test results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of medical instruments, and discloses a centrifugal mechanism of a full-automatic liquid-based cell slide-making and dyeing all-in-one machine, which comprises a liquid-based cell slide-making and dyeing all-in-one machine body, and a top cover is hinged on the outer wall of the liquid-based cell slide-making and dyeing all-in-one machine body. The inner wall of the liquid-based cell slide preparation and dyeing all-in-one machine body is slidably connected with a sedimentation cabin, a test tube is placed at the top of the sedimentation cabin, the outer wall of a top cover is rotatably connected with a gear, the outer wall of the gear is fixedly connected with a cleaning rod, and the inner wall of the top cover is fixedly connected with a sealing ring plate; a rotating disc is slidably connected into the inner wall of the sealing ring plate. According to the cleaning device, the ultrasonic transducer at the bottom end of the cleaning rod is matched with physical cleaning of the cleaning rod, stubborn stains and cell residues on the inner wall and the bottom of a test tube can be efficiently removed, the cleaning effect is remarkably improved, it is guaranteed that a sample is not interfered by impurities in subsequent liquid-based cell preparation dyeing operation, and the detection accuracy is improved.
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Description

Technical Field

[0001] This utility model relates to the field of medical devices, and in particular to the centrifugation mechanism of a fully automated liquid-based cell preparation and staining machine. Background Technology

[0002] The centrifugation mechanism of the fully automated liquid-based cell slide preparation and staining machine is a key component in the liquid-based cell detection process. This centrifugation mechanism mainly consists of the machine body, top cover, sedimentation chamber, test tubes, gears, cleaning rod, sealing ring plate, turntable, rotating ring, connecting plate, and other parts. Through the coordinated operation of these components, it achieves operations such as cleaning the test tubes and preparing and staining the samples.

[0003] In existing technologies, the centrifugation mechanism of a liquid-based cell preparation and staining machine plays a crucial role in the cell detection workflow. The operator first places the test tube containing the cell sample on top of the settling chamber, then closes the top cover and starts the equipment. The centrifugation mechanism begins operating to process the sample, including centrifugation, slide preparation, and staining, to obtain cell sample slides that meet the detection requirements.

[0004] However, traditional cleaning methods cannot effectively remove stubborn stains and cell residues from the inner wall and bottom of test tubes, causing the samples to be interfered with by impurities, affecting the quality of subsequent liquid-based cell preparation and staining, and thus reducing the accuracy of test results. To address this issue, a centrifugation mechanism in a fully automated liquid-based cell preparation and staining machine is proposed. Utility Model Content

[0005] To overcome the above shortcomings, this utility model provides a centrifugation mechanism for a fully automated liquid-based cell preparation and staining machine, which aims to solve the problem in the prior art where samples are affected by impurities, thus affecting the quality of subsequent liquid-based cell preparation and staining.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a centrifugation mechanism for a fully automatic liquid-based cell preparation and staining machine, comprising a liquid-based cell preparation and staining machine body, a top cover hinged to the outer wall of the liquid-based cell preparation and staining machine body, a sedimentation chamber slidably connected to the inner wall of the liquid-based cell preparation and staining machine body, a test tube placed on the top of the sedimentation chamber, a gear rotatably connected to the outer wall of the top cover, a cleaning rod fixedly connected to the outer wall of the gear, a sealing ring plate fixedly connected to the inner wall of the top cover, a turntable slidably connected to the inner wall of the sealing ring plate, a connecting plate inserted into the inner walls of the turntable and the sealing ring plate, a turntable inserted into the outer wall of the connecting plate, a motor fixedly connected to the top outer wall of the liquid-based cell preparation and staining machine body, a first sprocket fixedly connected to the output end of the motor, and a second sprocket fixedly connected to the top outer wall of the turntable.

[0007] As a further description of the above technical solution: an ultrasonic transducer is fixedly connected to the bottom end of the cleaning rod.

[0008] As a further description of the above technical solution: the outer wall of the rotating ring is slidably connected to the inner wall of the turntable.

[0009] As a further description of the above technical solution: the rotating ring is rotatably connected to a second connecting rod, and the second connecting rod is also fixedly connected to the outer wall of the turntable.

[0010] As a further description of the above technical solution: the outer walls of the first sprocket and the second sprocket are connected by chain drive.

[0011] As a further description of the above technical solution: a first connecting rod is rotatably connected to the outer wall of the turntable, and the first connecting rod is also fixedly connected to the outer wall of the top of the top cover.

[0012] As a further description of the above technical solution: the cleaning rod is adapted to the size of the test tube.

[0013] As a further description of the above technical solution: the outer wall of the gear is meshed with a toothed ring, and the top of the toothed ring is fixedly connected to the bottom of the rotating ring.

[0014] This utility model has the following beneficial effects:

[0015] 1. In this utility model, a motor drives a first sprocket, which in turn drives a second sprocket via a chain, causing the rotating ring to rotate. The toothed ring at the bottom of the rotating ring drives a gear to rotate, causing a cleaning rod fixed to the outer wall of the gear to physically clean the inner wall of the test tube. At the same time, an ultrasonic transducer at the bottom of the cleaning rod generates high-frequency vibrations, forming microbubbles in the liquid. The bursting of these bubbles generates a powerful impact force, which, in conjunction with the physical cleaning of the cleaning rod, can efficiently remove stubborn stains and cell residues from the inner wall and bottom of the test tube, significantly improving the cleaning effect and ensuring that the sample is not interfered with by impurities during subsequent liquid-based cell preparation and staining operations, thereby improving the accuracy of detection.

[0016] 2. In this utility model, the turntable and the sealing ring plate are slidably connected, and the rotating ring and the turntable are rotatably connected. The two can achieve different connection states through the connecting plate. When the connecting plate is inserted, the rotation of the rotating ring can drive the sealing ring plate to rotate together, and the relative position of the cleaning rod can be adjusted according to actual needs. When the connecting plate is not inserted, the rotating ring rotates independently. In addition, the sedimentation chamber is slidably connected to the inner wall of the liquid-based cell preparation and staining machine. After the test tube cleaning is completed, the sedimentation chamber can slide down for subsequent slide preparation operations. This flexible structural design enhances the adaptability of the equipment in different working scenarios and meets diverse experimental needs. Attached Figure Description

[0017] Figure 1This is a front view of the centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine proposed in this utility model.

[0018] Figure 2 This is a top view of the centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine proposed in this utility model;

[0019] Figure 3 The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine proposed in this utility model Figure 1 Enlarged view of point A in the middle;

[0020] Figure 4 This is a rear view of the centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine proposed in this utility model.

[0021] Legend:

[0022] 1. Liquid-based cell preparation and staining machine body; 2. Top cover; 3. Settling chamber; 4. Test tube; 5. Sealing ring plate; 6. First connecting rod; 7. Gear ring; 8. Gear; 9. Cleaning rod; 10. Ultrasonic transducer; 11. Second connecting rod; 12. Motor; 13. First sprocket; 14. Second sprocket; 15. Chain; 16. Rotary ring; 17. Connecting plate; 18. Turntable. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Reference Figure 1 - Figure 3This utility model provides an embodiment of a centrifugation mechanism for a fully automatic liquid-based cell preparation and staining machine, comprising a machine body 1, a top cover 2 hinged to the outer wall of the machine body 1, a sedimentation chamber 3 slidably connected to the inner wall of the machine body 1, the sedimentation chamber 3 being capable of transferring and settling slides, a test tube 4 placed on the top of the sedimentation chamber 3 for carrying cells, a gear 8 rotatably connected to the outer wall of the top cover 2 for a limiting effect, and a cleaning rod 9 fixedly connected to the outer wall of the gear 8, the rotation of the gear 8 driving the cleaning rod 9 to move forward. The top cover 2 is rotated, and a sealing ring plate 5 is fixedly connected to the inner wall of the top cover 2, which has a sealing effect. A turntable 18 is slidably connected to the inner wall of the sealing ring plate 5, and the turntable 18 can rotate in the sealing ring plate 5. A rotating ring 16 is rotatably connected to the top of the turntable 18, and the rotating ring 16 can rotate in the turntable 18. A connecting plate 17 is inserted into the inner wall of the sealing ring plate 5, and the rotating ring 16 is inserted into the outer wall of the connecting plate 17. The connecting plate 17 acts as a connector. When inserted, the rotation of the rotating ring 16 can drive the sealing ring plate 5 to rotate together. When not inserted, the rotating ring 16 rotates alone.

[0025] Reference Figure 2 - Figure 4 An ultrasonic transducer 10 is fixedly connected to the bottom of the cleaning rod 9. The ultrasonic transducer 10 generates high-frequency vibrations, which can generate tiny bubbles in the liquid. When the bubbles burst, they generate a strong impact force, which helps to remove stubborn stains and cell residues that are difficult to clean from the inner wall and bottom of the test tube 4. This works in conjunction with the physical cleaning action of the cleaning rod 9 to form a synergistic effect and significantly enhance the cleaning effect. The outer wall of the rotating ring 16 is slidably connected to the inner wall of the turntable 18. The outer wall of the gear 8 is meshed with a toothed ring 7. The rotation of the toothed ring 7 can drive the gear 8 to rotate. The top of the toothed ring 7 is fixedly connected to the bottom of the rotating ring 16, which serves as a limiting effect. The rotating ring 16 is rotatably connected to a second connecting rod 11, which serves as a limiting and load-bearing effect. The second connecting rod 11 is also fixedly connected to the outer wall of the turntable 18, which serves as a fixing effect.

[0026] Reference Figure 2 - Figure 4A motor 12 is fixedly connected to the top outer wall of the liquid-based cell preparation and staining machine body 1. A first sprocket 13 is fixedly connected to the output end of the motor 12. When the motor 12 operates, the first sprocket 13 rotates, driving the second sprocket 14, which is fixedly connected to the top outer wall of the rotating ring 16, to rotate. The outer walls of the first sprocket 13 and the second sprocket 14 are connected by a chain 15, which provides a transmission effect, allowing the first sprocket 13 to drive the second sprocket 14 to rotate. A first connecting rod 6 is rotatably connected to the outer wall of the turntable 18, providing a limiting effect for the turntable 18. The first connecting rod 6 is also fixedly connected to the top outer wall of the top cover 2, providing a fixing effect. The cleaning rod 9 is adapted to the size of the test tube 4 and can clean the inner wall of the test tube 4.

[0027] Working principle: Open the top cover 2 of the liquid-based cell preparation and staining machine body 1, place the test tube 4 containing the cell sample on top of the sedimentation chamber 3. At this time, the cleaning rod 9 is located outside the test tube 4, and the gear 8, turntable 18 and other components are in the initial state. Start the motor 12. The output end of the motor 12 drives the first sprocket 13 to rotate. The first sprocket 13 is connected to the second sprocket 14 through the chain 15, which in turn drives the second sprocket 14 to rotate. Since the second sprocket 14 is fixed on the top outer wall of the rotating ring 16, the rotating ring 16 rotates accordingly. When the rotating ring 16 rotates, its outer wall slides in the inner wall of the turntable 18. At the same time, the rotating ring 16 is connected to the turntable 18 through the second connecting rod 11, so that the turntable 18 rotates in the inner wall of the sealing ring plate 5. If the connecting plate 17 is inserted into the inner wall of the rotating ring 16 and the sealing ring plate 5, the rotation of the rotating ring 16 will drive the sealing ring plate 5 to rotate together. In this way, the relative position of the two cleaning rods 9 can be controlled. If the connecting plate 17 is not inserted, the rotating ring 16 rotates independently. The toothed ring 7 fixedly connected to the bottom of the rotating ring 16 rotates together with the rotating ring 16. The toothed ring 7 meshes with the gear 8, thereby driving the gear 8 to rotate. The cleaning rod 9 fixedly connected to the outer wall of the gear 8 rotates accordingly. Since the cleaning rod 9 is adapted to the size of the test tube 4, the rotating cleaning rod 9 can physically clean the inner wall of the test tube 4. When a more thorough cleaning is required, the ultrasonic transducer 10 at the bottom of the cleaning rod 9 can be turned on. The ultrasonic transducer 10 generates high-frequency vibration, which generates tiny bubbles in the liquid. When the bubbles burst, they generate a strong impact force, which works in conjunction with the physical cleaning of the cleaning rod 9 to remove stubborn stains and cell residues from the inner wall and bottom of the test tube 4. After completing the test tube cleaning operations, the top cover 2 is closed, and the sedimentation chamber 3 slides downward in the inner wall of the liquid-based cell preparation and staining machine body 1 to perform subsequent liquid-based cell preparation and staining operations such as transfer and sedimentation preparation.

[0028] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. The centrifugation mechanism of a fully automated liquid-based cell preparation and staining machine, comprising the main body of the liquid-based cell preparation and staining machine (1), characterized in that: The liquid-based cell preparation and staining machine body (1) is hinged to a top cover (2) on its outer wall. The inner wall of the liquid-based cell preparation and staining machine body (1) is slidably connected to a sedimentation chamber (3). A test tube (4) is placed on the top of the sedimentation chamber (3). A gear (8) is rotatably connected to the outer wall of the top cover (2). A cleaning rod (9) is fixedly connected to the outer wall of the gear (8). A sealing ring plate (5) is fixedly connected to the inner wall of the top cover (2). A turntable (18) is slidably connected to the inner wall of the sealing ring plate (5). A connecting plate (17) is inserted into the inner wall of the sealing ring plate (5). A rotating ring (16) is inserted into the outer wall of the connecting plate (17). A motor (12) is fixedly connected to the top outer wall of the liquid-based cell preparation and staining machine body (1). A first sprocket (13) is fixedly connected to the output end of the motor (12). A second sprocket (14) is fixedly connected to the top outer wall of the rotating ring (16).

2. The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine according to claim 1, characterized in that: An ultrasonic transducer (10) is fixedly connected to the bottom end of the cleaning rod (9).

3. The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine according to claim 2, characterized in that: The outer wall of the rotating ring (16) is slidably connected to the inner wall of the turntable (18).

4. The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine according to claim 3, characterized in that: The rotating ring (16) is rotatably connected to a second connecting rod (11), which is also fixedly connected to the outer wall of the turntable (18).

5. The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine according to claim 4, characterized in that: The outer walls of the first sprocket (13) and the second sprocket (14) are connected by a chain (15).

6. The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine according to claim 5, characterized in that: The turntable (18) is rotatably connected to a first connecting rod (6), which is also fixedly connected to the outer wall of the top of the top cover (2).

7. The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine according to claim 6, characterized in that: The cleaning rod (9) is adapted to the size of the test tube (4).

8. The centrifugation mechanism of the fully automated liquid-based cell preparation and staining machine according to claim 7, characterized in that: The outer wall of the gear (8) is meshed with a toothed ring (7), and the top of the toothed ring (7) is fixedly connected to the bottom of the rotating ring (16).