Slide cleaning device

Abstract

The utility model discloses a slide cleaning device, which belongs to the field of immunohistochemical staining and comprises a cleaning module, two flow channels are arranged in a nozzle, each flow channel comprises a vertical section and an inclined section, the inclined section extends out from the tail end of the vertical section, an included angle is formed between the inclined section and the vertical section, a nozzle is formed at the tail end of the inclined section, and the nozzle is linear. The driving assembly is installed on the support, the nozzle is in transmission connection with the driving assembly, the driving assembly drives the nozzle to move relative to the support, the pump valve module comprises a driving pump assembly, a pneumatic control assembly and a hydraulic control assembly, the driving pump assembly comprises an air pump and a liquid pump, the pneumatic control assembly comprises an air valve, and the hydraulic control assembly comprises a hydraulic valve; the air valve is communicated with one flow channel of the nozzle through a pipeline, the air pump controls pressure and flow of air in the flow channel, the liquid pump is connected with the liquid valve through a pipeline, the liquid valve is communicated with the other flow channel of the nozzle through a pipeline, and the liquid pump controls pressure and flow of liquid in the flow channel.

Description

Technical Field

[0001] This utility model relates to the field of immunohistochemical staining, and in particular to a slide cleaning device. Background Technology

[0002] Immunohistochemical staining equipment essentially automates the immunohistochemical process through the cooperation of computers and various mechanical devices. In the entire immunohistochemical staining process, multiple different reagents need to be added to the slides for reaction. Each time a new reagent is added, the previously residual reagents need to be rinsed and dried. Therefore, slide cleaning plays a particularly important role in the immunohistochemical process. Its efficiency and rinsing effect directly affect the overall immunohistochemical process time and the final staining effect.

[0003] Current domestic research on cleaning systems for immunohistochemical staining equipment mainly focuses on high-throughput immunohistochemical pathological diagnosis. The slide cleaning is mostly based on the capillary siphon principle. This method has disadvantages such as small liquid rinsing flow, poor rinsing effect, and inability to adjust the rinsing flow and rinsing liquid pressure as needed. Utility Model Content

[0004] In order to overcome the shortcomings of the prior art, one of the objectives of this utility model is to provide a glass slide cleaning device with a large flow rate and adjustable rinsing flow rate and pressure.

[0005] One of the objectives of this utility model is achieved through the following technical solution:

[0006] A slide cleaning device includes a cleaning module, which includes a nozzle with two flow channels. Each flow channel includes a vertical section and an inclined section. The inclined section extends from the end of the vertical section, forming an angle with the vertical section. The end of the inclined section forms a nozzle, which is in a straight line shape. The cleaning module also includes a support and a drive assembly. The drive assembly is mounted on the support, and the nozzle is driven by the drive assembly. The drive assembly drives the nozzle to move relative to the support. The slide cleaning device also includes a pump and valve module, which includes a drive pump assembly, a pneumatic control assembly, and a liquid control assembly. The drive pump assembly includes an air pump and a liquid pump. The pneumatic control assembly includes an air valve, and the liquid control assembly includes a liquid valve. The air pump is connected to the air valve via a pipeline, and the air valve is connected to one flow channel of the nozzle via a pipeline. The air pump controls the pressure and flow rate of the gas in the flow channel. The liquid pump is connected to the liquid valve via a pipeline, and the liquid valve is connected to the other flow channel of the nozzle via a pipeline. The liquid pump controls the pressure and flow rate of the liquid in the flow channel.

[0007] Furthermore, the number of nozzles is multiple, the air control assembly also includes an air distribution block, the number of air valves and the number of outlets of the air distribution block are the same as the number of nozzles, the air pump is connected to the inlet of the air distribution block, and the outlet of each air distribution block is connected to an air valve.

[0008] Furthermore, the liquid control assembly also includes a liquid distribution block, the number of liquid valves and the number of outlets of the liquid distribution block are the same as the number of nozzles, the liquid pump is connected to the inlet of the liquid distribution block, and the outlet of each liquid distribution block is connected to a liquid valve.

[0009] Furthermore, the drive assembly includes a drive member, a drive wheel, a driven wheel, and a transmission belt. The drive member is fixed to the bracket, the drive wheel is mounted on the output end of the drive member, the driven wheel is rotatably mounted on the bracket, the transmission belt is sleeved between the drive wheel and the driven wheel, and the nozzle is mounted on the transmission belt.

[0010] Furthermore, the drive assembly also includes a mounting bracket and a connecting plate, the connecting plate being fixedly connected to the mounting bracket, the nozzle being fixed to the mounting bracket, and the connecting plate being fixedly connected to the transmission belt.

[0011] Furthermore, the driving component also includes a position detection component, which includes an optocoupler and a baffle. The optocoupler is fixed to the bracket, and the baffle is fixed to the connecting plate. When the nozzle moves to the initial position, the baffle moves to the optocoupler to generate a trigger signal.

[0012] Furthermore, the driving assembly also includes a sliding assembly, which includes a slide rail and a slider. The slide rail is fixed to the bracket, and the slider is fixed to the connecting plate. The slider cooperates with the slide rail.

[0013] Furthermore, the extension direction of the slide rail is the same as the length direction of the glass slide.

[0014] Furthermore, the support includes a top plate and two side plates, with the two side plates fixed to both sides of the top plate. The cleaning module also includes a fixing plate and a fixing frame, with both ends of the fixing plate fixed to the two side plates respectively. The fixing frame is located between the top plate and the fixing plate, the driving component is fixed to the fixing frame, and the driving wheel, the driven wheel, and the transmission belt are located between the fixing frame and the fixing plate.

[0015] Furthermore, the top plate is provided with multiple through slots, the nozzle is located between the top plate and the fixed plate, and the pipeline is connected to the nozzle through the through slots.

[0016] Compared with existing technologies, the glass slide cleaning device of this invention has the following advantages:

[0017] (1) Each flow channel includes a vertical section and an inclined section. The inclined section extends from the end of the vertical section and forms an angle with the vertical section. This flow channel design allows water or air to fill the vertical section first when it enters the flow channel, and then spray out from the inclined section, resulting in a smooth liquid flow.

[0018] (2) The nozzle is in a straight line shape, with a large liquid volume, high cleaning efficiency, and good cleaning effect;

[0019] (3) The air pump controls the pressure and flow rate of the gas in the flow channel, and the liquid pump controls the pressure and flow rate of the liquid in the flow channel, so that the flushing flow rate and pressure of the cleaning device are adjustable.

[0020] (4) The drive assembly drives the nozzle to move relative to the bracket to achieve automatic cleaning;

[0021] (5) There are multiple nozzles. The air control component also includes air distribution blocks. The number of air valves and the number of outlets of the air distribution blocks are the same as the number of nozzles. The air pump is connected to the inlet of the air distribution block. The outlet of each air distribution block is connected to an air valve. Each cleaning channel is independently controlled without interference, which can meet the multi-channel and multi-cleaning needs of the slide cleaning equipment. Attached Figure Description

[0022] Figure 1 This is a perspective view of the glass slide cleaning device of this utility model;

[0023] Figure 2 for Figure 1 A three-dimensional view of the pump and valve module of the glass slide cleaning device;

[0024] Figure 3 for Figure 1 A three-dimensional view of the cleaning module of the glass slide cleaning device;

[0025] Figure 4 for Figure 3 A schematic diagram of the internal structure of the cleaning module;

[0026] Figure 5 for Figure 3 A partial three-dimensional view of the cleaning module;

[0027] Figure 6 for Figure 3 A 3D view of the nozzles of the cleaning module;

[0028] Figure 7 for Figure 6 A three-dimensional sectional view of the nozzle.

[0029] In the diagram: 10. Pump and valve module; 11. Drive pump assembly; 110. First mounting plate; 111. Air pump; 112. Liquid pump; 113. Mixing pump; 12. Pneumatic control assembly; 121. Second mounting plate; 122. Air valve; 123. Air distribution block; 13. Liquid control assembly; 131. Second mounting plate; 132. Liquid valve; 133. Liquid distribution block; 14. Waste liquid valve; 20. Cleaning module; 21. Bracket; 210. Top plate; 2101. Through groove; 211. Side plate; 212. Support plate; 22. Fixing 23. Plate; 24. Fixing frame; 25. Drive assembly; 26. Drive component; 27. Drive wheel; 28. Drive wheel; 29. ​​Drive belt; 20. Mounting bracket; 21. Connecting plate; 22. Position detection assembly; 23. Optical coupler; 24. Baffle; 244. Sliding assembly; 25. Slide rail; 26. Slider; 27. Nozzle; 28. Main body; 29. ​​Connector; 20. Flow channel; 21. Connecting part; 22. Vertical section; 23. Inclined section; 24. Nozzle. Detailed Implementation

[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0031] It should be noted that when a component is said to be "fixed to" another component, it can be directly on the other component or it can be fixed through another intermediate component. When a component is said to be "connected to" another component, it can be directly connected to the other component or it may be fixed through another intermediate component. When a component is said to be "set on" another component, it can be set directly on the other component or it may be set through another intermediate component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.

[0032] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0033] Please see Figure 1 The slide cleaning device includes a pump and valve module 10 and a cleaning module 20.

[0034] Please continue reading. Figure 2 The pump and valve module 10 includes a drive pump assembly 11, a pneumatic control assembly 12, a hydraulic control assembly 13, and a waste liquid valve 14.

[0035] The drive pump assembly 11 includes a first mounting plate 110, an air pump 111, a liquid pump 112, and a mixing pump 113, all of which are fixed to the first mounting plate 110. The air pump 111 provides high-pressure, high-flow-rate positive pressure gas, and its flow rate is adjustable. The liquid pump 112 provides the liquid used for rinsing, and its flow rate is adjustable. The mixing pump 113, in conjunction with a waste liquid valve 14, provides a certain negative pressure within the hose pipeline and can pump out the liquid remaining in the container. The mixing pump 113 can also extract waste liquid generated during the cleaning process of the cleaning module 20 via the pipeline.

[0036] The pneumatic control assembly 12 includes a second mounting plate 121, air valves 122, and a gas distribution block 123. The air valves 122 and the gas distribution block 123 are fixed to the second mounting plate 121. The gas distribution block 123 has one inlet and multiple outlets. The gas distribution block 123 diverts the gas generated by the air pump 111. In this embodiment, the gas distribution block 123 divides the gas generated by the air pump 111 into six paths. The inlet of the gas distribution block 123 is connected to the air pump 111, and the outlet of the gas distribution block 123 is connected to multiple air valves 122. In this embodiment, there are six air valves 122. The air valves 122 control the opening and closing of the gas paths after diversion by the gas distribution block 123, and can open or close each gas path according to control commands.

[0037] The liquid control assembly 13 includes a second mounting plate 131, liquid valves 132, and a liquid distribution block 133. The liquid valves 132 and the liquid distribution block 133 are fixed to the second mounting plate 131. The liquid distribution block 133 has one inlet and multiple outlets. The liquid distribution block 133 diverts the liquid generated by the liquid pump 112. In this embodiment, the liquid distribution block 133 divides the gas generated by the liquid pump 112 into six paths. The inlet of the liquid distribution block 133 is connected to the liquid pump 112, and the outlet of the liquid distribution block 133 is connected to multiple liquid valves 132. In this embodiment, the number of liquid valves 132 is six. The liquid valves 132 control the on / off state of the cleaning liquid paths after diversion by the liquid distribution block 133, and can open or close each cleaning liquid path according to control commands.

[0038] Waste liquid valve 14 is connected to mixing pump 113. Mixing pump 113 can provide a certain negative pressure in the hose pipeline and can pump the liquid remaining in the container. Mixing pump 113 can extract the waste liquid generated during the cleaning process of cleaning module 20 through the pipeline.

[0039] Please continue reading. Figure 1 , Figures 3 to 5The cleaning module 20 includes a bracket 21, a fixing plate 22, a fixing frame 23, a drive assembly 24, and a nozzle 25.

[0040] The support 21 includes a top plate 210, two side plates 211, and a support plate 212. The top plate 210 has multiple through slots 2101 for pipe passage. The number of through slots 2101 is equal to the number of nozzles 25. The two side plates 211 extend from both sides of the top plate 210 and are perpendicular to it. The support plate 212 is fixed to the inner side of the bottom of the side plates 211. The support plate 212 is triangular in shape and is used to strengthen the structural strength of the support 21.

[0041] The fixing plate 22 is fixed to the two side plates 211 at both ends. The fixing plate 22 is parallel to the top plate 210. The fixing plate 22 is used to install the drive assembly 24.

[0042] The fixing bracket 23 is fixed to the fixing plate 22, and the fixing bracket 23 is located between the fixing plate 22 and the top plate 210. The fixing bracket 23 is U-shaped and is used to fix the driving component 240.

[0043] The drive assembly 24 is used to drive the nozzle 25, and the number of drive assemblies 24 is the same as the number of nozzles 25. Each drive assembly 24 drives one nozzle 25 to move relative to the support 21 in the width direction (the length direction of the slide).

[0044] The drive assembly 24 includes a drive element 240, a drive wheel 241, a driven wheel 242, a transmission belt 243, a mounting bracket 245, a connecting plate 246, a position detection assembly 247, and a sliding assembly 248.

[0045] A drive component 240 is fixed to a mounting bracket 23 and provides power for the movement of the nozzle 25. In this embodiment, the drive component 240 is a motor. A drive wheel 241 is mounted on the output end of the drive component 240, a driven wheel 242 is rotatably mounted on a mounting plate 22, and a transmission belt 243 is sleeved between the drive wheel 241 and the driven wheel 242. A mounting bracket 245 is used to mount the nozzle 25 and drive the nozzle 25 to move. A connecting plate 246 is fixed to the mounting bracket 245 and cooperates with the transmission belt 243. When the transmission belt 243 rotates, it drives the connecting plate 246 to move. The position detection component 247 includes an optocoupler 2471 and a baffle 2472. The optocoupler 2471 is fixed to the fixed plate 22, and the baffle 2472 is fixed to the connecting plate 246. The baffle 2472 moves with the nozzle 25. When the nozzle 25 moves to the zero position, the baffle 2472 moves to the optocoupler 2471 to determine the zero point. This ensures accurate displacement of the moving component after the control unit issues a position command, thereby controlling the air pump 111 or the liquid pump 112 to start. The sliding component 248 includes a slide rail 2481 and a slider 2482. The slider 2482 is fixed to the bottom of the connecting plate 246, and the slide rail 2481 is fixed to the fixed plate 22. The slider 2482 cooperates with the slide rail 2481 to allow the nozzle 25 to slide on the fixed plate 22.

[0046] Please continue reading. Figure 6 as well as Figure 7 The nozzle 25 includes a main body 250 and two connectors 251 mounted on the main body 250. One connector 251 is connected to a gas valve 122, and the other connector 251 is connected to a liquid valve 132. The main body 250 has two flow channels 252, one for gas and the other for liquid. Each flow channel 252 includes a connecting portion 253, a vertical section 254, and an inclined section 255. The vertical section 254 is located between the connecting portion 253 and the inclined section 255. The connecting portion 253 has internal threads and is used to install the connector 251. The vertical section 254 is vertically positioned and perpendicular to the horizontal plane, and the inclined section 255 forms an angle with the vertical section 254. This design ensures that when liquid or gas enters the flow channel 252, it first fills the vertical section 254 and then exits from the inclined section 255, resulting in a stable flow rate. The narrowing at the end of the inclined section 255 increases the gas or liquid flow velocity within the cavity, creating a pressure reduction and flow enhancement effect. The end of the inclined section 255 forms a nozzle 256, which is straight-line shaped, resulting in a large flow rate from the nozzle 25 and high cleaning efficiency. The liquid nozzle is in front, followed by the gas nozzle, which dries any residual liquid at the liquid nozzle.

[0047] When using the slide cleaning device, the control unit issues a cleaning command. The corresponding channel drive 240 of the cleaning module 20 starts according to the cleaning command. Driven by the drive 240, the driving wheel 241 starts to rotate, and at the same time, the driven wheel 242 is driven to rotate through the transmission belt 243. At this time, the mounting bracket 245 fixed on the transmission belt 243 slides on the slide rail 2481 under the drive of the transmission belt 243. The nozzle 25 also moves with the mounting bracket 245 until it is fixed in position. Then, the liquid pump 112 in the pump and valve module 10 starts. The cleaning fluid is pumped out to the corresponding channel nozzle 25 through the pipeline via the liquid pump 112, the liquid distribution block 133, and the liquid valve 132 to clean the slide. After cleaning, if there are no other channel slides to be cleaned, the liquid pump 112 and the liquid valve 132 are closed. If there are other channel slides to be cleaned, the other channels are cleaned repeatedly. The aforementioned drive unit 240 moves according to the command, switching the cleaning fluid to other channels via the liquid valve 132; the waste liquid generated during cleaning is pumped to the waste liquid storage container via the pipeline, waste liquid valve 14, and mixing pump 113; then, under the command of the control unit, the drive unit 240 drives the nozzle 25 to move towards the initial position of the glass slide until the optocoupler is at zero position. At this time, the air pump 111 in the pump valve module 20 starts, and the gas is transmitted to the nozzle 25 through the pipeline via the gas distribution block 123 and the air valve 122. The gas is released at a certain pressure and a certain cross section by the nozzle 25, which reduces pressure and increases flow. At this time, under the command of the control unit, the drive unit 240 starts, driving the nozzle 25 to dry the residual liquid on the glass slide surface. The residual liquid on the glass slide surface is blown by the nozzle 25 to the waste liquid tank, and then pumped to the waste liquid storage container via the pipeline, waste liquid valve 14, and mixing pump 113, thus completing one cleaning process.

[0048] Each flow channel 252 of the slide cleaning device of this application includes a vertical section 254 and an inclined section 255. The inclined section 255 extends from the end of the vertical section 254, and the inclined section 255 forms an angle with the vertical section 254. This design of the flow channel 252 ensures that when water or air enters the flow channel 252, it first fills the vertical section 254 and then sprays out from the inclined section 255, resulting in a smooth liquid flow. The nozzle 256 is in a straight line shape, providing a large liquid volume, high cleaning efficiency, and good cleaning effect. The air pump 111 controls the pressure and flow rate of the gas in the flow channel 252, and the liquid pump 112 controls the liquid in the flow channel 252. The pressure and flow rate of the body allow for adjustable rinsing flow and pressure of the cleaning device; the drive assembly 24 drives the nozzles 25 to move relative to the support 21, achieving automatic cleaning; there are multiple nozzles 25, and the pneumatic control assembly 12 also includes air distribution blocks 123. The number of air valves 122 and the number of outlets of the air distribution blocks 123 are the same as the number of nozzles 25. The air pump 111 is connected to the inlet of the air distribution blocks 123, and the outlet of each air distribution block 123 is connected to an air valve 122. Each cleaning channel is independently controlled without interference, which can meet the multi-channel and multi-cleaning needs of slide cleaning equipment. The slide cleaning device has a frame structure and can be adapted to various immunohistochemistry equipment.

[0049] The above embodiments only illustrate several implementation methods of this utility model, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the utility model patent. It should be noted that for those skilled in the art, several modifications and improvements can be made without departing from the concept of this utility model. These are all equivalent modifications and improvements made to the above embodiments based on the essential technology of this utility model, and all of these fall within the protection scope of this utility model.

Claims

1. A glass slide cleaning device, comprising a cleaning module, wherein the cleaning module includes nozzles, characterized in that: The nozzle has two flow channels, each flow channel including a vertical section and an inclined section. The inclined section extends from the end of the vertical section, forming an angle with the vertical section. The end of the inclined section forms a nozzle, which is in a straight line shape. The cleaning module also includes a bracket and a drive assembly. The drive assembly is mounted on the bracket, and the nozzle is driven by the drive assembly. The drive assembly drives the nozzle to move relative to the bracket. The slide cleaning device also includes a pump and valve module. The pump and valve module includes a drive pump assembly, a pneumatic control assembly, and a liquid control assembly. The drive pump assembly includes an air pump and a liquid pump. The pneumatic control assembly includes an air valve, and the liquid control assembly includes a liquid valve. The air pump is connected to the air valve through a pipeline, and the air valve is connected to one flow channel of the nozzle through a pipeline. The air pump controls the pressure and flow rate of the gas in the flow channel. The liquid pump is connected to the liquid valve through a pipeline, and the liquid valve is connected to the other flow channel of the nozzle through a pipeline. The liquid pump controls the pressure and flow rate of the liquid in the flow channel.

2. The slide cleaning apparatus according to claim 1, characterized in that: The number of nozzles is multiple, the air control assembly also includes an air distribution block, the number of air valves and the number of outlets of the air distribution block are the same as the number of nozzles, the air pump is connected to the inlet of the air distribution block, and the outlet of each air distribution block is connected to an air valve.

3. The slide cleaning apparatus according to claim 2, characterized in that: The liquid control assembly also includes a liquid distribution block. The number of liquid valves and the number of outlets of the liquid distribution block are the same as the number of nozzles. The liquid pump is connected to the inlet of the liquid distribution block, and the outlet of each liquid distribution block is connected to one of the liquid valves.

4. The slide cleaning apparatus according to claim 1, characterized in that: The drive assembly includes a drive component, a drive wheel, a driven wheel, and a transmission belt. The drive component is fixed to the bracket, the drive wheel is installed at the output end of the drive component, the driven wheel is rotatably installed on the bracket, the transmission belt is sleeved between the drive wheel and the driven wheel, and the nozzle is installed on the transmission belt.

5. The slide cleaning apparatus according to claim 4, characterized in that: The drive assembly also includes a mounting bracket and a connecting plate. The connecting plate is fixedly connected to the mounting bracket, the nozzle is fixed to the mounting bracket, and the connecting plate is fixedly connected to the transmission belt.

6. The slide cleaning apparatus according to claim 5, characterized in that: The drive assembly further includes a position detection assembly, which includes an optocoupler and a baffle. The optocoupler is fixed to the bracket, and the baffle is fixed to the connecting plate. When the nozzle moves to the initial position, the baffle moves to the optocoupler to generate a trigger signal.

7. The slide cleaning apparatus according to claim 5, characterized in that: The driving component further includes a sliding component, which includes a slide rail and a slider. The slide rail is fixed to the bracket, and the slider is fixed to the connecting plate. The slider cooperates with the slide rail.

8. The slide cleaning apparatus according to claim 7, characterized in that: The slide rail extends in the same direction as the length of the glass slide.

9. The slide cleaning apparatus according to claim 4, characterized in that: The support includes a top plate and two side plates. The two side plates are fixed to the two sides of the top plate. The cleaning module also includes a fixing plate and a fixing frame. The two ends of the fixing plate are respectively fixed to the two side plates. The fixing frame is located between the top plate and the fixing plate. The driving component is fixed to the fixing frame. The driving wheel, the driven wheel and the transmission belt are located between the fixing frame and the fixing plate.

10. The slide cleaning apparatus according to claim 9, characterized in that: The top plate is provided with multiple through slots, the nozzle is located between the top plate and the fixed plate, and the pipeline is connected to the nozzle through the through slots.

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