Contact type reaction device
By designing the limiting plate and clamping assembly of the contact reaction device, the problems of stable clamping of the cover plate and chip and control of solution volume in in vitro biochip detection were solved, thereby improving the detection effect and reducing the cost.
Patent Information
- Application Number
- CN202423058380.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-11
- Publication Date
- 2026-02-24
- Estimated Expiration
- 2034-12-11
AI Technical Summary
Existing biochip in vitro detection devices face challenges in controlling the volume of staining or hybridization processes, leading to waste and contamination of coverslips or chips, and requiring large volumes of staining or hybridization solutions, which increases costs.
A contact reaction device was designed, which consists of a base, a limiting plate, a chip, a cover plate, and a clamping assembly. The chip and the cover plate are fixed by the limiting plate, and the pressure plate, connecting rod, and torsion spring structure of the clamping assembly are used to achieve stable clamping between the cover plate and the chip, so as to accurately control the solution volume and the reaction area.
It enables precise control of solution volume and reaction area, improves detection results, reduces detection costs, and ensures stable clamping of the cover plate and chip, facilitating stable reaction and use.
Smart Images
Figure CN223936493U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of in vitro detection technology, and more particularly to a contact reaction device. Background Technology
[0002] In the process of in vitro biochip detection, the biochip reaction device used for in vitro detection uses a chip and a cover plate.
[0003] Existing technologies using conventional coverslips present challenges in achieving zoned or micro-volume operations during staining or hybridization, leading to waste or contamination of the coverslips or chips. Furthermore, they require large volumes of staining or hybridization solutions, increasing detection costs. Therefore, this invention proposes a contact reaction device. Utility Model Content
[0004] In view of the above problems, this application provides a contact reaction device to solve the problems of inconvenient control and waste in the prior art.
[0005] This application provides a contact reaction device, including a base. The base has a concave cross-section and four limiting plates are symmetrically fixedly connected to the top surface. A chip and a cover are disposed between two limiting plates on the same side. A pressing component is disposed on the upper side of the cover.
[0006] In some embodiments, the clamping assembly includes a pressure plate, and two connecting rods are symmetrically and movably connected to the side wall of the pressure plate. The connecting rods are Z-shaped and one end is movably connected to the side wall of the base. A torsion spring is movably connected to the center of the side wall of the pressure plate. A movable plate is fixedly connected to the end of the torsion spring away from the pressure plate. A fixed rod is sleeved at the center of the torsion spring. The fixed rod is fixedly connected to the base. The movable plate is movably connected to the fixed rod. A side plate is fixedly connected to the end of the movable plate away from the fixed rod. Through slots are formed on the left and right side walls of the base, and one side of the side plate is inserted into the through slot.
[0007] In some embodiments, the cross-section of the pressure plate is inverted concave, and the length and width of the bottom surface of the pressure plate are smaller than the length and width of the cover plate.
[0008] In some embodiments, a support plate is fixedly connected to the side wall of each of the two connecting rods, and another support plate is fixedly connected to the end of the fixed rod near the pressure plate. The support plate is fixedly connected to the base.
[0009] In some embodiments, four reaction stages are evenly distributed on the sidewall of the cover plate near the chip, and a sample application hole is provided at one corner of the four reaction stages, the sample application hole penetrating the upper and lower sidewalls of the cover plate.
[0010] In some embodiments, a horizontal plate is fixedly connected to both sides of the cover plate, and the height of the horizontal plate is greater than the height of the reaction table.
[0011] The above scheme involves selecting a cover plate with a specified height and placing the chip between two limiting plates, so that the reaction stage faces the chip. Solution is added through the sample inlet, and the solution enters the area between the reaction stage and the chip through the sample inlet, achieving precise control over the solution volume and reaction area. This not only improves the detection effect but also effectively reduces the detection cost. The operator pushes the side plate, which drives the movable plate to move. The movable plate rotates with a torsion spring, which in turn drives the pressure plate to rotate. At this time, the connecting rods on both sides rotate together, which allows the pressure plate to press the cover plate. When the side plate rotates to the specified angle, one side of the side plate is inserted into the through groove to achieve the positioning and pressing of the pressure plate, so that the cover plate and the chip are stably pressed together, facilitating stable reaction and use.
[0012] The above description is merely an overview of the technical solutions of the embodiments of this application. In order to better understand the technical means of the embodiments of this application and to implement them in accordance with the contents of the specification, and to make the above and other objects, features and advantages of the embodiments of this application more obvious and understandable, specific implementation methods of this application are described below. Attached Figure Description
[0013] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0014] Figure 1 This is a schematic diagram of the overall three-dimensional structure of this application;
[0015] Figure 2 This is a three-dimensional structural diagram of the clamping component of this application;
[0016] Figure 3 This is a three-dimensional structural diagram of the limiting plates in this application;
[0017] Figure 4 This is a three-dimensional structural diagram of the cover plate of this application.
[0018] Explanation of reference numerals in the attached figures:
[0019] 1. Base; 2. Limiting plate; 3. Chip; 4. Cover plate; 5. Clamping assembly; 6. Pressure plate; 7. Connecting rod; 8. Torsion spring; 9. Movable plate; 10. Fixing rod; 11. Side plate; 12. Through groove; 13. Support plate; 14. Reaction table; 15. Sample dispensing hole; 16. Horizontal plate. Detailed Implementation
[0020] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0021] The terms "comprising" and "having," and any variations thereof, in the specification, claims, and drawings of this application are intended to cover without excluding other meanings. The words "a" or "an" do not exclude the presence of multiples. Unless otherwise stated, "multiple" means two or more (including two), and similarly, "multiple sets" means two or more (including two sets).
[0022] The directional terms appearing in the following description refer to the directions shown in the figures and are not intended to limit the specific structure of this application. For example, in the description of this application, terms such as "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "inner," "outer," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the figures. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.
[0023] Furthermore, descriptions of directions used to explain the operation and construction of the components in this embodiment, such as height, are not absolute but relative. Although these directions are appropriate when the components are in the positions shown in the figure, they should be interpreted differently when these positions change to correspond to the changes.
[0024] In the description of this application, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linkage" should be interpreted broadly. For example, "connection" or "linkage" in mechanical structures can refer to a physical connection, such as a fixed connection, a detachable connection, or an integral connection. In addition to referring to a physical connection, "connection" or "linkage" in circuit structures can also refer to an electrical connection or a signal connection. For example, it can be a direct connection, i.e., a physical connection, or an indirect connection through at least one intermediate component, as long as the circuit is connected. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.
[0025] To facilitate understanding of the technical solutions in the embodiments of this application, the technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings.
[0026] like Figure 1-4 As shown, this application embodiment provides a contact reaction device, including a base 1. The base 1 has a concave cross-section and four limiting plates 2 are symmetrically fixedly connected to the top surface. A chip 3 and a cover plate 4 are disposed between two limiting plates 2 on the same side. Four reaction platforms 14 are evenly distributed on the side wall of the cover plate 4 near the chip 3. A sample addition hole 15 is opened at a corner of the four reaction platforms 14. The sample addition hole 15 is disposed through the upper and lower side walls of the cover plate 4. A horizontal plate 16 is fixedly connected to both sides of the cover plate 4. The height of the horizontal plate 16 is greater than the height of the reaction platform 14.
[0027] In the technical solution of this embodiment, by selecting a cover plate 4 with a specified height horizontal plate 16, the chip 3 is placed between two limiting plates 2, so that the reaction stage 14 faces the chip 3. The solution is added through the sample addition hole 15. The solution enters the position between the reaction stage 14 and the chip 3 through the sample addition hole 15, so as to achieve precise control of the solution volume and reaction area, which not only improves the detection effect but also effectively reduces the detection cost.
[0028] A pressing assembly 5 is provided on the upper side of the cover plate 4. The pressing assembly 5 includes a pressure plate 6. Two connecting rods 7 are symmetrically and movably connected on the side wall of the pressure plate 6. The connecting rods 7 are arranged in a Z-shape and one end is movably connected to the side wall of the base 1. A torsion spring 8 is movably connected at the center of the side wall of the pressure plate 6. A movable plate 9 is fixedly connected to the end of the torsion spring 8 away from the pressure plate 6. A fixed rod 10 is sleeved in the center of the torsion spring 8. The fixed rod 10 is fixedly connected to the base 1. The movable plate 9 is movably connected to the fixed rod 10. A side plate 11 is fixedly connected to the end of the movable plate 9 away from the fixed rod 10. Through slots 12 are opened on the left and right side walls of the base 1. One side of the side plate 11 is inserted into the through slot 12.
[0029] In the technical solution of this embodiment, the operator pushes the side plate 11, which drives the movable plate 9 to move. The movable plate 9 rotates with the torsion spring 8, which drives the pressure plate 6 to rotate. At this time, the connecting rods 7 on both sides rotate together, which allows the pressure plate 6 to press the cover plate 4. When the side plate 11 rotates to the specified angle, one side of the side plate 11 is inserted into the through groove 12, which can achieve the positioning of pressing the pressure plate 6, so that the cover plate 4 and the chip 3 are stably pressed together, which is convenient for stable reaction and use.
[0030] Furthermore, the cross-section of the pressure plate 6 is inverted concave, and the length and width of the bottom surface of the pressure plate 6 are smaller than the length and width of the cover plate 4, which can achieve a stable pressing operation on the cover plate 4.
[0031] Furthermore, support plates 13 are fixedly connected to the side walls of both connecting rods 7, and another support plate 13 is fixedly connected to one end of the fixed rod 10 near the pressure plate 6. The support plate 13 is fixedly connected to the base 1, which can make the pressure plate 6 more stable when it rotates.
[0032] Working principle: When using this device, first select a cover plate 4 with a specified height horizontal plate 16, then place the chip 3 between the two limiting plates 2, and place the cover plate 4 on the chip 3 so that the reaction stage 14 faces the chip 3. Add the solution through the sample inlet 15. The solution enters the position between the reaction stage 14 and the chip 3 through the sample inlet 15, realizing precise control of the solution volume and reaction area, which not only improves the detection effect but also effectively reduces the detection cost. After the solution is added, the operator pushes the side plate 11, which drives the movable plate 9 to move. The movable plate 9 rotates with the torsion spring 8, and the torsion spring 8 drives the pressure plate 6 to rotate. At this time, the connecting rods 7 on both sides rotate together, which can make the pressure plate 6 press the cover plate 4. When the side plate 11 rotates to the specified angle, insert one side of the side plate 11 into the through groove 12 to achieve the positioning of the pressure plate 6, so that the cover plate 4 and the chip 3 are stably pressed together, which is convenient for stable reaction and use.
[0033] Those skilled in the art will understand that although some embodiments herein include certain features included in other embodiments but not others, combinations of features from different embodiments are intended to be within the scope of this application and form different embodiments. For example, in the claims, any of the claimed embodiments can be used in any combination.
[0034] The above-described embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this application.
Claims
1. A contact reaction device, characterized in that, Includes a base (1), the cross section of the base (1) is concave and four limiting plates (2) are fixedly connected symmetrically on the top surface. A chip (3) and a cover plate (4) are arranged between two of the limiting plates (2) on the same side. A pressing component (5) is arranged on the upper side of the cover plate (4).
2. The contact reaction device according to claim 1, characterized in that, The clamping assembly (5) includes a pressure plate (6). Two connecting rods (7) are symmetrically and movably connected to the side wall of the pressure plate (6). The connecting rods (7) are arranged in a Z-shape and one end is movably connected to the side wall of the base (1). A torsion spring (8) is movably connected to the center of the side wall of the pressure plate (6). A movable plate (9) is fixedly connected to the end of the torsion spring (8) away from the pressure plate (6). A fixed rod (10) is sleeved in the center of the torsion spring (8). The fixed rod (10) is fixedly connected to the base (1). The movable plate (9) is movably connected to the fixed rod (10). A side plate (11) is fixedly connected to the end of the movable plate (9) away from the fixed rod (10). A through groove (12) is opened on the left and right side walls of the base (1). One side of the side plate (11) is inserted into the through groove (12).
3. The contact reaction device according to claim 2, characterized in that, The cross-section of the pressure plate (6) is inverted concave, and the length and width of the bottom surface of the pressure plate (6) are smaller than the length and width of the cover plate (4).
4. A contact reaction device according to claim 2, characterized in that, Support plates (13) are fixedly connected to the side walls of both connecting rods (7). Another support plate (13) is fixedly connected to one end of the fixed rod (10) near the pressure plate (6). The support plate (13) is fixedly connected to the base (1).
5. A contact reaction apparatus according to claim 1, characterized in that, Four reaction platforms (14) are evenly distributed on the side wall of the cover plate (4) near the chip (3). A sample loading hole (15) is opened at one corner of the four reaction platforms (14). The sample loading hole (15) is set through the upper and lower side walls of the cover plate (4).
6. A contact reaction apparatus according to claim 5, characterized in that, The cover plate (4) is fixedly connected to a horizontal plate (16) near both sides, and the height of the horizontal plate (16) is greater than the height of the reaction table (14).